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DraftKings, FanDuel Daily Fantasy Basketball Picks (4/21/22): Today's Top NBA DFS Lineups

The top daily fantasy basketball lineup picks for DraftKings and FanDuel on April 21, 2022. Juan Carlos Blanco provides NBA DFS analysis and sleeper picks for building optimal DFS rosters.

We're primed for yet another three-game playoff slate tonight and another solid NBA DFS slate. We have three game threes on the docket tonight!

The Memphis-Minnesota series is knotted 1-1 heading into game three as is the Utah-Dallas series. Meanwhile, the Nuggets are fighting for their playoffs lives as they come home down 0-2 to the Warriors in game three of their series.

This article will provide you with my daily fantasy basketball lineup picks for DraftKings and FanDuel on 4/21/22. Remember to monitor the NBA injury report as the slate can completely change before lineup lock, which is at 7:30 pm ET tonight. Good luck, RotoBallers.

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DraftKings and FanDuel Guards - NBA DFS Lineup Picks

Ja Morant - PG, MEM vs. MIN ($9,800 DK; $9,900 FD)    

Morant looked all the way back from his recent knee injury in Game 2, shooting 56.3 percent on his way to a 23-point, 10-assist double-double that also included nine rebounds. The star guard is still shooting 38.9 percent overall against Minnesota in six meetings since the start of the regular season, but he's now eclipsed 50 DK points in each of the first two games of the series. The T-Wolves were an excellent defense at home this regular season, but there's naturally no double Morant will once again have a massive role and there's also a good chance Thursday's game comes right down to the buzzer after the double-digit margins of victory for each team in the first two games.

Donovan Mitchell - PG/SG, UTA vs. DAL ($8,400 DK; $9,000 FD)

Mitchell has overcome some shooting inefficiency with significant volume in the first two games of the series, as he's racked up 32 and 34 points while putting up a whopping 59 attempts. That's led to a pair of tallies over 40 fantasy points on each site, and the heavy involvement should naturally persist on Utah's home floor of Vivint Arena on Thursday. Mitchell was a slightly better shooter at home this season, posting a 44.8 percent success rate from the floor, including 36.0 percent from three-point range. He's averaging over 40 fantasy points on each site against the Mavs in six meetings since the start of the regular season as well, making him a viable option at his salaries.

Jordan Poole - PG/SG, GSW at DEN ($8,100 DK; $7,200 FD)

Stephen Curry is likely to continue coming off the bench for Game 3 given how well he's performed in that role to start the series, as it will allow his still recovering foot to get more down time. That would equate to another first-unit role for Poole, who scored 54.8 DK/54 FD points in Game 2 and has shot 65.5 percent, including 58.8 percent from behind the arc, over the first two games of the series. The elite shooting performances are par for the course for Poole against Denver, a team he's now drained 61.1 percent of his attempts against, including 60.0 percent from distance, in five games since the start of the regular season.

ALSO CONSIDER: Stephen Curry, PG, GSW at DEN ($8,900 DK; $9,200 FD); Jalen Brunson - PG, DAL at UTA ($8,000 DK; $8,000 FD)

 

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DraftKings and FanDuel Forwards - NBA DFS Lineup Picks

Anthony Edwards - PF, MIN at MEM ($8,200 DK, $8,800 FD)

Edwards eclipsed 50 fantasy points against the Grizzlies in a spectacular Game 1 upset before coming back a bit down to earth in Game 2 with 30.5 DK/26.7 FD points. However, his salaries remain reasonable for his upside, and he's shooting 41.5 percent from three-point range in six games against the Grizzlies since the start of the regular season. Even though Edwards has actually been a better performer on the road than at home this season, his heavy workload and the fact Game 3 could well turn out a wire-to-wire affair should give him a very strong chance of delivering on his salaries.

Draymond Green - PF, GSW at DEN ($6,700 DK; $6,700 FD)

Green has gotten the series off to a strong start, averaging 32.1 DK/34.2 FD points in his first two games. The versatile veteran is contributing clear across the stat sheet as usual, and there's always a chance for at least an uptick in offensive involvement whenever Stephen Curry isn't on the first unit, as is likely to be the case again Thursday. The Nuggets are ranked in the bottom half of the league with over 48 fantasy points per game given up on either site to power forwards in the last seven as well, and Green was a very efficient shooter on the road this season, draining 52.5 percent of his attempts, including an outstanding 40.0 percent from three-point range.

Bojan Bogdanovic - SF, UTA at DAL ($6,000 DK; $6,200 FD)

Bogdanovic has had the hot hand over the first two games of the series, especially relevant for a streaky shooter such as himself. The veteran wing is averaging 25.5 points on 57.1 percent shooting, leading to totals of over 30 DK points in both games and an average of 34 FD points. Those are very good returns on his current salaries, and considering he's now shooting 57.3 percent overall against the Mavs in five games since the start of the regular season, including 38.2 percent from three-point range, he's an excellent cost-savings option again for Game 3.

ALSO CONSIDER: Andrew Wiggins, GSW at DEN ($5,900 DK; $5,900 FD)

 

DraftKings and FanDuel Centers - NBA DFS Lineup Picks

Nikola Jokic -  DEN vs. GSW ($11,200 DK; $11,400 FD)

Jokic was once again the Nuggets' top player in the Game 2 loss, eclipsing 50 fantasy points on either site. However, that's actually a downturn for Jokic when compared to the extremely lofty standards he's set for himself, such as when he rattled off seven straight games with more than 70 fantasy points at the end of the regular season. The Warriors do have excellent numbers against centers on paper, but on such a small slate, a player of Jokic's upside in a desperation postseason game and playing at home, where he averaged over 60 fantasy points on each site this season, is one that has to be considered.

Rudy Gobert, UTA vs. DAL ($7,600 DK; $7,700 FD)

Gobert offers some nice savings if you're pivoting off Jokic, as he provides a steady albeit less spectacular floor than his fellow big man. The Stifle Towner has opened the series scoring over 30 fantasy points on either site in each game thus far, and he's averaging over 35 fantasy points per game versus Dallas overall in five games against Dallas since the start of the regular season. It's also worth noting Utah limited opponents to 44.4 percent shooting on its home floor, where Gobert averaged over 40 fantasy points per game, during the regular season, which should certainly help the big man's rebounding prospects.

ALSO CONSIDER: Karl-Anthony Towns, MIN at MEM ($9,300 DK; $9,700 FD)



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REAL-TIME FANTASY NEWS

NFL

Jordyn Tyson to Hold Individual Workout on April 17
Brent Rooker

Exits Early on Thursday Due to Apparent Injury
NFL

No New Injury Issues for Francis Mauigoa
Travis Hunter

to be "Limited Participant" During Offseason Workouts
Carolina Panthers

Denzel Boston Visiting With Panthers on Thursday
Mark Andrews

Ready for More Opportunities in 2026
Tyrone Tracy Jr.

Part of a Muddled Giants Backfield Heading into 2026
Chimere Dike

Fantasy Value Potentially Limited by What He Offers in Return Game
Chase Brown

an Important Name to Monitor on Day 1 of the NFL Draft
Bijan Robinson

Could Just Be Entering His Prime
Jameson Williams

Consistency the Key to a True Jameson Williams Breakout
Jarace Walker

May Exit Pacers Lineup Again Thursday
Aaron Nesmith

Out for Sixth Consecutive Game
T.J. McConnell

Andrew Nembhard, T.J. McConnell Unavailable Thursday
Dru Smith

Iffy for Thursday
Norman Powell

Questionable Thursday
Sam Hauser

Could Miss Thursday's Game
Neemias Queta

Uncertain for Thursday
Zach Benson

Scores Twice in Comeback Victory
Logan Thompson

Shuts Out the Leafs
Zach Eflin

Undergoes Successful Elbow Surgery, Will Miss Remainder of 2026
Derrick White

Listed as Questionable for Thursday
Tre Johnson

Iffy for Thursday
Jaylen Brown

Iffy to Face Knicks
Bilal Coulibaly

Questionable Against Bulls
Gui Santos

Could Miss Another Game Thursday
Alexandre Sarr

Out Again Thursday
Al Horford

to Remain Out Thursday
Caleb Martin

Remains Sidelined Wednesday
Kristaps Porzingis

Unavailable Against Lakers
Klay Thompson

Ruled Out Wednesday
Stephen Curry

Questionable for Thursday Night
Brandon Williams

to Miss Back-To-Back with Illness
LeBron James

Ready to Return Thursday
Daniel Gafford

Ruled Out Vs. Phoenix
J.K. Dobbins

Broncos Prioritized Re-Signing J.K. Dobbins
NFL

Francis Mauigoa to Undergo Additional Imaging on a Back Issue
Kaleb McGary

Retires After Seven Years in the NFL
Jawaan Taylor

Signs with the Falcons
Andrei Kuzmenko

to Be Re-Evaluated in 7-8 Days
Mason Appleton

Won't Play Thursday
Tony DeAngelo

Expected to Return Thursday
John Klingberg

Rejoins Sharks Lineup Wednesday
Alex Lyon

Dealing With Lower-Body Injury
Oliver Ekman-Larsson

Back in Action Wednesday
Alex Ovechkin

Won't Decide Future Until Offseason
Cole Ragans

"Should be Good" for Next Start
Reynaldo López

Reynaldo Lopez Handed Seven-Game Suspension
Jorge Soler

Suspended Seven Games, Will Appeal
NFL

NFL Scouts See Plenty of Upside With Drew Allar
NFL

Ty Simpson to Fall into Second Round in NFL Draft?
Cleveland Browns

Todd Monken "Fired Up" About Quarterback Competition
Cleveland Browns

KC Concepcion Visiting With the Browns
Cole Ragans

Diagnosed With Thumb Contusion
Houston Texans

Texans Pick Up Will Anderson's Fifth-Year Option
C.J. Stroud

Texans Exercise C.J. Stroud's Fifth-Year Option
Cole Ragans

Leaves Early on Wednesday After Being Hit in the Hand
Jacob deGrom

Expects to Make his Next Start
Konnor Griffin

Pirates Sign Konnor Griffin to Nine-Year Extension
Parker Washington

Undervalued Despite League-Winning Finish in 2025
Justus Annunen

Ends Predators' 120-Game Streak Without a Shutout
Trevor Zegras

Leads Flyers to Victory Tuesday
Kevin Bahl

Sustains Lower-Body Injury Against Stars
Michael Rasmussen

Likely to Miss Rest of Regular Season
Dmitry Kulikov

Done for the Season After Breaking Finger
Jalen Chatfield

Exits Early With Lower-Body Injury
Nazem Kadri

Suffers Upper-Body Injury Tuesday
Tyrrell Hatton

a Steady Option at The Masters
Justin Thomas

a High-Risk, High-Reward Option at The Masters
PGA

Sungjae Im a Volatile Option at the Masters
Nicolai Hojgaard

Carrying Momentum Into The Masters
Si Woo Kim

in Strong Form Heading to The Masters
Chris Gotterup

Ready to Make His Masters Debut
Patrick Reed

Brings Momentum to The Masters
Jon Rahm

Looks Poised for His Second Green Jacket
Morgan Geekie

Collects Second Career Hat Trick
Joel Eriksson Ek

has Three Points in Victory
Jacob deGrom

Doesn't Have Structural Damage in his Knee
J.T. Realmuto

Leaves Game on Tuesday Due to Bruised Right Foot
Cody Ponce

to Have Knee Surgery, Expected to Miss Six Months
Alejandro Kirk

Facing Six-Week Absence
Jacob deGrom

to Undergo MRI on Tuesday
Mike Trout

Back in the Lineup on Tuesday
Hunter Brown

Diagnosed with Grade 2 Shoulder Strain
Pavel Mintyukov

Returns From Three-Game Absence
Cutter Gauthier

Remains Sidelined Tuesday
Kirby Dach

Ready to Return Tuesday
Adam Scott

Form Points to Him Competing at Masters
Jordan Spieth

Finding Consistency Heading to Masters
Hideki Matsuyama

Trending In Right Direction For Masters
Cade Horton

to Undergo Season-Ending Elbow Surgery
Tommy Fleetwood

a Contender if his Putter Cooperates at The Masters
Jacob deGrom

Pitches Through Knee Issue on Monday
Dalton Rushing

Smacks Two Homers in Rout of Blue Jays
Max Scherzer

Dealing With Forearm Tendinitis, Expected to Make his Next Start
Collin Morikawa

Vegas has Lost Confidence in Collin Morikawa Ahead of Masters Tournament
Ludvig Aberg

One of the Top Plays For This Week's Masters Tournament
Rory McIlroy

Set to Defend his Long-Awaited Masters Victory
Bryson DeChambeau

Looks to Finally Claim a Green Jacket
Patrick Cantlay

Needs Plenty to Go Right at Augusta
Harris English

Playing Solid Golf Heading to Masters
Sam Burns

Bouncing Back Nicely After Slow Start to 2026 Season
Corey Conners

Quietly Putting Together A Strong 2026 Season
Russell Henley

Looks to Bounce Back At Masters
Mike Trout

Held Out of Series Opener Against Braves
Chris Duncan

Suffers Second-Round Submission Loss
Renato Moicano

Gets Back In The Win Column
Tabatha Ricci

Gets Outgrappled
Virna Jandiroba

Bounces Back
Brendson Ribeiro

Suffers First-Round Submission Loss
Abdul-Rakhman Yakhyaev

Earns First-Round Submission Win
Rafael Estevam

Suffers His First Loss
Ethyn Ewing

Dominates At UFC Vegas 115
RANKINGS
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SS
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SP
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