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FanDuel MLB DFS Lineup Picks (5/21/19): Daily Fantasy Baseball Advice

Austyn Varney highlights the top FanDuel MLB DFS lineup picks for 5/21/19, and a couple of sleepers to consider while building daily rosters.

Tonight's main slate starts at 7:05pm eastern and covers 14 games. There's also an all day slate starting at 6:05pm eastern that includes one extra early game.

In this article, I will be providing you with my daily fantasy baseball lineup picks for FanDuel on 5/21/2019. These picks will range from some of the elite players to mid-priced options and value plays.

We also provide DFS lineup picks for DraftKings and other sports. If you have any questions or comments, feel free to contact me on Twitter @varneydfs.

 

FanDuel DFS Pitchers

SP - Justin Verlander, HOU vs CHW ($12,000)

We have a ton of pitchers to look at on this slate, but Verlander certainly stands out. The White Sox are bad against righties, striking out 26% of the time and making up for it with a measly .315 team wOBA. Verlander is a top 5 arm in baseball and he hasn’t slowed this year. He’s still striking out 10+ batters per nine innings and has held both righties and lefties to a sub .250 wOBA. The Astros are the biggest favorites of the night and it’s not close. Verlander is a no-brainer cash game option and the top play overall. 

SP - Spencer Turnbull, DET vs MIA ($8,600)

If you’re wanting to save some funds at pitcher, Spencer Turnbull and the Tigers are facing off with the worst lineup in baseball. The Marlins not only rank 30th against righties (wOBA), but it’s by a huge margin. They’re one of the worst hitting teams in the least twenty seasons and we should be targeting them as often as possible. Turnbull is certainly volatile, but he strikes out 11+ righties per nine, so should be fine at his price even if he gives up a run or three. Caleb Smith May dominate the Tigers as well and this could be a low-scoring affair, but I think Turnbull holds his own. If you’re looking for safety, Caleb Smith will give you that for an extra 2k. 

 

FanDuel DFS Infielders

1B - Dan Vogelbach, SEA at TEX ($3,800)

Vogelbach is still affordable and there’s really no excuse for it. He has 13 homers on the season and is sporting a .443 wOBA against righties. The Mariners go into Arlington and face off with Lance Lynn, who holds a 4.75 xFIP against lefties and has a big HR problem. Arlington is a huge upgrade from Seattle for power and Vogelbach will look to add number 14 to the books tonight. He’s affordable and has as much HR upside as anyone. 

2B - Wilmer Flores, ARI at SD ($2,700)

Matt Strahm is not a bad pitcher by any means,  but his 4.16 xFIP is telling us that he’s been lucky so far. Wilmer Flores is a monster against left-handers and will be hitting in the three hole at just $2,700. In what’s been his worst year of the last three, Flores is still sporting a .364 wOBA with two homers. The Diamondbacks offense is solid and you have to figure Flores gets involved. At the incredible cheap price tag, I don’t see a batter way to go at a weaker position in second base. 

3B - Miguel Sano, MIN at LAA ($3,300)

Since coming back just five games ago, Miguel Sano has hit 2 home runs and is seeing the ball nicely. He’s going to fit in quite well with a lineup that’s really just missing a power bat. Sano and the Twins face off with Trevor Cahill, who’s probably the worst pitcher on the entire slate. He’s not only allowed a .341 combined wOBA, but 6 ER+ in two of his last three. The Twins beat Cahill up just four days ago and the Angels will send him back out to the wolves. Sano is the top play at third base and it’s not close when you see the price.

SS - Gleyber Torres, NYY at BAL ($3,600)

Torres is swinging the hottest bat on the Yankees, hitting safely 16 times in the last nine games. Gleyber has stepped it up for an injured Yankees team that needs the line drives and hard contact.  We haven’t touched on the Yankees yet, but they’re firmly in play with David Hess on the mound and the Orioles bullpen backing him up. Torres will have a couple RBI opportunities throughout and I have a sneaky suspicion that he won’t disappoint.

 

FanDuel DFS Outfielders

OF - Christian Yelich, MIL vs CIN ($4,700)

Moving onto the outfield, Christian Yelich will be our expensive bat. He seems to either hit a home run or get 3 hits against everyone, and it really just comes down to limiting damage. Sonny Gray has struggled mightily against lefties, holding a .347 wOBA since ‘18. Yelich on the other hand, has posted a .435 wOBA against right-handers. Pure domination. If you can afford him while still loving the rest of your lineup, there’s no better place to go.

OF - Eddie Rosario, MIN at LAA ($4,200)

If you need to save a couple hundred, Eddie Rosario is my choice. He’s a guy who will be in every lineup of mine, as I think he clobbers Trevor Cahill. Cahill can’t strike anyone out and has trouble finding a put away pitch. As for Rosario, he’s u stoppable when putting the ball in play. He drives it for power and often has ducks on the pond. The Twins are our favorite offense of the night and Rosario is their best outfielder. Kepler and Cave are in play too if they find the lineup. 

OF - Kyle Schwarber, PHI vs CHI ($2,700)

If you want to save some funds, Kyle Schwarber should be hitting leadoff for the Cubs against Zach Eflin. Eflin, who struggles against lefties, (.354 wOBA) should struggle with this potent Cubs lineup. Schwarber gives you great exposure for cheap and at a position where you’re not missing out on anything. He not only has individual HR upside, but also has rally upside if the Cubs get going as a squad. The Phillies bullpen is good, but got worn out yesterday and may have some holes in it. Schwarber is a great discounted piece and deserves consideration in cash games and tournaments.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Deshaun Watson

Hitting it Off With Todd Monken?
Jacoby Brissett

Not Present for First OTA Practice
Tua Tagovailoa

Michael Penix Jr. Splitting First-Team Reps at OTAs
Rashee Rice

Tests Positive for Marijuana, Violating his Probation
Cam Skattebo

Says he'll be Ready for Week 1
De'Von Achane

Present for Start of OTAs This Week
Malik Washington

an Affordable Trade Target in Dynasty Leagues
Patrick Mahomes

Is Patrick Mahomes Still a Top-Five Dynasty Quarterback?
Michael Trigg

Is There a Spot for Michael Trigg in Dallas?
Seth McGowan

in the Mix for Playing Time as a Rookie?
Audric Estimé

Audric Estime Droppable in Dynasty Leagues?
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
Kyren Williams

Have Timeshare Concerns Sunk Kyren Williams' Dynasty Value Too Low?
Ja'Marr Chase

Is Ja'Marr Chase the Most Valuable Player in Dynasty?
Javonte Williams

' Unusual Career Path Has Left Him Undervalued in Dynasty Leagues
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
Terry McLaurin

a Veteran Buy for Contending Dynasty Managers
CFB

Mark Bowman a Day 1 Impact Player for USC?
Tee Higgins

Becoming an Underappreciated Dynasty Asset
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
Alex Caruso

Erupts for 31 Points in Game 1 Loss to Spurs
CFB

Kemario Taylor a Breakout Candidate at Quarterback
Jalen Williams

Productive in Comeback Game
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
Shai Gilgeous-Alexander

Records First Double-Double of Postseason
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Stephon Castle

Opens Conference Finals With Double-Double
Dylan Harper

Makes Outstanding Two-Way Impact in Game 1 Win
Victor Wembanyama

Dominates Game 1 Against Thunder
Mattias Samuelsson

Picks Up an Assist in Season-Ending Loss
Rasmus Dahlin

Nets Fourth Postseason Goal
Jakub Dobes

Records 37 Saves in Game 7 Win
Lane Hutson

Contributes Power-Play Assist in Game 7 Victory
Nick Suzuki

Extends Road Point Streak
Alex Newhook

Scores Series-Clincher in Overtime
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Larry Nance Jr.

is Questionable for Game 1 on Tuesday
OG Anunoby

is Probable for Tuesday's Game 1
Luke Kornet

is Cleared for Game 1
New Orleans Pelicans

Jamahl Mosley Agrees to Become Pelicans Next Head Coach
De'Aaron Fox

is Ruled Out for Game 1 on Monday
Ukko-Pekka Luukkonen

Set to Start Game 7
Corey Seager

Going on Injured List With Back Injury
Tage Thompson

Can Match Franchise Record With Another Multi-Point Game
Nick Suzuki

Seeks More Road Success Monday
Lane Hutson

Riding a Five-Game Assist Streak Into Game 7
Filip Gustavsson

Needs Offseason Surgery
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Cam Skattebo

Dynasty Stock Rising Following NFL Draft
Kaleb Johnson

Logging First-Team Reps in OTAs
Evan Engram

Dynasty Value Fading After Production Decline in 2025
TreVeyon Henderson

Dynasty Outlook Clouded By Split Backfield in New England
Caleb Williams

' Dynasty Upside Remains Sky-High Entering 2026
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Tobias Harris

Goes Cold in Game 7 Loss
Quinn Hughes

Open to Signing Extension This Offseason
Jalen Duren

Finishes Game 7 with Quiet Line
Cade Cunningham

Endures Cold Shooting Night Sunday
Joel Eriksson Ek

Misses Second Round Due to Heel Injury
Sam Merrill

Catches Fire in Game 7 Win
Evan Mobley

Posts Versatile Double-Double in Game 7
Jonas Brodin

Sits Out Round 2 Due to Toe Injury
Donovan Mitchell

Guides Cavaliers Into East Finals
Sam Malinski

Practices Fully Sunday
Jarrett Allen

Scores 23 Points in Cavs' Game 7 Rout of Pistons
Josh Manson

Rejoins Practice
Kevin Huerter

Active on Sunday Night
Caris LeVert

Duncan Robinson, Caris LeVert Available Sunday
Dean Wade

Max Strus Replaces Dean Wade in Starting Lineup Sunday
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Max Fried

Heading to Injured List With Elbow Bone Bruise
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF