X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

DraftKings Daily Fantasy Football Picks (Week 6): NFL DFS Lineups

The top daily fantasy football lineup picks for DraftKings in Week 6. Ben Rolfe's NFL DFS analysis and sleepers for building optimal DFS rosters.

Week 5 did not really offer many surprises in terms of the overall picture of teams. We learned a few little lessons, such as the Atlanta Falcons offense is just flat-out bad on the road and we never know which Buffalo Bills team is going to show up. Entering Week 6, we, unfortunately, lose two of the most exciting offenses, in the Kansas City Chiefs and New England Patriots, from this slate. The good news is the Jacksonville Jaguars defense are playing the Dallas Cowboys and we were not really relying on Cowboys players anyway. This week the Falcons lottery falls with the Tampa Bay Buccaneers so do not be surprised to find a number of their offensive weapons below.  Below are my DraftKings DFS Lineup Picks for Week 6.

These DraftKings lineup recommendations are based on matchups, early week performances, overall upside/talent levels, opportunity, and other factors such as Vegas odds, home field advantage, and more. There are quite a few great value plays available, so read on to find out which players are the best for Week 6.

Good luck with your DraftKings DFS lineups!

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 6 Picks

Matt Ryan - ATL vs. TB (DK $6,800)

He might be the highest priced player at the position on the slate, but there is every reason to believe Ryan will be worth it. His down week against the Steelers proved that we still cannot trust him on the road even against a bad defense. This week he returns home to face yet another bad defense in the Buccaneers. In his three home games this season, Ryan is averaging 355 passing yards and 3.33 passing touchdowns per game. His current completion rate at home is 76.5% and he has a quarterback rating of 137.9. In addition, his offensive line is allowing just two sacks per game at home compared to five per game on the road. This game is likely to be a shootout with the over/under set at 57.5 in most places, the second highest line of the week. The final point is that this is a must-win game for the Falcons or they will slip to 1-5, which is virtually unrecoverable.

Jameis Winston - TB @ ATL (DK $5,800)

The Falcons defense ranks fourth against the quarterback heading into this week and actually, that number is a little misleading. The only reason they are not higher is due to their good performance against Nick Foles when they had their defense intact in Week 1. The group is completely decimated and they look a mess, unable to tackle and losing assignments. In contrast, the Buccaneers pass catchers have been on fire this year and they are coming off a bye week, giving them seven extra days to prepare to face this defense. Winston looked ugly in his first outing against the Bears, but there are extenuating circumstances. Firstly, he came in with his team chasing the game and needing to force things. Secondly, he had been away from the team three weeks and had to share practice snaps leading into Week 4. Finally, he was facing one of the best defenses in football this year, in their backyard, with the crowd right behind the team. Now he gets to face one of the worst defenses in football having had two weeks of taking starters snaps. If he doesn't perform in this game then he probably doesn't even deserve to be a starter in the NFL again.

 

DraftKings DFS Running Backs - Week 6 Picks

Todd Gurley - LAR @ DEN (DK $10,100)

I do not know how I cannot pick this guy. Yes, you are going to have to be clever with your lineup to fit him in but his production has been worth it. Through five games he has nine total touchdowns and two three-touchdown games. He is averaging 20.2 rushes and 3.8 receptions per game and a combined 129 yards per game. In addition, the Rams are going into Denver for this game, a team that currently ranks eighth-worst against running backs, with some questions marks. Brandin Cooks and Cooper Kupp left the game against Seattle with concussions and although both are expected to play Sunday I still think they might be eased back in. The other question mark is the weather in Denver this weekend. The high on Sunday is currently expected to be 28 and by game time it is likely to be slightly lower. In addition, there is a good chance this might be the first snow game of the year. That sounds like perfect conditions for a slugfest game, which features a lot of running. Exactly the type of game you pay Todd Gurley to win you.

Jordan Howard - CHI @ MIA (DK $6,500)

Howard has been disappointing this year but I think this is his bounce-back game on Sunday. The Dolphins rank fifth against running backs this season and have given up over 15 fantasy points to lead running backs each of the last two weeks. The most damming stat for me is that Joe Mixon carried the ball 22 times last week despite the Bengals trailing the entire game until the fourth quarter. Mixon's style is fairly close to Howard's and I can see the Bears utilizing Howard early in this game and then again in the second half to put the game away. This one is the pick I feel most uncertain about, because of the presence of Tarik Cohen, but the running back position is lacking depth and Howard's price here feels like a good deal to me.

Chris Carson - SEA @ OAK (DK $4,400)

Ah, the London games, where weird stuff always seems to happen. It always feels like one team does not turn up for these games and if I have to pick between Jon Gruden or Pete Carroll having his team ready then I will go Carroll all day long. The Raiders rank eighth-worst against running back, surrendering on average over 100 yards and a touchdown per game. Carson for his part has rushed for over 100-yards in each of his last two games. The only question mark is around touches, as he appears in a time-share with Mike Davis. However, at this price, it is hard to pass up a runner as dynamic as Carson facing a defense as poor as the Raiders.

 

DraftKings DFS Wide Receivers - Week 6 Picks

Mohamed Sanu - ATL vs. TB (DK $4,800)

If I am getting Gurley in my lineup, I need to save money and for that reason, I will target Sanu as the pass catcher in Atlanta to own this week. I expect Julio Jones to also have a big day, and a bounce back after last week but he is a lot more expensive. Sanu has now seen 23 targets the last three weeks, having touchdowns in two of the games and over 100-receiving yards in the other. This game is going to be another shootout, where the total likely gets into the mid-60s and the Buccaneers rank second worst against wide receivers for fantasy points this season.

DeSean Jackson - TB @ ATL (DK $5,900)

Jackson is having a monster year so far. At some point, regression is likely, given he is averaging 24.9 yards per reception and has a catch rate 12% higher than at any other time in his career, but I do not think it will be this week. The Falcons defense is ranked fifth against wide receivers this season, and I explained above why that should be higher. Jackson has been having his success against deep balls and we have seen evidence of the Falcons inexperienced safeties struggling in this regard, with John Ross' long touchdown being a prime example. Jackson may only have five receptions at a maximum this week but I think close to 100-yards and a touchdown is more than possible. Plus at this price, he is too good to pass up in a potential shootout.

Tyler Boyd - CIN vs. PIT (DK $6,000)

Boyd is coming off a down week against the Dolphins last week. To be fair the whole offense seemed to struggle against the Dolphins, who rank seventh best against wide receivers in fantasy. Last week we saw the Falcons play the Steelers and Jones was effectively eliminated by the coverage of Joe Haden. There is a good chance that we could see Haden go toe-to-toe with A.J. Green this week and if so Dalton will need to look elsewhere. When that has been the case he has gone to Boyd, who has two 100-yard receiving games and two touchdowns so far this season. As a unit the Steelers pass defense ranks fourth against receivers and the Bengals offensive line should keep Dalton clean for him to find Boyd plenty of times this week.

 

DraftKings DFS Tight Ends - Week 6 Picks

Austin Hooper - ATL vs. TB (DK $3,500)

Last week Hooper faced the second-worst defense against tight ends and this week he gets to face the worst. Hooper set season highs in targets (11), receptions (9) and yards (77) in Week 5. This week I think he can get close to those numbers again and possibly even add a touchdown as well. I expect the Falcons offense to have a lot more success this week and while Hooper might not get the same number of targets there is a good chance he sees more near or in the red zone. These two weeks may be the only time this season that it is not strictly about touchdowns for Hooper.

Antonio Gates - LAC @ CLE (DK $2,800)

Again this is thinking about how to work Gurley into a lineup. Gates is not having a great year, averaging just 21.4 yards per game and has one touchdown on the season. However, this will probably be the best pass rush the Chargers have faced and Rivers will need to get the ball out. The Browns have not been terrible against tight ends (14th worst) this season but they have not faced anyone of great reputation. The best they have faced is Jared Cook who has 110 yards and two touchdowns and Jesse James who had 60-yards on three receptions. Those numbers demonstrate that Gates can have a good day and is a player I think has a high ceiling for a bargain basement price this week.

 

DraftKings DFS Defenses - Week 5 Picks

Chicago Bears @ Miami Dolphins (DK $3,300)

The Dolphins are the third worst team against fantasy defenses in terms of average fantasy points scored by the defense. The Chicago Bears are arguably the best defense in the NFL this season. The Bengals had two defensive touchdowns last week and they are perhaps the only team the Dolphins have faced who have a comparable defensive line to the Bears. I expect Khalil Mack to have a big day in this one.

Indianapolis Colts @ New York Jets (DK $2,500)

The Jets rank 11th against fantasy defenses and despite their big week last week I think the Colts can have success. The Colts are not doing anything special but they have been having success. Before I lock this pick in on Sunday I will make sure to check the Colts inactives. If they are riddled with injuries, I might look elsewhere. However, if they have a decent unit then they are ultimately facing a rookie quarterback, and had a decent amount of success against the Patriots run game last week.

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Rui Hachimura

Available After Two-Game Absence
Tyrese Maxey

Has Chance to Play Saturday
Jahmai Mashack

Remains Out Friday
Jaden McDaniels

Not Playing Saturday
De'Anthony Melton

Won't Play Friday Night
Anthony Edwards

Remains Sidelined Saturday
Rob Dillingham

is Available to Play on Friday
Luka Dončić

Luka Doncic Ready to Rock Friday
Isaac Okoro

to Suit up on Friday
Jaime Jaquez Jr.

Available Against Cavaliers
Guerschon Yabusele

is Available to Play
Jarrett Allen

to Play Limited Minutes Friday
Nick Richards

Won't Play on Friday
Jock Landale

is Ruled Out for Friday
Nnamdi Madubuike

Optimism That Nnamdi Madubuike Will Return From Neck Injury
Dylan Garand

Starts Friday
Aaron Nesmith

to Play on Friday
Obi Toppin

is Cleared for Friday's Game
Noah Ostlund

Won't Play Friday
Jordan Miller

is Available on Friday
Connor Zary

Returns to Practice
Samuel Honzek

Won't Return This Season
Damon Severson

Labeled Week-to-Week
Sam Steel

Leaves Road Trip Due to Injury
Mikko Rantanen

Could Return Saturday
NFL

Jordyn Tyson to Hold A Workout for Teams in April
New York Jets

Jets Unlikely to Draft Ty Simpson in the First Round?
Shane Baz

Orioles Agree to Five-Year Extension
Jeremy Peña

Jeremy Pena Making Season Debut on Friday Against Angels
Tiger Woods

Involved In Rollover Car Crash
Bhayshul Tuten

Remains a Clear Breakout Candidate Heading into 2026
NFL

Can Jonah Coleman Develop into a Starting NFL Running Back?
Rico Dowdle

Remains Likely to Split Carries in Pittsburgh
NFL

Can KC Concepcion Be a Dynamic Playmaker in the NFL?
Chet Holmgren

Won't Play on Friday
Rashid Shaheed

Is Rashid Shaheed Limited to a Downfield Role in Seattle?
Anfernee Simons

is Downgraded to Out
Marcus Mariota

Remains an Injury Away from Playing Time in Washington
Neemias Queta

is Upgraded to Available
Jaylen Brown

is Ruled Out on Friday
Najee Harris

to Meet With Raiders Next Thursday
Damar Hamlin

Bills Re-Sign Safety Damar Hamlin to One-Year Deal
Tanner Bibee

Shoulder Issue Not Considered Serious
NFL

Nicholas Singleton Relying on Traits Over Tape for Early Draft Capital
J.K. Dobbins

Positioned for Another Strong Season in Denver
NFL

Malachi Fields' Draft Stock Looks to Be Sliding
Barrett Hayton

Out Week-to-Week
Travis Etienne Jr.

Should See Feature Role Following Big-Market Deal
Tony DeAngelo

to Miss 1-2 Weeks
Sam Steel

Makes Early Exit Against Islanders
NFL

Ty Simpson Garnering First-Round Buzz
Damon Severson

Exits With Upper-Body Injury Thursday
Joe Pyfer

Set For UFC Seattle Main Event
Yaroslav Askarov

Suffers New Injury Blow
Israel Adesanya

Returns At UFC Seattle
Evan Rodrigues

Breaks Finger Thursday
Maycee Barber

Looks To Extend Her Win Streak To Eight
Sidney Crosby

Suffers Lower-Body Injury Thursday
Alexa Grasso

Looks To Get Back In The Win Column
Dominic Canzone

a Top Pickup After Two-Homer Game
Niko Price

In Dire Need Of Victory
Michael Chiesa

Set For Retirement Fight
Chase DeLauter

Launches Two Home Runs, Emerges as Top Waiver-Wire Target
Lerryan Douglas

Set For His UFC Debut
Julian Erosa

Looks To Bounce Back
Tanner Bibee

Leaves Opening Day Start Early With Shoulder Inflammation
Tyler Allgeier

Joins a Crowded Backfield in Arizona
Kenneth Gainwell

Can Kenneth Gainwell Maintain PPR Prowess in New Digs in Tampa?
Jakub Dobes

Defeats the Blue Jackets on Thursday
NFL

Zachariah Branch a Day 2 Receiver With Game-Changing Speed
Cade Otton

Quietly Due for a Bigger Workload?
Noah Cates

has Two-Point Game on Thursday
Tetairoa McMillan

Headed for a Big Year 2?
Cristopher Sánchez

Cristopher Sanchez Makes a Statement on Opening Day With 10 Strikeouts
Kevin McGonigle

has Four Hits in Impressive MLB Debut
Nico Hoerner

Cubs Agree to Six-Year Deal With Nico Hoerner
Jacob Misiorowski

Shows Off his High-Strikeout Upside in Opening Day Win
Marcus Foligno

Available Against Panthers
Tony DeAngelo

Unavailable Thursday
Anthony Mantha

Good to Go Thursday
Paul Skenes

Greeted Harshly by Mets on Opening Day
Thomas Chabot

Out 4-8 Weeks After Surgery
Robert Thomas

Sits Out Thursday's Action
Brandon Lowe

Hits Two Home Runs on Opening Day
Ketel Marte

Active, Leading Off on Opening Day
Kevin McGonigle

Batting Sixth in MLB Debut
Jeremy Peña

Jeremy Pena Not in the Lineup on Opening Day
JJ Wetherholt

Batting Leadoff in MLB Debut
Jackson Chourio

Placed on Injured List with Fractured Hand
Francisco Lindor

Officially Starting on Opening Day
Sean Murphy

Lands on 10-Day Injured List
Bryce Miller

Placed on 15-Day Injured List With Oblique Strain
Lars Nootbaar

Will Begin the Season on 60-Day Injured List
Ryan Fox

a High-Upside Value in Houston
Marco Penge

a Boom-or-Bust Option in Houston
Aaron Rai

Looks to Bounce Back in Houston
Jason Day

a Volatile Option at the Texas Children's Houston Open
Harris English

Eyes a Bounce-Back at the Texas Children's Houston Open
Ben Griffin

Looks for Turnaround at the Texas Children's Houston Open
Rickie Fowler

Brings Strong Form Into Texas Children's Houston Open
Ryan Gerard

Can Continue Rolling at Texas Children's Houston Open
Pierceson Coody

Bounces Back at Valspar Championship
Rasmus Hojgaard

Trying to Get Back on Track at Texas Children's Houston Open
Michael Thorbjornsen

Playing Well Heading to Texas Children's Houston Open
Harry Hall

Looking for Consistency at Texas Children's Houston Open
Brooks Koepka

Continues Building Momentum
Scottie Scheffler

Withdraws From Texas Children's Houston Open
Luke Clanton

Might Have a Problem in Houston
Sam Stevens

Happy to See Houston This Week
Keith Mitchell

Tries to Rebound After The Players Championship
Will Zalatoris

Returning This Week at Houston
Wyndham Clark

Trending in the Wrong Direction Heading to Houston
Shane Lowry

Seeking Better Luck in Houston This Weekend
Lerone Murphy

Suffers His First Loss
Movsar Evloev

Edges Out Lerone Murphy
CFB

Notre Dame Ranks No. 1 in Returning Production for 2026
Michael Aswell

Jr. Drops Decision At UFC London
Michael Aswell

Luke Riley Outclasses Michael Aswell Jr.
Sam Patterson

Suffers Unanimous-Decision Loss
Michael Page

Wins Lackluster Decision
Austen Lane

Suffers First-Round TKO Loss
Iwo Baraniewski

Delivers 28-Second TKO
Tyler Reddick

Overcomes Adversity for Fourth Victory of the Season At Darlington
Brad Keselowski

Falls Short of Darlington Victory Despite Domination
Ryan Blaney

Recovers From Pit-Road Struggles to Score Career-Best Darlington Finish
Carson Hocevar

Rallies to Finish Fourth at Darlington
Kyle Larson

Decent Performance Ends with Technical Issues At Darlington
Tyler Reddick

the Clear Favorite at Darlington
Kyle Larson

a High-Risk, High-Reward Driver at Darlington
Ryan Blaney

Is Getting Better at Darlington
NASCAR

Bubba Wallace Not Slowing Down at Darlington
Chris Buescher

Should be a Top-10 Contender at Darlington
Austin Cindric

a Sleeper at Darlington
Erik Jones

Quickest in Practice at Darlington
Denny Hamlin

Qualifies Ninth for this Week's Cup Race at Darlington
Chase Briscoe

Is One of the Top DFS Options of the Week for Darlington
William Byron

Is William Byron A Playable DFS Option for Darlington Lineups?
Christopher Bell

Could Christopher Bell be Considered A Decent DFS Option for Darlington?
Chase Elliott

Is Chase Elliott Worth Rostering At Darlington This Week For DFS?
Joey Logano

May Not Have the Speed to Warrant A Darlington DFS Lineup Spot
Ross Chastain

Should DFS Players Trust Ross Chastain at Darlington?
Kyle Busch

Could Kyle Busch Be A Worthy DFS Option for Darlington?
Brad Keselowski

May be A Contriarian DFS Tournament Option At Darlington
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF