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DraftKings NFL DFS Lineup Picks for Week 1

Welcome to Week 1 of the 2018 NFL season. Congratulations, we finally made it through the long and tedious offseason. There are tons of contests on both major DFS sites to open the season. Below are my DraftKings DFS Lineup Picks for Week 1.

These DraftKings lineup recommendations are based on matchups, 2017 performances, overall upside/talent levels, opportunity, and other factors such as Vegas odds, home field advantage, and more. There are quite a few great value plays available, so read on to find out which players are the best for Week 1.

Good luck with your DraftKings DFS lineups!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 1 Picks

Andy Dalton - CIN @ IND (DK $5,800)

Until they prove me otherwise the Colts defense is a unit I am going to go against a lot early in 2018. Their pass rush is weak, they are relying on Jabaal Sheard and their 2018 second round pick out of Rutgers to make something happen. In addition neither of their corners are household names and shouldn’t be able to do much to prevent Dalton picking them apart if he has time in the pocket. Last season they gave up the eighth most points to quarterbacks on DraftKings, surrendering 23 touchdowns and over 4,000 yards. Dalton did not have a great season last year and his offensive line had its problems, although the Bengals have taken steps to address that this season. However, against this Colts defense he should get enough tme in the pocket to find A.J. Green and even take some deep shots for John Ross.

Philip Rivers - SD vs KC (DK $6,400)

The Chiefs also struggled against quarterbacks last year, surrendering 18.4 points per game, the 10th worst. They traded away their best corner in Marcus Peters and replaced him with Kendall Fuller. Fuller had a decent season last year but he also had a poor rookie season, so it will be interesting to see which Fuller shows up against Keenan Allen this week. The other defensive backs, outside of Eric Berry, are nothing to get excited about and Rivers should be able to have his way with this Chiefs defense. Finally, the over/under for this game is fairly high at 48, and the Chargers are going to need to keep putting up points if they are to stick with this potentially explosive Chiefs offense.

 

DraftKings DFS Running Backs - Week 1 Picks

James Conner - PIT @ CLE (DK $4,500)

Quite simply Le'Veon Bell does not look he is going to be available for this game. Last time Bell missed significant time, due to a knee injury, his replacement, DeAngelo Williams, finished fourth in fantasy points at the RB position that season. Conner is not DeAngelo Williams but he is a young running back in a Steelers system that is set up for running backs to succeed. With the weapons the Steelers have outside, the Browns will not be able to load the box and Conner should be able to gain decent yards regularly in this game. $4,500 for a number one running back is a bargain too good to pass up, especially in cash games. In GPP then you may want to fade Conner as he will likely be an extremely popular option this week.

Alex Collins - BAL vs BUF (DK $5,600)

The Buffalo Bills were on average a point and a half a game worse against running backs than any other team. When the Ravens committed to Collins last year and gave him over 15 carries he rewarded fantasy owners with an average of 17 points per game. Collins is going to enter this game as the number one. With Baltimore favorites by around seven points in most places, I expect to see him get a lot of carries in order to put the game away in the third and early fourth quarter

 

DraftKings DFS Wide Receivers - Week 1 Picks

A.J. Green - CIN @ IND (DK $7,800)

Whether you play Green or not probably comes down to whether you feel comfortable stacking your QB and wide receiver. I spoke above about the Colts defense against the pass, well against wide receivers they ranked 11th worst, surrendering 33.8 points per game on DraftKings. I do not expect either of the Colts corners to be able to shut Green down, and he is going to be Dalton's first choice of target all game long.

Ted Ginn Jr. - NO vs TB (DK $4,300)

Ginn offers interesting upside this week. Last season the Buccaneeers were the worst team in terms of fantasy points given up to opposing wide receivers. With Brent Grimes likely to matchup on Mike Evans, that leave Ginn likely covered by Vernon Hargraves, which should be a matchup he can have success with. Last season, Ginn had three of his four touchdowns at home and averaged 11 points more a game when playing in New Orleans. The over/under for this game is 51, so we should see plenty of points and the Saints do not often take their foot off the gas when they are playing at home.

 

DraftKings DFS Tight Ends - Week 1 Picks

Jack Doyle - IND vs CIN (DK $4,100)

Doyle has generally be an incredibly reliable tight end when it comes to catching the ball, with a catch rate for his career around 75%. He now gets to play with Andrew Luck once again, which can only boost his value. One thing that goes heavily in his favor is that Luck does not really have any outside targets he can truly trust other than T.Y. Hilton. Luck is going to need a regular outlet option and I expect Doyle to be that guy. The only concern is that he may lose redzone targets to Eric Ebron but otherwise I expect a solid week for Doyle, facing the team who ranked ninth worst against tight ends in 2017.

 

DraftKings DFS Defenses - Week 1 Picks

Baltimore Ravens vs Buffalo Bills (DK $3,800)

If you are playing GPP this one might be a little bit too obvious but the Ravens defense is extremely hard to pass up. Last time Nathan Peterman started a road game he threw five interceptions in 14 attempts. Now he has to go into Baltimore, with limited receiving options and question marks over his running back. I expect the Ravens to have a field day against the Bills offense and could have multiple interceptions. That high ceiling combines with a high floor because this Bills offense is not going to cut loose and open up. They will likely look to play a ball control offense, limiting the damage they can do on the scoreboard.

 

More Weekly Lineup Prep




REAL-TIME FANTASY NEWS

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Trevor Story

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Brandon Aiyuk

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Deebo Samuel Sr.

Now Only a Gadget Player/Kick Returner?
Elic Ayomanor

Offseason Additions Hurt Elic Ayomanor's Dynasty Outlook
Tyler Warren

a Clear Top-Five Dynasty Tight End
Jonathon Brooks

a Dynasty RB to Target Despite Injury History?
Blake Snell

Likely to Need Elbow Surgery
Tyler Allgeier

Currently in a Dynasty Buy Window Amid Rollercoaster Offseason
A.J. Brown

Timing Becoming Key to Acquiring A.J. Brown in Dynasty
Quentin Johnston

Is Quentin Johnston on the Verge of a Dynasty Breakout?
Jahmyr Gibbs

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Isaiah Likely

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Duncan Robinson

Nets 14 Points With Four Triples
Cade Cunningham

Contributes 21 Points in Game 6 Win
Jalen Duren

Bounces Back With Double-Double
Anthony Edwards

Finishes Season-Ending Loss With 24 Points
Victor Wembanyama

Tallies 19 Points in Friday's Win
De'Aaron Fox

Highly Effective in Blowout Win
Stephon Castle

Shines in Series-Clincher
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Austin Reaves

Could Command $40M Per Year With New Contract
Jalen Duren

Available to Finish Game 6
Yanic Konan Niederhauser

Not Expected to Be Ready for Start of Next Season
Jalen Williams

Declares Himself Healthy for Conference Finals
Terrence Shannon Jr.

Will Play Friday Night
Kevin Huerter

is Available for Game 6
Duncan Robinson

is Returning for Game 6
Caris LeVert

is Cleared for Game 6 on Friday
OG Anunoby

Practices in Full on Friday
Terrence Shannon Jr.

is Tagged as Questionable for Friday
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Luther Burden III

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MarShawn Lloyd

Can MarShawn Lloyd Emerge as a Top Dynasty Handcuff Option?
Emanuel Wilson

Can Emanuel Wilson Carve Out a Consistent Role in Seattle?
Max Fried

Heading to Injured List With Elbow Bone Bruise
Jaylin Noel

Playing-Time Outlook in Houston Remains Unclear
Dylan Sampson

Role in Cleveland Looks Secure Heading into 2026
Kirk Cousins

' Dynasty Value Fading Ahead of First Season in Las Vegas
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Julian Sayin Looking To Build Off Of Strong Debut Season
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College GameDay Set for First Three Weeks
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Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
George Holani

Dynasty Outlook Remains Cloudy
Jordan Westburg

to Have Season-Ending Elbow Surgery
Kendre Miller

Quickly Fading From Fantasy Relevance
Keon Coleman

Is Keon Coleman a Hopeless Dynasty Asset?
Marvin Harrison Jr.

a Buy-Low Candidate in Dynasty Formats
Melquizael Costa

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Arnold Allen

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Daniel Santos

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Juan Diaz

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Malcolm Wellmaker

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Modestas Bukauskas

Looks To Get Back In The Win Column
Tarik Skubal

Resumes Playing Catch, Ahead of Schedule?
Karl-Anthony Towns

Making an Impact as Playmaker in Playoffs
Jalen Duren

Determined to Improve
Kevin Huerter

Tagged as Questionable for Game 6 Against Cavaliers
Caris LeVert

Considered Questionable for Friday
Lane Hutson

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Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
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Carter Hart

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Pavel Dorofeyev

Enjoys Second Consecutive Multi-Goal Game
Shea Theodore

Records Two Points in Game 6 Win
Mitchell Marner

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Ryan Johnson

Takes Over as Canucks GM, Sedins Promoted to Co-Presidents
Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Quinn Hughes

Finishes Postseason With 15 Points
Matt Boldy

Posts Two Assists in Season-Ending Loss
Scott Wedgewood

Perfect in Relief Effort
Martin Necas

Records Another Multi-Point Game
Brett Kulak

Sends Avalanche Into Conference Finals
Brayden McNabb

Suspended for One Game
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
Juan Soto

Exits Wednesday's Game Early with Ankle Injury
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

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NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
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ACC, Big 12 Support 24-Team College Football Playoff
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Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
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