👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

#1 Expert Projections
Save 50% Now
Import Your Leagues
Props Tool
Compare Any Players
Compare Any Players
24x7 News and Alerts

Free MLB Betting Picks - Today's Best Bets, Expert Predictions, Odds (4/21/22)

juan soto fantasy baseball rankings outfield MLB injury news

John Brubaker's top MLB betting picks and best bets for today's MLB games on 4/21/22. His free picks against the spread, teasers, parlays, and MLB player props.

Happy Thursday, RotoBallers! We had ourselves a decent day Sunday, again finishing 1-1. A bit frustrating to finish with these 1-1 days with plays in the article, but we just have to take it to the chin. The entire RotoBaller team has been working around the clock to make sure we can get you guys the best betting picks, props, and lineups for the opening throughout the season. We're happy you're here with us and are looking forward to an extremely profitable 2022 season!

Attention fellow sports bettors! We have some exciting news to share as we are now officially partnered with various sportsbooks and have some sweet sports betting promo offers! Get your deposit bonus, as well as a year of free RotoBaller Premium access, when you sign up with a new account today! After you're signed up, use our picks in this article for spreads, totals, and props to win big.

If you're new, or just a refresher to those who read my articles last season, I'm John Brubaker. I've been betting MLB baseball games for four years now, and this is my second MLB season working with the great folks at RotoBaller. I've created my own betting model to help me create and identify value on run lines, totals, and money lines. In this article, I'll be providing my favorite betting picks MLB games on Thursday, April 21, 2022. I'm continuously working to improve my models to make them more accurate, and as the season progresses, I'll share the data I have on my personal Twitter @LucidMediaDFS. Feel free to give me a follow if you haven't already, and do not hesitate to ask any questions! My DMs are always open. With all of that said, let's break down some baseball games.

Featured Promo: New Novig users get a $25 purchase match (50% discount up to $25) on your first Novig deposit, and 6 free months of RotoBaller's "Big-4" Premium Pass (NFL, NBA, MLB, NHL) which includes exclusive tools for Betting, Props, DFS and more! CLAIM IT NOW

 

LucidMedia's 2022 MLB Betting Picks

  • Season to Date: 8-7-1, -1.4 units
  • Sides: 6-4, +0.38 units
  • Totals: 2-3-1, -1.78 units
  • Notes:

 

Baltimore Orioles @ Oakland Athletics

O/U: 7.5 | Moneyline: OAK -134

BAL: Tyler Wells | OAK: Paul Blackburn

I'll start today's slate off out in Oakland, where it's super unfortunate to see what's going on with attendance numbers out there. Nevertheless, I'm on the future "Las Vegas Athletics" today. They'll send Paul Blackburn to the mound, who has seemingly greatly improved his stuff prior to this season. Blackburn is 1-0 with a 1.80 ERA and a 1.89 xFIP in two starts on the year, with the A's picking up the win in both.

On the other side of the matchup, we have Tyler Wells. Wells comes into this one with an 0-1 record, 6.35 ERA, and 4.89 xFIP. The xFIP to ERA regression shows that Wells has been a bit unlucky when allowing runs, but I still think he's a mediocre starter. My model's data agrees, with Tyler Wells coming into this one with a 54.51 rating while Blackburn brings in a 63.83 rating.

FanDuel Sportsbook has the A's at -134 right now, giving us implied odds of 59.68%. My model gives the A's a 65.83% chance to win the game, giving us some solid value here (+6.15%), winning by a final score of 4.78-3.74. Wells has lost his only two outings as a starter, while the Athletics are 3-1 in Blackburn's last four starts. Although the Orioles stole one last night, Oakland was 4-0 in their last four home games against a right-handed starter, and I like them to get this one.

Pick: Oakland Athletics Money Line (-134) FanDuel Sportsbook, 1 unit

 

Arizona Diamondbacks @ Washington Nationals

O/U: 8.5 | Moneyline: WSH -136

ARI: Zach Davies | WSH: Josh Rogers

I'll be looking at an over in this one, as the Arizona Diamondbacks and Washington Nationals wrap up their series. The Diamondbacks will send Zach Davies to the mound, who comes into this one 0-1 with a 5.79 ERA and a 5.07 xFIP. While the Nationals aren't an offensive powerhouse, they do grade well against Davies, particularly at the top of their lineup.

Josh Rogers takes the ball for Washington, coming into this one 1-1 with a 3.72 ERA. However, we can conclude Rogers has been a bit lucky while on the mound, considering his 5.08 xFIP actually comes in worse than Zach Davies. Arizona isn't quite the offensive powerhouse either, ranking near the bottom of the league in runs per game, but I can't see Rogers continuing to pitch at a high rate. None of the Diamondbacks have faced Rogers yet, but a solid amount of hitters (Hummel, Marte, Kelly, and Walker) grade out well against the southpaw.

FanDuel Sportsbook has the over at 8.5 here, at -132. It's a bit juiced for my liking, with implied odds of 56.9%, but my model still has it blowing past this number. With a 62.63% chance of going over and a total finishing at 10.07, I believe there's solid value here. Over 8.5 has hit in five of Davies's last six starts, as well as his last start against the Nationals (5/18/2021, while he was pitching for the Cubs). It's hit in four of Rogers's past six starts as well. While the under has been the play in this series outside of last night's game, the over is 4-0 in the Diamondbacks' last "game-fours" of a series, as well as going 5-0-1 in Washington's last six against a right-handed starter. I hope this one isn't an offensive struggle, because there's some solid value here.

Pick: Diamondbacks @ Nationals, over 8.5 (-132) FanDuel Sportsbook, 1 unit

 

Good to be back Rotoballers! Stay tuned for my plays through the rest of the week and weekend. Good luck!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!



More Fantasy Baseball Analysis

POPULAR FANTASY TOOLS

#1 Expert Projections
Save 50% Now
Import Your Leagues
Props Tool
Compare Any Players
Compare Any Players
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Carson Hocevar

Scores his First Career NASCAR Cup Series Victory at Talladega
Chris Buescher

Misses out on Winning at Talladega by Finishing Second
Alex Bowman

Earns First Top-5 Finish at Talladega Since Returning From Injury
Chase Elliott

Scores A Fourth-Place Finish at Talladega
Zane Smith

Nabs his First Top-5 of the 2026 Season at Talladega
Marvin Harrison Jr.

Does Marvin Harrison Jr. Still Carry High-End Dynasty Upside?
Marquise Brown

Sliding Down Eagles' Depth Chart Following 2026 Draft
Darnell Mooney

Carries Deep-League Buy-Low Upside into 2026
Christian Kirk

Role in San Francisco in Question Following NFL Draft?
CFB

Texas Tech Quarterback Brendan Sorsby Enters Rehab
Youssef Zalal

Suffers Unanimous-Decision Loss
Brashard Smith

Facing an Uphill Battle for Playing Time in Kansas City
Aljamain Sterling

Wins Back-To-Back Fights
Rashee Rice

Can Rashee Rice Put Together a Full Season of Production in 2026?
Norma Dumont

Drops Decision At UFC Vegas 116
Joselyne Edwards

Scores Upset Win
Alexander Hernandez

Gets Dominated
Alexander Hernandez

Rafa Garcia Dominates Alexander Hernandez
Adrian Luna Martinetti

Unsuccessful In His UFC Debut
Davey Grant

Gets Back In The Win Column
Manny Machado

Clubs Two Homers, Starting to Turn Things Around?
Kyren Williams

Becoming a Better Dynasty Value by the Day
Ben Sinnott

Is it Time to Move on From Ben Sinnott?
Sam Darnold

Still a Reliable Dynasty Hold
Brandon Hagel

Pops Up With Two Goals in Sunday's Win
Justin Fields

Could Dynasty Managers See One More Sell Window for Justin Fields?
Nathan MacKinnon

Records Three Points in Series-Clincher
Dallas Goedert

a Dynasty Bargain After Flurry of Eagles' Moves
Bowen Byram

Extends Goal Streak to Three Games
John Carlson

Delivers Two Assists in Game 4 Victory
Connor McDavid

Bags Pair of Power-Play Assists in 100th Playoff Game
Jason Zucker

Makes Early Exit in Blowout Win
De'Aaron Fox

Notches Game-High 28 Points Sunday
Joel Embiid

Returns With Double-Double
Jayson Tatum

Logs 30-Point Double-Double in Sunday's Win
LeBron James

Quiet in Game 4 Loss to Rockets
Julius Randle

Handed $35K Fine for His Part in Game 4 Altercation
Nikola Jokić

Nikola Jokic Fined $50K for Game 4 Incident
Collin Murray-Boyles

Continues to Shine for Raptors
Deni Avdija

Returns to Form Sunday
Victor Wembanyama

Stuffs Stat Sheet in His Return
Austin Reaves

Won't Suit Up Sunday
Jonathan Isaac

Likely to Remain Out Monday
Isaiah Joe

Available for Game 4 Monday
Aaron Gordon

Uncertain for Monday
Jordan Goodwin

Considered Questionable for Monday's Elimination Game
Joel Embiid

Ready to Return Sunday
Mark Williams

to Remain Out Monday
Kevin Huerter

Listed as Questionable for Monday
Kelly Oubre Jr.

Cleared to Play Sunday
Anthony Edwards

Faces Multi-Week Absence
Kevin Durant

Remains Out Sunday
Emil Andrae

Expected to Rejoin Flyers Lineup Monday
Matvei Michkov

Set to Be Scratched for Game 5
Radko Gudas

Remains Sidelined Sunday
Jason Dickinson

a Game-Time Decision Sunday
Maxwell Crozier

to Replace Declan Carlile Sunday
Alexander Nikishin

Diagnosed With Concussion
Viktor Arvidsson

Exits Early Sunday
Theo Johnson

a Dynasty Faller After Busy Giants Offseason
Kyle Monangai

Remains a Dynasty Hold
Amon-Ra St. Brown

Remains a Locked-in Dynasty Stud
Jonah Coleman

Could Have Immediate Impact as Broncos' Short-Yardage Back
Jerry Jeudy

Browns Say Jerry Jeudy Will Not Be Impacted by Rookies
Logan O'Hoppe

Placed on 10-Day Injured List Due to Left-Wrist Fracture
Denny Hamlin

Is Denny Hamlin Worth Rostering for Talladega?
Xavier Worthy

a Buy-Low Candidate for Dynasty Managers Following NFL Draft?
NASCAR

Is Bubba Wallace Playable in Talladega DFS Lineups?
Skyler Bell

Earning Comparisons to Elite NFL Wideout Following NFL Draft
Jayden Daniels

' Supporting Cast in Washington Remains Similar Following NFL Draft
Joe Burrow

Dynasty Value Remains Impacted by Injury Concerns
Josh Naylor

Absent on Sunday With Quad Tightness
Andrei Iosivas

Facing New Competition for Bengals' WR3 Role After NFL Draft
Ryan Helsley

Returns From Bereavement List on Sunday
Steven Kwan

Back in Sunday's Lineup
Brent Rooker

Activated and Starting on Sunday Against Rangers
Roman Anthony

Returns as DH on Sunday
Tyler Reddick

Stay Away From Tyler Reddick at Talladega
Ryan Blaney

Can Ryan Blaney Shake Off The Bad Luck at Talladega?
Austin Cindric

Could Contend For Another Talladega Win
Kyle Busch

an Easy DFS Pick at Talladega
Ricky Stenhouse Jr

. a High-Risk, High-Reward Pick at Talladega
Todd Gilliland

a Sleeper to Watch at Talladega
Brad Keselowski

Is Brad Keselowski Worth Rostering for Talladega Lineups?
Chase Briscoe

Could Chase Briscoe be A Sneaky Tournament Play for Talladega Lineups?
Christopher Bell

Should DFS Managers Trust Christopher Bell at Talladega?
Ty Gibbs

Is A DFS Risk for Talladega Lineups
Arturs Silovs

Steps in and Saves Pittsburgh on Saturday
Sidney Crosby

Helps Lead Pittsburgh to Road Win Over Philadelphia
Brock Faber

a Huge Factor in Minnesota's Overtime Victory
Matt Boldy

Evens Series Between Minnesota and Dallas in Big Way
Frederik Andersen

a Game-Changer as Carolina Closes Out Ottawa
Logan Stankoven

Scores Yet Again as Carolina Sweeps Ottawa
Desmond Bane

Nails Seven Triples En Route to 25 Points
Boston Red Sox

Red Sox Fire Manager Alex Cora and Other Coaches
Josh Manson

Not Expected to Play Sunday
Mason Lohrei

Set to Miss Game 4 as Healthy Scratch
Steven Kwan

Scratched With Neck Stiffness
Trey Yesavage

Returning From Injured List on Tuesday
Eugenio Suárez

Eugenio Suarez Heading to the Injured List With Oblique Strain
MLB

Saturday's Mets-Rockies Game Postponed Due to Weather
Giancarlo Stanton

Exits With Leg Tightness on Friday
Eugenio Suárez

Eugenio Suarez Scratched on Friday With Mid-Back Pain
Jackson Holliday

Receives Positive Test Results, Will be Shut Down for a Week
Jeff Hoffman

Out as Blue Jays Closer
Youssef Zalal

Set For UFC Vegas 116 Main Event
Aljamain Sterling

An Underdog At UFC Vegas 116
Joselyne Edwards

Set For UFC Vegas 116 Co-Main Event
Norma Dumont

Looks To Extend Her Win Streak
Alexander Hernandez

A Favorite At UFC Vegas 116
Rafa Garcia

Looks For His Third Consecutive Win
Adrian Luna Martinetti

Set For His UFC Debut
Davey Grant

Looks To Get Back In The Win Column
Francisco Lindor

Expected to Miss "Significant Time"
Francisco Lindor

Mets Officially Place Francisco Lindor on Injured List With Calf Strain
Michael Harris II

Removed Early With Quad Tightness
Francisco Lindor

Likely Headed to the Injured List
Michael Harris II

Continues to Heat Up With Two-Homer Game on Wednesday
CFB

Beau Pribula Leading Virginia Quarterback Competition
Marco Penge

Trending Down Entering Zurich Classic
Sahith Theegala

Eyes Another Strong Week at Zurich Classic
Brooks Koepka

Shane Lowry Teams Up with Brooks Koepka at Zurich Classic
Si Woo Kim

Adds Another Strong Finish at RBC Heritage
Luke Clanton

Hoping to Find Form in New Orleans
Scottie Scheffler

is Starting to Hit His Stride
Brooks Koepka

Looking for Progress in PGA Return With Partner at Zurich Classic
Matt Fitzpatrick

Looks to Share Recent Form at Zurich Classic
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF