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Who Should I Start for Week 16? Fantasy Football outlooks for Gardner Minshew, Kirk Cousins, Jared Goff, Jaxson Dart, Brock Purdy, C.J. Stroud, Bo Nix, Marcus Mariota, Justin Herbert, Baker Mayfield.
Who Should I Start? Who Should I Sit? Some of the most common Week 16 fantasy football lineup decisions involve players like Gardner Minshew, Kirk Cousins, Jared Goff, Jaxson Dart, Brock Purdy, C.J. Stroud, Bo Nix, Marcus Mariota, Justin Herbert, Baker Mayfield. However, don't worry, we are here to help you make these decisions and build winning lineups in Week 16. Set your optimal fantasy football lineups for Week 16 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
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Fantasy Football Matchup Outlooks
Below are some fantasy football outlooks written by our NFL team here at RotoBaller, bringing you their fantasy football analysis and advice on which players to consider starting in Week 16:
Gardner Minshew, QB, Kansas City Chiefs
Kansas City Chiefs quarterback Gardner Minshew replaced Patrick Mahomes after he suffered his season-ending knee injury against the Los Angeles Chargers last week. Minshew completed three of his five pass attempts for 22 yards and an interception in the loss. It was a difficult spot for the backup to be thrust into, but he should have the opportunity to bounce back this week against the Tennessee Titans. The Titans have given up the seventh-most fantasy points to opposing quarterbacks this season, putting Minshew in an advantageous situation this week.
The last time Minshew started a game was over a year ago when he was a member of the Las Vegas Raiders. The 29-year-old completed 25 of 42 pass attempts (60%) for 230 yards, a touchdown, and an interception in a loss to the Denver Broncos. Minshew has proven to be a capable starter when given the opportunity, but the Kansas City offense should still take a hit without Mahomes at the helm. Minshew is ranked QB26 in our RotoBaller rankings, making him a backend QB2 option in Superflex and 2QB leagues this week.
Kirk Cousins, QB, Atlanta Falcons
Atlanta Falcons quarterback Kirk Cousins has struggled for much of the 2025 season, completing 62.6% of his pass attempts for 1,218 yards, six touchdowns, and three interceptions across seven games (five starts). However, the 37-year-old posted a monster performance in his team's Week 15 upset of the Tampa Bay Buccaneers, throwing for 373 yards and three scores. At this point in his career, Cousins should not be expected to post big numbers every week. Still, his showing against Tampa Bay proves that the veteran still carries some production upside in the right matchups.
The Falcons will face another favorable opponent in Week 16 against the Arizona Cardinals, followed by a far more difficult test in Week 17 against the Los Angeles Rams. For fantasy managers in two-quarterback formats, Cousins could be a solid streamer at the position, particularly in Week 16.
Marcus Mariota, QB, Washington Commanders
Washington Commanders quarterback Marcus Mariota has a tough matchup in Week 16 against his former team, the Philadelphia Eagles. Mariota will remain Washington's starter for the remainder of the regular season after the team shut down Jayden Daniels (elbow) after aggravating his elbow injury in Week 14. The 32-year-old signal-caller has been solid all season while filling in for Daniels, completing 62% of his passes for 1,600 yards, 10 touchdowns, and seven interceptions while adding 49 carries for 298 yards and a touchdown as a runner in 10 games (seven starts).
Mariota is averaging 18.4 fantasy points per game in his seven starts, which would be tied for QB11 on the season among quarterbacks with at least six games. Mariota profiles as a QB2 on Saturday against an Eagles defense that has allowed the 10th-fewest fantasy points per game to quarterbacks.
Brock Purdy, QB, San Francisco 49ers
San Francisco 49ers quarterback Brock Purdy's season-long numbers don't jump off the page, as he's completed 67.9% of his pass attempts for 1,442 yards, 12 touchdowns, and seven interceptions across six starts. However, the 25-year-old is coming off one of his best performances of the season, throwing for 295 yards and three touchdowns in a Week 15 win over the Tennessee Titans. Purdy also rushed for a season-high 44 yards against Tennessee, which may be an indication he's finally regaining full health after missing nearly two full months in the middle of the year with a lingering toe injury.
The 49ers travel to Indianapolis to face the Colts in Week 16 before returning home to host the Chicago Bears in Week 17. Purdy has solid fantasy QB1 upside for the final weeks of the season, particularly if he continues to weaponize his rushing ability.
Who Should I Start Tool
You can also see the Who Should I Start tool here.
Week 16 Player Decisions. Today's focus is on specific players - Gardner Minshew, Kirk Cousins, Jared Goff, Jaxson Dart, Brock Purdy, C.J. Stroud, Bo Nix, Marcus Mariota, Justin Herbert, Baker Mayfield. These are some of the most common searches for fantasy football lineups in Week 16.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player name. In the second box, search for the second player name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed that our 'Who Should I Start?' tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, stats, projections, strength of schedule, players news, and enhanced search results with data to compare with a slick new interface. We hope you enjoy!
How It Works. Each week our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do, is to select the scoring format. There are three small radio buttons (small circle), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 16 Searches. Curious to see some tough lineup decisions for Week 16 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 16 Searches - Start/Sit Player Comparisons
Below are some popular searches and comparisons from our Who To Start tool for Week 16 for Gardner Minshew, Kirk Cousins, Jared Goff, Jaxson Dart, Brock Purdy, C.J. Stroud, Bo Nix, Marcus Mariota, Justin Herbert, Baker Mayfield:
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