TAP FOR 6 MONTHS OF PREMIUM FREE 💰
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

Free MLB Betting Picks - Today's Best Bets, Expert Predictions, Odds (4/21/22)

juan soto fantasy baseball rankings outfield MLB injury news

John Brubaker's top MLB betting picks and best bets for today's MLB games on 4/21/22. His free picks against the spread, teasers, parlays, and MLB player props.

Happy Thursday, RotoBallers! We had ourselves a decent day Sunday, again finishing 1-1. A bit frustrating to finish with these 1-1 days with plays in the article, but we just have to take it to the chin. The entire RotoBaller team has been working around the clock to make sure we can get you guys the best betting picks, props, and lineups for the opening throughout the season. We're happy you're here with us and are looking forward to an extremely profitable 2022 season!

Attention fellow sports bettors! We have some exciting news to share as we are now officially partnered with various sportsbooks and have some sweet sports betting promo offers! Get your deposit bonus, as well as a year of free RotoBaller Premium access, when you sign up with a new account today! After you're signed up, use our picks in this article for spreads, totals, and props to win big.

If you're new, or just a refresher to those who read my articles last season, I'm John Brubaker. I've been betting MLB baseball games for four years now, and this is my second MLB season working with the great folks at RotoBaller. I've created my own betting model to help me create and identify value on run lines, totals, and money lines. In this article, I'll be providing my favorite betting picks MLB games on Thursday, April 21, 2022. I'm continuously working to improve my models to make them more accurate, and as the season progresses, I'll share the data I have on my personal Twitter @LucidMediaDFS. Feel free to give me a follow if you haven't already, and do not hesitate to ask any questions! My DMs are always open. With all of that said, let's break down some baseball games.

Featured Promo: New Novig users get a $25 purchase match (50% discount up to $25) on your first Novig deposit, and 6 free months of RotoBaller's "Big-4" Premium Pass (NFL, NBA, MLB, NHL) which includes exclusive tools for Betting, Props, DFS and more! CLAIM IT NOW

 

LucidMedia's 2022 MLB Betting Picks

  • Season to Date: 8-7-1, -1.4 units
  • Sides: 6-4, +0.38 units
  • Totals: 2-3-1, -1.78 units
  • Notes:

 

Baltimore Orioles @ Oakland Athletics

O/U: 7.5 | Moneyline: OAK -134

BAL: Tyler Wells | OAK: Paul Blackburn

I'll start today's slate off out in Oakland, where it's super unfortunate to see what's going on with attendance numbers out there. Nevertheless, I'm on the future "Las Vegas Athletics" today. They'll send Paul Blackburn to the mound, who has seemingly greatly improved his stuff prior to this season. Blackburn is 1-0 with a 1.80 ERA and a 1.89 xFIP in two starts on the year, with the A's picking up the win in both.

On the other side of the matchup, we have Tyler Wells. Wells comes into this one with an 0-1 record, 6.35 ERA, and 4.89 xFIP. The xFIP to ERA regression shows that Wells has been a bit unlucky when allowing runs, but I still think he's a mediocre starter. My model's data agrees, with Tyler Wells coming into this one with a 54.51 rating while Blackburn brings in a 63.83 rating.

FanDuel Sportsbook has the A's at -134 right now, giving us implied odds of 59.68%. My model gives the A's a 65.83% chance to win the game, giving us some solid value here (+6.15%), winning by a final score of 4.78-3.74. Wells has lost his only two outings as a starter, while the Athletics are 3-1 in Blackburn's last four starts. Although the Orioles stole one last night, Oakland was 4-0 in their last four home games against a right-handed starter, and I like them to get this one.

Pick: Oakland Athletics Money Line (-134) FanDuel Sportsbook, 1 unit

 

Arizona Diamondbacks @ Washington Nationals

O/U: 8.5 | Moneyline: WSH -136

ARI: Zach Davies | WSH: Josh Rogers

I'll be looking at an over in this one, as the Arizona Diamondbacks and Washington Nationals wrap up their series. The Diamondbacks will send Zach Davies to the mound, who comes into this one 0-1 with a 5.79 ERA and a 5.07 xFIP. While the Nationals aren't an offensive powerhouse, they do grade well against Davies, particularly at the top of their lineup.

Josh Rogers takes the ball for Washington, coming into this one 1-1 with a 3.72 ERA. However, we can conclude Rogers has been a bit lucky while on the mound, considering his 5.08 xFIP actually comes in worse than Zach Davies. Arizona isn't quite the offensive powerhouse either, ranking near the bottom of the league in runs per game, but I can't see Rogers continuing to pitch at a high rate. None of the Diamondbacks have faced Rogers yet, but a solid amount of hitters (Hummel, Marte, Kelly, and Walker) grade out well against the southpaw.

FanDuel Sportsbook has the over at 8.5 here, at -132. It's a bit juiced for my liking, with implied odds of 56.9%, but my model still has it blowing past this number. With a 62.63% chance of going over and a total finishing at 10.07, I believe there's solid value here. Over 8.5 has hit in five of Davies's last six starts, as well as his last start against the Nationals (5/18/2021, while he was pitching for the Cubs). It's hit in four of Rogers's past six starts as well. While the under has been the play in this series outside of last night's game, the over is 4-0 in the Diamondbacks' last "game-fours" of a series, as well as going 5-0-1 in Washington's last six against a right-handed starter. I hope this one isn't an offensive struggle, because there's some solid value here.

Pick: Diamondbacks @ Nationals, over 8.5 (-132) FanDuel Sportsbook, 1 unit

 

Good to be back Rotoballers! Stay tuned for my plays through the rest of the week and weekend. Good luck!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!



More Fantasy Baseball Analysis

POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Max Scherzer

Could Make Grapefruit League Debut This Weekend
Alex DeBrincat

Collects Two More Points
Andrew Benintendi

Should be Back on Thursday
Kirill Marchenko

Earns Three Points on Monday
Nicolai Hojgaard

Continues to Search for First PGA Tour Victory at API
Xander Bogaerts

the Leading Candidate to Hit Leadoff for Padres
Shane Lowry

Trying to Shake Off Last Week's Heartbreak at the API
Fernando Tatis Jr.

Moving to Middle of the Batting Order?
Kyle Stowers

Doing Baseball Activities, to Start Running Progression Soon
Matt Fitzpatrick

Continues Scorching Start to 2026 Season
Keegan Bradley

Searching for Better Results Heading to Bay Hill
Cedric Mullins

Goes Deep for First Time in Rays Uniform
Jac Caglianone

Looking Good at the Plate So Far This Spring
Isaac Paredes

Homers in Spring Debut
Logan Webb

to Start WBC Opener for Team USA on Friday
Tarik Skubal

Scheduled to Throw Around 55 Pitches Against Great Britain
Kyle Freeland

to Make Spring Debut on Wednesday
P.J. Washington

Questionable vs. Hornets
Dairon Blanco

Designated for Assignment by Royals
Egor Demin

to Miss Second Straight Game
Nicolas Claxton

Expected to Play on Tuesday
Coby White

Ruled Out vs. Dallas
Jacob deGrom

to Make Spring Debut on Wednesday
Kyle Hurt

Being Viewed as Reliever
Collin Murray-Boyles

to Miss Second Straight Game
Naji Marshall

Unavailable Versus Charlotte
Donovan Mitchell

Out Tuesday vs. Detroit
Cooper Flagg

Listed as Doubtful for Tuesday Night
Beau Brieske

Exits With Rib-Cage Injury
Shai Gilgeous-Alexander

Ruled Out for Tuesday's Matchup With Bulls
Isaiah Hartenstein

to Miss Game Against Bulls
Anthony Gill

Out, Julian Reese Set to Start Monday
Kris Dunn

Available On Monday Against Warriors
John Collins

Sidelined vs. Warriors
Giannis Antetokounmpo

Set to Suit Up Monday
Neemias Queta

Gets Rest Day vs. Milwaukee
Jayson Tatum

Reportedly Set for Friday Comeback
Tristan Vukcevic

Ruled Out Versus Houston
Denver Nuggets

Tyus Jones Inks Deal with Nuggets
Trevor Moore

Unavailable Monday
Kyshawn George

Will Face the Rockets
Drew Doughty

Could Return Thursday
Cameron Johnson

Out Monday Against Jazz
Roope Hintz

Misses Third Consecutive Game
Zach Werenski

Iffy for Monday's Action
Trae Young

Ready to Make Wizards Debut on Thursday
Travis Konecny

a Game-Time Decision Monday
John Gibson

Exits Win Early
Connor Murphy

Moving to Edmonton
Zach Neto

Scorching-Hot Early in Spring Training
Grayson Rodriguez

Happy With his Secondary Pitches
Gavin Stone

has "Setback" With his Shoulder, "Paused" From Throwing
Khalil Mack

Will Play in 2026
MMA

Lone'er Kavanagh Gets Back In The Win Column
Alex Verdugo

Padres Add Alex Verdugo on Minor-League Deal
Joe Musgrove

to Start Exhibition Game on Wednesday
Brandon Moreno

Gets Outclassed
Masyn Winn

Sits Out on Monday Due to Arm Soreness
Marlon Vera

Loses Fourth Fight In A Row
Daniel Jones

Colts Have "50/50" Chance to Get a Deal Done With Daniel Jones
David Martinez

Remains Undefeated In The UFC
Daniel Zellhuber

Loses Third Consecutive Fight
King Green

Gets Second-Round TKO Win
Felipe Bunes

Drops Decision At UFC Mexico City
Édgar Cháirez

Edgar Chairez Wins Back-To-Back Fights
Ryan Blaney

Falls to Eighth Despite Running Most of the Race in the Top Five At COTA
Ty Gibbs

Wins A Stage and Finishes Fourth At COTA
Christopher Bell

Earns First Top-Five Finish of the 2026 Season at COTA
Kyler Murray

"Repeatedly" Linked to Jets
Shane Van Gisbergen

Falls Short of Victory At COTA
Tyler Reddick

Wins At COTA and Makes NASCAR History
David Montgomery

Texans Acquire David Montgomery From Lions
Lukas Dostal

Sets New Career High With 24th Win
Cutter Gauthier

Hits Two Goals in Shootout Win
Robert Thomas

Returns to Action With Multi-Point Effort
Matthew Tkachuk

Dishes Out Three Assists Sunday
Matthew Schaefer

Has First Three-Point Outing
Teuvo Teravainen

Pots Two Goals In Sunday's Win
Arvid Soderblom

Keeps Mammoth Quiet
Bryan Rust

With a Strong Two-Point Game
Arturs Silovs

Earns a Shutout on Sunday Afternoon
Jonathan Drouin

Unavailable Sunday
Darcy Kuemper

Won't Play Monday Due to Illness
EDM

Oilers Place Andrew Mangiapane on Waivers
Kyler Murray

Likely to be Released
Travis Etienne Jr.

Not Expected to be Franchise-Tagged
Aaron Jones Sr.

Vikings Planning to Release Aaron Jones Sr.?
Tyler Reddick

Could Make History at COTA
Shane Van Gisbergen

Shane van Gisbergen Still the Favorite at COTA
Christopher Bell

Will Be Tough to Beat at COTA
AJ Allmendinger

Could Contend at COTA
Connor Zilisch

Carries Plenty of Upside for DFS at COTA
Chase Elliott

May be A Strong Contender Again at COTA
Chris Buescher

Is Nothing But Consistent at Road Courses
Ross Chastain

May Be An Underrated Competitor for the Win at COTA
William Byron

Is William Byron a Viable DFS Option for COTA?
Carson Hocevar

Needs Clean Race at COTA
Kyle Larson

Could be A Decent DFS Option for COTA Lineups
Ryan Blaney

Could Ryan Blaney be A Sleeper DFS Option for All Formats for COTA?
Chase Briscoe

Should DFS Players Roster Chase Briscoe at COTA?
NASCAR

Bubba Wallace Is A Favorable Value Option for COTA DFS Lineups
Ty Gibbs

Could Ty Gibbs Be A Rosterable DFS Play for COTA?
Michael McDowell

Is Michael McDowell A Favorable DFS Option for COTA?
A.J. Brown

Patriots "Have Explored Trade Talks" Involving A.J. Brown
Lone'er Kavanagh

Set For UFC Mexico City Main Event
Brandon Moreno

Looks To Bounce Back
David Martinez

Set For UFC Mexico City Co-Main Event
Marlon Vera

In Dire Need Of Victory
King Green

Looks To Win Back-To-Back Fights
Daniel Zellhuber

Aims To Snap Two-Fight Skid
Felipe Bunes

Looks To Get Back In The Win Column
Édgar Cháirez

Edgar Chairez A Favorite At UFC Mexico City
George Pickens

Cowboys Not Interested in Trading George Pickens
Ashton Jeanty

Not in Line for Workhorse Role in 2026?
Anthony Richardson Sr.

Colts Give Anthony Richardson Sr. Permission to Seek a Trade
Kyler Murray

Prefers to be Released
Derek Carr

"Strong Belief" That Derek Carr is "Very Serious" About Unretiring
Andy Dalton

Is Andy Dalton Available for a Trade?
Keith Mitchell

Making The Comfortable Return to PGA National
CFB

Chandler Morris Suing NCAA for Seventh Year of Eligibility
Chris Kirk

Searching for a Spark at Cognizant Classic
Brooks Koepka

Making Third PGA Tour Start at Cognizant Classic
Mackenzie Hughes

a Steady Option at Cognizant Classic
Seamus Power

Seeking More Green in Florida
PGA

Haotong Li Back From a Break as Florida Stretch Starts
Stephan Jaeger

Trying to Put Four Rounds Together in Florida
PGA

Nico Echavarria Again Attempting to Make the Weekend
Patrick Fishburn

Looking for a Spark at Cognizant Classic
Blades Brown

Set for Cognizant Classic Debut
Michael Thorbjornsen

Looking to Bounce Back at Cognizant Classic
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF