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Oct 2, 2026, 4:13 PM ET

Houston Texans wide receiver Nico Collins (hamstring) is off the injury report and will play in his team's Week 4 matchup against the Dallas Cowboys, per DJ Bien-Aime of ESPN. Collins has missed Houston's last two games with a hamstring injury, but he practiced in full on Friday and is set to return against Dallas. The 27-year-old played well in Week 1 against the Buffalo Bills, recording seven catches for 75 yards and a touchdown on 10 targets. Collins was also very productive when healthy in 2025, hauling in 71 receptions for 1,117 yards and six touchdowns on 120 targets across 15 games. Now that he's active, Collins profiles as the clear number one option in the Houston passing game and should be considered a must-start wide receiver for fantasy managers in a favorable matchup against Dallas.--Will Brady
Source: ESPN - DJ Bien-Aime
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Oct 2, 2026, 4:12 PM ET

Los Angeles Chargers wide receiver Ladd McConkey (foot) was back on the practice field Friday after sitting out Thursday, but he wasn't doing much during the portion open to reporters. Kris Rhim of ESPN noted that McConkey did not run routes or catch passes with the other Chargers receivers and instead stood off to the side watching. His presence is still a step forward after Thursday's absence, though it doesn't tell us much yet about whether he'll be ready for Sunday's game against Seattle. McConkey was limited Wednesday before being downgraded to a non-participant Thursday. He has caught 12 of 15 targets for 183 yards and one touchdown through three games, including four receptions for 66 yards last week against Buffalo. RotoBaller currently has him at WR32 for Week 4. His official Friday participation level and final game designation will carry much more weight than simply being back on the field.--Bruno Mulé
Source: Kris Rhim
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Oct 2, 2026, 4:10 PM ET

Cincinnati Bengals wide receiver Ja'Marr Chase is coming off a strong performance in last week's loss to the Pittsburgh Steelers. Chase caught nine passes for 98 yards and a touchdown in Week 3. The superstar receiver will look to continue his strong play at home against the Jacksonville Jaguars this weekend. Chase was the only pass catcher on the team to earn double-digit targets in last week's game with 57 total points scored and the game script may be more of the same this week. This matchup with the Jaguars is tied for the week's highest over/under, set at 51.5 points as of Friday. The Jaguars defense has been one of the strongest units to begin the season, but Chase is one of the best players in the league regardless of position so he will likely find a way to succeed. Chase is ranked WR2 in our RotoBaller Week 4 PPR rankings, making him a must-start player regardless of league size or format. Fantasy managers should never take Chase out of their starting lineups until he's listed out or he's on bye--Joshua Costello
Source: ESPN.com
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Oct 2, 2026, 4:09 PM ET

New England Patriots quarterback Drake Maye (right shoulder) will not carry an injury designation into Sunday's game against the Buffalo Bills. Maye stayed on the injury report all week, but he was a full participant in every practice and said Wednesday that the shoulder hasn't bothered him. That should put the availability question to rest. His fantasy outlook is less comfortable. Maye has thrown for 585 yards, one touchdown and six interceptions through three games, including two picks in last week's loss to Jacksonville. He has helped himself on the ground with 82 rushing yards on 15 attempts, but the passing mistakes have made him difficult to trust in one-quarterback leagues. RotoBaller has Maye at QB18 for Week 4. The shoulder shouldn't be the reason fantasy managers sit him against Buffalo, but his rough start still leaves him better suited for Superflex formats or as a QB2.--Bruno Mulé
Source: Phil Perry
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Oct 2, 2026, 4:08 PM ET

Los Angeles Rams defensive end Aaron Donald (back) has been ruled out for Sunday's game against the Philadelphia Eagles. Donald didn't practice Wednesday or Thursday after Sean McVay said he was dealing with a sore back, and Nate Atkins reported Friday that the 35-year-old will not play. Donald came out of retirement this season and made his debut in Week 2 after sitting out the opener. He has four tackles and one tackle for loss in two games, without a sack. The Rams are already without Myles Garrett, who is on injured reserve following knee surgery, so their front will be missing two of its biggest names in Philadelphia. Donald's absence gives the Eagles one less interior problem to account for, which is a small boost for Jalen Hurts, Saquon Barkley and the rest of the offense.--Bruno Mulé
Source: Nate Atkins
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Oct 2, 2026, 4:06 PM ET

Cincinnati Bengals quarterback Joe Burrow will take on the Jacksonville Jaguars on Sunday in Week 4. Burrow completed 28 of his 37 pass attempts (76%) for 286 yards and three touchdowns in the 27-30 loss to the Pittsburgh Steelers. Despite putting up his best fantasy performance of the season, Burrow and the Bengals walked away with their first loss of the year last week. Cincinnati may have a difficult time getting back in the win column this week at home against the Jaguars. The Jacksonville defense has held opposing offenses to 10 points or fewer in two of their three games this season while racking up eight sacks and four interceptions. The Jaguars offense has also been potent to start the year, scoring about 27 points per game through three games. Burrow and the high-powered Bengals offense will have their hands full in this matchup, but should still be able to put up points in what could turn into a high-scoring game. This game is tied for the week's highest over/under, set at 51.5 points as of Friday. Even with a difficult matchup, Burrow is ranked QB5 in our RotoBaller Week 4 rankings. Fantasy managers should be excited for the potential of this game turning into a back-and-forth affair.--Joshua Costello
Source: ESPN.com
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Oct 2, 2026, 4:05 PM ET

Arizona Cardinals running back James Conner (foot) is progressing, but the team still isn't putting a date on his return. Head coach Mike LaFleur said Conner is doing well and reiterated that Arizona wants him back when he can perform at his normal level, not simply when he's able to get through a practice. Conner opened the season on injured reserve while continuing his recovery from the right foot injury that ended his 2025 season in Week 3. He can become eligible to practice next week after serving the required four-game absence, though the Cardinals have not said they will immediately open his 21-day window. That matters with Jeremiyah Love emerging as Arizona's lead back and Tyler Allgeier still involved. Conner is coming off back-to-back 1,000-yard rushing seasons in 2023 and 2024, but fantasy managers should treat him as a deeper-league IR stash until there is a clearer return date and role.--Bruno Mulé
Source: Tyler Drake
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Oct 2, 2026, 3:38 PM ET

Chicago Bears running back D'Andre Swift (knee) is off the final injury report after a brief scare Thursday. Swift was added to the report with the knee issue and did not practice, but Courtney Cronin of ESPN reported that he returned as a full participant Friday and has no game designation for Sunday's matchup with the New York Jets. Swift is coming off 20 carries for 84 yards in Monday night's win over Philadelphia, and he also caught two passes for four yards. He has 253 rushing yards and three touchdowns through three games. Kyle Monangai has stayed involved behind him, but Swift has led Chicago in carries every week so far. RotoBaller ranks him as RB15 for Week 4. Friday's full practice puts Swift back on track to handle his usual role Sunday.--Bruno Mulé
Source: Courtney Cronin
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Oct 2, 2026, 3:36 PM ET

Tampa Bay Buccaneers running back Kenny Gainwell hasn't experienced much success in his new offense. Through three games, Gainwell has carried the ball 10 times for 21 yards, while hauling in six receptions for 22 yards through the air. Bucs' offensive coordinator Zac Robinson has stated that they want to get Gainwell more involved. It remains to be seen how Gainwell will perform with backup quarterback Jalon Daniels under center. Gainwell could factor more into the gameplan with Daniels under center and the team likely doing more short routes and screens. The 27-year-old should be viewed as a low-end flex option for the upcoming Week 4 matchup against the Green Bay Packers.--Andy Webb
Source: Pro Football Reference
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Oct 2, 2026, 3:28 PM ET

The Kansas City Chiefs defense will face the Las Vegas Raiders in Week 4. The Chiefs defense helmed by Steve Spagnuolo has been mostly strong, outside of the 30 points given up to the Indianapolis Colts in Week 2. The Kansas City unit has come away with one interception in every game this season and will look to extend that streak against Raiders quarterback Kirk Cousins. The Raiders have put up at least 26 points in every game this season, making this a difficult matchup for the Chiefs. L'Jarius Sneed was listed on the injury report with a knee injury this week, but logged limited practices before a full practice on Friday. With the removal of Sneed from the injury report, the entire Chiefs defense should be at full strength to take on a division rival. The Chiefs defense is ranked ninth in our RotoBaller Week 4 rankings, making it a top-10 option at the position this week.--Joshua Costello
Source: Chiefs.com
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Oct 2, 2026, 3:26 PM ET

Buffalo Bills wide receiver DJ Moore (shoulder) is off the injury report and will not carry a game designation into Sunday's matchup with New England. Moore was limited Wednesday and Thursday in a non-contact jersey, so this is a meaningful step after another week of managing the shoulder. The injury knocked him out late in the second quarter against Detroit in Week 2, but it didn't keep his role down when he returned against the Chargers. Moore saw 10 targets in that game, catching six for 67 yards. He has 11 receptions for 167 yards and a touchdown through three games, with Week 2 cutting one outing short. RotoBaller lists him at WR22 for Week 4. There is still some risk that the shoulder gets aggravated again, but Buffalo's final designation gives fantasy managers no reason to expect him to sit Sunday.--Bruno Mulé
Source: Buffalo Bills
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Oct 2, 2026, 3:26 PM ET

Kansas City Chiefs kicker Harrison Butker will face the Las Vegas Raiders on the road in Week 4. Butker has now missed field goals in back-to-back games, but has not missed an extra-point attempt all season. The Chiefs will have their work cut out for them against a tough Raiders defense, so Butker should play a vital role in the matchup. Butker is ranked K5 in our RotoBaller Week 4 rankings, making him one of the best options to start at the position this week. The Chiefs kicker should be depended upon throughout the game and fantasy managers should feel confident with him in their lineups, despite his recent struggles.--Joshua Costello
Source: ESPN.com
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Oct 2, 2026, 3:23 PM ET

Kansas City Chiefs wide receiver Tyquan Thornton will face the Las Vegas Raiders in Week 4. Thornton has been the de facto deep threat option for quarterback Patrick Mahomes this season and his skill set may be necessary against a divisional opponent this week. Thornton recently caught two passes for 22 yards in the 24-10 win over the Miami Dolphins, but flashed more upside in the previous week with a closer game. In a 33-30 overtime win against the Indianapolis Colts, Thornton had four catches for 86 yards with a long catch of 45 yards in the contest. The Raiders defense has been stingy to start the season, so a big play or two may be necessary to take the top off the defense. Thornton is ranked WR70 in our RotoBaller Week 4 PPR rankings, making him a desperate flex option. Fantasy managers starting Thornton this week will need to hope for a deep catch or a score to salvage his day.--Joshua Costello
Source: ESPN.com
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Oct 2, 2026, 3:22 PM ET

Kansas City Chiefs wide receiver Xavier Worthy will face the Las Vegas Raiders on the road in Week 4. Worthy's performance in the 24-10 victory over the Miami Dolphins last week raised more concerns than optimism for his future performances. Worthy reeled in two catches for 20 yards on two targets in the contest. Despite the easy matchup, the third-year wideout finished with fewer yards and targets than Noah Gray in Week 3. Worthy will now have to face a tough Raiders defense in a matchup of two undefeated AFC West teams. Worthy will be involved in this week's matchup, but just how involved he will be is anyone's guess. Worthy is ranked WR60 in our RotoBaller Week 4 PPR rankings, making him a deep league flex option. Fantasy managers suffering from injuries may have to throw Worthy into lineups, but in most cases, there should be better options available.--Joshua Costello
Source: ESPN.com
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Oct 2, 2026, 3:20 PM ET

Tampa Bay Buccaneers quarterback Jalon Daniels will make his first career start against the Green Bay Packers in Week 4. Daniels will likely be under center for a few weeks with Baker Mayfield (thumb) out for at least three weeks. Daniels won the backup gig in camp, but he went undrafted out of Kansas. He has a decent arm and scrambling upside, but it's probably not enough to contribute legitimate fantasy value. Mayfield was struggling to find success, so it's unlikely that Daniels would be any better. He has a decent matchup against the Packers defense, but Daniels shouldn't be viewed as anything more than a desperation deep league play for Week 4.--Andy Webb
Source: Pro Football Reference

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