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The Indianapolis Colts defense has been a stout fantasy unit through the first six games of the regular season. They will be tested on the road in a Week 7 matchup against the Los Angeles Chargers. The Chargers are dealing with plenty of injuries on offense, but they are still allowing just the 14th-most fantasy points per game to opposing D/STs in fantasy. The Colts are set as 1.5-point road underdogs in a game with a high 48.5-point over/under. This is a difficult spot for the Colts, which puts them outside of the top-12 fantasy defenses for this weekend.--Matt Terelle
Source: NFL.com
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REAL-TIME FANTASY NEWS

Deebo Samuel Sr.

Questionable for Week 7
Kyler Murray

Officially Questionable for Week 7
George Kittle

Likely Playing in Week 7
Alexander Romanov

to Be a Game-Time Call Saturday
Nils Lundkvist

Nursing Lower-Body Injury
Justin Danforth

Expected to Miss More Than One Month
Brock Bowers

Considered Doubtful for Week 7
Jonathan Huberdeau

Set for Season Debut Saturday
Brock Purdy

Ruled Out Again in Week 7
Liam O'Brien

Makes Season Debut Friday
Marvin Harrison Jr.

Clears Concussion Protocol, Will be Active on Sunday
Pierre-Luc Dubois

Out Against Wild
Lucas Raymond

to Remain Out Friday
CeeDee Lamb

Off the Injury Report, Will Return in Week 7
Anze Kopitar

Out Week-to-Week
Josh Jacobs

Listed as Questionable For Week 7
Iván Herrera

Ivan Herrera Has Bone Spurs Removed From his Elbow
Carson Wentz

Named Vikings' Starting Quarterback in Week 7
Brendan Allen

Set For UFC Vancouver Main Event
Reinier de Ridder

Reinier De Ridder A Favorite At UFC Vancouver
Mike Malott

Looks For His Third Consecutive Win
Puka Nacua

Rams "Very Optimistic" Puka Nacua Will Return After Week 8 Bye
Kevin Holland

Set For UFC Vancouver Co-Main Event
Aiemann Zahabi

Looks For His Seventh Consecutive Win
D'Andre Swift

Bears "Hopeful" That D'Andre Swift Will Play in Week 7
Bradley Beal

Set to Make Clippers Debut in Preseason Finale
Marlon Vera

Returns At UFC Vancouver
VJ Edgecombe

Set to Return for Preseason Finale
Calvin Ridley

Ruled Out for Sunday
Jeremy Sochan

Won't Play in Season Opener
Jasmine Jasudavicius

Looks To Extend Her Win Streak
AJ Green

Bucks Agree to Contract Extension
Manon Fiorot

Looks To Bounce Back
Stefon Diggs

Questionable for Sunday
Aoriqileng

Aori Aoriqileng Looks To Rebound
Cody Gibson

Looks To Get Back In The Win Column
Jaylen Brown

Considered Day-to-Day with Hamstring Tightness
Kyle Nelson

Set For Lightweight Bout
Matt Frevola

Set To Open Up UFC Vancouver Main Card
Jaden Ivey

Will Miss Four Weeks After Knee Surgery
Paul George

Expected to Miss Season Opener
Chuba Hubbard

Will Return in Week 7
Joel Embiid

Set to Make Preseason Debut on Friday
Terry McLaurin

Ruled Out for Week 7
Puka Nacua

Inactive for Week 7
Garrett Wilson

Will Not Play in Week 7, Could Return in Week 8?
Chase Brown

Goes for Over 100 Rushing Yards in Win Over Steelers
Mark Stone

Stays Hot With Hat Trick of Assists
Evgeni Malkin

Continues Prolific Start
Shane Pinto

Pots Sixth Goal of the Campaign
Cole Caufield

Pushes Canadiens Past Predators
Shayne Gostisbehere

Delivers Three Assists in Thursday's Win
Matthew Schaefer

Makes History With Another Assist
Bo Horvat

Nets Second Career Hat Trick
Frederick Gaudreau

Sustains Undisclosed Injury Thursday
Jaylen Warren

Highly Efficient on the Ground Thursday, Adds Value as Receiver
Aaron Rodgers

Fails to Finish Comeback Despite Throwing for Four Touchdowns
Joe Flacco

Flashes Vintage Form in Comeback Win Thursday
CFB

Curt Cignetti Signs Eight-Year, $11.6 Million Extension With Indiana
Carlos Rodón

Carlos Rodon Unlikely to Be Ready for Opening Day After Elbow Surgery
Anthony Santander

Removed From ALCS Roster With Back Injury
Jackson Chourio

Aggravates Hamstring, Pulled Early in Game 3 of NLCS
Brady Tkachuk

to Miss 6-8 Weeks After Having Thumb Surgery
Noah Hanifin

Remains Sidelined Thursday
Akira Schmid

Faces Bruins Thursday
Jake Allen

Starts Against Panthers
Troy Terry

Expected to Play Thursday
Aaron Judge

Will Not Need Elbow Surgery
Anthony Volpe

Won't be Ready for Start of Next Season
Gerrit Cole

Won't be Ready for Opening Day Next Year
Milwaukee Bucks

Chris Livingston Waived by the Bucks
Keegan Murray

Nique Clifford Shines in Keegan Murray's Absence
Cooper Flagg

Continues to Start at Point Guard
Ron Harper Jr.

Earns a Two-Way Deal with the Celtics
Charlotte Hornets

Spencer Dinwiddie Waived by the Hornets
Tampa Bay Buccaneers

Sterling Shepard's Stock Rising for Buccaneers
CFB

Jermod McCoy Officially Out for Alabama Matchup
CFB

Jam Miller Questionable to Face Tennessee
Jaden Ivey

Considered Day-to-Day
Josh Hart

Making Progress
Jaren Jackson Jr.

Busy in Preseason Debut
Keegan Murray

Lands Five-Year, $140 Million Extension
Domantas Sabonis

Sustains Hamstring Injury Wednesday
Jaylen Brown

"Fine" Following Wednesday's Early Exit
CFB

Arizona State QB Sam Leavitt Probable For Saturday
Kevon Looney

Slated to be Sidelined With Knee Injury
Anthony Volpe

Undergoes Left-Shoulder Surgery
CFB

Jayden Gibson No Longer with Oklahoma Program
Emmanuel Clase

to be Banished for Life After Gambling Allegations?
Alex Bregman

Plans to Opt Out of Contract With Red Sox
Christopher Bell

Sits Third in Points After Quiet Third-Place Finish
Chase Briscoe

Passes Denny Hamlin at the Start, but Hamlin Gets Him in the End
Joey Logano

Falling Out of Playoff Picture Despite Other Contenders' Crashes
Ryan Blaney

Stage 1 Crash Puts Ryan Blaney in Severe Playoff Trouble
Denny Hamlin

Wins at Las Vegas and Will Compete for the 2025 Cup Series Title
Kyle Larson

Dominates at Las Vegas but Ends Up Second
Chase Elliott

Struggles to Gain A Solid Finish at Las Vegas After Pit-Road Penalty
William Byron

Strong Run Ends In A Wreck at Las Vegas
CFB

Sam Leavitt Viewed as Day-to-Day with Undisclosed Injury
Anthony Santander

Scratched From Game 2 of ALCS With Back Tightness
San Diego Padres

Mike Shildt Retires as a Manager
Mateusz Gamrot

Suffers Second-Round Submission Loss
Charles Oliveira

Gets Back In The Win Column
Montel Jackson

Drops Decision
Deiveson Figueiredo

Gets Split-Decision Victory
Vicente Luque

Outclassed
Vicente Luque

Joel Alvarez Outclasses Vicente Luque
Jhonata Diniz

Suffers Second-Round TKO Loss
Mario Pinto

Remains Undefeated
CFB

Matt Rhule Denying Interest in Penn State Head Coaching Job
CFB

Le'Veon Moss Not Believed to Have Suffered Season-Ending Injury
Ricardo Ramos

Suffers First-Round Submission Loss
CFB

Bill Belichick Says he's Committed to North Carolina
Tiger Woods

Undergoes Back Surgery
CFB

UAB Fires Head Coach Trent Dilfer After 2.5 Seasons In Birmingham
CFB

Penn State Fires Head Coach James Franklin After 10.5 Seasons
CFB

Penn State QB Drew Allar Will Miss The Rest Of 2025 Season With Ankle Injury
Brandon Woodruff

Will Not be on NLCS Roster
Max Scherzer

Added to ALCS Roster
Bryan Woo

Makes ALCS Roster
Bo Bichette

Won't Make ALCS Roster
Christopher Bell

the Favorite to Win at Las Vegas
Denny Hamlin

on the Pole at Las Vegas
Joey Logano

Can Joey Logano Get Lucky in Las Vegas Again?
William Byron

has the Fastest Car in Practice at Las Vegas
Ty Gibbs

Speed of Ty Gibbs a Good Sign for Toyota at Las Vegas
NASCAR

Bubba Wallace Should Contend at Las Vegas
Ross Chastain

Scrapes Wall in Practice But Qualifies 15th at Las Vegas
Chris Buescher

Looking for Improvement at Las Vegas
Austin Cindric

It Has Been Hit or Miss for Austin Cindric at Las Vegas
Chase Elliott

Should Run Well at Las Vegas
Kyle Larson

Conservatism May Keep him from Replicating Previous Las Vegas Drive
Josh Berry

After Josh Berry's Las Vegas Win, Ryan Blaney Should be a Top Contender
Chase Briscoe

has Definitely Improved on Intermediate Tracks
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