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Apr 22, 2026, 6:27 PM ET

Pittsburgh Pirates second baseman Brandon Lowe (knee) and first baseman Spencer Horwitz (neck) are both in the starting lineup for Wednesday's game in Texas against the Rangers and right-hander Jack Leiter, according to MLB.com. Lowe is starting at second base and batting second, while Horwitz is at first and batting seventh against Leiter. The left-handed-hitting Lowe didn't play in Tuesday's loss to the Rangers due to left-knee discomfort, and Horwitz was scratched from Tuesday's lineup due to neck discomfort. Neither injury proved to be very serious. The 31-year-old Lowe has gotten off to a pretty nice start in 2026 in his first year in Pittsburgh, slashing .267/.375/.600 with a .975 OPS, seven long balls, 18 RBI, and 12 runs scored in 19 games across 88 plate appearances. For a second baseman in fantasy, he provides a nice power floor that comes with durability concerns. Both Lowe and Horwitz are batting .500 in just two career at-bats apiece against Leiter.--Keith Hernandez
Source: MLB.com
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