X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

#1 Expert Projections
Save 50% Now
Import Your Leagues
Props Tool
Compare Any Players
Compare Any Players
24x7 News and Alerts

DraftKings Daily Fantasy Baseball Picks (9/22/19): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on September 22nd, 2019. Austyn Varney's MLB DFS analysis and sleepers for building optimal DFS rosters.

Welcome to Sunday baseball! The NFL is kicking off at 1 PM today, but so is baseball! DraftKings is still giving us big tournaments and the edge remains with a ton of fresh money on the sites. You have options no matter your price point, and the prize pools are all still huge. This is a fun slate. Runs will be scored and plenty of pitchers will have solid outings.

We'll be looking for the best play at each position. I'll be putting together a value article as well, so make sure to check that out as well. Let's dive in and find a top play at each position.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 9/22/19. The lineup picks will range from some of the elite players to mid-priced options and value plays. Be sure to also check out all the MLB Rosters for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. .

Featured Promo! Save 50% on any PGA Premium Pass using discount code MASTERS, this week only! Win more with our DFS and Betting Packages, get expert tools and advice from proven winners including the Lineup Optimizer, Research Station, betting/props cheat sheet and more. GAIN FULL ACCESS HERE

 

DraftKings DFS Starting Pitchers

Yu Darvish - CHC vs. STL - $11,600

The Cubs are in dire need of a win at this point and it will be on the shoulders of Yu Darvish. He’s been playing the best baseball of his Cubs career, striking out 14 and 13 in back to back games. He now gets a Cardinals team that’s middle of the road against righties and strikeout 22% of the time. It looks like Verlander will be the chalk on this slate, and while he’s a bit safer than Darvish, I don’t think the Astros will stretch him all the way out at this point. Darvish will go over 100 pitches if pitching well and Madden will get all he can out of Darvish after the bullpen has blown it back to back nights.

Reynaldo Lopez - CWS @ DET - $7,400

Reynaldo Lopez is extremely unreliable and up and down, but this is the best match-up he can possibly have and if there’s ever a time for his ceiling to poke through it’s here. The Tigers rank dead last in baseball against righties with a team .280 wOBA and 25% strikeout rate. We’ve seen Lopez go for seven innings and strikeout 10 before, so it really just comes down to whether or not he can locate his pitches. We’re hoping for five or six dominant innings, but there is upside for a lot more.

 

DraftKings DFS Infielders

C - Tom Murphy - SEA @ BAL (Means) - $4,200

When the Mariners face off with a lefty, Tom Murphy brings a big bat to the lineup. He’s sported a .400+ wOBA against southpaws on the season and is averaging nearly a home run every 12 at-bats. The Mariners face off with John Means today, who’s given up a .336 wOBA to opposing right-handers. There’s a reason Murphy is priced up. He’s proven himself as a real threat when in the lineup against a lefty.

1B - Freddie Freeman - ATL vs. SF (Webb) - $4,700

With the Braves holding an expected run total of six, Vegas obviously expects Logan Webb to struggle on the road here. He’s had trouble with both sides of the plate on the season, giving up a combined .368 wOBA. Freeman is the heart of this Braves lineup and he’ll be involved in at least a couple of those runs one way or another. Against righties, his wOBA remains over .380. Logan Webb has looked reverse splits a bit, but the 25 inning sample size is nowhere near enough to judge that.

2B - Whit Merrifield - KC @ MIN (Perez) - $4,300

Whit Merrifield flies under the radar on most slates as the Royals really aren’t too exciting of an offense. They face off with Martin Pérez today, who’s always had some HR Issues with righties. He’s only getting worse and worse at this point and his combined wOBA is up to .341. The Royals are a team I like today that will go completely un-owned. I’m a believer that if Martin Pérez these guys can hit a ton of home runs. Whit, Soler, and Dozier are a great mini stack on all sites.

Renato Nunez - BAL vs. SEA (Gonzalez) - $3,900

Marco Gonzales is already a bit shaky with the long ball, and now he moves to Camden Yards. Renato Nunez is back in the lineup and he’s been a lefty masher all year long. He’s fallen off a bit of late, but is still sporting a .339 wOBA against lefties with double digit home runs. The Orioles can put up a ton of runs, and they’re very rarely popular. This is another slate where you can get a low-owned Orioles stack in Camden Yards at an affordable price.

Alex Bregman - HOU vs. LAA (Rodriguez) - $5,400

Jose Rodriguez will get around 50 pitches before Jose Suarez takes over in this one. It’s really all semantics against this offense who’s going to rough up whoever is on the mound. If you’d like to know, Rodriguez is actually pretty good, but he’s also been very lucky. Jose Suarez on the other hand, has been one of the worst pitchers in all of baseball against opposing righties. They’re all pretty expensive on DraftKings, but rightfully so. Vegas expects another six plus runs and you know generally where the production is coming from. Bregman has been great against both sides of the plate, posting a .382 wOBA on the season with 38 home runs and a 13% strikeout rate. Bregman is safe with a ton of upside.

 

DraftKings DFS Outfielders

Giancarlo Stanton - NYY vs. TOR (Tepera) - $4,000

Stanton has been good since returning from injury, and he’s still too cheap. Make sure he’s in there as this is a day game, but he should be after homering last night. Ryan Tepera isn’t very good himself and the bullpen will follow after just a few innings. It’s always tough to predict bullpen games, but it’s clear to me that I’d rather have Stanton than any Blue Jays bullpen arm and I’m willing to take my chances that he connects on one at that price on DK.

Jason Heyward - CHC vs. STL (Mikolas) - $3,900

Jason Heyward is too cheap on DraftKings for a guy that should be leading off. Mikolas has struggled with lefties all season long and the Cubs have hit him around a few times themselves. Heyward has sported a .356 wOBA against righties and he’s only gotten better as the year has aged. I don’t love this entire game for offense, but I don’t mind taking a flier on a cheap Jason Heyward.

Things change quickly as lineups come out. If you have any questions, hit me up on Twitter @VarneyDFS and I'd be more than happy to help.

MLB DFS News and Injury Alerts




POPULAR FANTASY TOOLS

#1 Expert Projections
Save 50% Now
Import Your Leagues
Props Tool
Compare Any Players
Compare Any Players
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Wyatt Langford

Expected to be Activated on Saturday
Garrett Crochet

Goes on Injured List With Shoulder Inflammation
CFB

Jameson Williams Files Lawsuit Against NCAA, SEC, Big Ten
Junior Caminero

Back in Wednesday's Lineup After Injury Scare
Harry Hall

Volatility Continues at Cadillac Championship
Tommy Fleetwood

Looks to Rebound at Trump National Doral
Pierceson Coody

a Risky Value Play at Cadillac Championship
Deebo Samuel Sr.

Will Deebo Samuel Sr. Find a New Team Before Training Camps Open?
Jalen Johnson

Collects Second Playoff Double-Double
Akshay Bhatia

Offers Upside with Risk at Cadillac Championship
Elic Ayomanor

Dynasty Stock Way Down After NFL Draft
Jalen Brunson

Pours 39 Points on Hawks in Game 5
Darius Slayton

Dynasty Value Fading After Busy Giants Offseason
Jaylen Brown

Struggles From the Field in Game 5
Jayson Tatum

Picks Up Another Double-Double
David Njoku

With the NFL Draft Over, David Njoku Could Soon Find a Team
Tyrese Maxey

Records Double-Double With Rebounds
Tyler Warren

a Major Offseason Winner
Joel Embiid

Tallies 33 Points as 76ers Stave Off Elimination
Victor Wembanyama

Posts Second Straight Double-Double
Connor McDavid

Extends Multi-Point Streak Tuesday
Justin Thomas

a Scary Proposition at Cadillac Championship
Nikolaj Ehlers

Hurricanes Hope to Have Nikolaj Ehlers Back for Second Round
Alexander Nikishin

Could Be Available in Round 2
Victor Hedman

Logs Full Practice
Scottie Scheffler

The Leading Favorite at Cadillac Championship
Noah Ostlund

Likely to Miss Time Due to Lower-Body Injury
Arttu Hyry

Unlikely to Play Thursday
Collin Morikawa

Still a Smash Play at Cadillac Championship
Jonas Brodin

Spotted Using Crutches After Game 5
Viktor Hovland

Showed at Augusta He Can Finish Well
Sepp Straka

Attempting to Finish Better in Miami
PGA

J.J Spaun Enduring Roller Coaster Start to 2026
Min Woo Lee

Seeks to Make Adjustments at Cadillac Championship
Max Homa

May Struggle at Old Doral This Weekend
Ben Griffin

Rebounds From Rough Stretch as Miami Looms
Shane Lowry

Searching For Answers at Cadillac Championship
Russell Wilson

Jets Host Russell Wilson for a Visit, Considering him as Backup Option
Russell Henley

Daunting Test at Doral Likely Not a Place For Russell Henley
Jonathon Brooks

Fully Cleared for Offseason Program
Christian Gonzalez

Patriots Exercise Christian Gonzalez's Fifth-Year Option
Tyler Allgeier

One of the Biggest Losers After NFL Draft
A.J. Brown

Eagles to Receive a First-Round Pick if They Trade A.J. Brown?
Justin Rose

Returns to Action After Finishing Third at Masters Tournament
Hideki Matsuyama

Has The Approach Game to Win at Cadillac Championship
Si Woo Kim

Rolling Back Into Form For Cadillac Championship
Nicolai Hojgaard

Struggling to Find Consistency
Harris English

In Excellent Form Heading to Cadillac Championship
Corey Conners

Continues Playing Well Heading to Cadillac Championship
Aaron Rodgers

Steelers Place Right-of-First-Refusal Tender on Aaron Rodgers
Jauan Jennings

Visiting With Vikings
Quentin Johnston

Chargers Exercise Fifth-Year Option on Quentin Johnston
Jahmyr Gibbs

Lions Picking Up Jahmyr Gibbs' Fifth-Year Option
Bo Nix

Undergoes Cleanup Procedure on his Ankle
Junior Caminero

Suffers Jaw Contusion on Tuesday, Considered Day-to-Day
Scottie Barnes

Leading Raptors' Comeback Effort in Round 1
Pete Fairbanks

Going on Injured List With Nerve Irritation
Tobias Harris

a Bright Spot for Pistons in Tough Series
Jalen Duren

Struggling in First-Round Matchup
Austin Reaves

Officially Listed as Questionable for Game 5
Kevin Durant

Officially Out Wednesday
Collin Gillespie

Wants to Stick With Suns
Jonathan Isaac

Expected to Remain Out Wednesday
Kevin Huerter

Iffy for Wednesday Night
Franz Wagner

Considered Questionable for Game 5
Austin Reaves

on Track to Return Wednesday
Spencer Strider

to Make Season Debut This Weekend
Kevin Durant

Unlikely to Play Wednesday
Joel Embiid

Cleared for Game 5
Roope Hintz

Likely to Miss Entire First-Round Series
Jason Zucker

Good to Go for Game 5
Josh Norris

Won't Play Tuesday
Colton Dach

Available Tuesday
Connor Ingram

Returns to Oilers Net for Game 5
Luis Robert Jr.

Out on Tuesday With Back Tightness
Jason Dickinson

Considered a Game-Time Decision for Tuesday's Action
Connor McDavid

a Game-Time Call Tuesday
Juan Soto

Dealing With Forearm Tightness, Serving as DH on Tuesday
Isaiah Likely

Remains Well-Positioned for Mid-Career Breakout Following NFL Draft
Jauan Jennings

' Dynasty Value Fading Following NFL Draft?
Luther Burden III

Poised for Breakout Season in Chicago?
CFB

Brendan Sorsby Facing Potential Permanent Loss of Eligibility
MarShawn Lloyd

Is MarShawn Lloyd a Dynasty Buy-Low Candidate Following NFL Draft?
Emanuel Wilson

Dynasty Value Fading After Seahawks' Draft Addition
Jalen Nailor

Remains Poised for Prominent Role in Las Vegas Following NFL Draft
Manny Machado

Departs Early With Undisclosed Injury on Monday
Philadelphia Phillies

Phillies Fire Manager Rob Thomson
Elmer Rodríguez

Yankees to Promote Top Pitching Prospect Elmer Rodriguez
Pete Fairbanks

Pulled on Monday With "Unusual Sensation" in his Thumb
Mikhail Sergachev

Has Three Assists in Overtime Loss
Brett Howden

Records Three Points in Vital Win
Rasmus Ristolainen

Registers Two Assists in Game 5 Loss
Arturs Silovs

Helps Penguins Survive for Second Time
Sidney Crosby

Delivers Two Assists in Elimination-Game Win
NAS

Predators Pick Up KHL Standout Vitali Pinchuk
Paolo Banchero

Efficiency Woes Continue in Game 4
Julius Randle

Leads Timberwolves With 27 Points Monday
Giancarlo Stanton

Heading to Injured List With Calf Strain
Travis Bazzana

Guardians Calling Up Former First Overall Pick Travis Bazzana
Will Smith

Back in Action in Series Opener Against Marlins
Josh Naylor

Back in Starting Lineup on Monday
Jason Zucker

Probable for Game 5 Against Bruins
Carson Hocevar

Scores his First Career NASCAR Cup Series Victory at Talladega
Chris Buescher

Misses out on Winning at Talladega by Finishing Second
Alex Bowman

Earns First Top-Five Finish at Talladega Since Returning From Injury
Chase Elliott

Scores A Fourth-Place Finish at Talladega
Zane Smith

Nabs First Top-Five Finish of the 2026 Season at Talladega
CFB

Texas Tech Quarterback Brendan Sorsby Enters Rehab
Youssef Zalal

Suffers Unanimous-Decision Loss
Aljamain Sterling

Wins Back-To-Back Fights
Norma Dumont

Drops Decision At UFC Vegas 116
Joselyne Edwards

Scores Upset Win
Alexander Hernandez

Gets Dominated
Alexander Hernandez

Rafa Garcia Dominates Alexander Hernandez
Adrian Luna Martinetti

Unsuccessful In His UFC Debut
Davey Grant

Gets Back In The Win Column
Manny Machado

Clubs Two Homers, Starting to Turn Things Around?
Logan O'Hoppe

Placed on 10-Day Injured List Due to Left-Wrist Fracture
Denny Hamlin

Is Denny Hamlin Worth Rostering for Talladega?
NASCAR

Is Bubba Wallace Playable in Talladega DFS Lineups?
Josh Naylor

Absent on Sunday With Quad Tightness
Ryan Helsley

Returns From Bereavement List on Sunday
Steven Kwan

Back in Sunday's Lineup
Tyler Reddick

Stay Away From Tyler Reddick at Talladega
Ryan Blaney

Can Ryan Blaney Shake Off The Bad Luck at Talladega?
Austin Cindric

Could Contend For Another Talladega Win
Kyle Busch

an Easy DFS Pick at Talladega
Ricky Stenhouse Jr

. a High-Risk, High-Reward Pick at Talladega
Todd Gilliland

a Sleeper to Watch at Talladega
Brad Keselowski

Is Brad Keselowski Worth Rostering for Talladega Lineups?
Chase Briscoe

Could Chase Briscoe be A Sneaky Tournament Play for Talladega Lineups?
Christopher Bell

Should DFS Managers Trust Christopher Bell at Talladega?
Ty Gibbs

Is A DFS Risk for Talladega Lineups
Youssef Zalal

Set For UFC Vegas 116 Main Event
Aljamain Sterling

An Underdog At UFC Vegas 116
Joselyne Edwards

Set For UFC Vegas 116 Co-Main Event
Norma Dumont

Looks To Extend Her Win Streak
Alexander Hernandez

A Favorite At UFC Vegas 116
Rafa Garcia

Looks For His Third Consecutive Win
Adrian Luna Martinetti

Set For His UFC Debut
Davey Grant

Looks To Get Back In The Win Column
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF