X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

FanDuel MLB DFS Lineup Picks (4/21/21): Daily Fantasy Baseball Advice

Mike Marteny highlights the top FanDuel MLB DFS lineup picks for 4/21/21, and a couple of sleepers to consider while building daily rosters.

It's getaway day in MLB, so only six games permeate the main night slate. Only one pitcher tips the five-figure scale. Can we get away with a fade here? Are there enough other options to gain an advantage by using a cheaper pitcher? We'll get into that.

Rain could affect the start time of the Yankees game, but they should be able to get the game in after an initial delay. The only thing to worry about would be if they can't keep the field in good shape when it rains throughout the afternoon. I do expect it to play and the wind should be blowing heavily out to right. Use pitching at your own risk in that one. They are going to have problems getting the Boston game in. It's possible that the rain will miss Boston, but right now it doesn't look promising.

I'll be providing you with my daily fantasy baseball lineup picks for the FanDuel main slate on 4/21/2021. Be sure to also check out all the MLB player news, including late scratches, and the projected and confirmed daily MLB lineups for each DFS slate. You can also check out today's DraftKings MLB DFS lineup picks, and read more DFS advice and lineup picks for other sports too. Let's get to it!

 

FanDuel DFS Pitchers

Cash Game/GPP Anchor Play:

Aaron Civale – CWS at CLE($10,200)

Civale beat the White Sox just five days ago, but he only picked up four strikeouts. The lack of strikeout potential is a bit of a ding on him, but he is 3-0 with a 2.18 ERA so far this year. Civale hasn't gone less than six innings in any start this year. That alone gives him the highest floor on this slate. Civale isn't a high strikeout guy so I can get on board with a fade here. The big issue is that there aren't many good secondary options.

Potential Alternate Play

Tyler Mahle – CIN vs. ARI($8,800)   

The issue with Mahle over the course of his career has been his ability to get through the order a second time. He simply doesn't go deep into games. Over the course of 64 career starts, Mahle averages just a shade over five innings per start. That's not much time to accumulate points. This season has been much of the same with Mahle only pitching 14 innings across three starts. It has nothing to do with his effectiveness because in the start in which he only lasted four innings, Mahle did not give up a run. That was against tonight's opponent, Arizona. Mahle still picked up 30 FanDuel points in that game. The thing that has me leaning towards Mahle is the 22 strikeouts in 14 innings. That's something I can work with.

 

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's RealTalkRaph on DraftKings - join in on the winning!

 

FanDuel DFS Infielders

Joey Votto – 1B, CIN vs. AZ ($2,800)

It has been a rough start for Merrill Kelly again this year. A small ballpark with the wind blowing out wont help him either. Votto has only been shut out in one game this season and just got done with a series in which he destroyed Cleveland pitching. The Arizona staff and bullpen is significantly worse. Votto makes a lot of hard contact against the fastball and changeup that Kelly throws, which comprises almost 70% of his pitches to lefties. He should be able to stay hot here.

Ozzie Albies – 2B, ATL at NYY ($3,000)

Corey Kluber has really struggled this year and this is a terrible matchup for him anyway. Kluber's fastball velocity is down a bit which could explain the struggles. Still, this is not a team you want to struggle against. I'm not going hard after Kluber since the Yankees bullpen has one again been a strength. Albies profiles well and is reasonably priced.

Jose Ramirez – 3B, CLE vs. CWS ($3,300)

This feels cheap for Ramirez, especially when you consider that the White Sox basically turning this into a bullpen game. Ramirez started slowly, but he has 78.4 FanDuel points over the last five games. I'm not scared of Jonathan Stiever or the White Sox bullpen. Stiever struggled in his cup of coffee in 2020 and he didn't have a strong spring either. ATTACK!

Javier Baez – SS, CHC vs. NYM ($3,800)

Kris Bryant has been the talk of the Cubs this year and for good reason. However, he doesn't profile nearly as well as Baez does. Baez absolutely destroys sliders with a 72.7% hard contact rate. The only thing he doesn't profile well against is changeups. All eight home runs that David Peterson has allowed in his career have been given up to righties. If anyone is hitting one in Wrigley tonight, the metrics strongly suggest that it will be Baez.

 

FanDuel DFS Outfielders

Jesse Winker – OF, CIN vs. AZ ($3,700)

Winker is leading off a potent offense against a pitcher that has given up a run per inning so far this year in a small ballpark with the wind blowing out. The Arizona bullpen has been one of the better units so far this year, but I'm banking on the Reds putting up some big numbers against Kelly before they knock him out of the game.

Franmil Reyes – OF, CLE vs. CWS ($3,200)

Reyes has the rawest power of anyone on the team. Reyes made up for his cold series on the Southside last week in which he went 0-13 by picking up three hits and a walk in the first game of the series in Cleveland. We don't really know who or what the White Sox are going to throw at Cleveland tonight. We only know that Jonathan Stievers will be part of it. That's good enough for me knowing he has a bullpen with an ERA on the wrong side of 4 backing him up.

Jorge Soler – OF, KC vs. TB($2,600)

Soler is quite familiar with Michael Wacha. He started his career with the Cubs when Wacha was with the Cardinals. Then Soler moved to Kansas City where they play the Cardinals in the I-70 series every year. Wacha is 5-12 with three homers, seven runs, and seven RBI in his career against Wacha. BvP worked for those of us last night who threw a struggling Mitch Moreland out there against Matt Shoemaker. This could work for a struggling Soler as well.

 

FanDuel DFS Stacks Options

  • Cincinnati Reds
  • Kansas City Royals
  • Cleveland Indians
  • Chicago Cubs right-handers



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!




MLB DFS News and Injury Alerts


More DFS Lineup Picks and Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Chase Elliott

Was Somewhat Lucky, but Still Had Best Run at Gateway
NASCAR

Bubba Wallace Won Stage 2, but Was Let Down by Strategy
Tyler Reddick

Despite Myriad Bad Luck, Tyler Reddick Did What He Needed to Do
Chase Briscoe

Recovers from Incident with Daniel Suarez to Finish Second
William Byron

Late Caution Foils William Byron's Shot at Gateway Victory
Jaxon Smith-Njigba

Dominates Targets in Seattle, Records 124 Receiving Yards in Week 1
Puka Nacua

Leads Rams in Targets, Catches, and Receiving Yards in Week 1
Logan O'Hoppe

Exits After Concussion Scare, Status Remains Unclear
Christian McCaffrey

Logs 31 Touches in Season Opener
Travis Etienne Jr.

Dominates Backfield Touches in Jacksonville, Posts Monster Day
Jayson Tatum

"Moving Around Way Better"
Russell Wilson

Giants Won't Commit to Russell Wilson as Week 2 Starter
Drake London

Day-to-Day with Shoulder Sprain
George Kittle

and Jauan Jennings to Undergo MRIs
Jake Moody

49ers to Evaluate Kicker Position After Jake Moody Struggles
Evan Engram

Questionable to Return Against Titans
Daniel Palencia

to Miss Time With Shoulder Injury
Jauan Jennings

Questionable to Return With Shoulder Injury
Emeka Egbuka

Scores Twice in NFL Debut
Aaron Rodgers

Throws Four Touchdowns in Week 1
Justin Fields

Scores Three Times in Loss
Daniel Jones

Excellent in Colts Debut Sunday
Puka Nacua

Clears Concussion Check, Returns to Game
George Kittle

Scores TD Before Being Ruled Out With Hamstring Injury
Puka Nacua

Taken to Locker Room for Concussion Evaluation
Brock Bowers

Expected to be Fine, No Injury Concerns
Byron Buxton

Exits Early With Knee Contusion
Drake London

Injures Shoulder, Questionable to Return
Trea Turner

Suffers Hamstring Strain
Brock Bowers

Questionable to Return in Week 1
Jonathan Taylor

Exits Game With Apparent Injury
Ryan Blaney

Should Contend at Gateway
Denny Hamlin

Fastest in Qualifying, the Favorite to Win at Gateway
Christopher Bell

Looking for Redemption at Gateway
Joey Logano

Has Been Elite at Gateway
Austin Cindric

Should Be On Your Radar at Gateway
AJ Allmendinger

Could Be a Sleeper Again at Gateway
Tyler Reddick

Southern 500 Near-Miss Makes Tyler Reddick a Stronger Option for Gateway
NASCAR

Bubba Wallace a Likely Gateway Contender
Alex Bowman

a Long Shot to Advance in Playoffs
Austin Dillon

Richard Childress Racing Looks Slower at Gateway, Which Will Hurt Austin Dillon
Shane Van Gisbergen

Starts 18th in Gateway Debut
Ty Gibbs

Toyota Speed May Help Ty Gibbs at Gateway
Brad Keselowski

Probably the Best DFS Place-Differential Option
Chris Buescher

May Have Qualified Too Well to Start for DFS
Kyle Busch

If Kyle Busch Contends Anywhere, it Could be at Gateway
NASCAR

John Hunter Nemechek Could Benefit From Toyota Speed Like he Did at Darlington
Bubba Chandler

to Make First Start on Sunday
Samuel Basallo

Exits Early with Hand Injury
Jeremy Swayman

Ready to Get Back on Track
Connor McDavid

Aiming for More Goals
NJ

Luke Glendening Signs Tryout Deal With Devils
Pete Crow-Armstrong

Leaves Early on Saturday After Fouling Ball Off his Knee
Dylan Harper

Hoping to be Ready for the Opener Versus Dallas
EDM

Derek Ryan Retires From Hockey
Connor Zary

Agrees to Three-Year Deal With Flames
Carey Price

Canadiens Trade Carey Price to Sharks
Bobby Witt Jr.

Dealing With Back Spasms
Bobby Witt Jr.

Exits Early on Friday
Adolis García

Adolis Garcia Placed on Injured List With Quad Strain
Tyler Glasnow

Scratched on Friday With Back Tightness
Rasmus Hojgaard

Finishes Tied For Second at Omega European Masters
Tyrrell Hatton

Finishes Tied for 32nd at LIV Indianapolis
Matt Fitzpatrick

Finishes Fifth at Omega European Masters
Patrick Cantlay

Finishes Tied For Second in 2025 FedEx Cup Standings
Xander Schauffele

Finishes 42nd in 2025 FedEx Cup Standings
Tyler Glasnow

Scratched From Friday's Start for Undisclosed Reasons
Shohei Ohtani

Returning to the Mound on Friday
Kyle Finnegan

Lands on Injured List With Adductor Strain
Aaron Judge

Returns to Right Field on Friday
Willson Contreras

' Suspension Reduced, to Start Serving it on Friday
Kodai Senga

Mets Send Kodai Senga to Triple-A to Get Right
Caio Borralho

Set For A Title Eliminator Bout
Nassourdine Imavov

Looks To Earn A Title Shot
Mauricio Ruffy

Looks To Extend His Win Streak
Benoît Saint Denis

Benoit Saint Denis Set For UFC Paris Co-Main Event
Modestas Bukauskas

Looks To Extend His Win Streak
Paul Craig

In Dire Need Of Victory
Mason Jones

Set for Main-Card Bout
Bolaji Oki

Looks To Win Back-To-Back Fights
Rhys McKee

Set To Open Up UFC Paris Main Card
Axel Sola

Alex Sola Set To Make His UFC Debut
Pablo López

Pablo Lopez Expected to Return on Friday
Jazz Chisholm Jr.

Exits With Knee Contusions
Will Smith

Unlikely to Play This Weekend
Shohei Ohtani

to Pitch on Monday
Jon Rahm

Looks to Prove His Importance on European Ryder Cup Team
Tommy Fleetwood

Among Leaders of European Ryder Cup Team
Alperen Sengün

Alperen Sengun Close to Triple-Double Versus Serbia
Nikola Jokić

Nikola Jokic Fills Box Score Against Turkey
Nikola Jović

Nikola Jovic Shakes Off Minor Injury
E.J. Liddell

Inks Two-Way Deal With Nets
NBA

Ben Simmons Reportedly Considering Retirement
P.J. Washington

Agrees to Four-Year, $90 Million Extension
Sepp Straka

Gets Captain's Pick to Join Team Europe
PGA

Victor Hovland to Make Third Ryder Cup Appearance for Team Europe
J.J. Spaun

Set to Represent Team USA for First Time at Bethpage
Russell Henley

Makes First Ryder Cup Appearance at Bethpage
Harris English

Named to Ryder Cup Team for Second Time
Justin Thomas

Making Fourth Ryder Cup Team Appearance at Bethpage
Ben Griffin

Making First Career Ryder Cup Appearance at Bethpage
Bryson DeChambeau

Set to be Part of Team USA at Bethpage
Santi Aldama

Bags Double-Double in Losing Effort
Guerschon Yabusele

Erupts for 36 Points Against Poland
Luka Dončić

Luka Doncic Leads Slovenia Into Next Round at EuroBasket
San Antonio Spurs

Stanley Umude Signs Training Camp Deal With Spurs
Reece Beekman

Joins Magic for Training Camp
Justin Minaya

Signs Exhibit 10 Deal With Magic
Alexandre Sarr

to Miss Rest of EuroBasket
Jared McCain

"On Pace" for Training Camp
Luke Hughes

Devils Optimistic About Signing Luke Hughes
Martin Fehérváry

Martin Fehervary on Track to Be Ready for Training Camp
Dylan Holloway

Good to Go for Start of Season
Josh Morrissey

Fully Healthy for Start of Season
Dennis Hildeby

Signs Three-Year Extension With Maple Leafs
Franz Wagner

Collects Double-Double in Blowout Win
Alperen Sengün

Alperen Sengun Achieves Rare Numbers at EuroBasket
Nikola Vučević

Nikola Vucevic Dominates Against Sweden
Kristaps Porzingis

Finding Form at EuroBasket
Nikola Jović

Nikola Jovic Suffers Minor Injury at EuroBasket

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP