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The Indianapolis Colts defense has been a stout fantasy unit through the first six games of the regular season. They will be tested on the road in a Week 7 matchup against the Los Angeles Chargers. The Chargers are dealing with plenty of injuries on offense, but they are still allowing just the 14th-most fantasy points per game to opposing D/STs in fantasy. The Colts are set as 1.5-point road underdogs in a game with a high 48.5-point over/under. This is a difficult spot for the Colts, which puts them outside of the top-12 fantasy defenses for this weekend.--Matt Terelle
Source: NFL.com
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REAL-TIME FANTASY NEWS

Jeff Skinner

Remains Sidelined Wednesday
Petr Mrazek

Out 2-3 Weeks
Pelle Larsson

Set to Suit Up Versus Dallas
Tyler Seguin

Likely Done for the Season
P.J. Washington

Ruled Out Against Miami
Neal Pionk

Returns to Jets Lineup
Jalen Smith

to Miss Third Straight Game
Duncan Robinson

Sidelined Again Wednesday
J.J. McCarthy

Practices in Full, on Track to Return in Week 14
Daniel Gafford

Set To Play Against Heat
Tre Jones

Ruled Out for Wednesday's Game
LaMelo Ball

Good to Go on Wednesday
Steven Adams

Cleared To Play Against Kings
Deni Avdija

is Available to Play on Wednesday
Kevin Porter Jr.

Available on Wednesday
Bobby Portis

Available to Play on Wednesday
Lonzo Ball

Upgraded To Available Against Portland
Giannis Antetokounmpo

Cleared for Wednesday's Game
Jamal Murray

Cleared To Play Against Indiana
Nikola Jokić

Nikola Jokic Available on Wednesday Night
Luka Dončić

Luka Doncic Ruled Out on Thursday Due to a Personal Matter
Norman Powell

Sidelined Versus Mavericks
Mark Andrews

Agrees to Three-Year Extension With Ravens
Devin Booker

Out at Least One Week
Freddy Peralta

Brewers Considering Trading Freddy Peralta
Kyle Schwarber

Reds Serious About Adding Kyle Schwarber in Free Agency?
Amon-Ra St. Brown

Officially Questionable for Thursday Night
Omarion Hampton

"on Track and Looking Good" for Week 14
CFB

Brent Key Signing Five-Year Deal to Remain at Georgia Tech
Joey Bosa

Week-to-Week With Hamstring Injury
Bryce Young

Panthers Expected to Pick Up Bryce Young's Fifth-Year Option
Deshaun Watson

Browns Opening Practice Window for Deshaun Watson
CFB

Brian Hartline Expected to Land USF Head-Coaching Job
CFB

Collin Klein Expected to be Top Target for Kansas State if Head-Coach Job Opens
CFB

Chris Klieman Considering Stepping Down at Kansas State
Aaron Rodgers

Appears to be Healthier Heading into Week 14
Jalen McMillan

Expected to Have his 21-day Practice Window Opened
Mike Evans

' Practice Window Opened, Returning to Practice on Wednesday
Dennis Schröder

Dennis Schroder Carrying Questionable Tag vs. Houston
Steven Adams

Questionable To Face Kings
Tre Jones

Expected To Suit Up Against Nets
Alexander Wennberg

a Game-Time Call Wednesday
Michael Callahan

Sustains Lower-Body Injury Tuesday
Michael Rasmussen

Makes Early Exit Tuesday
Scott Wedgewood

Exits Early With Back Problem
Evander Kane

Expected to Be Fine After Skate Cut
Tyler Seguin

Injured Versus Rangers
Sean Monahan

Expected to Play Thursday
Nathan Walker

Out for Eight Weeks
Lian Bichsel

to Sit Out 6-8 Weeks
Viktor Arvidsson

Activated From Injured Reserve
Warren Foegele

Remains Out Tuesday
Valeri Nichushkin

Available After Eight-Game Absence
Gabriel Landeskog

Nathan MacKinnon, Gabriel Landeskog Cleared for Tuesday
Tyson Foerster

to Miss 2-3 Months
CFB

D.J. Durkin Staying at Auburn Under Alex Golesh
CFB

Charlie Weis Jr. Permitted to Coach Ole Miss Offense in College Football Playoff
Tyrone Tracy Jr.

Says he's Fine After Suffering Hip Contusion
Omarion Hampton

Likely to Return in Week 14
CFB

Five-Star Quarterback Jared Curtis Flips Commitment From Georgia to Vanderbilt
CFB

Florida Hiring Brad White as Defensive Coordinator
Kyle Schwarber

Giants Have Checked in on Kyle Schwarber
Willson Contreras

Willing to Waive his Full No-Trade Clause?
Brandon Aiyuk

49ers "Hopeful" Brandon Aiyuk Will Play in 2025
Brayden Point

Without Timetable for Return
Jake Walman

Still Out Tuesday
Mason Appleton

Misses Tuesday's Contest
Tyrone Tracy Jr.

Carted Off With Hip Injury on Monday Night
Edwin Díaz

Mets Still Interested in Re-Signing Edwin Diaz
Devin Williams

Agrees to Three-Year Deal With Mets
Cole Ragans

Red Sox Targeting Cole Ragans in a Trade?
CFB

Kentucky Hires Oregon Offensive Coordinator Will Stein As Head Coach
Davante Adams

Not Dealing With a Serious Injury
Kyler Murray

Surgery Not on the Table for Kyler Murray
Marvin Harrison Jr.

in Danger of Missing Week 14?
CFB

Kalani Sitake the Top Target for Penn State Coaching Job
Justin Herbert

Having Hand Surgery on Monday
Kyler Murray

Cardinals Won't Open Kyler Murray's Practice Window This Week
Sauce Gardner

Not a Candidate to Go on Injured Reserve
Jayden Daniels

Not Cleared for Contact, Decision on Week 14 Status Delayed
CFB

Josh Heupel Says He's Not a Candidate for Penn State Head Coach Job
CFB

Will Stein, Brian Hartline the Top Candidates for Kentucky Job?
CFB

Nebraska Fires Defensive Coordinator John Butler After One Season
CFB

UCLA Expected to Hire Bob Chesney as Next Head Coach
CFB

Lane Kiffin to Make $13 Million Salary, Ties Kirby Smart
CFB

Buster Faulkner, Joey Halzle Candidates for Florida Offensive Coordinator Job?
CFB

Kentucky Officially Fires Mark Stoops
CFB

Lane Kiffin to be Introduced as LSU's Next Head Coach on Monday
CFB

Florida Poised to Land Jon Sumrall as Next Head Coach
CFB

Alex Golesh Taking Over Auburn Head-Coaching Job
CFB

Arkansas Expected to Hire Ryan Silverfield as Next Head Coach
Zack Wheeler

Likely to Return in May
Ryan Helsley

Agrees to Two-Year Deal With Orioles
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