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Saturday Football Matchups Analysis - Week 16

Saturday football starts/sits and matchups analysis for Week 16 of the NFL season. Which fantasy football players start or sit for fantasy football lineups.

I hope everyone is enjoying a restful holiday season! Although Thursday Night Football has concluded for the 2019 NFL season, there are still a bevy of games to be played on Saturday in Week 16 that will determine the fates of fantasy owners who have made it thus far without being eliminated from the playoffs.

Fortunately, RotoBaller has you covered ahead of the Saturday triple-header to provide lineup advice that could make or break your championship run.

Let's dive in to some matchup analysis for the trio of Saturday football games in Week 16! You can read the Sunday game breakdowns as well by Chris O'Reilly and Pierre Camus.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Houston Texans @ Tampa Bay Buccaneers

Date and Start Time: Saturday, December 21 at 1:00 PM ET

Notable Injuries and Status:

Offensive and Defensive Rankings:

Texans Buccaneers
Passing Yards 11th 1st
Rushing Yards 7th 27th
Pass Defense 28th 30th
Rush Defense 19th 1st

 

Buffalo Bills @ New England Patriots

Date and Start Time: Saturday, December 21 at 4:30 PM ET

Notable Injuries and Status:

Offensive and Defensive Rankings:

Bills Patriots
Passing Yards 28th 9th
Rushing Yards 5th 19th
Pass Defense 3rd 2nd
Rush Defense 10th 7th

 

Los Angeles Rams @ San Francisco 49ers

Date and Start Time: Saturday, December 21 at 8:15 PM ET

Notable Injuries and Status:

Offensive and Defensive Rankings:

Rams 49ers
Passing Yards 6th 13th
Rushing Yards 24th 2nd
Pass Defense 9th 1st
Rush Defense 23rd 21st

 

Must Starts

Top Performers That Have To Be In Your Lineups

Deshaun Watson (QB, HOU)

Watson will poke holes in the Buccaneers horrid passing defense like it is Swiss cheese. Start him with confidence as a top-three option at the quarterback spot.

DeAndre Hopkins (WR, HOU)

Similar to the man throwing him the football, Hopkins will undoubtedly prosper against a Tampa defense with no ability to shut down opposing wideouts and he should remain a fixture in fantasy lineups.

Cooper Kupp (WR, LAR)

Odds are good that Kupp will either finish Week 16 with his exceptionally high floor of receptions, a score, or both. While one of his dud games did come against San Francisco back in Week 6, no fantasy owners is considering sitting Kupp in (preemptively) their championship game.

George Kittle (TE, SF)

We know by this point how much of a fantasy stud Kittle is. In case you forgot, Kittle accounted for 67 percent of the 49ers' receiving yardage last week on a ridiculous 17 targets and should see heavy volume when the team faces off against an NFC West rival.

 

Solid Options/Sleepers

Which Players Will Have Solid Games and Which Could Surprise?

Solid Option: Jameis Winston (QB, TB)

Despite Tampa's receiving core being absolutely decimated by injuries, the matchup is too good to not put Winston as a strong start this week. The former Seminole has only thrown for less than 300 passing yards and a score once since the Buccaneers Week 7 bye and Houston is a high-powered offense ready to battle in a shootout game-script.

Solid Option: Devin Singletary (RB, BUF)

Fantasy owners are chasing the volume when they consider starting Singletary, as he has had snap rates of at least 70 percent over his last three games. He deserves RB2 consideration despite facing a stout New England front seven.

Solid Option: Todd Gurley (RB, LAR)

Gurley has been on fire as of late with head coach Sean McVay seeming to find more creative ways to use him on the field. The 2015 NFL Draft's tenth overall pick will get the lion's share of Los Angeles' carries and should add on to his three game touchdown streak.

Solid Option: Raheem Mostert (RB, SF)

The 49ers have treated Mostert as his if he has earned the starting running back gig for San Francisco, handing him the ball no less than ten times in his last three games. With some certainty about who will get the bulk of the team's rush attempts, Mostert is a valuable fantasy asset.

Solid Option: Breshad Perriman (WR, TB)

No Mike Evans, no Chris Godwin, no problem. Perriman has stepped up big time for a Buccaneers offense that desperately needs a playmaker, exploding to the tune of five receptions for 113 yards and three scores in a Week 15 tilt with the Detroit Lions.

Solid Option: Julian Edelman (WR, NE)

Fantasy owners will need to keep a close eye on whether Edelman actually plays this week or New England opts to rest him ahead of a playoff run. If he is active, Edelman will continue to be a PPR scoring machine with the absurd number of targets he is averaging this season.

Solid Option: Robert Woods (WR, LAR)

Woods' ability to produce will hinge on whether 49ers defensive back Richard Sherman has fully recovered from a hamstring injury that kept him sidelined in Week 15. If Sherman is stymied, fantasy owners can consider Woods a flex option with upside.

Sleeper: Will Fuller (WR, HOU)

The prototypical boom or bust play in fantasy football, Fuller has a greater likelihood of fulfilling the boom side of the equation against a Buccaneers secondary that gives up the most fantasy points to opposing wide receivers.

Sleeper: Emmanuel Sanders (WR, SF)

So long as he can avoid coverage from defensive back Jalen Ramsey, Sanders should bounce back from a paltry two reception, nine yard effort in the upset loss versus Atlanta last week. Although his upside isn't anything more than a WR2, consider him a flex option if you don't have better options available.

Sleeper: O.J. Howard (TE, TB)

The absence of capable pass catchers in Tampa's receiving core due to injuries has opened up the door for Howard to make an impact, but his usage to date hasn't exactly inspired much confidence in the third-year pro.

 

Consider Sitting

Players To Avoid Putting In Your Lineup If Possible

Josh Allen (QB, BUF)

Allen has been a matchup play for fantasy owners who can exploit vulnerable defenses, but New England is the squad that can force him to throw for under 200 yards and plenty of turnovers (such as three interceptions back in Week 4).

Tom Brady (QB, NE)

I didn't expect the day when I would put Brady on the "Consider Sitting" list to come this season, but it's impossible to ignore the lack of productivity that has come from New England's signal-caller over the last few weeks. Buffalo is an especially hard draw to project Brady as anything more than a QB2 ahead of Saturday.

Jared Goff (QB, LAR)

The regression is noticeable in Goff, who simply hasn't looked sharp in making on point throws in tight windows. San Francisco is such a crew that will keep throwing lanes tight and pose trouble for Goff returning fantasy points for his owners.

Jimmy Garoppolo (QB, SF)

While we have seen flashes from Garoppolo, the more likely game plan for the 49ers offense will be to hand the football off to their most capable rusher and churn out yardage on the ground. Garoppolo will be a game-script dependent option in Week 16.

Carlos Hyde/Duke Johnson (RBs, HOU)

What Tampa's defense lacks in ability to stop the pass it more than makes up for in stymieing opposing running backs. Neither Hyde or Johnson have any safe floor in this matchup and should be avoided at all costs.

Ronald Jones/Peyton Barber (RBs, TB)

The Buccaneers running back who will finish with the better fantasy day by the time the conclusion of Week 16 comes around is largely unclear, but neither inspire much hope as fantasy options even with head coach Bruce Arians saying he intends to involve his backs in the team's passing attack against Houston.

Frank Gore (RB, BUF)

The Bills backfield is Devin Singletary's to lose, making Gore largely an afterthought barring the team accumulating a hefty lead.

Patriots Running Backs (RBs, NE)

New England's offense no longer carries the label of being high-powered, removing the scoring upside from any of their running backs that was by and large the most attractive feature of that group in fantasy football.

Tevin Coleman/Matt Breida (RBs, SF)

Coleman and Breida have been receiving change of pace work since Raheem Mostert has proven to head coach Kyle Shanahan that he deserves to be the top dog in the 49ers backfield. Breida may carry more value than Coleman at this point, but that isn't saying much.

Phillip Dorsett / Mohamed Sanu / N'Keal Harry (WRs, NE)

The recent struggles of quarterback Tom Brady have left his receiving core out to dry when it comes to their fantasy production. The potential absence of Julian Edelman could lead to a resurgence, but which wideout will contribute enough to be a flex option is a dart throw.

Kenny Stills (WR, HOU)

Since being described as one of the hottest waiver pickups in the wake of Will Fuller getting injured, Stills has largely been a disappointment, especially recently with a combined 11 targets in his last four games.

John Brown/Cole Beasley (WRs, BUF)

Either Brown or Beasley could receive a healthy share of looks against a tough divisional rival Patriots secondary. The question of how productive said looks will be is a whole other matter and likely to lead to disappointment for those fantasy owners who start them.

Darren Fells (TE, HOU)

Although Tampa Bay is a juicy matchup for fantasy tight ends, the split in receiving usage between Jordan Akins and Fells has contributed to the latter largely falling off the face of the earth for fantasy purposes.

Cameron Brate (TE, TB)

Much like his tight end teammate O.J. Howard, Brate could be looked at to fill the void left by injuries to Tampa's pass catchers. Nonetheless, he will be a touchdown-dependent option that should be benched in favor of better options.

Gerald Everett / Tyler Higbee (TEs, LAR)

The 49ers Defense gives up the third-fewest fantasy points to tight ends and Everett's return from injury creates an unpredictable situation for determining which tight end will get the most looks. Either could be started in a pinch, but only as a TE2 play.

More Lineup Prep




REAL-TIME FANTASY NEWS

NBA

Bulls Host Potential Lottery Picks for Workout
NBA

Wizards Considering Trading Down in Draft
Russell Wilson

Retiring From the NFL
Corbin Burnes

has Teres Major Strain, Unlikely to Return Until September
Malik Davis

Appears to be the Front-Runner for RB2 Job in Dallas
Kayshon Boutte

to Compete for Snaps in Three-Receiver Sets
Alvin Kamara

Attends OTAs on Wednesday
Andrei Iosivas

Is it Time for Dynasty Managers to Drop Andrei Iosivas?
Tyjae Spears

Is Tyjae Spears Droppable in Dynasty Formats?
Jaylen Wright

the Dynasty Handcuff Running Back to Own in Miami?
Colby Parkinson

Facing Likely Regression After Career Year in 2025
Omarion Hampton

Remains a High-End Dynasty RB1 Despite Injury History
Rickie Fowler

Looks To Continue Resurgent Season At Memorial
Ollie Gordon II

Is Ollie Gordon II Still Worthy of a Dynasty Roster Spot?
Justin Herbert

Overhauling his Footwork This Offseason
De'Von Achane

Doing Individual Drills at Minicamp
Ashton Jeanty

Raiders Emphasizing Ashton Jeanty's Progress as Their Lead Back
Marvin Harrison Jr.

Still on the Mend From 2025 Injuries
Brandon Aiyuk

Warrant Issued for Brandon Aiyuk's Arrest in California
Blake Corum

Remains an Elite Handcuff in Dynasty Leagues
Chris Godwin Jr.

Consistency the Key for Chris Godwin Jr. in Dynasty Leagues
David Montgomery

Can Managers Look to Sell High on David Montgomery This Year?
Malik Willis

a Low-Cost Dynasty Target in Miami?
Terrance Ferguson

Can Terrance Ferguson Still be the Tight End to Roster in Los Angeles?
CFB

Can Eric Singleton Jr. Fully Break Out at Third School?
CFB

Katin Houser Steps into QB1 Role for Illinois
CFB

Savion Hiter an Immediate Impact Freshman for Michigan
CFB

Isaiah Horton Set to Take Over KC Concepcion's Role
CFB

UCLA Transfer Karson Gordon Signs with Austin Peay
CFB

Will Muschamp Bringing New Intensity to Texas Practices
Gary Woodland

Brings Boom-or-Bust Potential to Memorial
Jordan Spieth

Still Searching for a Breakthrough
Ted Hurst

Can Ted Hurst Find Consistent Fantasy Success in a Crowded Receiver Room?
Alex Smalley

Brings Elite Form to Memorial Tournament
Justin Rose

Looks to Recapture Memorial Tournament Success
Cameron Young

Looks to Get Back to His Contending Ways at Murifield Village
Chris Gotterup

Needs to Find Fairways at Muirfield Village
Si Woo Kim

Looks to Stay Hot at Memorial Tournament
Matt Fitzpatrick

Positioned for Success at Muirfield Village
Jalen Chatfield

Records Two Assists in Tuesday's Loss
Keegan Bradley

Looking for Another Strong Finish at Muirfield
Nikolaj Ehlers

Nets Two Goals in Game 1 Loss to Golden Knights
Shea Theodore

Notches Three Points in Game 1 Win
Brayden McNabb

Sets Up Three Goals in Game 1 Win Over Hurricanes
Justin Thomas

is an Exciting Play This Week in Ohio
Brett Howden

Starts Finals With Multi-Point Effort
Scottie Scheffler

Looks to Win Memorial Tournament for Third Consecutive Year
Tomas Hertl

Scores Game-Winner in Finals Opener
Rory McIlroy

Looking for Better Performance at Muirfield Village
Drake Baldwin

Could Return During Braves Next Homestand
Garrett Crochet

Diagnosed With Low-Grade Lat Strain
Russell Henley

Coming to Ohio on the Heels of Latest Victory
Tommy Fleetwood

Looking for Better Iron Play at Memorial Tournament
Patrick Cantlay

Looks to Continue Dominance at Muirfield Village
Ludvig Aberg

a Great Fit for Muirfield Village
Isaiah Hartenstein

Hopeful to Stay with Oklahoma City
Luguentz Dort

Wants to Remain with Thunder
Mitchell Robinson

is Questionable for Game 1
Moussa Diabaté

Moussa Diabate Has Contract Guaranteed for 2026-2027 Season
Oso Ighodaro

Gets Guaranteed Contract for Next Season
NAS

Chris MacFarland Joins Predators as President and General Manager
VAN

Canucks Name Manny Malhotra as New Head Coach
Brendan Gallagher

to Leave Canadiens This Offseason
Patrik Laine

Looking Forward to Free Agency
Jeremy Lauzon

Returns to Action Tuesday
Zach Werenski

Wins 2025-26 Norris Trophy
Aaron Judge

Out on Tuesday With Rib/Shoulder Injury
Josh Hader

Set to Return from Injured List on Tuesday
CFB

SEC Coach Calls Buster Faulkner a "Home-Run Hire"
CFB

Auburn a Sleeper in the SEC Under Alex Golesh?
CFB

Noah Fifita Primed for Strong 2026 Campaign
CFB

Oregon Assistant Coach Charged with DUII, Reckless Driving
CFB

Tight End Nick Pollack Commits to Clemson
Akshay Bhatia

Needs the Driver to be True in Ohio
Aaron Rai

Primed to take on the Memorial Tournament
J.J. Spaun

Rebounded at Charles Schwab Challenge
Xander Schauffele

One to Watch This Week in Ohio
Elly De La Cruz

to Miss 2-4 Weeks of Action
Chase Burns

is Scratched Due to Illness
Deiveson Figueiredo

Suffers Second-Round Submission Loss
Song Yadong

Gets Second-Round Submission Win
Zhang Mingyang

Suffers Back-To-Back Losses
Alonzo Menifield

Gets Back In The Win Column
Tallison Teixeira

Suffers First-Round Knockout Loss
Sergei Pavlovich

Scores First-Round Knockout Win
Cameron Smotherman

Suffers Third Loss In A Row
Edwin Arroyo

Reds Promote Top Infield Prospect Edwin Arroyo, Viewed as Priority Pick Up Ahead of MLB Debut
Kai Asakura

Earns His First UFC Win
Elly De La Cruz

Placed on IL with Right Hamstring Tightness
Denny Hamlin

Earns the first Nashville Cup Series Victory of his Career on Sunday
Christopher Bell

Finishes as the Runner-Up at Nashville
Chase Briscoe

Earns First Career Podium Finish at Nashville
Ryan Blaney

Scores A Solid Top-10 Finish at Nashville
Kyle Larson

Top-10 Streak at Nashville Ends after Late Flat Tire Spin
Elly De La Cruz

Exits with Hamstring Tightness
Tyler Reddick

Is One of the Top Favorites to Win at Nashville
Kyle Larson

May Continue his Top-10 Consistency at Nashville this week
Christopher Bell

Is One of the Top Competitors for the Win at Nashville
Chase Briscoe

Is A Must Start for Nashville DFS Lineups
Chase Elliott

has Plenty of Upside for Nashville DFS Lineups
William Byron

Is William Byron A Playable DFS Option for Nashville Lineups?
Carson Hocevar

Is Likely to have Another Solid Result at Nashville
NASCAR

Should Fantasy Players Roster Bubba Wallace at Nashville?
Chris Buescher

Is A Decent All-Around DFS Option for Nashville Lineups
Daniel Suarez

is Likely to Drop Positions during the Cracker Barrel 400
Garrett Crochet

Suffers Setback, Likely to Undergo MRI for Lat Tightness
Denny Hamlin

Could Denny Hamlin Dominate at Nashville?
Ryan Blaney

Is a DFS Tournament Option at Nashville
Ty Gibbs

Don't Overlook Ty Gibbs at Nashville
Joey Logano

Could Show Life at Nashville
Ross Chastain

Needs a Good Run at Nashville
Chet Holmgren

Fails to Step Up in the Season Finale
Cason Wallace

Ends Postseason with Strong Showing
Shai Gilgeous-Alexander

Caps MVP Season with Game 7 Exit
Stephon Castle

Continues Postseason Run with 16 Points
Julian Champagnie

Shines in Series-Clinching Win
De'Aaron Fox

Provides Secondary Punch in Game 7 Triumph
Victor Wembanyama

Earns Conference Finals MVP in Spurs' Game 7 Win
NBA

Warriors Prioritize Depth Around Returning Steve Kerr
Donovan Mitchell

Remains Cleveland's Top Priority
Adou Thiero

Remains a Lakers Development Project
NBA

76ers Hire Mike Gansey as President of Basketball Operations
NBA

Chicago Bulls Explore Kevin Young as Coaching Candidate
Kyrie Irving

Reports He's Nearing Full Strength in ACL Recovery
Lane Hutson

Posts a Power-Play Assist in Game 5 Loss
Cole Caufield

Nets a Power-Play Goal in Season-Ending Loss
Seth Jarvis

Closes Out East Finals With Multi-Point Game
Logan Stankoven

Notches Three Points in Big Game 5 Win
Taylor Hall

Racks Up Three Points in Series-Clinching Win
Frederik Andersen

Remains Stellar as Hurricanes Clinch Finals Berth
Jacob Gonzalez

is Heading to the Big Leagues
Munetaka Murakami

Exits with Hamstring Tightness
Mitchell Robinson

Plans to Play in Game 1 After Finger Surgery
Eury Pérez

Eury Perez is Placed on 15-Day Injured List
Deiveson Figueiredo

Set For UFC Macau Main Event
MMA

Yadong Song Returns At UFC Macau
Alonzo Menifield

An Underdog At UFC Macau
Zhang Mingyang

Set For UFC Macau Co-Main Event
Tallison Teixeira

Looks To Win Back-To-Back Fights
Sergei Pavlovich

A Favorite At UFC Macau
Cameron Smotherman

Looks To Bounce Back
Kai Asakura

Looks To Get Back In The Win Column
CFB

Faizon Brandon In Position to Start Week 1
CFB

Dane Weber Commits to Cal
CFB

Joey McGuire Attempts to Add Texas to Schedule
CFB

Mike Leach on 2027 College Football Hall of Fame Ballot
CFB

Maryland, Baylor Schedule Home-and-Home
CFB

Taron Dickens Decommits From North Carolina
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF