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Mike Marteny's DraftKings daily fantasy college football lineup picks for the Saturday (11/15/25) evening slate in Week 12. His CFB DFS lineup picks and DFS sleepers will help you win.
We have a big evening slate with eight games on tap. We start in Sin City with Utah State visiting UNLV. Florida heads to Mississippi to interview Lane Kiffin at halftime. Utah is in Waco to take on Baylor. Purdue is in Madison to take on Wisconsin.
Next up is the marquee game with Texas between the hedges in Athens. Virginia Tech heads to Tallahassee to take on Florida State. UCLA is at the Shoe to take on Ohio State. We end this in Columbia with Missouri hosting Mississippi State.
In this article, I will provide you with my daily fantasy college football lineup picks for the evening DraftKings slate on 11/15/25, starting at 7 pm Eastern. I’ll give multiple player suggestions for quarterbacks, running backs, and wide receivers, aiming to highlight one option at each end of the salary scale, from the highest to the lowest. Good luck, RotoBallers.
Be sure to check all of our fantasy football rankings for 2025:- 2025 fantasy football rankings
- Running back (RB) fantasy football rankings
- Wide receiver (WR) fantasy football rankings
- Tight end (TE) fantasy football rankings
- Quarterback (QB) fantasy football rankings
- FLEX fantasy football rankings
- Defense (D/ST) fantasy football rankings
- Kicker (K) fantasy football rankings
- Dynasty fantasy football rankings
DraftKings CFB DFS Picks - Quarterbacks
Julian Sayin, Ohio State ($8.8K)
Part of me thinks that Ohio State is going to try to establish the run in this one. Another part of me thinks the Buckeyes will keep the Sayin for Heisman narrative alive. To do that, Sayin will have to throw for over 300 yards for the fourth straight game.
Sayin's ceiling isn't all that high, leaving him more of a cash game play. However, the floor is relatively high, making Sayin a solid addition to smaller tournaments and single-entry plays.
Anthony Colandrea, UNLV ($7.7K)
It’s ALLLLL Rebels on the road 🤠
Anthony Colandrea’s wild fake-out at the goal line has UNLV on top of Colorado State 35-10 after 3 quarters. pic.twitter.com/SoNmJxIaw3
— Nick Walters (@nickwalt) November 9, 2025
UNLV's defense has ruined what could have been a special season for the team, but it hasn't stopped the Colandrea train. The Virginia transfer has at least 30 DraftKings points in four straight games.
Utah State's defense allows 421.6 yards per game, 181.6 of those on the ground. Colandrea's ceiling is the highest on the slate thanks to his rushing ability. He has five rushing touchdowns in the last four games to go with eight passing touchdowns. He'll have his way with the Aggies here.
Kyron Drones, Virginia Tech ($6.6K)
The Hokies were so bad that their coach was the first to be fired this year. It feels like years ago already. Drones has been more of his old self lately. His efficiency as a passer leaves something to be desired, but he has at least 80 rushing yards in three straight games.
He also has six touchdowns through the air in that span. We don't care about efficiency. We care about results, and the results are there. Drones could be a great bargain at this price.
Also consider these QBs:
- Demond Williams Jr., Washington ($9.1K)
- Gunner Stockton, Georgia ($8.1K)
- Bryson Barnes, Utah State ($7.6K)
- Sawyer Robertson, Baylor ($7.1K)
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DraftKings CFB DFS Picks - Running Backs
Kewan Lacy, Mississippi ($7.7K)
The Kewan Lacy show 👀#HottyToddy pic.twitter.com/sc1J5iyRMq
— Ole Miss Football (@OleMissFB) November 8, 2025
Lacy leads FBS with 16 rushing touchdowns and is one shy of the school record set by Quinshon Judkins before he left for Columbus. His 916 rushing yards lead the SEC. Lacy has eight touchdowns in the last four games alone.
The Florida defense has struggled to stop the run this year. We could see another big game out of Lacy. His season low in DraftKings points is 18.4. Name another player at any price and any position that has that good of a floor.
Bo Jackson, Ohio State ($6.5K)
Could you imagine if we had DFS around when the original Bo Jackson played? We'll have to settle for this Bo Jackson. Jackson has double-digit touches in all but the first two games of the season before he really got into the rotation.
The touchdown total leaves something to be desired, but UCLA has allowed a miserable 191.1 rushing yards per game this year. That's 123rd in FBS. Jackson should be a lock for a lot of yards if nothing else.
Miles Davis, Utah State ($5.9K)
UNLV has allowed 185.2 rushing yards per game this year. That's 120th out of 136 FBS teams. Barnes doesn't get the workload of some other backs, but he sees around 15 touches a game. 15 touches against this defense at this price could net us a lot of points!
Also consider these RBs:
- Ahmad Hardy, Missouri ($7.5K)
- Jai'Den Thomas, UNLV ($7.1K) - if active. If he's out, use Keyvone Lee.
- Nate Frazier, Georgia ($6.3K)
- Javen Jacobs, Utah State ($4.3K)
DraftKings CFB DFS Picks - Wide Receivers
Jeremiah Smith, Ohio State ($8.7K)
Smith is expensive, but we can't pretend like he hasn't been worth it. Smith has 16 receptions for 260 yards and three scores in the last two games alone. This UCLA defense is worse than Penn State's and on par with Purdue's.
The only thing that we have to worry about is Ohio State calling off the dogs. Both of the last two games were convincing wins, so we'll likely see a good day out of Smith before he's done.
Duce Robinson, Florida State ($6K)
Robinson was the alpha receiver to begin the season, but FSU wen't away from him in a couple of losses. He's back at the top, with 53.2 DK points in the last two games alone. He has 14 receptions for 272 yards and a score. We'll see another big game out of Duce tonight.
Brenen Thompson, Mississippi State ($5.3K)
Thompson is one of the fastest receivers in college. He has double-digit DK points in all but the Tennessee game. He's a threat to take it in from anywhere on the field. Thompson has at least four receptions in each of the last four games, giving him more of a chance to make an impact.
Emmett Mosley V, Texas ($4.4K)
The Stanford transfer missed the first half of the season, and it took him a couple of games to get on the same page as Arch Manning. The two are in sync now. Mosley has 11 receptions for 122 yards and three touchdowns in the last two games alone.
Expecting this against Georgia is a little ambitious, but the price is right for the targets Mosley will get. If Georgia can't get after Arch, we could see another big game out of Mosley.
Troy Omeire, UNLV ($3.3K)
Omeire is still too cheap. He only has one game under 5 DK points this year, and has double figures in four of his seven games. He's kind of an all-or-nothing play, but he rarely gets nothing.
Also consider these WRs:
- Denzel Boston, Washington ($7.8K)
- Ryan Wingo, Texas ($6.2K)
- Braden Pegan, Utah State ($5.9K)
- Jaden Bradley, UNLV ($5.7K)
- Zachariah Branch, Georgia ($5.2K)
- DaeDae Reynolds, UNLV ($4.2K)
- Takye Heath, Virginia Tech ($3.4K)
DraftKings CFB Stacks
Utah State vs. UNLV - Game Stack
Both defenses are terrible. Utah State allows 421.6 yards and 29.8 points per game. UNLV allows 450.2 yards and 31.6 points per game. Now you see why I like the over 70 in this game!
The good news is that Colandrea and Barnes are both affordable. If Jet Thomas is out, Keyvone Lee gives us yet another salary saver. We can then stack these two teams and still afford Jeremiah Smith.
Utah State is more of a run team than a passing team, so if you run a full five-man Utah State stack, it should start with Barnes, Miles Davis, and Javen Jacobs. Pegan and Brady Boyd are the receivers to use.
UNLV is a bit harder to full stack without the status of Thomas. Colandrea, Thomas, Bradley, Omeire, and DaeDae Reynolds are my preferred stack if Thomas can go. If he can't, Keyvone Lee is a must-play.
Mississippi vs. Florida
If Florida has indeed checked out, there are points to be had with the Mississippi offense. Trinidad Chambliss is as dangerous as they come. Lacy is a must-play in any lineup. Harrison Wallace III, Dae'Quan Wright, and De'Zhaun Stribling would complete the stack.
Even though this Mississippi stack has a good ceiling, they are likely a stack option or Lacy alone for me. There are other options for the price that could be better plays if you don't care about the correlation.
Also consider these stacks:
- Ohio State
- Utah (GPP only)
- Florida State (GPP only)
