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FanDuel MLB DFS Lineup Picks (5/25/21): Daily Fantasy Baseball Advice

juan soto fantasy baseball rankings outfield MLB injury news

Mark Strausberg highlights the top FanDuel MLB DFS lineup picks for 5/25/21, and a couple of sleepers to consider while building daily rosters.

Welcome RotoBallers to another set of Tuesday FanDuel lineup picks! It is another heavy slate of games on the main slate tonight. There is just two early evening game in the 6 o'clock ET hour and then everyone else is playing in the main slate. If you have questions about that early game, feel free to hit me up on Twitter with questions (@MarkStrausberg).

With so many games though in the main slate, the focus will be on the main slate. Read below to find out what player I will be suggesting for your lineups, as I provide my daily fantasy baseball lineup picks for the FanDuel main slate on 5/25/2021. 

Be sure to also check out all the MLB player news, including late scratches, and the projected and confirmed daily MLB lineups for each DFS slate. You can also check out today's DraftKings MLB DFS lineup picks, and read more DFS advice and lineup picks for other sports too. With that out of the way, here are my picks for tonight.

Featured Promo! Save 30% on any Premium Pass using discount code NEW. Win more with our DFS, Betting and Season-Long Pass, get expert tools and advice from proven winners! GAIN ACCESS

 

FanDuel DFS Pitchers

Cash Game/GPP Anchor Play:

Cole Irvin - OAK vs SEA ($7,200)

With a salary of under $7500, I expect Irvin to be a pretty popular option on Tuesday night. However, this is a big slate, which will naturally disperse some of the ownership. Furthermore, his ownership rate might be a little deflated after his last outing. It was absolutely his worst outing of the year. He gave up five runs, gave up twice that number of hits and walks, and struck out just one batter. And he still went five innings. If your worst outing is a 9.00 ERA and 2.00 WHIP, that's not too shabby. Despite those combustible ratios, Irvin still has a 3.59 ERA and 1.17 WHIP this year.

He's been a little on the lucky side to be honest and we could have seen his last outing coming. Houston is second in the league in runs, tops in batting average, and as they have been for a few years now, the Astros are a tough match-up. But few things are better for what ails than you than a visit from the toothless Tigers. The Tigers are bottom five in nearly every hitting category. If you want to get technical, we can say the exception is strikeouts, where they are not actually bottom five as they have whiffed the third most times! You get the point. Add in the likely win, Irvin is an easy play.

GPP Play

Chi Chi Gonzalez, COL vs NYM ($5,500)

I was originally going to have Jacob deGrom in this space, as a pitcher making his first start off the DL and costing $12K should be enough to limit his exposure. However, I suspect deGrom will be a very popular pick, thereby making him a poor GPP choice with so many other great options on Tuesday night. But then I started looking at the other side of the game. Do you realize how bad the Mets have been offensively this season?

The Mets are tied with Pittsburgh for the fewest HRs. Some of that is because they have played less games than most clubs. Yet they are 11 dingers behind the next closest team. They have the fewest runs by far in the league as they are 16 runs behind Pittsburgh. But let's not blame simply the number of games as the reason, as they're not even averaging 3.5 runs a game. We can ignore the cumulative categories if you wish and you still find the Mets near the bottom in every percentage category as well. And it's not like the Mets stadium is like hitting in Colorado either.

And that brings us to Rockies pitcher Gonzalez, who has been better than you might think. He recently shut down the Padres, giving up just two earned runs in six innings and striking out six. Before that, he had his best outing of the year. He blanked the Reds for seven frames in Colorado. He has only six walks in his last 31 2/3 IP.

Gonzalez is not going to suddenly pitch a no-hitter or even strike out a dozen batters. But he's been pitching well lately. He should give us a tidy profit and leave us plenty of salary to spend on the bats on a night where offense should be more limited.

Editors Note: Gonzalez has been bumped and Kyle Freeland will now be starting for the Rockies. NYM are still a nice match-up!

 

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's RealTalkRaph on DraftKings - join in on the winning!

 

FanDuel DFS Infielders

Matt Olson - 1B, OAK vs SEA ($3,600)

We start with the left-handed Olson, who has a dozen dingers and is facing off against the right-handed Gilbert and his 9.45 ERA. Olson is not cheap, but he doesn't break the bank. Sometimes lineup decisions are just that easy.

Nick Solak - 2B/OF, TEX at LAA ($2,700)

I'll be honest with you, I'm getting as weary of recommending Solak as you likely are about me recommending him. But the fact remains that Solak is having a solid 2021 campaign (.258 with eight HRs and two SBs). Furthermore, today is a decent day to play him since he has a dozen ABs vs. Andrew Heaney so far this year and is hitting a robust .417 against him this year.

Rafael Devers - 3B, BOS vs ATL ($3,800)

I can't help but spend up at 3B, where Devers continues to be one of the hottest players in baseball with 13 HRs, including two already this week. He'll be squaring off against Charlie Morton, who can't pitch worth his salt right now. (Morton. Salt. Get it? Oh, my talents are wasted on you....). But this is just not a fair match-up. Or is it? In 23 ABs, Devers is hitting .263 against Morton, which is below his season average. However, I remind you that Devers has a .943 OPS this season and expect the tide to move towards Devers.

Isiah Kiner-Falefa- SS/3B,  TEX @ LAA ($2,400)

I love IKF as a salary saving option. He has double-digit swipes already, but he's not some just speed no pop kind of player. In his last 15 games he is slugging .439. The right-handed IKF is going against the left-handed Heaney. The aforementioned Heaney has a 5.31 ERA and has allowed ten runs over his last 8.33 innings.

 

FanDuel DFS Outfielders

Jurickson Profar - OF, SDP vs MIL ($2,300) 

An even cheaper option is Profar, who seems to be coming out of his slump. In his last seven games, he is hitting .296. You don't get a player with multiple 20 HR seasons for $2300 too often. Grab Profar now while he is still cheap.

Austin Meadows - OF, TBR vs KRC ($3,900)

Saving money on Profar allows us to spend up elsewhere in the OF. I'll take Austin Meadows against Brad Keller and his 6.62 ERA. Meadows last failed to get on base over ten days ago. And he's been absolutely crushing the ball the last week:

Juan Soto - OF, WSH vs CIN ($4,000)

I saved the best for last as Soto is the real jewel of my lineup however taking on Tyler Mahle and his highly combustible ERA of 4.31 Soto only has three at-bats against Mahle this year, but in those three at-bats he's hitting .667 with a round-tripper. I don't need to convince you Soto is a good play today, do I?

Good luck with your entries!



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REAL-TIME FANTASY NEWS

Bryan Abreu

Could Begin Season as the Closer
Justin Foscue

Exits Early with Hamstring Tightness
Trevor Megill

had Offseason PRP Injections
Merrill Kelly

is Awaiting MRI Results
José Berríos

Jose Berrios Feels Fully Healthy Now
CFB

Gunner Rivers Follows His Father, Commits To North Carolina State
Anfernee Simons

Ruled Out Tuesday
Pascal Siakam

Doubtful for Tuesday
Los Angeles Chargers

Bradley Bozeman Announces his Retirement
Joel Embiid

Questionable Vs. Pacers
Jaylen Brown

Considered Questionable for Tuesday
Ty Jerome

Unlikely to Play Monday
Cooper Flagg

Set to Miss Tuesday's Matchup With Nets
Devin Carter

Downgraded to Out Vs. Grizzlies
Scottie Barnes

Set to Face Thunder
Will Zalatoris

Set to Make Tournament Debut at Cognizant Classic
Jakob Poeltl

Out Tuesday Against Thunder
Ziaire Williams

Slated to Suit Up Tuesday
Dejounte Murray

Set to Debut Tuesday
Linus Ullmark

Available for Senators
Dillon Brooks

Set to Miss 4-6 Weeks
Jusuf Nurkić

Jusuf Nurkic to Undergo Season-Ending Nose Surgery
Rasmus Hojgaard

Trending Up at the Cognizant Classic
Ryan Reaves

Sharks Activate Ryan Reaves From Injured Reserve
Charlie Lindgren

Activated From Injured Reserve Monday
Josh Norris

Cleared to Return Wednesday
Max McGreevy

Will Need to Improve on the Greens to Compete
Rico Hoey

Returns to Cognizant Classic
Austin Eckroat

Looks to Bounce Back at Cognizant Classic
Aaron Rai

Bounces Back After Rough Start to 2026 Season
Shane Lowry

Continues Playing Well Heading to Cognizant Classic
Max Homa

Has Opportunity to Continue Building Momentum at the Cognizant Classic
Ryan Gerard

Strong Approach Play Behind his Hot Start in 2026
Luke Clanton

Making Fourth Start of 2026 at Cognizant Classic
Kevin Lankinen

Unlikely to Play Wednesday
Josh Morrissey

to Miss Start of Road Trip
Mikko Rantanen

Expected to Miss Time
Jared Jones

Aiming to be Ready in Late May
Matt Brash

Not Feeling Great After Tooth Removal
Tarik Skubal

to Make One Start in World Baseball Classic
Blake Snell

Opening Day Not a Target for Blake Snell
Hagen Smith

to Face Hitters on Tuesday
Brandon Woodruff

Opening Day "Up in the Air" for Brandon Woodruff
Dairon Blanco

Avoids Full Concussion
Andrew Putnam

Looks to Jumpstart His Season at Cognizant Classic
Adam Scott

Looks For Continued Success at PGA National
Anthony Hernandez

Suffers Third-Round TKO Loss
Sean Strickland

Gets Back In The Win Column
Kyle Pitts Sr.

Falcons Planning to Use Franchise Tag on Kyle Pitts Sr.
Geoff Neal

Suffers Back-To-Back Knockout Losses
Uros Medic

Shines At UFC Houston
Isaac Collins

Healthy After Receiving Knee Injections
Dan Ige

Gets Finished For The First Time In His Career
José Caballero

Jose Caballero Bringing More Bat Speed into 2026 Season?
Melquizael Costa

Extends His Win Streak To Six
Jackson Holliday

Doesn't Have his Hand Wrapped
NASCAR

Bubba Wallace Falls Short of Victory at EchoPark Speedway
Carson Hocevar

Rallies to Fourth At EchoPark Speedway After Early Struggles
Ross Chastain

Finishes Third At EchoPark Speedway
Chase Briscoe

Scores First Career Top-Five Finish at EchoPark Speedway
Tyler Reddick

Nabs His Second Win of the Season At EchoPark Speedway
Thairo Estrada

Orioles Agree to Minor-League Contract With Thairo Estrada
Josh Hader

Not Guaranteed to be Ready for Opening Day
Michael Conforto

Joins Cubs
Rayan Rupert

Signing 10-Day Contract with Grizzlies
Killian Hayes

Set for 10-Day Stint With Kings
Cason Wallace

Posts Career-High 10 Assists in Win
Santi Aldama

Sidelined Again Monday
Jaxson Hayes

Leaves Game After First-Quarter Injury
Deni Avdija

Leaves Game After Back Flare-Up
Payton Tolle

Allows One Run in Spring Training Debut
Jalen Smith

Exits Early In Loss to Knicks
Jacob Melton

Showcasing Power in Spring Training
Kyle Anderson

Likely Out Monday
Joey Logano

Will Be Popular DFS Pick at EchoPark Speedway
Tyler Reddick

on Pole After Qualifying Rained Out at EchoPark Speedway
Chase Elliott

Could Chase Elliott Be Worth Rostering At EchoPark Speedway?
Ryan Blaney

Is Ryan Blaney Worth Rostering for DFS at EchoPark Speedway?
William Byron

Is William Byron Worth Rostering for DFS at EchoPark Speedway?
Rondale Moore

Passes Away
Denny Hamlin

Is Worth Consideration for EchoPark Speedway DFS Lineups
Brad Keselowski

Is A Tournament Option for DFS At EchoPark Speedway
NASCAR

Is Bubba Wallace Rosterable In DFS At EchoPark Speedway?
Austin Cindric

Should DFS Managers Roster Austin Cindric at EchoPark Speedway?
Ross Chastain

Is Ross Chastain A Sneaky DFS Option for EchoPark Speedway?
Ricky Stenhouse Jr

Is Ricky Stenhouse Jr. Worth Rostering for DFS at EchoPark Speedway?
Alex Bowman

Will Start Towards the Rear At EchoPark Speedway
Javonte Williams

Cowboys Sign Javonte Williams to Three-Year, $24 Million Extension
Joel Armia

Wraps Up Olympics With Three-Point Performance
Daniil Tarasov

Available for Panthers
Evan Rodrigues

Set to Return Next Week
Aaron Ekblad

Expected to Play Thursday
Pavel Zacha

Cleared for Action
VAN

Jonathan Lekkerimaki Needs Season-Ending Shoulder Surgery
Mikko Rantanen

Misses Bronze-Medal Game With Lower-Body Injury
Blake Coleman

Activated From Injured Reserve
Matt Rempe

Heading to Injured Reserve After Second Thumb Procedure
Sidney Crosby

a Game-Time Call for Olympic Final
Josh Morrissey

Won't Play Sunday
Filip Chytil

Out Indefinitely With Facial Fracture
Connor McDavid

Makes History With Another Multi-Point Outing
Tage Thompson

Expected to Play in Olympic Final
Travis Etienne Jr.

has "Legitimate Interest" in Joining Chiefs
Zach Charbonnet

Undergoes Knee Surgery on Friday
CFB

Curt Cignetti Agrees to New Deal With Indiana, Will Earn $13.2 Million Per Year
Anthony Hernandez

Set For UFC Houston Main Event
Sean Strickland

Looks To Get Back In The Win Column
Uros Medic

Set For UFC Houston Co-Main Event
Geoff Neal

Looks To Get Back In The Win Column
Melquizael Costa

A Favorite At UFC Houston
Dan Ige

An Underdog At UFC Houston
Rashee Rice

Accused of Assault by Long-Time Girlfriend
Ben Griffin

Looking to Return to Top Form at Riviera
Keegan Bradley

Looking to Build Momentum at Riviera
J.J. Spaun

Putting a Major Concern at Riviera
Sepp Straka

May Have Tough Time at The Genesis Invitational
Shane Lowry

Trending Up Entering the Genesis Invitational
Justin Rose

Off Most Radars at The Genesis Invitational
Robert MacIntyre

a Long Hitter to Watch at Riviera Country Club
Jake Knapp

Red-Hot Heading to Riviera
Min Woo Lee

Attempts to Build Momentum After Pebble Beach
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