NFL Week 7 Predictions: Picks and Analysis for Every Football Game

October 19, 2025

Free NFL betting picks for every Week 7 matchup in 2025. Expert analysis and predictions for NFL Week 7. Who should you bet in Week 7? Analysis for every game on the slate.

As we head into Week 7 of the 2025 NFL season, every game feels a little more meaningful. We're continuing to separate the contenders from the pretenders.

The week starts with a divisional Thursday night matchup between two QBs who are sailing into middle age. The main Sunday slate features Mike Vrabel's quest for revenge in Music City, the free-falling Eagles looking to stop the bleeding in Minnesota, and a banged-up Niners squad taking on a red-hot Falcons group.

Through the good, bad, and ugly, we'll dive into all the unique spots on this slate, as we go through every Week 7 game in this article, offering picks, predictions, and analysis for each and every one. Thanks for joining us here at RotoBaller; let's dive in!

Pittsburgh Steelers 27, Cincinnati Bengals 20 (Thursday Night)

We kick off Week 7 of the NFL season with an AFC North clash between divisional rivals who are headed in different directions. The Aaron Rodgers experiment has paid off for the Steelers to this point, as the 41-year-old has helped Pittsburgh get off to a 4-1 start and an early stranglehold on the division.

Battle of the uncs on TNF 😈

PITvsCIN- Thursday 8:15pm ET on Prime Video
Also streaming on @NFLPlus pic.twitter.com/xscdTZy3ti

— NFL (@NFL) October 14, 2025

2025 has been quite the opposite experience for the Bengals, who lost Joe Burrow midway through Week 2 and have promptly gone 0-4 in games without Burrow starting under center. A desperation trade for Joe Flacco might help to an extent, but it's the Cincy defense that's really to blame, as they are one of only three NFL teams allowing over 30 points per game.

Upsets have been the trend on Thursday nights in recent weeks - and I look for the Bengals to be fairly competitive in this one - but expect the Bengals defense to ultimately falter against a Steelers offense that's finding a bit of rhythm with Rodgers at the helm.

Los Angeles Rams 24, Jacksonville Jaguars 20 (London)

Football fans in London will be treated to a good matchup between a pair of 4-2 teams, as the Rams and Jags kick off the Sunday slate from across the pond. Liam Coen's 4-2 start in his first season as the head man in Duval County is impressive, but Jacksonville could run into trouble in this matchup.

There are a couple of "strength vs. weakness" pressure points in this matchup. The Jags are allowing the NFL's third-most passing yards per game (256.3) and veteran quarterback Matthew Stafford is fully capable of taking advantage of this porous Jacksonville secondary. We've also seen the Jaguars' protection of Trevor Lawrence start to lapse - they gave up an eye-popping 7 sacks to Seattle last week. That's not a good sign heading into a matchup against Jared Verse and an aggressive L.A. pass rush.

New England Patriots 28, Tennessee Titans 13

Mike Vrabel returns to Music City with his new-look Patriots sporting a 4-2 record. This Tennessee organization has been a dumpster fire in recent years, which was likely a big part of the reason that Vrabel got out of dodge. The Titans made yet another big change this week by firing second-year head coach Brian Callahan.

Titans part ways with HC Brian Callahan. pic.twitter.com/KTIZacl3Xn

— NFL (@NFL) October 13, 2025

From an on-field perspective, New England is doing lots of things right, while Tennessee is doing nearly everything wrong. Drake Maye looks to be on a franchise-QB trajectory, while No. 1 overall pick Cam Ward has been constantly under siege behind a sieve-like Titans offensive line that's allowed an NFL-high 25 sacks. Vrabel is unlikely to pull any punches in this one with the Pats covering the number.

Chicago Bears 27, New Orleans Saints 20

Many predicted the Saints to be the worst team in the NFL this season, and their 1-5 start has done little to prove those projections wrong. In fairness to New Orleans, Kellen Moore's team has been competitive at home. However, they have struggled mightily outside of the Superdome this year, losing their two road games by a combined 43 points.

Following a two-game homestand, the Saints must travel to the Windy City to face a surging Bears squad that's reeled off three straight wins following an 0-2 start. Chicago hasn't reached world-beater status yet, but they are doing enough right to take care of the Saints at home.

Miami Dolphins 21, Cleveland Browns 20

This is one for the hardcore fans only, as the 1-5 Dolphins travel to Cleveland to face the 1-5 Browns. If you can stand to watch this one, you'll see a pair of teams that have been rudderless in 2025 - Cleveland on the offensive side of the ball and Miami on defense.

For all of their issues, Mike McDaniel's Fins are at least scoring some points. Since their disastrous season opener, Miami has posted 21 or more points in every game. The problem? Their defense is getting cooked on a weekly basis, coughing up an eye-popping average of over 400 total yards and 29 points per game.

Despite those defensive issues, it's fair to wonder if Cleveland can capitalize. They come in averaging a league-worst 13.7 points per game and failed to find the endzone with Dillon Gabriel at the helm last week.

Carolina Panthers 27, New York Jets 23

Are the Panthers actually...good? While the answer is almost certainly "no", Carolina comes into Week 7 having won three of their last four while playing largely quality football. The offense has been sparked by the insertion of running back Rico Dowdle into the starting lineup. Playing in place of the injured Chuba Hubbard, Dowdle has amassed a mind-blowing 473 total yards with two TDs across Carolina's last two games.

Rico Dowdle has more yards from scrimmage in his last 2 games than Saquon Barkley has all season 🤯 pic.twitter.com/SdyOJZb952

— NFL on CBS 🏈 (@NFLonCBS) October 13, 2025

For all Dowdle's recent success, it could be Bryce Young and Tetairoa McMillan who hit paydirt this week against a Jets defense that ranks dead last in the NFL in passing yards allowed per game (144.2). Gang Green's offense has been DOA with Justin Fields in recent weeks and will very likely be without star receiver Garrett Wilson in this one.

Philadelphia Eagles 23, Minnesota Vikings 21

As of this writing we don't know if it will be Carson Wentz or J.J. McCarthy under center for the Vikings in Week 7. What we do know is that the Eagles travel to Minnesota in desperate need of a get-right game following two consecutive losses.

Both of these squads should be well rested - Minnesota coming off a Week 6 bye and Philly with some extra days following a Thursday night game - but it's fair to wonder how much traction either of these offenses will find. The Vikings have well known QB issues, while the Eagles' attack has been predictable and ineffective.

Despite their recent struggles, I expect Philly to right the ship to some extent with their still-talented defense forcing some mistakes out of whoever winds up under center for the Vikes.

Kansas City Chiefs 31, Las Vegas Raiders 17

A 30-17 victory over the Lions on Sunday night indicates the Chiefs might finally be getting their groove back. With the offense trending up, they will also be getting star receiver Rashee Rice back from a six-game suspension in this Week 7 divisional matchup against the Raiders.

Kansas City will look to get their record above .500 for the first time in 2025, and the Raiders' resume this season gives us little reason to think they'll offer much resistance in Arrowhead Stadium. Offseason acquisition Geno Smith has been abysmal to this point, already tossing 10 INTs behind an injury-ravaged Vegas offensive line. Chris Jones and company will continue to make life difficult for Smith this week.

Denver Broncos 23, New York Giants 17

The suddenly-fun Giants shocked the Eagles last Thursday night behind the play of rookies Jaxson Dart and Cam Skattebo, logging a decisive 34-17 win over the defending Super Bowl champs and their long-time divisional rivals. Big Blue has now won two of three since inserting Dart into the starting lineup.

Giants take up 3 spots on ESPN's top 10 rookie rankings ⤵️

📰: https://t.co/iHN7E0JeDs pic.twitter.com/GkWGbEUMpb

— Matt Citak (@MattCitak) October 16, 2025

While optimism is running high in the Big Apple, a trip to Mile High this week might be a reason to pump the brakes. Denver is still struggling to find consistency on offense, but their defense has performed at an elite level during their current three-game win streak.

The Broncos are shutting opponents down both through the air (165.2 yards per game) and on the ground (89.0 yards per game). So, while Giants fans should be excited about their emerging young core, Dart and company are likely to be held in check in this tough spot.

Indianapolis Colts 24, Los Angeles Chargers 23

The NFL's biggest shocker through the first six weeks, the Colts are a bone-headed AD Mitchell fumble away from being 6-0. A preseason QB controversy has turned into a windfall for Indy, as the decision to make Daniel Jones their starter has resulted in star-caliber play from Jones and an NFL-best 32.3 points per game.

While Danny Dimes has been the story, the unbelievable play of Jonathan Taylor shouldn't go overlooked, as he leads the league in rushing yards (603) and TDs (7). He'll square off against a Chargers that's allowing a shade over 124 rushing yards per game.

Jim Harbaugh's crew has lost two of three after a fast 3-0 start. The recent dip can be largely attributed to multiple injuries to key players, most notably franchise left tackle Joe Alt. I expect those issues along the line of scrimmage to hamper the Bolts in this matchup against a trending Colts squad.

Washington Commanders 31, Dallas Cowboys 27

Both of these NFC East divisional rivals come into this one on the heels of brutal Week 6 losses. The Commanders were a 3rd-and-1 away from icing the Bears on Monday Night Football, but a botched handoff led to a fumble and defeat. Meanwhile, the Cowboys coughed up 410 total yards in a road loss to Carolina.

We'll need more info as the week progresses, as both squads have some key players in different stages of questionable for this matchup. There are rumblings that star Cowboys receiver CeeDee Lamb could return, while the status of Washington wideouts Terry McLaurin and Deebo Samuel is also up in the air as of this writing.

Taking those moving parts into consideration, it's nearly impossible to put any trust in a putrid Dallas defense that's dead last in the NFL in total yards allowed per game. Look for Jayden Daniels and the Commanders to get back on track here.

Green Bay Packers 23, Arizona Cardinals 14

Jacoby Brissett got the start at QB for the Cardinals last week in place of the injured Kyler Murray. He didn't look like that much of a downgrade, nearly leading Arizona to an upset of the Colts in Week 6.

With Murray questionable for this Week 7 tilt against the Packers, we'll assume that Brissett will again be in the lineup, and while he might be better for the Cardinals passing attack than Murray, he definitely can't evade pressure at the same level. Micah Parsons and company could feast on the statuesque Brissett, who might not have Marvin Harrison Jr. (concussion) to throw to in this one.

Atlanta Falcons 21, San Francisco 49ers 20 (Sunday Night)

The Niners have been so ravaged by injuries to key personnel that it's become almost impossible to project what team Kyle Shanahan will be able to put on the field. As of this writing, both Brock Purdy and Mac Jones are banged up, George Kittle has returned to practice, while Ricky Pearsall and Jauan Jennings sport questionable tags.

Quick news dispatch from today: #49ers QB Brock Purdy (toe) back at practice on limited basis, as is TE George Kittle. No WR Ricky Pearsall. LB Fred Warner had his surgery...https://t.co/JpLxcFuS4j

— Nick Wagoner (@nwagoner) October 15, 2025

Yeah... it's a lot, and to top it off, San Fran linebacker Fred Warner will join Nick Bosa on the sidelines for the rest of the season following an ankle injury suffered last week.

Aside from wide receiver Darnell Mooney, the Falcons are relatively healthy. However, they remain frustratingly unpredictable. Will we get the team that handled Buffalo on Monday night or the squad that was destroyed 30-0 by Carolina in Week 3? While it's admittedly uncomfortable taking Atlanta outside of Mercedes-Benz Stadium, I'll ride their elite rushing attack and trending defense in a small upset over the banged-up Niners.

Tampa Bay Bucs 35, Detroit Lions 31 (Monday Night)

Will the real NFC frontrunner please stand up? If the NFL Playoffs started today, Baker Mayfield and the Bucs would hold the No. 1 seed. Dan Campbell and the Lions have sandwiched dominant performances over lesser teams between a Week 1 blowout loss to the Packers and last week's 30-17 loss to the Chiefs.

The smart money points towards Detroit in this one, as they've been largely dominant at home in the Dan Campbell era. Not to mention that the Bucs are dealing with a multitude of injuries. However, sometimes the madder guy wins the fight, and no one is playing with more fire than Baker Mayfield at this moment.

Seattle Seahawks 20, Houston Texans 17 (Monday Night)

We close out the Week 7 slate with an intriguing matchup between the Seahawks and Texans. Prior to their Week 6 bye, Houston had battled back from an 0-3 start to win their last two. They'll look to take the momentum to the raucous environment of Lumen Field against a Seattle group that's won four of their last five.

While Houston's defense is rock solid, and could force Sam Darnold into some mistakes, it's impossible to ignore the gaping hole that is the Texans offensive line. Seattle logged a league-high seven sacks against Jacksonville last week, and head coach Mike Macdonald will exploit and expose Houston's Achilles' heel in this matchup.

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