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Fantasy Aces DFS Advice: Week 13 NFL - Daily Fantasy Football Picks

Hey there Rotoballers! In this article I will be taking a look at some of my favorite FantasyAces DFS lineups plays for the Week 13 slate.

These picks are based on a multitude of factors including matchup, talent, recent performance, and pricing on Fantasy Aces. Let's get to the picks!

Editor's Note: New users that sign up on FantasyAces, make a $20 deposit, and enter any game will receive BOTH our full season NFL and NBA Premium Passes for free, a $119.99 value. Just email [email protected] with your new FantasyAces username - and boom, that's it! We will email you with your Premium Passes.

Be sure to check all of our fantasy football rankings for 2025:

 

Quarterback Plays for Fantasy Aces

Drew Brees (vs. DET, $7,850)

Brees is the clear-cut top quarterback option on this slate while also ranking as the most expensive. He will definitely be worth paying up for against Detroit. The Saints will be taking on a leaky Lions pass defense at home, where Brees has been absolutely dominant this season. New Orleans is coming off of hanging 49 points on the Rams last week and they very well could eclipse that number this weekend against Detroit. Brees' home numbers are exceptional this season, with him completing 71% of his passes for 2,142 yards, 19 touchdowns, and four interceptions...in six games!

Ryan Fitzpatrick (vs. IND, $5,700)

Fitzpatrick is a solid second quarterback on Aces this weekend and his low salary will help you shoehorn Drew Brees into those lineups. If Fitzpatrick was ever going to reclaim the (Fitz)magic he showed in 2015, it should come against the Colts. Indianapolis has one of the worst defenses in the league, ranking 30th in pass defense and 31st in run defense according to Football Outsiders' DVOA ratings. Fitzpatrick has been playing better as of late and was solid (save for an untimely fumble) against the Patriots last weekend, throwing for two touchdowns and 269 yards. Dollar for dollar, Fitzpatrick's salary is one of the best values for a quarterback on Fantasy Aces this weekend.

 

Running Back Plays for Fantasy Aces

LeSean McCoy (@ OAK, $5,700)

McCoy showed us last week that he doesn't need a fully healthy thumb to tear through opposing defenses. The Bills' star running back rolled up 103 yards and two touchdowns against the Jaguars. He draws an exceptional matchup against the Raiders this weekend in a game which has sneaky shootout potential. With Sammy Watkins experiencing foot pain after just one game back, there's a chance the Bills will have to deploy a run-heavy attack against an Oakland run defense that ranks just 27th in the league in DVOA. As he showed last week, McCoy has just as much upside as David Johnson and Le'Veon Bell, but he comes at a significantly cheaper price than they do. 

Jordan Howard (vs. SF, $5,300)

Jay Ajayi failed to cash in on a pristine matchup against a weak San Francisco run defense last week, but the multitude of injuries on Miami's offensive line surely had a hand in that. Don't let Ajayi's slow game play into your decision-making this weekend as Jordan Howard is a fantastic play. Howard has been leading the Chicago offense lately, racking up 414 yards and a touchdown over his past four games. He should retain his lead back role against a 49ers defense that is allowing the most fantasy points per game to opposing running backs this year.

 

Wide Receiver Plays for Fantasy Aces

Brandon Marshall (vs. IND, $4,900)

Marshall has worked through a rather disappointing second season with the Jets, mostly due to the poor quarterback play New York has seen. That being said, Marshall is coming off one of his most productive games since Week 5 and gets a great matchup against the Colts. Indianapolis' best defensive back, Vernon Davis, has been injured or ineffective for most of the season. That gives Marshall a significant advantage against a Colts pass defense which is ranked 30th in DVOA according to Football Outsiders. A Ryan Fitzpatrick/Marshall stack is worth having some exposure to on Fantasy Aces this weekend.

Larry Fitzgerald (vs. WAS, $4,850)

Fitzgerald is coming off a slow day where he saw just four targets, the least he's had all year. Look for the veteran to bounce back this week against a Washington pass defense which has been tough on outside receivers, but that can be beaten by receivers out of the slot. Josh Norman, Washington's best corner, doesn't usually venture into the slot, meaning he will likely spend most of his time squaring off against Michael Floyd and J.J. Nelson. Look for Fitzgerald to be primarily covered by Kendall Fuller, who has just a 50.8 grade on Pro Football Focus. Fitzgerald should be able to take advantage of this matchup for the Cardinals and should go back to being his normal productive self this weekend.

 

Tight End Play for Fantasy Aces

Eric Ebron (@ NO, $4,600)

This is a perfect spot to use Ebron after his goose egg disappointed daily players this past Thanksgiving. Detroit's tight end only saw one target against the Vikings, but on the year he's averaging 6.1 targets per game and should remain a big part of the Lions' offense in what will be a shootout against the Saints. New Orleans' pass defense is 21st in the league in DVOA against enemy tight ends, giving Ebron a favorable matchup this weekend.  

 

Defense/Special Teams Play for Fantasy Aces

Baltimore Ravens (vs. MIA, $3,000)

The Broncos, Patriots, and Ravens are all in really good spots this weekend, but the Ravens check in $400 cheaper on Aces, making them the preferred play. Miami has leaned extensively on the run game during their recent success but they could struggle to find room to run against the number one ranked run defense in the league. If the Ravens shut down Jay Ajayi and the Dolphins run game, as can be reasonably expected, then Miami will have to lean on Ryan Tannehill and the passing attack in attempts to win this game. We saw in the beginning of the season that this is not a recipe for success for the Fins. Miami has the third-lowest implied team total on the slate against a fearsome Ravens defense which is playing at home. Tee up the Ravens defense with confidence this weekend.




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REAL-TIME FANTASY NEWS

Brian Thomas Jr.

Limited in Practice on Wednesday
Jerami Grant

Available Wednesday Night
Jalen Brunson

Returns From Two-Game Absence
Jalen Smith

Available to Play Wednesday
Tre Jones

Downgraded to Out
Shaedon Sharpe

Misses Wednesday's Game
Dereck Lively II

Cleared for Action Wednesday
Daniel Gafford

Available Wednesday
Caleb Martin

Won't Play Against Knicks
Raisel Iglesias

Returning to the Braves on One-Year Deal
Lamar Jackson

Absent Due to Ankle Injury
Marvin Bagley III

Starts on Wednesday
Mike Conley

Joins Starting Unit Wednesday
Saddiq Bey

Cleared for Wednesday's Action
Zion Williamson

Returns to Action Wednesday
Aaron Gordon

Out Wednesday
Cooper Flagg

Won't Play Wednesday
Bam Adebayo

Cleared to Play Wednesday
Tre Mann

Ruled Out Wednesday
Sam Merrill

Ruled Out for Wednesday
Jabari Smith Jr.

Active Against Cavaliers
Buddy Hield

Good to Go Wednesday
Jonathan Kuminga

Misses Fourth Consecutive Game
Alexandre Sarr

Unavailable on Wednesday
Conor Garland

to Return on Thursday
Thomas Harley

to Miss Road Trip
Eetu Luostarinen

Out Week-to-Week After Barbecue Accident
Curtis Lazar

to Miss at Least Three Games
Vladimir Tarasenko

Misses Third Consecutive Game
Mikael Granlund

Remains Out Wednesday
Charlie McAvoy

Out Indefinitely After Facial Surgery
Joe Burrow

to Potentially Return in Week 12?
Aaron Rodgers

Out on Wednesday, Hopes to Practice Thursday
Jaylen Warren

Not Seen at Wednesday's Practice
Dak Prescott

Lands on Injury Report Ahead of Week 12 With Hip Injury
Rhamondre Stevenson

Targeting a Return in Week 12?
Isiah Pacheco

Returning to Practice on Wednesday
Brian Thomas Jr.

Jaguars "Optimistic" About Brian Thomas Jr.'s Week 12 Status
Josh Jacobs

Will Not Practice on Wednesday
Sahith Theegala

Looking to Continue Fall Run at RSM Classic
Jayden Daniels

Commanders Considering Shutting Down Jayden Daniels?
Stephan Jaeger

Looking to Bounce Back at RSM Classic
Tom Hoge

Looking to Regain Form at RSM Classic
Joe Highsmith

Searching for Turnaround at RSM Classic
Adam Hadwin

Looking to Build on T11 Finish in Bermuda
Austin Eckroat

Searching for Momentum at RSM Classic
Joel Dahmen

Trying to Find Form at the RSM Classic
Marvin Harrison Jr.

Ruled Out Again in Week 12
Drake London

Falcons Hoping That Drake London Will Return in Week 13
CFB

Garrett Nussmeier Doubtful to Play Against Western Kentucky
Michael Penix Jr.

Needs Reconstructive Surgery on Torn ACL
Jaxson Dart

Expected to Return to Practice on Wednesday
Shedeur Sanders

Will Start Against Raiders
Dalton Kincaid

Ruled Out Against Texans
Connor Bedard

Continues Tear With Hat Trick
Macklin Celebrini

Pots Hat Trick in Tuesday's Win
Jake Guentzel

Records Eighth Career Hat Trick
Sammy Blais

Injured Versus Blues
Alexander Romanov

Injured in Tuesday's Win
Ryan Hartman

Considered Week-to-Week
Michael Thorbjornsen

Hopes to End 2025 Campaign With Another Solid Finish
Andrew Novak

Looks to End 2025 Season on High Note at RSM Classic
Harry Higgs

Teetering for PGA Tour Card in 2026
PGA

Nico Echavarria has the Potential to Contend at the RSM Classic
Sam Stevens

Finishing Out Year in Georgia
Seamus Power

Playing Better at the Right Time
Beau Hossler

Roller Coaster Comes to Saint Simons Island
Quade Cummins

The Time is Now for Quade Cummins in Georgia
Austin Cook

Needs a Win at the RSM Classic
Cameron Champ

on the PGA Tour Card Bubble
Grayson Rodriguez

Shipped to Angels
Taylor Ward

Orioles Acquire Taylor Ward From Angels
Shota Imanaga

Accepts Cubs Qualifying Offer
Brandon Woodruff

Returning to Milwaukee in 2026
Denny McCarthy

Looking For Another Solid Finish at RSM Classic
Si Woo Kim

Looking To Use Current Momentum to Flip Script at RSM Classic
Mackenzie Hughes

a Good Bounce-Back Candidate at RSM Classic
Harris English

Making 14th Start at This Week's RSM Classic
Konnor Griffin

Could Compete for Starting Shortstop Job in 2026
Gleyber Torres

Accepts Tigers Qualifying Offer
Odell Beckham Jr.

Officially Reinstated by NFL Commissioner
Matt Murray

to Miss Six Weeks With Lower-Body Injury
Ilya Lyubushkin

Out on Tuesday
Jamie Benn

Makes Season Debut Tuesday
Evgenii Dadonov

on Track to Return Tuesday
Dougie Hamilton

a Game-Time Call Tuesday
Anthony Cirelli

Expected to Return Against Devils
Victor Hedman

Questionable for Tuesday
Auston Matthews

to Miss at Least Two More Games
C.J. Stroud

Expected to Return in Week 13 Against Colts
C.J. Stroud

to Miss Another Game
Joe Mixon

Uncertainty Remains Around Joe Mixon's Return Timeline
CFB

Sam Leavitt Set to Enter Transfer Portal?
Jose Altuve

Undergoes Foot Surgery
Alex Bregman

Red Sox Going for Either Alex Bregman or Pete Alonso?
CFB

James Franklin to be Virginia Tech's Next Head Coach
CFB

Fernando Mendoza the Clear Heisman Trophy Favorite?
CFB

Beau Pribula Has Chance to Face Oklahoma on Saturday
Jack Della Maddalena

Gets Dominated
Islam Makhachev

Claims UFC Welterweight Belt
Zhang Weili

Gets Outclassed
Valentina Shevchenko

Wins Unanimous Decision At UFC 322
Sean Brady

Suffers First-Round TKO Loss
Michael Morales

Remains Unbeaten
Leon Edwards

Suffers Second-Round Knockout Loss
Leon Edwards

Carlos Prates Becomes The First Man To Knock Out Leon Edwards
Beneil Dariush

Suffers Brutal First-Round Knockout Loss
Beneil Dariush

Benoit Saint Denis Knocks Out Beneil Dariush In 16 Seconds
Josh Naylor

Mariners Finalizing Five-Year Contract
CFB

Jeremiah Smith, Carnell Tate Not Dealing With Long-Term Injuries
CFB

Virginia Tech Close To Naming James Franklin As Head Coach
CFB

Garrett Nussmeier Doubtful vs. Arkansas On Saturday
Edwin Díaz

Blue Jays Interested in Signing Edwin Diaz?
Jacob deGrom

Named AL Comeback Player of the Year
Ronald Acuña Jr.

Ronald Acuna Jr. Wins NL Comeback Player of the Year Award
Aroldis Chapman

Named AL Reliever of the Year
Edwin Díaz

Edwin Diaz Named NL Reliever of the Year
Islam Makhachev

Set For UFC 322 Main Event
Jack Della Maddalena

Set For His First Title Defense
Zhang Weili

Can Become The New Women's Flyweight Champion
Valentina Shevchenko

Set For UFC 322 Co-Main Event
Michael Morales

Looks To Remain Undefeated
CFB

Mario Craver a Game-Time Decision for Week 12
Sean Brady

Set For Title Eliminator Bout
Carlos Prates

A Favorite At UFC 322
Leon Edwards

Looks To Get Back In The Win Column
Benoît Saint Denis

Benoit Saint Denis Set To Open Up UFC 322 Main Card
Beneil Dariush

Looks To Win Back-To-Back Fights
CFB

Virginia's Chandler Morris Trending Toward Facing Duke on Saturday

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