November 8, 2025
Jacksonville Jaguars running back
Travis Etienne Jr. has been a solid fantasy starter this season, which should continue in Week 10. The Houston Texans serve as a somewhat difficult matchup, but are more difficult for passing offenses than rushing offenses. With quite a few receiving options banged heading into this week, the Jaguars could decide to lean on the run game more. Etienne Jr. is coming off a 22 carry, five reception game with 115 total yards against the Las Vegas Raiders. That potential volume gives the Clemson product a solid fantasy floor. Fantasy managers should feel fine starting Etienne Jr. in one of their RB slots against the Texans in Week 10.
--Seth Quinn - RotoBaller
November 8, 2025
Jacksonville Jaguars running back
Bhayshul Tuten has a small chance to be more involved, but is still a risky start in Week 10. The receiving core for the Jaguars is currently banged up, which led them to rely on the run game more last week. That led Tuten to get 10 total touches and find the end zone, but he only produced 28 total yards. The rookie should be involved again against a top defense that’s especially strong against the pass, making him seem like a potentially decent option. However, the floor is very low given his backup status to
Travis Etienne Jr. He should be involved in the game plan, but Tuten is still better left on benches in Week 10.
--Seth Quinn - RotoBaller
November 8, 2025
Buffalo Bills running back
James Cook has been removed from the injury report and will play Sunday against the Miami Dolphins, presumably without any limitations. This is great news for Cook and his fantasy managers, as a matchup against the Dolphins provides an enormous opportunity for the 26-year-old to rack up fantasy points. Miami has been miserable against the run this year, surrendering the third-most rushing yards and fifth-most fantasy points to opposing running backs in 2025. Cook is the overall RB7 in PPR leagues so far with 867 rushing yards, 100 receiving yards, and seven touchdowns. In his last outing against Miami, he accrued 118 scrimmage yards and one touchdown. Fantasy managers should have full confidence deploying Cook as a mid-to-high RB1 this week.
--Andersen PickardSource: RotoBaller
November 8, 2025
The Jacksonville Jaguars defense/special teams unit has a plus matchup in Week 10 against the Houston Texans. The Houston offense has been inconsistent this season, but with Davis Mills starting at QB, things may get even more difficult for them. That is great news for the Jaguars, who currently sit third in the NFL in takeaways. The only menacing threat to the Jaguars defense is Nico Collins, so as long as they can corral him, they should be in line for multiple sacks and turnovers. Fantasy managers should be starting the Jaguars D/ST unit with confidence in Week 10.
--Seth Quinn - RotoBaller
November 8, 2025
The Carolina Panthers defense/special teams unit should be started in most fantasy leagues ahead of their Week 10 matchup against the New Orleans Saints. While the Panthers' defense has ranked below league-average in terms of fantasy production through the first nine weeks of the season, they're a must-start unit with a great opportunity to get right against the Saints on Sunday. New Orleans has allowed the second-most fantasy points to opposing D/ST units, and
Tyler Shough threw an interception with just 176 passing yards last week. Meanwhile, Carolina has momentum of its own, allowing just 13 points and forcing two turnovers in an impressive win over the Green Bay Packers last week. Managers should start the Panthers D/ST with confidence this week, even if it means picking them up off the waiver wire. After all, the unit ranks #3 in RotoBaller's Week 10 D/ST rankings for fantasy football.
--Andersen PickardSource: RotoBaller
November 8, 2025
Chicago Bears wide receiver
Olamide Zaccheaus is coming off his best game of the season, catching six of eight targets for 58 yards and a touchdown in the 47-42 win over Cincinnati. His expanded role came with
Cole Kmet and
Luther Burden III sidelined, but both are expected to return in Week 10 against the Giants. With Chicago's receiving corps back to full strength (plus 25 mph winds likely limiting the passing game), Zaccheaus is set to move back into a secondary role. Even with a favorable matchup, he should not be in fantasy lineups this week.
--Nathan HarveySource: Pro Football Reference
November 8, 2025
Washington Commanders running back
Jeremy McNichols has maintained a consistent role as the team's most trusted option on pass downs. McNichols has totaled 17 carries for 143 yards and a touchdown to go with 12 catches on 17 targets for 129 yards in nine games this season. The 29-year-old led Washington in receiving in their Week 8 loss at Kansas, catching five of his six targets for 64 yards, the second most in a game of his career. That was also his highest snap share in a game this season at 43.4%, but he's mostly been limited to late down responsibilities while rookie
Jacory Croskey-Merritt and
Chris Rodriguez Jr. handle the early down carries. In a Week 10 matchup where Washington is a sizable home underdog against the Lions, McNichols could be on the field more often in a negative game script. McNichols has some sneaky PPR value in deeper leagues on Sunday.
--Kyle McCarthySource: RotoBaller
November 8, 2025
Jacksonville Jaguars kicker
Cam Little’s stock is on the rise after nailing an NFL-record 68-yard field goal last week. However, with the Jaguars offense banged up, his long distance ability may not translate into enough opportunities for a big fantasy day. The Jaguars will be without
Brian Thomas Jr., so it will be even harder for them to move the ball against what is already a tough matchup to start with. In their previous matchup with the Texans this season, the Jaguars scored just 17 points with more healthy weapons, so it’s hard to see the upside with Little this week. However, he still should be viewed as a solid option given his big leg and solid floor this season. Little should be considered a low end starting kicker in Week 10.
--Seth Quinn - RotoBaller
November 8, 2025
Carolina Panthers wide receiver
Tetairoa McMillan (hamstring) is listed as questionable for Week 10 against the New Orleans Saints, and head coach Dave Canales acknowledged that he's concerned about the rookie's status. However, if McMillan does suit up on Sunday, he'll rank as a low-end WR2 and should be started in all fantasy leagues. The 22-year-old has found plenty of success in his first pro season, catching 41 passes for 558 yards and two touchdowns while ranking as the overall WR21 in PPR leagues. He's a high-volume target in an offense that passes the ball a decent amount; he had both a 100-yard game and a multi-touchdown game within the first six weeks of his NFL debut. McMillan is a strong WR2 option for the rest of the season, but as long as he's on the injury report, managers will need to confirm his availability 90 minutes before kickoff.
--Andersen PickardSource: RotoBaller
November 8, 2025
Chicago Bears kicker
Cairo Santos has been inconsistent this season, converting just 78% of his field goal attempts. He's seen plenty of recent volume, with him averaging 3.7 field goal attempts over his last three games. This season, Santos ranks as the No. 11 kicker in fantasy scoring on a per-game basis. However, Week 10 sets up poorly. With 25 mph winds and mid-30s temperatures expected in Chicago, kicking conditions will be difficult. Combine that with Ben Johnson's aggressive fourth-down tendencies, and Santos' opportunities could be limited. Fantasy managers should look elsewhere at kicker this week.
--Nathan HarveySource: Pro Football Reference
November 8, 2025
Jacksonville Jaguars quarterback
Trevor Lawrence may have a tough time in Week 10. The Jaguars face the Houston Texans, who have one of the top defenses in the NFL, and are especially strong against the pass. Combining that with a banged up receiving core, and you’ve got a recipe for a tough outing. However, Lawrence has shown capable of producing big fantasy games in tough matchups after a great rushing performance against the Kansas City Chiefs. He also rushed for two touchdowns last week, which could be a good way to still produce fantasy points in a tough situation this week. That makes Lawrence a capable starter in bigger leagues and superflex leagues in Week 10.
--Seth Quinn - RotoBaller
November 8, 2025
Chicago Bears rookie tight end
Colston Loveland is coming off a huge performance, posting 118 yards and two touchdowns in the 47-42 win over Cincinnati. The breakout game finally arrived for the 10th overall pick in the 2025 NFL Draft, beating his previous career high in yards by 80 yards. However, that surge came with veteran
Cole Kmet leaving early due to a concussion. Kmet is off the injury report and set to return for Week 10 against the Giants. On the season, Kmet has played 70% of the snaps compared to Loveland's 56%, and his presence has consistently capped Loveland's routes and target share. With Kmet back in the mix and 25+ mph winds expected to limit the passing game, Loveland is a strong candidate for regression this week.
--Nathan HarveySource: Pro Football Reference
November 8, 2025
Washington Commanders running back
Chris Rodriguez Jr. is coming off his best game of the season in Week 9 against the Seahawks and has been named a team captain for Sunday's matchup against the Detroit Lions. Rodriguez recorded a season-high 12 carries for 65 yards and his second touchdown of the season last week against Seattle and is expected to see more work in Week 10. The third-year back out of Kentucky has consistently run hard when given opportunities. Offensive coordinator Kliff Kingsbury praised Rodriguez when speaking with the media on Friday, saying, "We have to take what's blocked," and adding that Rodriguez "did a really nice job" of doing that and has "played at a high level" whenever the team has needed him to step up. The 25-year-old should be in line to at least split early down carries with rookie
Jacory Croskey-Merritt, with the potential to take on more if he continues to run well while veteran
Jeremy McNichols handles pass-down responsibilities. Rodriguez is in flex consideration in deeper leagues for Week 10 against the Detroit Lions.
--Kyle McCarthySource: RotoBaller
November 8, 2025
Atlanta Falcons wide receiver
Drake London is coming off his biggest game of the season, catching nine of his 14 targets for 118 yards and three touchdowns. After being held scoreless over the first three games of the season, he's now recorded a touchdown catch and gone over 100 yards receiving in three of his last four games, and now has four straight games with double-digit targets, which is the longest active streak in the NFL. The 24-year-old has seen his average depth of target (aDOT) go from 8.6 yards over the first three games of the season to 10.9 yards over his last four, and he'll take on a Colts defense in Week 10 that has been generous, yielding the ninth-most fantasy points per game to opposing wideouts, is allowing the fourth-most receiving yards per game over their last three games (268.7), and is allowing 24.5 points per game on the road compared to 16.6 PPG at home. He could see a lot of newly-acquired CB Sauce Gardner, but in what should be a high-scoring affair in Germany, London sets up as a top-five option at receiver in Week 10.
--Jarod RuppSource: ESPN
November 8, 2025
New York Giants running back
Devin Singletary's fantasy value is largely dependent on game flow, and he could split snaps with
Tyrone Tracy Jr. during Sunday's Week 10 contest against the Chicago Bears. Singletary handled 56 percent of the snaps last week, registering eight carries for 43 yards, plus an additional two catches and eight receiving yards. Offensive coordinator Mike Kafka recently confirmed that Tracy will earn the start in Week 10, but his comments indicated that the exact workload split is dependent on game flow. In other words, Singletary could pace the backfield in snaps, Tracy could lead the way, or we might see another 50-50 split. With uncertainty continuing to surround this backfield post-
Cam Skattebo (ankle) injury, fantasy managers should be wary of deploying Singletary as anything more than a low-end RB3/flex. He's merely a desperation option who can help managers short-term as their roster deals with bye weeks or injuries.
--Andersen PickardSource: RotoBaller
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