👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


Thursday Night Football DFS Lineup Picks for FanDuel, DraftKings - Colts vs. Titans

Jorge's top NFL DFS lineup picks for FanDuel, DraftKings and Week 10's Thursday Night Football Colts vs. Titans matchup. His daily fantasy football advice and value plays.

Week 10 kicks off on Thursday night with a big-time game that features the top two teams in the AFC South. The Indianapolis Colts will travel south to Nashville to take on the Tennessee Titans. This game has an under/over of 50.5 with the Titans being favored by 2.5 points.

In this article, I will be providing you with daily fantasy football picks on FanDuel and DraftKings for the Thursday Night Football slate on November 12th (Week 10). These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on both DraftKings and FanDuel.

If you have any questions you can follow me on Twitter @jorgepucks and fire away, or sign up for a premium RotoBaller NFL package and chat with myself and other NFL DFS analysts any time you'd like!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DFS Quarterbacks

Picking the right quarterback on this slate will be vital ofr both cash games and tournament lineups. Philip Rivers has been pretty average all year long and despite having big-time games against Cincinnati and Detroit, he has been relatively quiet all season long. Rivers is averaging 260 passing yards per game and has thrown 10 touchdowns while also throwing 7 interceptions. Rivers is not putting up the typical fantasy points that we have grown accustomed to in the past but part of that is due to the new offensive scheme with the Colts and how much they lean on the ground game. The Titans Defense has struggled to defend the pass as they are allowing 284 passing yards per game and with them only generating 10 total sacks on the season, this makes Rivers viable on this slate.

Ryan Tannehill has been playing great this season but he does draw the tougher matchup as the Colts have one of the best defenses in the league. They allow only 223 passing yards per game and limit opponents to just 18.3 points per game. Tannehill is averaging 247 passing yards per game and has a 19:3 touchdown to interception ratio which is very good. He has scored double-digit points in every game this year and is averaging 22.1 DK points per game. The Titans offense runs through Derrick Henry but if the Colts do a great job bottling up the ground game, the Titans might have to rely on the arm of Tannehill to pull this game out.

Analysis: Both quarterbacks are viable in all options with Rivers carrying more of the risk. Tannehill is the safer quarterback option and would be preferred in cash games but the matchup itself is a lot tougher.

 

DFS Running Backs

The running back position will be a key position on this showdown slate. Derrick Henry is the best back option in the whole game but draws a very tough challenge as the Colts Defense ranks third in the entire league against the run as they only allow 83.6 yards per game on the ground. The Titans are committed to grinding games out with Henry as he has seen over 20+ attempts in three out of his last four games played. Henry has seen most of the rushing workload as he tales roughly 84% of the all rushing attempts for this Tennessee offense and leads the way with eight rushing touchdowns. Henry is grinding out 105 yards per game and has an average of 92.5 rushing yards per game over his last four games against the Colts. Backing up Henry are D'Onta Foreman and Jeremy McNichols but due to the lack of playing time and attempts, it is truly a one-man show in Tennessee with Henry.

The running back situation in Indianapolis isn't quite as clear as the Titans. Once Marlon Mack went down with a season-ending injury, Jonathan Taylor took over the lead back duties but has struggled to really produce like a top back in the league. Taylor is averaging 52 yards on the ground and leads the team with four rushing touchdowns but has conceded rushing attempts to Jordan Wilkins and Nyheim Hines over the last two games. Wilkins has taken 31 rushing attempts to Taylors's 17 attempts over the last two games and it seems as if this could end up being more of a running back by committee approach in the second half of the season. Nyheim Hines is also involved in the Colt's gameplan as he is a threat catching passes out of the backfield and is looked at as a safety blanket for Rivers in passing situations. Hines leads this backfield in catches and has three receiving touchdowns so if the Colts fall behind early on in the game, Hines could be one that sees an uptick in playing time. The Titans are allowing 119 rushing yards per game which rank 17th in the league so if Taylor and Wilkins get going early on, this could be a night where we see one of them go off!

Analysis: Henry is a lock for cash games but does draw a tough matchup against a stingy Colts D. Taylor still looks to be the best Colts running back option but with the loss of touches over the past several weeks, it leads to us thinking that he will see more limited opportunities and makes all Colts running backs viable for tournaments.

 

DFS Wide Receivers

The colts wide receiving group is a tad bit messy right now, partly due to injuries and the overall offensive scheme. Rivers is involving running backs and tight ends in the passing game which is hindering the upside from his receivers. T.Y. Hilton is still the top receiver to account for in this offense as he holds a 13.9% target share but is barely seeing over five targets per game. Zach Pascal is right behind Hilton with a 12.1% target share and has seen the most targets on the season of all of the wide receivers (40). He leads the Colts receivers with 24 catches on the season and also leads the receiver group with two receiving touchdowns on the season. Marcus Johnson and Michael Pittman Jr. saw increased targets last week with Hilton being out but with Hilton returning for this game, they could see a small decrease in targets.

The Titans offense is pretty straight forward with A.J. Brown and Corey Davis leading the way for their receiving group. They both carry a 15.3% target share in the offense with Davis leading the receiving group with 29 catches on the season while Brown leads the team in targets with 48. Brown has been the big-play receiver in this Titans offense as he leads the offense with five receiving touchdowns and should always be looked at in all formats. Slot receiver Adam Humphries is out with a concussion so this opens up opportunities and targets for both Kalif Raymond and Cameron Batson. The Colts defense will focus on stopping the ground game with Henry which will give one-on-one opportunities outside for both Brown and Davis so they both have good upside in this matchup.

Analysis: Brown and Davis are the top receiving options on this slate based on targets and consistent volume so they should be considered in all formats. Hilton is healthy and looks to be good to go so he could also be looked at for all formats but does carry some risk as the Colts spread the ball around to many different weapons. Pascal offers high upside out of the remaining receivers while Pittman, Johnson, Raymond, and Batson are all value tournament plays.

 

DFS Tight Ends

There are plenty of tight end options on this showdown slate that are all in play. The Titans have really relied on Jonnu Smith as being a prime red-zone target in this offense as he has hauled in five receiving touchdowns on the season. He holds 13.7% of the team's target share and leads all Titan tight ends with 37 targets and 22 receptions. Smith is one that Tannehill relies on (especially when healthy) and is one of the safer options on the slate. Behind Smith is Anthony Firkser who also is carving out a role in this Titans offense. He has seen 31 total targets on the season and has 21 receptions which is only one catch behind Smith. While he doesn't have the red zone numbers, he has also become a reliable target to Tannehill who could go overlooked on this showdown slate.

The Colts have a very strong tight end room and it might be the best collective receiving trio in the league. Jack Doyle, Mo Alie-Cox, and Trey Burton make up this receiving tandem and they all carry some sort of receiving upside. Over the last five games played, Burton leads the group with 24 targets and holds a 7% target share. Cox and Doyle both have two touchdown receptions on the season but have seen a slight drop in targets once Burton was healthy and ready to go. Doyle is listed as out with a concussion which eliminates some confusion at the tight end role for the Colts and narrows down our focus to Burton and Cox. Cox is listed as questionable with a knee injury but was a full participant at practice so we can anticipate him being ready and good to go for tonight's game.

Analysis: Smith and Burton seem to be the best options at this position and could be viable cash game targets. Cox and Firkser are all involved in the offense and play slightly smaller roles ao this could be an area that helps differentiate your lineups in tournaments.

 

DFS Defense/Special Teams

The defenses could be a big key to this game. The Colts come in as a top defense in the entire league as they rank in the top three in both defending the pass and stopping the run and rank first overall in total yards allowed (307 yards allowed per game). They do a great job getting after the quarterback as they have racked up 20 sacks on the season and average 1.6 takeaways per game. The Titans do a great job of retaining possession of the ball as they average less than one giveaway per game offensively so the Colts defense must generate some turnovers if they want to win. On the other side of this game, The Titans defense has struggled to defend the pass and the run as they rank 28th against the pass and 17th against the run. They are allowing 25 points per game and allow over 403 yards per game to opponents.  Their lack of generating a pass rush has hindered their defense despite forcing 14 turnovers in eight games. If they are able to apply pressure to Rivers throughout this game, they could force several turnovers which makes their defense fantasy viable. With this potentially being a field position battle, both Blankeship and Gostowski are fantasy viable. They are both averaging above 8 DK points per game and get plenty of field goal opportunities.

Analysis: It might be best to leave defenses off of your cash game builds but could be viable in tournament lineups with Tennessee being the preferred defensive option (high takeaway numbers vs. turnover-prone QB). Blankenship is the better kicker so he should be prioritized ahead of Gostowski in all formats.

 

Good luck, RotoBallers, and remember to mix it up and don't be afraid to be different in these large field GPPs!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




REAL-TIME FANTASY NEWS

Bryce Lance

a Perfect Fit in New Orleans?
Mike Washington Jr.

Can Mike Washington Jr. Force a Backfield Split in Vegas?
Paul Reed

Makes Big Impact Off the Bench Wednesday
Adonai Mitchell

Unlikely to be Phased Out of Jets Offense
Daniss Jenkins

Contributes 19 Points As Starter
Cade Cunningham

Tallies 39 Points in Losing Effort
Tony Pollard

an Affordable Add for Contending Dynasty Managers
Max Strus

Notches 20 Points With Six Triples
Evan Mobley

Close to Triple-Double Wednesday
Mason Taylor

How Much Dynasty Value Will Mason Taylor Hold After Offensive-Heavy Draft?
Jarrett Allen

Records Double-Double in Game 5 Win
De'Von Achane

a Dynasty Cornerstone
James Harden

Leads the Way for Cavaliers in Game 5 Victory
Quinn Hughes

Finishes Postseason With 15 Points
Matt Boldy

Posts Two Assists in Season-Ending Loss
Scott Wedgewood

Perfect in Relief Effort
Martin Necas

Records Another Multi-Point Game
Brett Kulak

Sends Avalanche Into Conference Finals
Brayden McNabb

Suspended for One Game
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
Juan Soto

Exits Wednesday's Game Early with Ankle Injury
Tim Patrick

Jets Agree to Terms With Veteran Receiver Tim Patrick
Malik Nabers

Undergoes Second Knee Surgery
De'Von Achane

Dolphins, De'Von Achane Agree to Four-Year Contract Extension
Kevin Huerter

is Cleared to Return for Game 5
Caris LeVert

is Available for Game 5 on Wednesday
Duncan Robinson

is Out for Game 5
Keegan Murray

Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Sam Malinski

Set to Miss Second Straight Game
Artturi Lehkonen

Unlikely to Play Wednesday
Matthew Schaefer

Wins Calder Trophy
TOR

Maple Leafs Fire Head Coach Craig Berube
Jalen Hurts

Can Jalen Hurts Bounce Back as a Rusher in 2026?
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Zach Charbonnet

Dynasty Value in Question Entering 2026
DeVonta Smith

Poised to Reach a New Level of Production in 2026?
Chris Olave

Facing Increased Target Competition in New Orleans Entering 2026
Chris Bell

Dynasty Stock Rising Following NFL Draft
Ted Hurst

Facing Uphill Battle for Playing Time in Tampa Bay
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
Chris Brazzell II

Is Chris Brazzell II the Top Deep Threat in Carolina's Receiver Room?
Kaelon Black

a Threat to Win Backup RB Job in San Fran?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
De'Zhaun Stribling

to be 49ers' New "F" Receiver?
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
Drew Allar

Steelers "Uninstalling" Everything Drew Allar Learned in College
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Ja'Kobi Lane

Is Ja'Kobi Lane the Pass-Catching Answer the Ravens Have Been Seeking?
Zachariah Branch

Does Zachariah Branch Have a Path to Immediate Production?
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

Comes Alive in Game 5 Against Timberwolves
Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Victor Wembanyama

Leads Spurs to Big Win in Game 5
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Mason McTavish

Delivers Two Assists Tuesday Night
Pavel Dorofeyev

Pots Two Goals in Vital Game 5 Win
Josh Doan

Records Two Assists in Game 4 Victory
Evgeni Malkin

Penguins Want Evgeni Malkin Back
Sidney Crosby

Joins Team Canada for World Championship
Ryan Poehling

Suffers Upper-Body Injury in Game 5 Loss
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Charlie McAvoy

Slapped With Six-Game Suspension
Jonas Brodin

Unavailable for Game 5 Against Avalanche
Joel Eriksson Ek

to Remain Out Wednesday
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
Luis Castillo

Mariners Intend to Piggyback Luis Castillo, Bryce Miller
Logan Webb

Placed on 15-Day Injured List With Knee Bursitis
Bryce Miller

is Set to Return on Wednesday
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF