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DraftKings, FanDuel Daily Fantasy Basketball Picks (4/21/22): Today's Top NBA DFS Lineups

The top daily fantasy basketball lineup picks for DraftKings and FanDuel on April 21, 2022. Juan Carlos Blanco provides NBA DFS analysis and sleeper picks for building optimal DFS rosters.

We're primed for yet another three-game playoff slate tonight and another solid NBA DFS slate. We have three game threes on the docket tonight!

The Memphis-Minnesota series is knotted 1-1 heading into game three as is the Utah-Dallas series. Meanwhile, the Nuggets are fighting for their playoffs lives as they come home down 0-2 to the Warriors in game three of their series.

This article will provide you with my daily fantasy basketball lineup picks for DraftKings and FanDuel on 4/21/22. Remember to monitor the NBA injury report as the slate can completely change before lineup lock, which is at 7:30 pm ET tonight. Good luck, RotoBallers.

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DraftKings and FanDuel Guards - NBA DFS Lineup Picks

Ja Morant - PG, MEM vs. MIN ($9,800 DK; $9,900 FD)    

Morant looked all the way back from his recent knee injury in Game 2, shooting 56.3 percent on his way to a 23-point, 10-assist double-double that also included nine rebounds. The star guard is still shooting 38.9 percent overall against Minnesota in six meetings since the start of the regular season, but he's now eclipsed 50 DK points in each of the first two games of the series. The T-Wolves were an excellent defense at home this regular season, but there's naturally no double Morant will once again have a massive role and there's also a good chance Thursday's game comes right down to the buzzer after the double-digit margins of victory for each team in the first two games.

Donovan Mitchell - PG/SG, UTA vs. DAL ($8,400 DK; $9,000 FD)

Mitchell has overcome some shooting inefficiency with significant volume in the first two games of the series, as he's racked up 32 and 34 points while putting up a whopping 59 attempts. That's led to a pair of tallies over 40 fantasy points on each site, and the heavy involvement should naturally persist on Utah's home floor of Vivint Arena on Thursday. Mitchell was a slightly better shooter at home this season, posting a 44.8 percent success rate from the floor, including 36.0 percent from three-point range. He's averaging over 40 fantasy points on each site against the Mavs in six meetings since the start of the regular season as well, making him a viable option at his salaries.

Jordan Poole - PG/SG, GSW at DEN ($8,100 DK; $7,200 FD)

Stephen Curry is likely to continue coming off the bench for Game 3 given how well he's performed in that role to start the series, as it will allow his still recovering foot to get more down time. That would equate to another first-unit role for Poole, who scored 54.8 DK/54 FD points in Game 2 and has shot 65.5 percent, including 58.8 percent from behind the arc, over the first two games of the series. The elite shooting performances are par for the course for Poole against Denver, a team he's now drained 61.1 percent of his attempts against, including 60.0 percent from distance, in five games since the start of the regular season.

ALSO CONSIDER: Stephen Curry, PG, GSW at DEN ($8,900 DK; $9,200 FD); Jalen Brunson - PG, DAL at UTA ($8,000 DK; $8,000 FD)

 

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DraftKings and FanDuel Forwards - NBA DFS Lineup Picks

Anthony Edwards - PF, MIN at MEM ($8,200 DK, $8,800 FD)

Edwards eclipsed 50 fantasy points against the Grizzlies in a spectacular Game 1 upset before coming back a bit down to earth in Game 2 with 30.5 DK/26.7 FD points. However, his salaries remain reasonable for his upside, and he's shooting 41.5 percent from three-point range in six games against the Grizzlies since the start of the regular season. Even though Edwards has actually been a better performer on the road than at home this season, his heavy workload and the fact Game 3 could well turn out a wire-to-wire affair should give him a very strong chance of delivering on his salaries.

Draymond Green - PF, GSW at DEN ($6,700 DK; $6,700 FD)

Green has gotten the series off to a strong start, averaging 32.1 DK/34.2 FD points in his first two games. The versatile veteran is contributing clear across the stat sheet as usual, and there's always a chance for at least an uptick in offensive involvement whenever Stephen Curry isn't on the first unit, as is likely to be the case again Thursday. The Nuggets are ranked in the bottom half of the league with over 48 fantasy points per game given up on either site to power forwards in the last seven as well, and Green was a very efficient shooter on the road this season, draining 52.5 percent of his attempts, including an outstanding 40.0 percent from three-point range.

Bojan Bogdanovic - SF, UTA at DAL ($6,000 DK; $6,200 FD)

Bogdanovic has had the hot hand over the first two games of the series, especially relevant for a streaky shooter such as himself. The veteran wing is averaging 25.5 points on 57.1 percent shooting, leading to totals of over 30 DK points in both games and an average of 34 FD points. Those are very good returns on his current salaries, and considering he's now shooting 57.3 percent overall against the Mavs in five games since the start of the regular season, including 38.2 percent from three-point range, he's an excellent cost-savings option again for Game 3.

ALSO CONSIDER: Andrew Wiggins, GSW at DEN ($5,900 DK; $5,900 FD)

 

DraftKings and FanDuel Centers - NBA DFS Lineup Picks

Nikola Jokic -  DEN vs. GSW ($11,200 DK; $11,400 FD)

Jokic was once again the Nuggets' top player in the Game 2 loss, eclipsing 50 fantasy points on either site. However, that's actually a downturn for Jokic when compared to the extremely lofty standards he's set for himself, such as when he rattled off seven straight games with more than 70 fantasy points at the end of the regular season. The Warriors do have excellent numbers against centers on paper, but on such a small slate, a player of Jokic's upside in a desperation postseason game and playing at home, where he averaged over 60 fantasy points on each site this season, is one that has to be considered.

Rudy Gobert, UTA vs. DAL ($7,600 DK; $7,700 FD)

Gobert offers some nice savings if you're pivoting off Jokic, as he provides a steady albeit less spectacular floor than his fellow big man. The Stifle Towner has opened the series scoring over 30 fantasy points on either site in each game thus far, and he's averaging over 35 fantasy points per game versus Dallas overall in five games against Dallas since the start of the regular season. It's also worth noting Utah limited opponents to 44.4 percent shooting on its home floor, where Gobert averaged over 40 fantasy points per game, during the regular season, which should certainly help the big man's rebounding prospects.

ALSO CONSIDER: Karl-Anthony Towns, MIN at MEM ($9,300 DK; $9,700 FD)



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REAL-TIME FANTASY NEWS

Buddy Hield

Good to Go Wednesday
Jonathan Kuminga

Misses Fourth Consecutive Game
Alexandre Sarr

Unavailable on Wednesday
Draymond Green

Out Wednesday
Jimmy Butler III

Misses Meeting With Heat
Conor Garland

to Return on Thursday
Thomas Harley

to Miss Road Trip
Eetu Luostarinen

Out Week-to-Week After Barbecue Accident
Curtis Lazar

to Miss at Least Three Games
Al Horford

Ruled Out For Wednesday Against Miami
Vladimir Tarasenko

Misses Third Consecutive Game
Mikael Granlund

Remains Out Wednesday
Jaden McDaniels

Out Wednesday
Charlie McAvoy

Out Indefinitely After Facial Surgery
Joel Embiid

Unavailable Wednesday Against Raptors
Stephen Curry

Sidelined on Wednesday
Joe Burrow

to Potentially Return in Week 12?
Aaron Rodgers

Out on Wednesday, Hopes to Practice Thursday
Jaylen Warren

Not Seen at Wednesday's Practice
Dak Prescott

Lands on Injury Report Ahead of Week 12 With Hip Injury
Rhamondre Stevenson

Targeting a Return in Week 12?
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Returning to Practice on Wednesday
Brian Thomas Jr.

Jaguars "Optimistic" About Brian Thomas Jr.'s Week 12 Status
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Will Not Practice on Wednesday
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Looking to Continue Fall Run at RSM Classic
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Commanders Considering Shutting Down Jayden Daniels?
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Searching for Momentum at RSM Classic
Joel Dahmen

Trying to Find Form at the RSM Classic
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Ruled Out Again in Week 12
Drake London

Falcons Hoping That Drake London Will Return in Week 13
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Garrett Nussmeier Doubtful to Play Against Western Kentucky
Michael Penix Jr.

Needs Reconstructive Surgery on Torn ACL
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Expected to Return to Practice on Wednesday
Shedeur Sanders

Will Start Against Raiders
Dalton Kincaid

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Connor Bedard

Continues Tear With Hat Trick
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Pots Hat Trick in Tuesday's Win
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Records Eighth Career Hat Trick
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Alexander Romanov

Injured in Tuesday's Win
Ryan Hartman

Considered Week-to-Week
Michael Thorbjornsen

Hopes to End 2025 Campaign With Another Solid Finish
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Uncertain for Meeting With Nuggets
Sam Merrill

Iffy for Wednesday
Andrew Novak

Looks to End 2025 Season on High Note at RSM Classic
Dereck Lively II

Likely to Play Wednesday
Daniel Gafford

on Track to Return Wednesday
Jaden McDaniels

Uncertain for Wednesday
Jalen Smith

Expected to Play Wednesday
Tre Jones

Questionable for Wednesday
Coby White

Back in Bulls Lineup Wednesday
Harry Higgs

Teetering for PGA Tour Card in 2026
Kelly Oubre Jr.

Unavailable Wednesday
Darius Garland

Sits Out Wednesday's Game
PGA

Nico Echavarria has the Potential to Contend at the RSM Classic
Sam Stevens

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Seamus Power

Playing Better at the Right Time
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The Time is Now for Quade Cummins in Georgia
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Needs a Win at the RSM Classic
Cameron Champ

on the PGA Tour Card Bubble
Grayson Rodriguez

Shipped to Angels
Taylor Ward

Orioles Acquire Taylor Ward From Angels
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Accepts Cubs Qualifying Offer
Brandon Woodruff

Returning to Milwaukee in 2026
Denny McCarthy

Looking For Another Solid Finish at RSM Classic
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Looking To Use Current Momentum to Flip Script at RSM Classic
Zion Williamson

Considered Questionable for Wednesday
Bam Adebayo

Could Return to Action Wednesday
Mackenzie Hughes

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Harris English

Making 14th Start at This Week's RSM Classic
Konnor Griffin

Could Compete for Starting Shortstop Job in 2026
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Odell Beckham Jr.

Officially Reinstated by NFL Commissioner
Matt Murray

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Ilya Lyubushkin

Out on Tuesday
Jamie Benn

Makes Season Debut Tuesday
Evgenii Dadonov

on Track to Return Tuesday
Dougie Hamilton

a Game-Time Call Tuesday
Anthony Cirelli

Expected to Return Against Devils
Victor Hedman

Questionable for Tuesday
Auston Matthews

to Miss at Least Two More Games
C.J. Stroud

Expected to Return in Week 13 Against Colts
C.J. Stroud

to Miss Another Game
Joe Mixon

Uncertainty Remains Around Joe Mixon's Return Timeline
Jaylen Warren

Mike Tomlin Optimistic About Jaylen Warren's Availability for Week 12
C.J. Stroud

Not Expected to Play on Thursday Night
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Sam Leavitt Set to Enter Transfer Portal?
Jose Altuve

Undergoes Foot Surgery
Alex Bregman

Red Sox Going for Either Alex Bregman or Pete Alonso?
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James Franklin to be Virginia Tech's Next Head Coach
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Fernando Mendoza the Clear Heisman Trophy Favorite?
CFB

Beau Pribula Has Chance to Face Oklahoma on Saturday
Jack Della Maddalena

Gets Dominated
Islam Makhachev

Claims UFC Welterweight Belt
Zhang Weili

Gets Outclassed
Valentina Shevchenko

Wins Unanimous Decision At UFC 322
Sean Brady

Suffers First-Round TKO Loss
Michael Morales

Remains Unbeaten
Leon Edwards

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Leon Edwards

Carlos Prates Becomes The First Man To Knock Out Leon Edwards
Beneil Dariush

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Beneil Dariush

Benoit Saint Denis Knocks Out Beneil Dariush In 16 Seconds
Josh Naylor

Mariners Finalizing Five-Year Contract
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Jeremiah Smith, Carnell Tate Not Dealing With Long-Term Injuries
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Virginia Tech Close To Naming James Franklin As Head Coach
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Garrett Nussmeier Doubtful vs. Arkansas On Saturday
Edwin Díaz

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Jacob deGrom

Named AL Comeback Player of the Year
Ronald Acuña Jr.

Ronald Acuna Jr. Wins NL Comeback Player of the Year Award
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Edwin Díaz

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Wins his Fourth MVP Award
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