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DraftKings Daily Fantasy Baseball Picks (5/22/19): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on May 22nd, 2019. Austyn Varney's MLB DFS analysis and sleepers for building optimal DFS rosters.

Tonight's main slate starts at 7:05pm eastern and covers 11 games. There's also an all day slate starting at 1:05pm eastern that includes a few extra early games. We'll be focusing on the main slate, where we have plenty of pricey options to look through and some value plays to fit in as well. Let's dive in to each position!

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 5/22/2019. These picks will range from some of the elite players to mid-priced options and value plays.

We also provide DFS lineup picks for DraftKings and other sports. If you have any questions or comments, feel free to contact me on Twitter @varneydfs.

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DraftKings DFS Pitchers

Gerrit Cole, HOU (vs. CWS) ($12,000)

Gerrit Cole, Max Scherzer, and Jacob deGrom make up your top three pitching options. Scherzer and deGrom will be dueling and neither are a clear favorite. Cole on the other hand, is an insane -350 favorite. That’s as big as it gets in baseball. The White Sox aren’t a terrible team, but rank 17th against right-handers and strikeout at a healthy 26% clip. Gerrit Cole has been great over his last few starts and this isn’t the matchup to mess up his groove. Cole is expensive, but the top option in both formats if you can fit him.

Max Fried, ATL (@ SFG) ($8,500)

If you’re wanting to save a few dollars for your SP2, look no further than Max Fried. Fried can be a bit up and down, but he’s held both lefties and righties under a .285 wOBA. He’s striking out 8.5 batters per nine and has his command under control down to 1.5 BB/9. He enters one of the biggest ballparks in the game in AT&T Park to face off with an underwhelming Giants lineup that strikes out and struggles to hit for power. The Braves are favorites on the road and I could see a big day out of Fried for an affordable tag.

 

DraftKings DFS Infielders

C - Gary Sanchez, NYY (@BAL) ($5,500)

It doesn’t get much worse than Dan Straily. Through 8 starts this season, he’s gone 30.2 innings and has given up 29 earned runs. He now faces a tough Yankees lineup that has been hitting well without their best players. Gary Sanchez is still around, though, and he’s making his presence known. He may be expensive, but he’s so much stronger than any other catcher and has legitimate 2-HR upside every night. If you don’t want to spend much at the position, Buster Posey is always worth a look against a lefty.

1B - Yuli Gurriel, HOU (vs. CWS) ($3,900)

It’s starting to look like the career of Ivan Nova is coming to a close. Unless he dramatically changes his approach, he’s not going to last long. He’s been teed off on by both sides of the plate and hasn’t shown any signs of unluckiness or regression. He now faces off with the Astros, who’ll give him no break. If you want to save at 1B, Yuli Gurriel is consistent and will get a ton of RBI opportunities. He’s also only $3,900 on DraftKings and gives you cheap exposure to the top offense of the night. You can play him at third as well.

2B - Starlin Castro, MIA (@ DET) ($2,900)

Starlin Castro is extremely cheap on DK and I don't see the reason for it. Yes, he's not the greatest hitter, but he's in the heart of a Marlins lineup that's projected to put up 4.5 runs tonight. Castro has also always destroyed lefties. He's currently sporting a .390 wOBA and has shown no signs of slowing down. Daniel Norris has struggled against righties and the Marlins are better against southpaws. Castro and Anderson are both extremely cheap and I love pairing them with a more expensive combo from another team.

SS - Jorge Polanco, MIN (@LAA) ($4,700)

Jorge Polanco is one of my favorites hitters in baseball to roster. He seems to always com through in one way or another, and always has a big game when the Twins put up runs. He’s hitting .335 on the season with 8 home runs and a .400+ wOBA. Tonight, he faces off against Matt Harvey and the Angels. Harvey has been pitiful against lefties, allowing a .395 wOBA and 7 homers in just over 40 innings. The Twins are a juggernaut offense and Polanco himself is a tough out every time. As a switch-hitter, he always has the platoon advantage and will never see huge mismatch. He’s expensive, but cheaper than a lot of the other SS’s and he shouldn’t be. He’s my favorite of all, no matter the price.

3B - Alex Bregman, HOU (vs. CWS) ($5,500)

Bregman is expensive, but he may be worth paying up for on this slate. He’s one of the all-around best hitters in baseball and has slaughtered righties with a .427 wOBA followed by 11 homers. Ivan Nova will be lucky to last four innings tonight and it’s safe to expect five at-bats out of the Astros tonight. Now can Nova go through a CGSO? Yes, it’s baseball, but the Astros have the highest implied total on the night and are certainly safe to plant your flag on. If you want to go cheap here, just move to Gurriel.

 

DraftKings DFS Outfielders

OF - Mike Trout, LAA (vs. MIN) ($5,700)

If you’re going to pay up for an outfielder, Mike Trout is facing off against a lefty that likes to throw low in the zone. We know Trout lives in the lower third and he will make Perez pay for every mistake he makes. Perez has been pretty good this year on the surface, but a 4.23 xFIP and .263 BABIP tell a different story. He’s been a bit lucky, but by no means bad. He’s just no match for Mike Trout, who’s sported a .400+ wOBA against lefties for years now. There isn’t a ton of money to spend for fun on this slate, but Trout is the way to go if you can and I doubt he’s higher than 10% owned.

OF - Josh Reddick, HOU (vs. CWS) ($4,400)

We’ll close out our Astros love with Josh Reddick. For whatever reason, he’s cheaper than Marisnick and lets you spend up elsewhere while maintaining huge upside. It’s not like Reddick is having a bad year, either. His power numbers are a bit off, but he’s had four hit the warning track and could easily be at 8. Ivan Nova has always struggled against lefties, but a .425 wOBA is just unacceptable. He doesn’t have a strikeout pitch and can’t hold a runner. The Astros are the top offense of the night and it just comes down to fitting them in. There’s a reason for the price.

OF - Brian Anderson, MIA (@ DET) ($3,100)

This one may come out of left field, or third base, but you know what I mean. Brian Anderson has cooled off from his rookie season, but is still holding a wOBA over .340 against lefties. He has a power stroke and is the most consistent bat in the lineup with RISP. Daniel Norris is terrible against right-handers and struggles with the long ball. The Marlins aren’t a very exciting offense, but they’re better against lefties and Anderson has been swinging the bat nicely. He’s also extremely cheap and has solid positional versatility.

MLB DFS News and Injury Alerts




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REAL-TIME FANTASY NEWS

Jorge Polanco

Declines his 2026 Option to Become a Free Agent
Darius Garland

Set to Suit Up On Wednesday
Anthony Edwards

Back in Action on Wednesday Night
Zach LaVine

Ruled Out Versus Golden State
D'Andre Swift

Says he Will Play in Week 10
Jimmy Butler III

Sidelined Versus Sacramento
Domantas Sabonis

Sidelined on Wednesday
Brandon Aiyuk

49ers "Pretty Confident" Brandon Aiyuk Will Play This Year
Adam Gaudette

Available Against Kraken
Anthony Edwards

Probable for Wednesday's Matchup With Knicks
Scott Laughton

Set for Season Debut Wednesday
Justin Brazeau

Ruled Out for Four Weeks
Tristan Jarry

Expcted to Miss Three Weeks
Quinshon Judkins

Not on the Week 10 Injury Report
Johnny Furphy

Unavailable Wednesday
Conor Garland

Returns Against Blackhawks
Puka Nacua

Should Play in Week 10
Rasmus Sandin

Back for Capitals Wednesday
Trey Benson

Not Practicing Wednesday, Cardinals Taking it Day by Day
Denton Mateychuk

Out on Wednesday
Quenton Jackson

Unavailable on Wednesday
RayJ Dennis

Probable For Wednesday
Tobias Harris

Remains Out With Ankle Injury
Walker Kessler

Out For The Season
Ka'imi Fairbairn

Not Expected To Play in Week 10
Davis Mills

C.J. Stroud Will be Out in Week 10, Davis Mills to Start
Kyler Murray

Heading to Injured Reserve
TreVeyon Henderson

on Track to Lead Backfield in Week 10?
Rico Dowdle

Dealing With Quad Injury, Officially Misses Practice
Garrett Wilson

at Practice Wednesday After Missing Last Two Games
Chris Sale

Braves Picking Up Chris Sale's 2026 Option
Ray Davis

Could Have Expanded Role in Week 10
Jayden Daniels

Commanders Still Evaluating Jayden Daniels' Elbow Injury
Brian Thomas Jr.

Not Seen at Practice on Wednesday
James Cook

to Miss Practice With Ankle/Foot Injury
Michael Thorbjornsen

Poised to Continue Hot Play in Mexico
Davis Riley

Struggling to Find Form Ahead of World Wide Technology Championship
Taylor Montgomery

Leaning on Putter at World Wide Technology Championship
Stephan Jaeger

Offers Strong Value at World Wide Technology Championship
Ben Griffin

Looks to Stay Hot at El Cardonal
Nick Dunlap

Looking to Find His Game at El Cardonal
Wyndham Clark

Searching for Consistency at El Cardonal
Michael Brennan

Aims to Extend Fairytale Start at El Cardonal
Nathan MacKinnon

Extends Point Streak to Seven Games
Akira Schmid

Posts First Shutout of the Season
Jack Roslovic

Takes Point Streak to Four Games
Wyatt Johnston

Records Three Assists Against Oilers
Trevor Zegras

Dishes Out Two Assists in Tuesday's Win
Darcy Kuemper

Shuts Out Jets With 23 Saves
Cutter Gauthier

Erupts for Four Points Against Panthers
Zach LaVine

Questionable to Face Warriors
Domantas Sabonis

Iffy for Wednesday
Austin Reaves

Considered Questionable for Wednesday
Luka Dončić

Luka Doncic Available Wednesday
Anthony Davis

Remains Out Wednesday
Jimmy Butler III

Expected to Miss Wednesday's Game
Stephen Curry

Won't Play on Wednesday
Shane Bieber

Staying in Toronto for 2026
Salvador Perez

Agrees to Two-Year Extension With Royals
Gustav Nyquist

Jets Move Gustav Nyquist to Injured Reserve
Noah Hanifin

Expected to Return From 10-Game Absence Tuesday
William Eklund

to Remain Out Wednesday
TB

Max Crozier Available Tuesday
Tristan Jarry

Lands on Injured Reserve
Jason Zucker

Placed on Injured Reserve
Trevor Story

Opts in for Remaining Two Years on his Contract
Pyotr Kochetkov

Starts on Tuesday
Luguentz Dort

Available on Tuesday
Yu Darvish

to Miss All of 2026 Following Flexor-Tendon Surgery
Jacoby Brissett

to Start Again in Week 10
Anthony Edwards

Considered Questionable For Wednesday
Yves Missi

Out Tuesday
A.J. Brown

Won't be Traded at Deadline
Garrett Wilson

"Untouchable" in Trade Talks
Shota Imanaga

Becomes a Free Agent
Luis Robert Jr.

White Sox Pick Up 2026 Option on Luis Robert Jr.
CFB

LJ Martin Expected to Play in Top-10 Matchup Against Texas Tech
PGA

LIV Golf Expanding To 72-Hole Format In 2026
Rashid Shaheed

Being Shipped to the Seahawks
Sauce Gardner

Colts Acquiring Sauce Gardner From the Jets
Travis Hunter

Not Expected to be Out Long-Term
Atlanta Braves

Braves Hire Walt Weiss as Their Next Manager
Kris Bubic

Cleared to Begin a Throwing Program
Brandon Woodruff

Declines Mutual Option for 2026
Freddy Peralta

Brewers Exercise 2026 Option on Freddy Peralta
Lucas Giolito

Declines his 2026 Player Option
J.J. Spaun

Finishes Sixth at Procore Championship
PGA

Matti Schmid Finishes Tied for 46th at Baycurrent Classic
Keith Mitchell

Finishes Tied for 10th at Baycurrent Classic
Si Woo Kim

Finishes Tied for 21st at Genesis Championship
Mackenzie Hughes

Misses The Cut at Sanderson Farms Championship
Max Greyserman

Finishes Second at Baycurrent Classic
Austin Eckroat

Finishes Tied for 56th at Baycurrent Classic
Luke Clanton

Finishes Tied for 56th at Bank of Utah Championship
Pete Alonso

Officially Opts Out of his Contract With Mets
Alex Bregman

Opts Out of his Contract With Boston
Edwin Díaz

Edwin Diaz on the Open Market This Winter
Cody Bellinger

Becomes Free Agent After Opting Out
Robert Suarez

Opts Out, Becomes Free Agent
Kyle Larson

Wins His Second NASCAR Cup Series Championship at Phoenix
Ryan Blaney

Concludes the 2025 Season with A Win at Phoenix
William Byron

Strong Championship Effort Ends With Late-Race Flat-Tire Crash
Denny Hamlin

Overtime Four-Tire Call Costs Denny Hamlin the Championship
Chase Briscoe

Championship Bid Never Really Started After Two Tire Failures
Brad Keselowski

Nearly Steals Phoenix Race
David Onama

Suffers First-Round TKO Loss
Steve Garcia

Scores First-Round TKO Win
Ante Delija

Suffers His First UFC Loss
CFB

Dylan Raiola Suffers Season-Ending Injury
Waldo Cortes-Acosta

Gets Knockout Win
Themba Gorimbo

Drops Decision At UFC Vegas 110
Jeremiah Wells

Gets Back In The Win Column
Yadier del Valle

Remains Undefeated
Isaac Dulgarian

Cut By UFC Following Submission Loss
Daniel Frunza

Still Winless In The UFC
Charles Radtke

Dominates Daniel Frunza
Allan Nascimento

Gets Submission Win
Cody Durden

Suffers Second-Round Submission Loss
Max Scherzer

Doesn't Plan on Retiring
Michael King

Becomes Free Agent After Declining Mutual Option
Austin Cindric

is A Driver to Avoid for Phoenix DFS Lineups
Yoshinobu Yamamoto

Named World Series MVP
Alex Bowman

Could Alex Bowman be A Sneaky Tournament Play for Phoenix?
Noah Gragson

Should DFS Players Roster Noah Gragson At Phoenix?
Erik Jones

Is Erik Jones Worth Rostering for DFS at Phoenix?
Michael McDowell

an Easy Recommendation for DFS at Phoenix
Chase Briscoe

Probably Won't Win the Title
Joey Logano

Could Play Spoiler in Championship Battle at Phoenix
Tyler Reddick

Seeking to End Winless Drought, but Probably Won't Have the Speed
NASCAR

Bubba Wallace Looks to Protect Top-10 Points Finish at Phoenix
Brad Keselowski

Hasn't Been Fast at Phoenix With RFK Racing
Daniel Suarez

With Nothing at Stake, Expect Little From Daniel Suarez
Kyle Busch

Qualifies Well, but Will Probably Finish Worse Than he Starts
Chris Buescher

Ryan Preece has a Shot to Overtake Chris Buescher as RFK Racing's Lead Driver
Austin Dillon

Looks to Avoid Finishing Last in NASCAR Playoffs
AJ Allmendinger

A.J. Allmendinger Might be a Worthy DFS Option
David Onama

Set For UFC Vegas 110 Main Event
Steve Garcia

Returns At UFC Vegas 110
Waldo Cortes-Acosta

Set For Co-Main Event
Ante Delija

In Search For His Second UFC Win
Themba Gorimbo

A Favorite At UFC Vegas 110
Jeremiah Wells

Looks To Return To The Win Column
Yadier del Valle

Looks To Remain Undefeated
CFB

Arizona State Quarterback Sam Leavitt Out for the Season
Isaac Dulgarian

Looks To Win Back-To-Back Fights
Daniel Frunza

Looks For His First UFC Win

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP