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See RotoBaller at the top of Google

Oct 16, 2026, 4:08 PM ET

Kansas City Chiefs quarterback Patrick Mahomes will take on the Los Angeles Chargers at home in Week 6. Mahomes was listed on the injury report with a knee injury again, but it's the same knee he's been managing all season, so there's no reason to worry. The Chiefs superstar should be well-rested and prepared to face the Chargers at Arrowhead fresh off of the team's bye week. The Chargers have been dreadful this year, starting the season 0-5, and Mahomes should be able to take advantage of the matchup. The turnover-prone Los Angeles offense should also give the veteran QB good field position to start drives. Mahomes will be without wide receiver Rashee Rice in this contest, but he should still have enough playmakers to easily win this contest. Mahomes is ranked QB8 in our RotoBaller Week 6 rankings, making him a strong QB1 at home following the bye week. Fantasy managers should have no issues plugging Mahomes right back into lineups this Sunday.--Joshua Costello
Source: Chiefs.com
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Oct 16, 2026, 3:57 PM ET

Pittsburgh Steelers quarterback Aaron Rodgers has thrown three touchdown passes in three straight games and will look to maintain that streak in Week 6 against the Tampa Bay Buccaneers. Tampa Bay has been solid defensively so far this season, holding opposing quarterbacks to the ninth-fewest fantasy points per contest. The Buccaneers are also one of just seven teams allowing fewer than 300 yards of offense per game through five weeks. Given the difficult matchup and the fact that Pittsburgh is thin at wide receiver, with Michael Pittman Jr. (foot), Roman Wilson (finger), and Ben Skowronek (calf) all inactive, Rodgers isn't necessarily set up for success in this one. Nonetheless, Tampa Bay has been significantly tougher against the run, so it would not be surprising to see Rodgers attempt 35-plus passes for the fourth time this year. The health of DK Metcalf (illness) will be worth monitoring heading into Sunday, but assuming he plays, Rodgers should be viewed as a viable streaming option and high-end QB2 in Week 6.--Jorden Hill
Source: RotoBaller
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Oct 16, 2026, 3:05 PM ET

Chicago Bears quarterback Caleb Williams (hamstring) practiced in full Friday but is listed as questionable for Sunday's Week 6 matchup against the Atlanta Falcons, according to Brad Biggs. Williams has missed three consecutive games since suffering a right hamstring injury against Minnesota in Week 2. He was also listed as a full participant Wednesday and Thursday, although Wednesday's session was a walkthrough. Williams revealed Thursday that he suffered a hamstring tear and still needed to complete additional medical testing before receiving clearance to play. Through his first two games, he threw for 407 yards and two touchdowns while rushing for 107 yards and two more scores. His rushing ability has been an important part of his fantasy production, making his recovery particularly relevant for managers considering starting him. The full practices are encouraging, but his availability remains uncertain until the Bears make a final decision.--Bruno Mulé
Source: Brad Biggs
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Oct 16, 2026, 3:01 PM ET

Tampa Bay Buccaneers quarterback Jalon Daniels will remain the starter for at least one more week. The Bucs were hopeful that Baker Mayfield (thumb) would be ready, but he'll miss at least one more game because of his dislocated thumb. Daniels was surprisingly efficient during last Thursday's win over the Dallas Cowboys. He completed 19-of-25 passing attempts for 189 yards with one touchdown and zero interceptions. He also rushed the ball seven times for an additional 23 yards on the ground. The Bucs will likely continue to use a run-first offense, which will limit Daniels' overall upside. Fantasy managers should consider Daniels a low-end QB2 in superflex formats for the Week 6 matchup against the Pittsburgh Steelers.--Andy Webb
Source: Pro Football Reference
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Oct 16, 2026, 1:48 PM ET

Baltimore Ravens quarterback Lamar Jackson (ankle) will miss his second straight game after head coach Jesse Minter announced on Friday that he has been ruled out for Sunday's divisional matchup with the Browns. Veteran Tyler Huntley will start again after leading the team to an overtime victory over the Falcons in Week 5 and keeping the offense largely on track, as he's been known to do in his time as Jackson's backup. While the fantasy ceilings of running back Derrick Henry and Zay Flowers are ultimately lowered without Jackson under center, Baltimore's Plan B is better than most, and both can still be started with only slightly tempered expectations.--Patrick McGrath
Source: Jamison Hensley
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Oct 16, 2026, 1:38 PM ET

Atlanta Falcons quarterback Michael Penix Jr. (ribs) is off the injury report and set to start the team's Week 6 matchup with the Bears, according to NFL Insider Ian Rapoport. After being knocked out of the Falcons' Week 5 overtime loss to the Ravens with a rib injury, Penix has logged a full week of practice participation and carries no injury designation into Sunday. Since returning in Week 3 from the knee injury that ended his 2025 season, Penix has been the fantasy QB20 while notably elevating the ceilings of Bijan Robinson, Drake London, and tight end Kyle Pitts Sr. In a Bears matchup with one of the week's highest over/unders, all of Atlanta's usual playmakers can be started with confidence, though Penix himself is RotoBaller's QB25.--Patrick McGrath
Source: Ian Rapoport
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Oct 16, 2026, 12:30 PM ET

Baltimore Ravens quarterback Lamar Jackson (ankle) is not present during the media-viewing portion of Friday's practice, which indicates that backup Tyler Huntley will likely start for the second straight week this Sunday against the division-rival Cleveland Browns, according to Jamison Hensley of ESPN. Jackson missed every practice this week and has not suited up since spraining his left ankle in the Week 4 win over the Tennessee Titans. Huntley has won his last three starts as a fill-in starter for Jackson, so they definitely are not going to rush Jackson back if he is not quite ready. In the three victories with Huntley under center, the Ravens have averaged 33.7 points. Huntley has become one of the better backups in the league, and he will once again be on the QB2 streaming radar in superflex fantasy leagues if he makes his second straight start. Fantasy managers should be ready to be without Jackson for a second straight week. If he is ruled out on Friday, his next chance to play will be at home for another divisional contest on Sunday, Oct. 25, against the Cincinnati Bengals.--Keith Hernandez
Source: ESPN.com - Jamison Hensley
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Oct 16, 2026, 11:27 AM ET

The Philadelphia Eagles are signing quarterback Joe Milton III off the Dallas Cowboys' practice squad, according to Jordan Schultz. Philadelphia is adding depth at the position with Jalen Hurts (calf) ruled out for Sunday's Week 6 matchup against the Carolina Panthers due to a superficial blood clot. Tanner McKee is expected to start in Hurts' absence, with rookie Cole Payton also on the roster. Milton appeared in four games for Dallas in 2025, completing 15 of 24 passes for 183 yards, one touchdown and two interceptions while adding 50 rushing yards on five carries. The former sixth-round pick has made five NFL appearances across two seasons but has yet to start a regular-season game. With McKee expected to handle the starting duties, Milton does not figure to have an immediate fantasy role. His potential involvement beyond Week 6 will depend on Hurts' recovery and how Philadelphia handles its quarterback depth chart.--Bruno Mulé
Source: Ari Meirov
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Oct 16, 2026, 10:30 AM ET

New Orleans Saints quarterback Tyler Shough is becoming increasingly difficult to trust in standard fantasy lineups after two performances that bear little resemblance to his impressive start to 2026. His first three games produced 917 passing yards and eight touchdowns, numbers that briefly made him an appealing option for managers searching for quarterback help. That momentum has disappeared. Shough has thrown for 382 yards and one touchdown over his last two starts, with Sunday's 23-13 defeat against Minnesota representing his worst outing yet. He completed 16 of 25 passes for 96 yards and two interceptions as the Saints managed only 142 yards of total offense. New Orleans had few answers for Minnesota's defense, making it difficult to place the entire blame on its quarterback. Shough has also been dealing with a left-hand issue, although full practices Wednesday and Thursday suggest he remains on track to face the Giants in Week 6. His starting job keeps him relevant in Superflex formats. For managers in standard one-quarterback leagues, Sunday's matchup offers a chance to evaluate whether his early-season passing production is something they can reasonably expect again.--Bruno Mulé
Source: RotoBaller
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Oct 16, 2026, 12:47 AM ET

Seattle Seahawks quarterback Sam Darnold completed 27 of 51 passes for 278 yards, no touchdowns, and two interceptions in Thursday's 17-14 loss to the Denver Broncos. He added 19 yards on two carries. Darnold was under duress all night, taking 17 hits and getting sacked five times. Thursday marked the second straight game Seattle allowed five sacks. It's a disappointing result for the veteran, as he couldn't get much going despite Denver missing its top corner, Patrick Surtain II (ankle). Darnold has now thrown two interceptions in three of his last four games, and his TD:INT ratio sits at an unsavory 7:5 through four full starts. Seattle will face the Kansas City Chiefs in a pivotal primetime Week 7 matchup.--Alex Ciulla
Source: ESPN
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Oct 16, 2026, 12:31 AM ET

Denver Broncos quarterback Bo Nix completed 17 of 27 passes for 107 yards, with no touchdowns, in his team's 17-14 win over the Seattle Seahawks on Thursday Night Football. He added two rushing yards on four attempts. Nix and the Broncos staked a 14-3 lead in the second quarter of Week 6, though they wouldn't score again until the extra frame in what was a stiff test for both offenses. Either way, it was another subpar performance from the former twelfth-overall pick, who has now failed to eclipse a 65% completion rate in all but one appearance. Better days are ahead for Nix and the Broncos' attack, but fantasy managers relying on him may want to look elsewhere for help, particularly when the 26-year-old faces a tough opponent. Nix will get a much softer Week 7 matchup on the road against the Cardinals.--Alex Ciulla
Source: ESPN
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Oct 15, 2026, 7:49 PM ET

Dr. Ryan Schreiter, who is a clinical orthopaedic and sports medicine physician at Temple University, expects a 45-day to three-month recovery period for Philadelphia Eagles quarterback Jalen Hurts' (calf) superficial blood clot, according to Sports Radio 94 WIP. The Eagles announced on Thursday that Hurts will not play in Week 6 against the Carolina Panthers on Sunday after a recent ultrasound revealed the blood clot in Hurts' leg. The 28-year-old is now out indefinitely, and from what Schreiter thinks, this medical issue could keep Hurts out for the rest of the 2026 season. For now, backup Tanner McKee will take over an Eagles offense that could also be without star running back Saquon Barkley (hamstring) for the second straight game. Fantasy managers should not outright drop Hurts just yet until we have confirmation from the Eagles that this could be a season-ender. Philly is now starting down a potential four-game losing streak if they come up short against the Panthers, and Hurts' injury could torpedo their entire season. Stay tuned for more information regarding a more concrete timetable for Hurts. If he is out for multiple months, the Eagles could look to re-sign veteran QB Andy Dalton or search for another available veteran signal-caller.--Keith Hernandez
Source: Sports Radio 94 WIP
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Oct 15, 2026, 5:40 PM ET

Baltimore Ravens quarterback Lamar Jackson (ankle) is not practicing for the second straight day on Thursday, according to ESPN's Jamison Hensley. The Ravens were saying earlier this week that there was a realistic chance that Jackson could return this weekend to face the division-rival Cleveland Browns in Week 6 after tweaking his ankle in the Week 4 win over the Tennessee Titans, which caused him to sit out the Sunday night overtime victory over the hosting Atlanta Falcons. The 29-year-old missing two straight practices this week does not exactly make him look like he is ready to return this weekend, so fantasy managers should be planning to be without Jackson again as things currently stand. The Ravens have the utmost confidence in Huntley, who is very similar in many regards to Jackson as a QB. Head coach Jesse Minter said last week that Jackson is the kind of player who could miss practice all week and still play, but it seems foolish for the Ravens to put the former MVP in harm's way like that. Jackson will probably have to practice on Friday to have a chance at suiting up in Week 6.--Keith Hernandez
Source: ESPN.com - Jamison Hensley
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Oct 15, 2026, 4:18 PM ET

Chicago Bears quarterback Caleb Williams (hamstring) said he had a tear in his injured hamstring and that he is still uncertain whether he will be able to return for his team's Week 6 matchup against the Atlanta Falcons, per Sean Hammond of the Chicago Tribune. Williams has been sidelined since suffering a hamstring injury late in Chicago's Week 2 loss to the Minnesota Vikings. The 24-year-old had a monster game in his lone fully healthy outing of the season in Week 1 against the Carolina Panthers, throwing for 269 yards and two touchdowns while also rushing for 65 yards and two scores. However, he may not be operating at full strength even if he is able to play in Week 6. If Williams remains sidelined, Chicago could turn to either Tyson Bagent or Case Keenum to take over under center against Atlanta.--Will Brady
Source: Chicago Tribune - Sean Hammond
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Oct 15, 2026, 3:47 PM ET

Chicago Bears quarterback Caleb Williams (hamstring) was a full participant in Thursday's practice, according to Sean Hammond of the Chicago Tribune, providing another encouraging sign that a Week 6 return is approaching. Williams was also listed as a full participant Wednesday, although that was only an estimate because Chicago held a walkthrough. Thursday's session marked a more meaningful step for the 24-year-old, who has missed three consecutive games since injuring his hamstring against Minnesota in Week 2. Through two appearances this season, Williams completed 36 of 55 passes for 407 yards, two touchdowns and one interception while adding 107 rushing yards and two scores on 15 carries. His mobility accounted for a significant portion of his early fantasy production, making his ability to run effectively an important consideration whenever he returns. Head coach Ben Johnson has yet to officially name his starting quarterback for Sunday's matchup against the Atlanta Falcons, but Williams' continued progress puts him in a strong position to reclaim the job. Fantasy managers should monitor Friday's injury report for further confirmation of his availability.--Bruno Mulé
Source: Sean Hammond
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