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NBA DFS: Top Daily Fantasy Expert Picks for DraftKings, FanDuel (4/21/25)

Jalen Brunson - NBA DFS Lineup Picks, Daily Fantasy Basketball

CeeGee's favorite NBA DFS picks for today, Monday 4/21/25. His top daily fantasy basketball lineup sleepers and value picks for Draftkings and FanDuel DFS contests.

Welcome back, RotoBallers, I hope you had a wonderful Easter weekend! We’ve got a compact two-game slate tonight featuring Game 2 matchups in the first round of the NBA Playoffs. The New York Knicks host the Detroit Pistons, looking to take a 2-0 lead after a strong Game 1 win, while the Denver Nuggets face the Los Angeles Clippers in a tighter contest where the Clippers are slight favorites on the road.

With only four teams in play, roster construction will be tricky. Balancing the studs, such as Nikola Jokic and Karl-Anthony Towns, with the right value plays will be key.

This article will provide my daily fantasy basketball lineup picks for FanDuel on 4/21/25. Remember to monitor NBA injury news and our awesome NBA injuries report tool, as the slate can completely change before lineups lock at 7:30 p.m. EST on FanDuel. 

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NBA DFS Core Picks

These are your lineup cornerstones, players with safe floors and matchup-driven upside for both cash and GPP formats.

Nikola Jokic - DEN - C ($11.5K DK, $12.5K FD)

Jokic is the slate’s must-have stud. Fresh off a near triple-double in Game 1 (29 points, nine rebounds, 12 assists), Jokic showed why he’s a DFS cheat code. The Clippers are no slouches defensively, boasting a third-ranked defensive rating and fourth-ranked points allowed per game, but Jokic’s unique skill set makes him just impossible to cover. His 29 percent usage rate and insane 1.84 DK points per minute give him a rock-solid 50+ fantasy point floor, with 70+ upside if this game stays close like Game 1.

Ivica Zubac is a strong defender and held his own, but Jokic’s ability to score in the post, pop out for threes, and facilitate for teammates like Aaron Gordon keeps him a step ahead. The Clippers’ fourth-ranked rebounding rate is stout, but Jokic can still exploit their 10th-ranked 3-point attempts allowed with his outside touch. He’s your anchor for cash games and a GPP monster with that ceiling.

Karl-Anthony Towns - NYK - C ($9.3K DK, $10.1K FD)

If you’re looking to save some salary or pivot off Jokic, Towns is an absolute gem. KAT was a force in Game 1, dropping 23 points and grabbing 11 rebounds while shooting an absurd 71.4 percent from the field. Detroit’s frontcourt, led by Jalen Duren, is solid on the boards (fifth in rebounding rate), but their 14th-ranked points allowed leaves the door open for Towns to dominate. Rocking a 27 percent usage rate and 1.41 DK points per minute, he’s got a safe 40+ fantasy point floor with 50+ upside if he gets hot.

The real kicker? Detroit’s 25th-ranked 3-point percentage allowed means Towns can stretch the floor and bury open looks from deep while still doing damage inside. He’s a fantastic cash game play with the consistency to shine in GPPs, especially in a game with a juicy 114.3 implied total for the Knicks.

Jalen Brunson - NYK - PG ($8.3K DK, $8.8K FD)

Jalen Brunson is your guy if you want a guard who can take over a game. In Game 1, he shook off a slow start and a tweaked ankle to drop 34 points and lead the Knicks’ epic comeback. With a 29 percent usage rate that climbs to 33 percent in crunch time, Brunson is a steal at sub-$9K on both sites, offering a 40+ fantasy point floor and 50+ ceiling. Detroit’s defense isn’t elite (14th in points allowed, 10th in defensive rating), and Cade Cunningham isn’t exactly locking down the perimeter, which sets Brunson up to feast.

The Pistons’ 12th-ranked 3-point attempts allowed could let him catch fire from deep, and with the Knicks’ 114.3 implied total signaling a high-scoring game, Brunson’s scoring and assist potential make him a cash game lock. If he goes full takeover mode again, you’re looking at GPP-winning production.

 

NBA DFS Tournament Pivots

These players offer high ceilings at potentially lower ownership, perfect for GPPs where differentiation is key.

Cade Cunningham - DET - PG ($9.1K DK, $10.3K FD)

If you’re hunting for a GPP game-changer, Cade Cunningham is worth a long look. He had a solid but frustrating Game 1, putting up 21 points and 12 assists but struggling with his shot (8-for-21). That inefficiency might scare some folks off, which is precisely why he’s a sneaky tournament play. With a 32 percent usage rate and 1.45 DK points per minute, Cunningham’s got the kind of ceiling that can match the slate’s top dogs, especially with Detroit’s 107.8 implied total suggesting they’ll hang around.

The Knicks’ ninth-ranked points allowed and 26th-ranked pace could turn this into a slower-paced game, but if Cade is more efficient than Game 1, he could rack up plenty of points and assists. Brunson is not an elite defender, and New York’s eighth-ranked rebounding rate gives Cunningham a chance to sneak in some boards for extra fantasy juice. If his shot starts falling, we’re talking 50+ fantasy points, making him a high-upside pivot at potentially lower ownership.

Aaron Gordon - DEN - PF/C (DraftKings Only) ($5.9K DK, $6K FD)

Want a budget-friendly GPP dart throw? Aaron Gordon’s your guy. He went off in Game 1, dropping 25 points and eight rebounds by attacking the rim and capitalizing on Denver’s need for secondary scoring. At just $5.9K on DK, his 19 percent usage rate (which spikes when Jokic or Murray aren’t cooking) and 30+ fantasy point ceiling make him a steal. The Clippers’ elite defense (third in defensive rating, fourth in points allowed) is no joke, but their 21st-ranked 3-point attempts allowed and 22nd-ranked pace keep this game fast enough for Gordon to shine on cuts and in transition.

Kawhi Leonard’s a tough matchup, but Gordon’s athleticism and ability to crash the glass against L.A.’s fourth-ranked rebounding rate give him sneaky upside. With most DFS players locking in Jokic or Jamal Murray, Gordon’s lower ownership makes him a perfect differentiator for those big tournament payouts.

OG Anunoby - NYK - SF/PF ($6.8K DK, $7.3K FD)

OG Anunoby is the kind of under-the-radar play that can win you a GPP. In Game 1, he quietly dropped 23 points and seven rebounds, stepping up with a 20 percent usage rate that shows he’s more than just a defensive stud. Detroit’s 14th-ranked points allowed and 12th-ranked 3-point attempts allowed set up nicely for Anunoby’s two-way game, and with the Knicks’ 114.3 implied total, he’s got a shot at 35-40 fantasy points if his shot is on.

Ausar Thompson’s a pesky defender, but Anunoby’s size and shooting give him the edge, especially since Detroit ranks 25th in 3-point percentage allowed, leaving the door open for some open looks from deep. While Brunson and Towns soak up most of the ownership, Anunoby’s ability to contribute across the stat sheet—points, rebounds, steals, and blocks—makes him a sneaky pivot for those looking to zig when others zag.

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NBA DFS Value Picks

These sub-$6,000 players provide salary relief while offering strong upside, often due to minutes or matchup boosts.

Malik Beasley - DET - SG/SF ($5.3K DK, $5.6K FD)

If you’re looking to save some salary without sacrificing upside, Malik Beasley is a fantastic option. He came off the bench in Game 1 and torched the Knicks, dropping 20 points, including 6-for-12 from three, in nearly 35 minutes. With a 22 percent usage rate and 0.91 DK points per minute, Beasley’s a steal at this price, especially with Detroit needing his shooting to keep up with New York’s 114.3 implied total.

The Knicks rank fifth in 3-point attempts allowed and a porous 26th in 3-point percentage allowed, which is like rolling out the red carpet for Beasley’s long-range game. His role as Detroit’s go-to bench scorer locks in his minutes, and if he stays hot from deep, we’re looking at 25-30 fantasy points at low ownership, making him a dream GPP play where his three-point reliance could pay off big.

Cameron Payne - NYK - PG/SG ($3.4K DK, $4.2K FD)

Talk about a bargain, Cameron Payne is way too cheap for the spark he brings. In Game 1, he was a straight-up microwave off the bench, dropping 14 points, including 3-for-5 from three, in just 14.7 minutes. With a 20 percent usage rate and an elite 0.98 DK points per minute, Payne’s $3,400 DK price is practically begging to be rostered.

The Knicks’ bench desperately needs his scoring punch, and Detroit’s 14th-ranked points allowed give him a great shot to keep the hot hand. If this game stays close, Payne could easily see 15-20 minutes again, which would put him in the 20+ fantasy point range with room for more if he catches fire. His dirt-cheap price makes him a no-brainer for both cash games and GPPs, offering a solid floor and a ceiling that could swing a tournament.

Isaiah Stewart - DET - C/PF (FanDuel Only) ($3.7K DK, $4.7K FD)

For those deep value hunters, Isaiah Stewart is a punt play with some potential. In Game 1, he played 18.9 minutes off the bench, grabbing five rebounds and scoring two points, but his season average of 0.94 DK points per minute shows he can do damage when he’s on the court. At just $3,700 on DK, Stewart’s a low-cost roll of the dice, especially if Duren gets into foul trouble or Detroit needs more physicality against New York’s frontcourt.

The Knicks’ eighth-ranked rebounding rate makes it tough, but their ninth-ranked points allowed opens the door for Stewart to pile up hustle stats like rebounds and blocks. If he creeps up to 20+ minutes, he’s got a shot at 20+ fantasy points, which is massive for this price. His minutes are shaky, so he’s a GPP-only play, but the per-minute production makes him worth a look for those chasing upside.

 

My Favorite NBA DFS Picks for Today

Here is where I leave you with some of my favorites.

  • Top Overall Play: Nikola Jokic - DEN - C ($11.5K DK, $12.5K FD)
  • Best Value: Cameron Payne - NYK - PG/SG ($3.4K DK, $4.2K FD)
  • Best Cash Play: Jalen Brunson - NYK - PG ($8.3K DK, $8.8K FD)
  • Top GPP Target: Cade Cunningham - DET - PG ($9.1K DK, $10.3K FD)


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