👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


Free MLB Betting Picks - Today's Best Bets, Expert Predictions, Odds (4/21/22)

juan soto fantasy baseball rankings outfield MLB injury news

John Brubaker's top MLB betting picks and best bets for today's MLB games on 4/21/22. His free picks against the spread, teasers, parlays, and MLB player props.

Happy Thursday, RotoBallers! We had ourselves a decent day Sunday, again finishing 1-1. A bit frustrating to finish with these 1-1 days with plays in the article, but we just have to take it to the chin. The entire RotoBaller team has been working around the clock to make sure we can get you guys the best betting picks, props, and lineups for the opening throughout the season. We're happy you're here with us and are looking forward to an extremely profitable 2022 season!

Attention fellow sports bettors! We have some exciting news to share as we are now officially partnered with various sportsbooks and have some sweet sports betting promo offers! Get your deposit bonus, as well as a year of free RotoBaller Premium access, when you sign up with a new account today! After you're signed up, use our picks in this article for spreads, totals, and props to win big.

If you're new, or just a refresher to those who read my articles last season, I'm John Brubaker. I've been betting MLB baseball games for four years now, and this is my second MLB season working with the great folks at RotoBaller. I've created my own betting model to help me create and identify value on run lines, totals, and money lines. In this article, I'll be providing my favorite betting picks MLB games on Thursday, April 21, 2022. I'm continuously working to improve my models to make them more accurate, and as the season progresses, I'll share the data I have on my personal Twitter @LucidMediaDFS. Feel free to give me a follow if you haven't already, and do not hesitate to ask any questions! My DMs are always open. With all of that said, let's break down some baseball games.

Featured Promo: New Novig users get a $25 purchase match (50% discount up to $25) on your first Novig deposit, and 6 free months of RotoBaller's "Big-4" Premium Pass (NFL, NBA, MLB, NHL) which includes exclusive tools for Betting, Props, DFS and more! CLAIM IT NOW

 

LucidMedia's 2022 MLB Betting Picks

  • Season to Date: 8-7-1, -1.4 units
  • Sides: 6-4, +0.38 units
  • Totals: 2-3-1, -1.78 units
  • Notes:

 

Baltimore Orioles @ Oakland Athletics

O/U: 7.5 | Moneyline: OAK -134

BAL: Tyler Wells | OAK: Paul Blackburn

I'll start today's slate off out in Oakland, where it's super unfortunate to see what's going on with attendance numbers out there. Nevertheless, I'm on the future "Las Vegas Athletics" today. They'll send Paul Blackburn to the mound, who has seemingly greatly improved his stuff prior to this season. Blackburn is 1-0 with a 1.80 ERA and a 1.89 xFIP in two starts on the year, with the A's picking up the win in both.

On the other side of the matchup, we have Tyler Wells. Wells comes into this one with an 0-1 record, 6.35 ERA, and 4.89 xFIP. The xFIP to ERA regression shows that Wells has been a bit unlucky when allowing runs, but I still think he's a mediocre starter. My model's data agrees, with Tyler Wells coming into this one with a 54.51 rating while Blackburn brings in a 63.83 rating.

FanDuel Sportsbook has the A's at -134 right now, giving us implied odds of 59.68%. My model gives the A's a 65.83% chance to win the game, giving us some solid value here (+6.15%), winning by a final score of 4.78-3.74. Wells has lost his only two outings as a starter, while the Athletics are 3-1 in Blackburn's last four starts. Although the Orioles stole one last night, Oakland was 4-0 in their last four home games against a right-handed starter, and I like them to get this one.

Pick: Oakland Athletics Money Line (-134) FanDuel Sportsbook, 1 unit

 

Arizona Diamondbacks @ Washington Nationals

O/U: 8.5 | Moneyline: WSH -136

ARI: Zach Davies | WSH: Josh Rogers

I'll be looking at an over in this one, as the Arizona Diamondbacks and Washington Nationals wrap up their series. The Diamondbacks will send Zach Davies to the mound, who comes into this one 0-1 with a 5.79 ERA and a 5.07 xFIP. While the Nationals aren't an offensive powerhouse, they do grade well against Davies, particularly at the top of their lineup.

Josh Rogers takes the ball for Washington, coming into this one 1-1 with a 3.72 ERA. However, we can conclude Rogers has been a bit lucky while on the mound, considering his 5.08 xFIP actually comes in worse than Zach Davies. Arizona isn't quite the offensive powerhouse either, ranking near the bottom of the league in runs per game, but I can't see Rogers continuing to pitch at a high rate. None of the Diamondbacks have faced Rogers yet, but a solid amount of hitters (Hummel, Marte, Kelly, and Walker) grade out well against the southpaw.

FanDuel Sportsbook has the over at 8.5 here, at -132. It's a bit juiced for my liking, with implied odds of 56.9%, but my model still has it blowing past this number. With a 62.63% chance of going over and a total finishing at 10.07, I believe there's solid value here. Over 8.5 has hit in five of Davies's last six starts, as well as his last start against the Nationals (5/18/2021, while he was pitching for the Cubs). It's hit in four of Rogers's past six starts as well. While the under has been the play in this series outside of last night's game, the over is 4-0 in the Diamondbacks' last "game-fours" of a series, as well as going 5-0-1 in Washington's last six against a right-handed starter. I hope this one isn't an offensive struggle, because there's some solid value here.

Pick: Diamondbacks @ Nationals, over 8.5 (-132) FanDuel Sportsbook, 1 unit

 

Good to be back Rotoballers! Stay tuned for my plays through the rest of the week and weekend. Good luck!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!



More Fantasy Baseball Analysis

REAL-TIME FANTASY NEWS

J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Germie Bernard

Already in a Tough Spot to Hold Dynasty Value
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Denzel Boston

a Smart Bet to Meet or Exceed Value in Dynasty Rookie Drafts
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Matthew Stafford

a Sell Candidate with Touchdown Regression Likely on its Way
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

Comes Alive in Game 5 Against Timberwolves
Jayden Reed

Dynasty Value Tethered to His Underwhelming Usage
Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Kenyon Sadiq

Is Kenyon Sadiq the Next Great Rookie Tight End?
Victor Wembanyama

Leads Spurs to Big Win in Game 5
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Mason McTavish

Delivers Two Assists Tuesday Night
Pavel Dorofeyev

Pots Two Goals in Vital Game 5 Win
Josh Doan

Records Two Assists in Game 4 Victory
Evgeni Malkin

Penguins Want Evgeni Malkin Back
Sidney Crosby

Joins Team Canada for World Championship
Ryan Poehling

Suffers Upper-Body Injury in Game 5 Loss
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Jon Rahm

Having Excellent Season On LIV Tour
Cade Klubnik

Becoming Fan Favorite, in Play to Win Backup QB Job?
Michael Penix Jr.

Throwing During Offseason Program
Bryce Young

Panthers Will Continue to Discuss Extension With Bryce Young
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Michael Mayer

More Opportunities Coming for Michael Mayer?
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Dylan Harper

Cleared for Action Tuesday
De'Aaron Fox

Available for Game 5 Against Timberwolves
Caris LeVert

Remains on Injury Report With Heel Issue
Duncan Robinson

Listed as Questionable for Game 5
Brandon Clarke

Dies at Age 29
Charlie McAvoy

Slapped With Six-Game Suspension
Jonas Brodin

Unavailable for Game 5 Against Avalanche
Joel Eriksson Ek

to Remain Out Wednesday
Sam Malinski

Day-to-Day With Upper-Body Injury
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Artturi Lehkonen

Considered Day-to-Day
Charlie Coyle

Lands Six-Year Extension
Ukko-Pekka Luukkonen

to Start Game 4 Against Canadiens
Drew Helleson

Unavailable for Game 5
Radko Gudas

Still Out Tuesday
Mark Stone

Won't Play Tuesday
Carnell Tate

Is Carnell Tate Poised for Immediate Stardom in Tennessee?
Jeremiyah Love

Will Jeremiyah Love See a Limited Role in Arizona as a Rookie?
Wan'Dale Robinson

Dynasty Stock Fading Following NFL Draft
Bucky Irving

Not Yet Cleared to Participate in OTAs
Tyler Shough

Dynasty Stock Rising with Improved Supporting Cast in New Orleans
Garrett Wilson

Dynasty Upside Limited by Quarterback Questions
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
Ted Hurst

Viewed as "True X" Receiver Going into Rookie Campaign
Kenneth Gainwell

Zac Robinson Thinks Bucky Irving, Kenneth Gainwell Have Similar Skill Sets
Emeka Egbuka

to Settle into "Z" Role in Year 2
Trey Benson

Droppable in Some Dynasty Leagues?
Cameron Ward

Looking to Make a Year 2 Leap
Omar Cooper Jr.

to Require Some Patience in Dynasty Leagues?
Luka Dončić

Luka Doncic Admits He Wasn't Close to Returning Before Season Ended
CFB

Isaac Brown Has All-American Upside in 2026
LeBron James

Uncertain About Future After Season-Ending Loss
Ajay Mitchell

Continues to Excel for Thunder
CFB

Nyck Harbor Heading into Breakout Year?
Shai Gilgeous-Alexander

Posts 35 Points in Series Clincher
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
Cade Cunningham

Struggles in Game 4 Loss
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
James Harden

Records 40th Postseason Double-Double
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
Donovan Mitchell

Ties NBA Playoff Record With 39 Second-Half Points
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Mark Jankowski

Signs Two-Year Extension With Hurricanes
Joel Kiviranta

Cleared to Play Monday
Josh Manson

Available for Game 4 Monday
Mackenzie Blackwood

Expected to Start Monday
Jonas Brodin

Won't Play Monday
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
Luis Castillo

Mariners Intend to Piggyback Luis Castillo, Bryce Miller
Logan Webb

Placed on 15-Day Injured List With Knee Bursitis
Bryce Miller

is Set to Return on Wednesday
Jeff Hoffman

Could Return to Closer Role
Taj Bradley

Hits the Injured List With Pectoral Inflammation
Kyle Bradish

has Nice Bounce-Back Performance With 10 K's
Casey Mize

Throws Bullpen on Friday, Return Not Imminent
Ronald Acuña Jr.

Ronald Acuna Jr. Optimistic About Returning Next Wednesday
Tyler Glasnow

Dodgers Put Tyler Glasnow on Injured List With Back Spasms
Blake Snell

to Make Season Debut for Dodgers on Saturday
Cole Ragans

Royals Place Cole Ragans on Injured List With Elbow Impingement
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
Nick Lodolo

Officially Activated, Making Season Debut on Friday
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
CFB

Rasheem Biles an Instant Impact Player for Texas
CFB

Sam Leavitt Expected to Be Full-Go for Fall Camp
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF