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Detroit Pistons forward/center Isaiah Stewart (ankle) is out for Wednesday's game against the Chicago Bulls. Stewart will be out of action for a third consecutive contest due to a left ankle sprain. With Ausar Thompson (ankle) also unavailable, Ron Holland II will likely be in the starting lineup. Unfortunately, Holland has averaged only 7.0 points as a starter, so he has some work to do before landing on fantasy managers' radar.--Andrew Lennox
Source: NBA Injury Report
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Detroit Pistons center Jalen Duren (ankle) won't play on Wednesday against the Bulls. The 21-year-old has played extremely well during the 2025 campaign, averaging 19.4 points, 12.0 rebounds, 1.2 blocks, and 1.1 steals. He was listed as probable on Tuesday night. However, Duren was downgraded to questionable before ultimately getting ruled out. With Isaiah Stewart (ankle) sidelined, the Pistons will likely start Paul Reed at the five. Reed is coming off an eight-point, nine-rebound effort in Monday's overtime win over the Washington Wizards, although it's safe to assume he'll be much more productive for fantasy managers in need of a streaming option.--Dennis Clausen
Source: NBA Injury Report
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Detroit Pistons guard Cade Cunningham (hip) won't play on Wednesday versus the Bulls. The 24-year-old was listed as probable on Tuesday night, but he was quickly downgraded to questionable. He's now ruled out, so his next chance to get on the floor will be on Friday against the visiting Philadelphia 76ers. With Isaiah Stewart (ankle), Ausar Thompson (ankle) and Jalen Duren (ankle) ruled out, the Pistons will need more production from Caris LeVert, Duncan Robinson, Daniss Jenkins, Javonte Green, Ron Holland II, and Paul Reed.--Dennis Clausen
Source: NBA Injury Report
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Charlotte Hornets center Ryan Kalkbrenner (personal) is available for Wednesday's meeting with the Milwaukee Bucks. He was listed as questionable due to personal reasons. In the first 10 games of his NBA rookie campaign, Kalkbrenner has averaged 9.2 points, 6.6 rebounds, 2.3 blocks, and 1.0 steals across 26.6 minutes per contest. The 23-year-old big man has four blocks in his last five appearances. However, he is not a strong fantasy option for this evening.--Andrew Lennox
Source: NBA Injury Report
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Sacramento Kings guard Zach LaVine (thigh) won't suit up on Wednesday versus the visiting Hawks. It's unknown how severe the thigh contusion is, although it's apparently bad enough to force the 30-year-old to miss his second game of the 2025 campaign. Under normal circumstances, Domantas Sabonis (rib) and Malik Monk (ankle) would see a few more scoring opportunities. However, both are questionable, meaning Russell Westbrook and Dennis Schroder might have above-average fantasy showings. Nique Clifford, averaging 7.0 points, 5.5 rebounds, and 1.5 steals in two starts this season, can be considered for streaming purposes for those participating in deeper fantasy formats. LaVine's next chance to play will be on Friday in Minnesota.--Dennis Clausen
Source: NBA Injury Report
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Chicago Bulls guard Josh Giddey (ankle) will be out for Wednesday's road tilt against the Detroit Pistons due to a right-ankle sprain. This evening's matchup will be the second game in a row he will miss. Ayo Dosunmu, Kevin Huerter, and Tre Jones are expected to see additional minutes in his place. Giddey has been excellent this season, averaging 21.4 points, 9.6 rebounds, 9.3 assists, and 1.0 steals in 34.0 minutes per contest. His next opportunity to return comes Sunday against the Jazz.--Andrew Lennox
Source: NBA Injury Report
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Shams Charania of ESPN reports that Philadelphia 76ers forward Paul George (knee) is in the final stage of his return process and will be re-evaluated later this week. George is moving closer to making his season debut, but team doctors want him to build additional strength in his left quadriceps before granting full clearance, per Charania. The veteran forward is coming off an injury-plagued 2024-25 campaign, during which he averaged 16.2 points, 5.3 rebounds, 4.3 assists, and 1.8 steals in 32.0 minutes per contest.--Andrew Lennox
Source: Shams Charania
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According to Keith Pompey of The Philadelphia Inquirer, Philadelphia 76ers center Joel Embiid (knee) doesn't have structural issues in his right knee and is considered day-to-day. Embiid was out of action during Tuesday's win versus the Celtics due to right knee soreness. However, Wednesday's good news for the big man could lead him to play on Friday against the Pistons. If Embiid is unable to suit up, Andre Drummond will likely continue to start at center.--Andrew Lennox
Source: Keith Pompey
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Milwaukee Bucks forward/center Giannis Antetokounmpo (knee) will be unavailable for Wednesday's matchup against the Charlotte Hornets due to left knee patellar tendinopathy. The 30-year-old has missed only one game this season but will sit out tonight for maintenance purposes. Through 10 outings, Antetokounmpo has averaged 33.4 points, 11.9 rebounds, 6.2 assists, and 1.3 blocks across 32.9 minutes per contest. With Giannis sidelined, Ryan Rollins, Kyle Kuzma, and Bobby Portis could all gain a bump in DFS value.--Andrew Lennox
Source: NBA Injury Report
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According to Shams Charania of ESPN, Los Angeles Clippers guard Bradley Beal (hip) has sustained a fracture in his left hip and will undergo season-ending surgery. The injury occurred during Saturday's 114-103 loss to the Suns. Beal was unavailable for Monday's 105-102 loss to the Hawks and further imaging confirmed the fracture. In his shortened first campaign with the Clippers, the 32-year-old struggled to make much of a fantasy impact, averaging 8.2 points and 1.7 assists in 20.0 minutes per game. With Beal now sidelined for the remainder of the season, veteran guards James Harden and Kris Dunn are expected to shoulder increased backcourt responsibilities for Los Angeles.--Andrew Lennox
Source: Shams Charania
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Los Angeles Clippers guard Bradley Beal (hip) will remain out Wednesday against the Nuggets, marking his second straight absence. Head coach Tyronn Lue admitted there's concern Beal could miss additional time. Even when healthy, Beal has struggled to make a fantasy impact, averaging just 8.2 points, 1.7 assists, and 1.2 threes in 20 minutes per game on 37.5 percent shooting. With both Beal and Kawhi Leonard (ankle) sidelined, James Harden should continue to dominate the offense, fresh off a stellar 35-point, 11-assist outing. Kris Dunn is a sneaky short-term add for assists and steals, as his defensive activity and secondary playmaking fit well in the current rotation. Bogdan Bogdanovic and Derrick Jones Jr. should also see bumps in usage. Beal remains a big name but is over-rostered at this point, especially in standard leagues where his floor has been far too low.--Brian Dailisan
Source: Tomer Azarly
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Atlanta Hawks guard Nickeil Alexander-Walker (back) is questionable for Wednesday's matchup against the Kings after missing the last two games. Before the injury, he was thriving in an expanded role without Trae Young, averaging 17.6 points, 3.2 assists, 2.6 rebounds, 1.0 steal, and 2.0 threes in just over thirty minutes per game while shooting 43.8 percent from the field and 85.0 percent from the line. If cleared, Alexander-Walker should reclaim his starting spot and continue as one of Atlanta's top scoring options. If he remains out, Keaton Wallace will likely stay at point guard, offering assists and energy when given steady minutes, while Dyson Daniels shifts to shooting guard with added playmaking responsibility. Vit Krejci and Luke Kennard can also provide three-point help in deeper formats. Alexander-Walker remains a hold across most leagues due to his scoring consistency and opportunity.--Brian Dailisan
Source: NBA Injury Report
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Dallas Mavericks center Dereck Lively II (knee) is questionable for Wednesday against the Suns after missing eight straight games. He opened the season as the team's starting center in the first three contests, averaging 5.3 points, 5.0 rebounds, 3.0 assists, and 1.3 blocks in 17 minutes while shooting 77.8 percent from the field. If he's cleared, expect a low-usage rim runner who boosts field-goal percentage, blocks, and put-backs, though his workload may sit under 20 minutes as Dallas ramps him up. If he sits, Daniel Gafford remains the preferred streamer for rebounds, FG%, and blocks, with Dwight Powell and Moussa Cisse filling spot minutes. With Kyrie Irving (knee) still out and Anthony Davis (calf) questionable, Cooper Flagg and P.J. Washington should continue to handle more touches, making Lively a category specialist rather than a must-start on his first game back.--Brian Dailisan
Source: NBA Injury Report
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Washington Wizards guard Bilal Coulibaly (calf) will remain sidelined Wednesday against the Rockets due to a calf contusion, marking his fourth straight missed game since re-injuring it on Nov. 5. The third-year wing had shown encouraging all-around growth before the setback, averaging 10.5 points, 4.8 rebounds, 3.3 assists, 1.0 steal, 1.0 block, and 1.3 threes in just under 24 minutes per game. In his absence, CJ McCollum has rediscovered his rhythm after an early-season slump, averaging 30.7 points and 6.0 assists over his last three contests while shooting 51 percent from the field and 81 percent at the line. Expect McCollum to continue leading the offense, while Kyshawn George remains a strong fantasy add thanks to his steady scoring, rebounding, and defensive activity. Corey Kispert provides reliable perimeter shooting, and Alexandre Sarr continues to offer value as a rebounding anchor. Coulibaly is a hold only for managers with deep benches.--Brian Dailisan
Source: NBA Injury Report
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Cleveland Cavaliers forward Jaylon Tyson (head) has been ruled out Wednesday against the Miami Heat due to a concussion. It's an untimely setback for Cleveland, who are already missing Darius Garland (toe), Donovan Mitchell (rest), and Evan Mobley (rest). Tyson has quietly been one of the Cavaliers' bright spots, averaging 11.1 points, 4.0 rebounds, 1.8 assists, and 2.2 threes per game on an efficient 48.9 percent shooting from the field and 46.2 percent from deep. He's been producing steady two-way value even when Garland was briefly active, showing poise and defensive versatility. With Tyson sidelined, expect Sam Merrill and De'Andre Hunter to see more wing minutes and perimeter looks, while Lonzo Ball and Craig Porter Jr. handle additional playmaking duties. Tyson's concussion will likely cost him multiple games, making him a hold in deeper formats but a temporary drop candidate in standard leagues if roster flexibility is limited.--Brian Dailisan
Source: NBA Injury Report

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REAL-TIME FANTASY NEWS

Matt Savoie

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Artemi Panarin

Delivers Four Assists in Wednesday's Victory
Simon Nemec

Becomes Hat-Trick Hero Wednesday
Zack MacEwen

Exits Early Wednesday
Cody Glass

Exits With Injury Wednesday
Brandon Hagel

Injured in Wednesday's Loss
Kevin Love

Available Thursday
Ochai Agbaji

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Uncertain for Thursday
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Questionable for Thursday
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Felix Bautista Could Return in Second Half in 2026
Kodai Senga

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Jonathan Kuminga

Won't Return on Wednesday Evening
Paolo Banchero

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Yordan Alvarez

Expected to be Ready for Spring Training
Byron Buxton

Could Waive his No-Trade Clause
Paul Skenes

the Unanimous NL Cy Young Winner
Tarik Skubal

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Bilal Coulibaly

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Nickeil Alexander-Walker

Upgraded To Probable For Matchup Versus Kings
Jonathan Kuminga

Active Wednesday, Not In Starting Lineup
Dereck Lively II

Downgraded to Unavailable on Wednesday
Ja Morant

Unavailable Wednesday
Sam LaPorta

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Isaiah Stewart

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Jalen Duren

Downgraded Versus Chicago
Cade Cunningham

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Ryan Kalkbrenner

Available to Suit Up Wednesday
Zach LaVine

Won't Play on Wednesday Evening
Josh Giddey

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J.K. Dobbins

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Kayshon Boutte

Ruled Out for Thursday Night
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a Game-Time Call Wednesday
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Out on Wednesday
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"Should be Good to Go" on Sunday
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Held Out on Wednesday, Should Fantasy Managers be Worried?
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Officially Ruled Out for Thursday Night
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Practicing, on Track to Return in Week 11?
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Looking Sharp at Practice
Isiah Pacheco

Won't Practice on Wednesday
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Back at Wednesday's Practice
Chris Godwin

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Will Start in Week 11 for Giants
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Won't Practice on Wednesday
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Still No Update on Jermod McCoy's Return Timeline
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Expected to Reclaim Lead-Back Role When Healthy?
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Taylor Montgomery

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Ben Martin

a Risky Play at Bermuda Championship
Mark Hubbard

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Boone Jenner

Exits Win With Upper-Body Injury
Lee Hodges

Searching for a Spark in Bermuda
Frederik Andersen

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Victor Hedman

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Ryan McDonagh

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Tarik Skubal

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Framber Valdez

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Ketel Marte

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Hunter Greene

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Pete Alonso

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Kyle Tucker

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Uros Medic

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