November 10, 2025
The Arizona Cardinals will place wide receiver
Zay Jones (Achilles) on Injured Reserve with an Achilles injury that he suffered in the Week 10 blowout loss to the Seattle Seahawks on Sunday, according to Zach Gershman of AZCardinals.com. Jones wasn't really on the fantasy radar to begin with in standard-sized leagues, but now he'll be forced to miss at least the next four games for the Cardinals. The 30-year-old veteran pass-catcher had only 12 catches on 18 targets for 183 yards and no touchdowns through eight games this year in a struggling Cardinals passing game. With Jones out for the foreseeable future,
Greg Dortch should see more targets, but he's only worth a waiver-wire pickup for WR depth in deeper leagues. The earliest that Jones will be able to return will be for a Week 15 matchup on Sunday, Dec. 14, against the Houston Texans on the road.
--Keith HernandezSource: AZCardinals.com - Zach Gershman
November 10, 2025
Green Bay Packers rookie first-round wide receiver
Matthew Golden (shoulder), who was listed as questionable to play on Monday night against the Philadelphia Eagles, is not expected to play, a source tells Tom Pelissero of NFL Network. Golden was pushing to go, but the Packers will rely on others to step up in the passing game without him. Green Bay will also be missing tight end
Tucker Kraft (knee), who suffered a season-ending torn ACL last week. The 22-year-old Golden was unable to practice with the team on Friday or Saturday. His next chance to return will come in Week 11 against the New York Giants on the road.
Dontayvion Wicks (calf) and
Savion Williams (foot) are also listed as questionable for Monday night, so
Romeo Doubs,
Christian Watson, and
Malik Heath could operate as the Packers' top three receivers against Philly, with tight end
Luke Musgrave also seeing an expanded role.
--Keith HernandezSource: NFL Network - Tom Pelissero
November 10, 2025
Baltimore Ravens head coach John Harbaugh said on Monday that cornerback Marlon Humphrey (finger) could need surgery on his finger, which would sideline him for a week or two, according to The Athletic's Jeff Zrebiec. The 29-year-old slot cornerback suffered the finger injury in Sunday's Week 10 win over the Minnesota Vikings. If Humphrey is forced to go under the knife, he'll be forced to miss this weekend's divisional game against the Cleveland Browns and probably the Week 12 game against the New York Jets as well. It's bad news for a Ravens defense that has gotten healthier in recent weeks after a tough start to the year, but the good news is Humphrey won't miss much time either way. In his ninth year with the Ravens, Humphrey has recorded 33 tackles (26 solo), an interception, five pass breakups, a forced fumble, and a fumble recovery in his eight starts.
--Keith HernandezSource: The Athletic - Jeff Zrebiec
November 10, 2025
Houston Texans running back
Joe Mixon (ankle, foot) hasn't been able to do anything for the last four months with what the team is calling a foot injury, and there have been no recent updates on what his timetable might look like for a return this year. It has opened up speculation that Mixon won't return at all for Houston in 2025. He was placed on the Non-Football Injury list in the offseason, and the Texans have offered few details on his foot injury. General manager Nick Caserio said in early October that Mixon was making progress, but the fact that we haven't heard anything since isn't good news. The Texans are still holding out hope that Mixon will be back this year, but KPRC 2 Sports' Aaron Wilson has said that Mixon's situation is "tough" and "complicated." Fantasy managers shouldn't be so hopeful he'll play in 2025. In the meantime, the Texans will roll on with veteran
Nick Chubb in the early down role, with rookie
Woody Marks seeing passing-down work.
--Keith HernandezSource: Pro Football Reference
November 10, 2025
The San Francisco 49ers are still in wait-and-see mode with quarterback
Brock Purdy (toe) as they head into a Week 11 divisional matchup against the Arizona Cardinals, according to Matt Barrows of The Athletic. Purdy has not played since aggravating his turf-toe injury in the Week 4 loss to the Jacksonville Jaguars, but he's been practicing on a limited basis, and head coach Kyle Shanahan said on Monday that the team is looking for the 25-year-old signal-caller to increase his activity this week. The 49ers "want three aggressive practices [from him], and we want to hear from him and make sure he feels good after them, too." The Niners are hoping Purdy can finally return to face the Arizona Cardinals in Week 11, but he'll only be cleared if he can upgrade to a full practice and avoid any setbacks. When Purdy returns to the starting role under center, he'll have immediate low-end QB1 upside, but fantasy managers will also be wary of any potential rust from his long layoff.
UPDATE: ESPN's Nick Wagoner thinks "it's clear the 49ers don't intend to make Purdy active again until he's healthy enough to reclaim his starting job."--Keith HernandezSource: The Athletic - Matt Barrows
November 10, 2025
The San Francisco 49ers are hoping to get wide receiver
Ricky Pearsall (knee) back at practice this week, according to Matt Barrows of The Athletic. The 49ers have been hopeful of getting Pearsall back from a PCL sprain that he suffered back in the Week 4 loss against the Jacksonville Jaguars for several weeks now, but it has not happened. The 25-year-old former first-rounder has not practiced or played since injuring his right knee, and even if he's able to get back onto the practice field this week, it doesn't mean he'll be active on Sunday for a Week 11 divisional matchup against the Arizona Cardinals. "Hopefully the next two days go good, and if they do, he'll be back out there. He had a good weekend," head coach Kyle Shanahan said. The Niners have been without both Pearsall and quarterback
Brock Purdy (toe) since Week 4. When Pearsall does return, he could be the No. 3 target in the passing game behind
Jauan Jennings and tight end
George Kittle.
--Keith HernandezSource: The Athletic - Matt Barrows
November 10, 2025
New York Jets wide receiver
Garrett Wilson (knee) is expected to miss at least three to four weeks with a knee sprain that he suffered in Sunday's Week 10 victory over the Cleveland Browns, a source told Rich Cimini of ESPN. However, the good news is that Wilson won't require surgery. Wilson hyperextended his knee against the Denver Broncos on Oct. 12 in London and missed two games before returning to action on Sunday against Cleveland, only to suffer a setback with a knee sprain. The 25-year-old WR1 will now miss additional time, with fantasy managers now hoping he can return to contribute if they make the fantasy postseason (normally from Weeks 15-17). It's bad news for Wilson and the Jets' passing game, which has been the worst in football this year, averaging a league-low 148.8 passing yards per game. The Jets will ask
Arian Smith,
Tyler Johnson,
John Metchie III, and
Adonai Mitchell, among others, to step up with Wilson sidelined. None of those options is particularly intriguing for fantasy managers going forward. Running back
Breece Hall led the Jets in receiving in Week 10 with a 42-yard reception that went for a touchdown.
--Keith HernandezSource: ESPN New York - Rich Cimini
November 10, 2025
Los Angeles Chargers wide receiver
Keenan Allen caught two passes for 19 yards on five targets in Sunday's 25-10 win over the Pittsburgh Steelers. It was a quiet night statistically, but a historic one: Allen passed Hall of Famer Antonio Gates to become the Chargers' all-time leader in receptions. Unfortunately, the 33-year-old's route rate continues to decline (around 60%) as younger receivers like rookie Tre' Harris are integrated into the offense. His decrease in volume is typical of aging veterans mid to late in the season. Still, Week 11 offers a bounce-back opportunity against a struggling Jacksonville Jaguars defense that ranks ninth in passing yards allowed and fourth in receiving touchdowns surrendered. If rookie tight end
Oronde Gadsden (quad) misses time, Allen could see an uptick in usage. He remains a WR3 with PPR upside, but if he continues to struggle to see volume, he might become more of a fringe WR4 moving forward.
--Don FanelliSource: NFL
November 10, 2025
Los Angeles Chargers quarterback
Justin Herbert threw for 220 yards and one touchdown, while rushing five times for 19 yards in Sunday night's win over the Pittsburgh Steelers. It was another gritty performance as he continued to play behind a severely depleted offensive line. Herbert was sacked five times and took numerous hits, which led him to tape both ankles during the game. The Chargers relied more on their ground game, helping to reduce some of the pressure throughout the night. Looking ahead to Week 11, Herbert faces a Jacksonville Jaguars defense that ranks second in interceptions (12) but has also allowed the fourth-most passing touchdowns. Jacksonville's secondary is opportunistic yet inconsistent, offering Herbert a potential rebound opportunity... if the offensive line can hold up. Keep an eye on his ankle health throughout the week, but expect mid-tier QB1 production if he's fully healthy.
--Don FanelliSource: NFL
November 10, 2025
Los Angeles Chargers wide receiver
Quentin Johnston led the team with 10 targets on Sunday night, catching five passes for 42 yards in the 25-10 victory over the Pittsburgh Steelers. Although his stat line wasn't eye-popping, the volume is encouraging. His longest catch was only 15 yards, as a heavily pressured
Justin Herbert mainly relied on quick throws behind a battered offensive line all night. In Week 11, Johnston faces a favorable matchup against the Jacksonville Jaguars, who have allowed the ninth-most passing yards and the fourth-most receiving touchdowns this season. They have also given up 31 receptions of 20 yards or more, which could benefit Johnston. With rookie tight end
Oronde Gadsden (quad) day-to-day, Johnston could see more red-zone and deep-shot targets. He remains a boom-or-bust WR3/FLEX option with upside in this matchup.
--Don FanelliSource: NFL
November 10, 2025
Kansas City Chiefs head coach Andy Reid "nudged" that running back
Isiah Pacheco (knee) may take more time and might not be ready to return coming out of the bye to face the division-rival Denver Broncos in Week 11, according to Pete Sweeney of Arrowhead Pride. Pacheco sat out of the Week 9 loss to the Buffalo Bills, but at the time, he was expected to be ready to go coming out of the Chiefs' Week 10 bye. The 26-year-old isn't dealing with a serious injury, but KC might just want to play it safe to ensure that they'll have Pacheco at full speed for the final stretch of the regular season. If Pacheco misses a second straight game, veteran
Kareem Hunt should once again handle the bulk of the backfield work, with rookie
Brashard Smith and
Clyde Edwards-Helaire battling for change-of-pace snaps. After playing in only seven regular-season games in 2024 due to injury, Pacheco has disappointed again in 2025, rushing for 329 yards and only one touchdown on 78 carries through eight starts.
--Keith HernandezSource: Arrowhead Pride - Pete Sweeney
November 10, 2025
Washington Commanders head coach Dan Quinn said on Monday that he will take over as the team's defensive coordinator, starting in Week 11 against the Miami Dolphins in Madrid, Spain, according to JP Finlay of NBC Sports Washington. Quinn said that defensive coordinator Joe Whitt "took the news like a pro." The Commanders will make the move after surrendering 44 points to the Detroit Lions in the Week 10 blowout loss. Washington has now lost five straight games, with the last four of them coming by a margin of 20-plus points. Through 10 weeks in 2025, the Commanders defense just hasn't been able to slow anybody down, allowing 28 points per game, the fourth-most in the NFL. Injuries haven't been kind to that side of the ball, either.
--Keith HernandezSource: NBC Sports Washington - JP Finlay
November 10, 2025
Los Angeles Rams head coach Sean McVay said on Monday that rookie
Harrison Mevis will be the team's kicker again for a Week 11 divisional showdown against the Seattle Seahawks, according to Gary Klein of the Los Angeles Times. The Rams made the switch to Mevis over the struggling
Joshua Karty in their Week 10 win over the San Francisco 49ers. The 23-year-old wasn't tested with any field-goal tries on Sunday, but he did make all six of his extra-point opportunities for the Rams. Karty remains on the team's 53-man roster, so Mevis will need to perform to stick around. Mevis lacks experience, but he could quickly become a fantasy consideration at the kicking position if he's successful in one of the best offenses in football.
--Keith HernandezSource: Los Angeles Times - Gary Klein
November 10, 2025
Buffalo Bills tight end
Dalton Kincaid (hamstring) is considered week-to-week with the hamstring injury that he suffered in Sunday's upset loss to the Miami Dolphins, sources told Jordan Schultz of FOX Sports. Kincaid has been one of the team's top targets this year, catching 29 passes for 448 yards and a team-high four touchdowns, so losing him for any amount of time would be bad news for the slumping Bills. Before getting hurt in Week 10, the 26-year-old caught two of his three targets for 37 yards. Fellow TE
Dawson Knox caught three of his four targets for a season-high 37 yards against Miami with Kincaid injured, and he'll be in play as a touchdown-dependent TE2 streamer in Week 11 against the Tampa Bay Buccaneers if Kincaid is unable to play. Fantasy managers should consider Kincaid a highly volatile option for Week 11. Check back later this week to see if he's able to practice.
--Keith HernandezSource: FOX Sports - Jordan Schultz
November 10, 2025
Los Angeles Chargers rookie tight end
Oronde Gadsden (quadriceps) is considered "day-to-day" after an MRI exam on Monday revealed a quad bruise, a source told Adam Schefter of ESPN. Gadsden injured his quad in the third quarter of Sunday night's win over the Pittsburgh Steelers and never returned with the game already well in hand. The 22-year-old's injury doesn't sound very serious, but fantasy managers will need to keep a close eye on his practice status heading into Sunday's Week 11 tilt on the road against the Jacksonville Jaguars. If Gadsden isn't cleared to play this weekend, both
Will Dissly, who was a healthy scratch on Sunday night, and
Tyler Conklin would see additional opportunities in the passing game. Gadsden has quickly emerged in his first NFL season and has been on the low-end TE1 radar in fantasy football, catching 35 passes for 466 yards and two touchdowns in his first eight games.
--Keith HernandezSource: ESPN - Adam Schefter
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