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Saturday Football Matchups Analysis - Week 16

Saturday football starts/sits and matchups analysis for Week 16 of the NFL season. Which fantasy football players start or sit for fantasy football lineups.

I hope everyone is enjoying a restful holiday season! Although Thursday Night Football has concluded for the 2019 NFL season, there are still a bevy of games to be played on Saturday in Week 16 that will determine the fates of fantasy owners who have made it thus far without being eliminated from the playoffs.

Fortunately, RotoBaller has you covered ahead of the Saturday triple-header to provide lineup advice that could make or break your championship run.

Let's dive in to some matchup analysis for the trio of Saturday football games in Week 16! You can read the Sunday game breakdowns as well by Chris O'Reilly and Pierre Camus.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Houston Texans @ Tampa Bay Buccaneers

Date and Start Time: Saturday, December 21 at 1:00 PM ET

Notable Injuries and Status:

Offensive and Defensive Rankings:

Texans Buccaneers
Passing Yards 11th 1st
Rushing Yards 7th 27th
Pass Defense 28th 30th
Rush Defense 19th 1st

 

Buffalo Bills @ New England Patriots

Date and Start Time: Saturday, December 21 at 4:30 PM ET

Notable Injuries and Status:

Offensive and Defensive Rankings:

Bills Patriots
Passing Yards 28th 9th
Rushing Yards 5th 19th
Pass Defense 3rd 2nd
Rush Defense 10th 7th

 

Los Angeles Rams @ San Francisco 49ers

Date and Start Time: Saturday, December 21 at 8:15 PM ET

Notable Injuries and Status:

Offensive and Defensive Rankings:

Rams 49ers
Passing Yards 6th 13th
Rushing Yards 24th 2nd
Pass Defense 9th 1st
Rush Defense 23rd 21st

 

Must Starts

Top Performers That Have To Be In Your Lineups

Deshaun Watson (QB, HOU)

Watson will poke holes in the Buccaneers horrid passing defense like it is Swiss cheese. Start him with confidence as a top-three option at the quarterback spot.

DeAndre Hopkins (WR, HOU)

Similar to the man throwing him the football, Hopkins will undoubtedly prosper against a Tampa defense with no ability to shut down opposing wideouts and he should remain a fixture in fantasy lineups.

Cooper Kupp (WR, LAR)

Odds are good that Kupp will either finish Week 16 with his exceptionally high floor of receptions, a score, or both. While one of his dud games did come against San Francisco back in Week 6, no fantasy owners is considering sitting Kupp in (preemptively) their championship game.

George Kittle (TE, SF)

We know by this point how much of a fantasy stud Kittle is. In case you forgot, Kittle accounted for 67 percent of the 49ers' receiving yardage last week on a ridiculous 17 targets and should see heavy volume when the team faces off against an NFC West rival.

 

Solid Options/Sleepers

Which Players Will Have Solid Games and Which Could Surprise?

Solid Option: Jameis Winston (QB, TB)

Despite Tampa's receiving core being absolutely decimated by injuries, the matchup is too good to not put Winston as a strong start this week. The former Seminole has only thrown for less than 300 passing yards and a score once since the Buccaneers Week 7 bye and Houston is a high-powered offense ready to battle in a shootout game-script.

Solid Option: Devin Singletary (RB, BUF)

Fantasy owners are chasing the volume when they consider starting Singletary, as he has had snap rates of at least 70 percent over his last three games. He deserves RB2 consideration despite facing a stout New England front seven.

Solid Option: Todd Gurley (RB, LAR)

Gurley has been on fire as of late with head coach Sean McVay seeming to find more creative ways to use him on the field. The 2015 NFL Draft's tenth overall pick will get the lion's share of Los Angeles' carries and should add on to his three game touchdown streak.

Solid Option: Raheem Mostert (RB, SF)

The 49ers have treated Mostert as his if he has earned the starting running back gig for San Francisco, handing him the ball no less than ten times in his last three games. With some certainty about who will get the bulk of the team's rush attempts, Mostert is a valuable fantasy asset.

Solid Option: Breshad Perriman (WR, TB)

No Mike Evans, no Chris Godwin, no problem. Perriman has stepped up big time for a Buccaneers offense that desperately needs a playmaker, exploding to the tune of five receptions for 113 yards and three scores in a Week 15 tilt with the Detroit Lions.

Solid Option: Julian Edelman (WR, NE)

Fantasy owners will need to keep a close eye on whether Edelman actually plays this week or New England opts to rest him ahead of a playoff run. If he is active, Edelman will continue to be a PPR scoring machine with the absurd number of targets he is averaging this season.

Solid Option: Robert Woods (WR, LAR)

Woods' ability to produce will hinge on whether 49ers defensive back Richard Sherman has fully recovered from a hamstring injury that kept him sidelined in Week 15. If Sherman is stymied, fantasy owners can consider Woods a flex option with upside.

Sleeper: Will Fuller (WR, HOU)

The prototypical boom or bust play in fantasy football, Fuller has a greater likelihood of fulfilling the boom side of the equation against a Buccaneers secondary that gives up the most fantasy points to opposing wide receivers.

Sleeper: Emmanuel Sanders (WR, SF)

So long as he can avoid coverage from defensive back Jalen Ramsey, Sanders should bounce back from a paltry two reception, nine yard effort in the upset loss versus Atlanta last week. Although his upside isn't anything more than a WR2, consider him a flex option if you don't have better options available.

Sleeper: O.J. Howard (TE, TB)

The absence of capable pass catchers in Tampa's receiving core due to injuries has opened up the door for Howard to make an impact, but his usage to date hasn't exactly inspired much confidence in the third-year pro.

 

Consider Sitting

Players To Avoid Putting In Your Lineup If Possible

Josh Allen (QB, BUF)

Allen has been a matchup play for fantasy owners who can exploit vulnerable defenses, but New England is the squad that can force him to throw for under 200 yards and plenty of turnovers (such as three interceptions back in Week 4).

Tom Brady (QB, NE)

I didn't expect the day when I would put Brady on the "Consider Sitting" list to come this season, but it's impossible to ignore the lack of productivity that has come from New England's signal-caller over the last few weeks. Buffalo is an especially hard draw to project Brady as anything more than a QB2 ahead of Saturday.

Jared Goff (QB, LAR)

The regression is noticeable in Goff, who simply hasn't looked sharp in making on point throws in tight windows. San Francisco is such a crew that will keep throwing lanes tight and pose trouble for Goff returning fantasy points for his owners.

Jimmy Garoppolo (QB, SF)

While we have seen flashes from Garoppolo, the more likely game plan for the 49ers offense will be to hand the football off to their most capable rusher and churn out yardage on the ground. Garoppolo will be a game-script dependent option in Week 16.

Carlos Hyde/Duke Johnson (RBs, HOU)

What Tampa's defense lacks in ability to stop the pass it more than makes up for in stymieing opposing running backs. Neither Hyde or Johnson have any safe floor in this matchup and should be avoided at all costs.

Ronald Jones/Peyton Barber (RBs, TB)

The Buccaneers running back who will finish with the better fantasy day by the time the conclusion of Week 16 comes around is largely unclear, but neither inspire much hope as fantasy options even with head coach Bruce Arians saying he intends to involve his backs in the team's passing attack against Houston.

Frank Gore (RB, BUF)

The Bills backfield is Devin Singletary's to lose, making Gore largely an afterthought barring the team accumulating a hefty lead.

Patriots Running Backs (RBs, NE)

New England's offense no longer carries the label of being high-powered, removing the scoring upside from any of their running backs that was by and large the most attractive feature of that group in fantasy football.

Tevin Coleman/Matt Breida (RBs, SF)

Coleman and Breida have been receiving change of pace work since Raheem Mostert has proven to head coach Kyle Shanahan that he deserves to be the top dog in the 49ers backfield. Breida may carry more value than Coleman at this point, but that isn't saying much.

Phillip Dorsett / Mohamed Sanu / N'Keal Harry (WRs, NE)

The recent struggles of quarterback Tom Brady have left his receiving core out to dry when it comes to their fantasy production. The potential absence of Julian Edelman could lead to a resurgence, but which wideout will contribute enough to be a flex option is a dart throw.

Kenny Stills (WR, HOU)

Since being described as one of the hottest waiver pickups in the wake of Will Fuller getting injured, Stills has largely been a disappointment, especially recently with a combined 11 targets in his last four games.

John Brown/Cole Beasley (WRs, BUF)

Either Brown or Beasley could receive a healthy share of looks against a tough divisional rival Patriots secondary. The question of how productive said looks will be is a whole other matter and likely to lead to disappointment for those fantasy owners who start them.

Darren Fells (TE, HOU)

Although Tampa Bay is a juicy matchup for fantasy tight ends, the split in receiving usage between Jordan Akins and Fells has contributed to the latter largely falling off the face of the earth for fantasy purposes.

Cameron Brate (TE, TB)

Much like his tight end teammate O.J. Howard, Brate could be looked at to fill the void left by injuries to Tampa's pass catchers. Nonetheless, he will be a touchdown-dependent option that should be benched in favor of better options.

Gerald Everett / Tyler Higbee (TEs, LAR)

The 49ers Defense gives up the third-fewest fantasy points to tight ends and Everett's return from injury creates an unpredictable situation for determining which tight end will get the most looks. Either could be started in a pinch, but only as a TE2 play.

More Lineup Prep




REAL-TIME FANTASY NEWS

Pat Bryant

Working With Training Staff This Offseason
Jacoby Brissett

in Communication With Cardinals Despite Skipping Workouts
Daniel Jones

Could Take Part in 7-on-7 Drills at OTAs
Tyler Glasnow

Dodgers Put Tyler Glasnow on Injured List With Back Spasms
Sam Merrill

Iffy for Game 3 on Saturday
Anthony Edwards

Rejoins Starting Lineup Friday
Kevin Huerter

Likely to Remain Out Saturday
Jarred Vanderbilt

Considered Questionable for Saturday
Jalen Williams

Ruled Out for Game 3 Against Lakers
Ayo Dosunmu

Cleared to Play Friday
Anthony Edwards

Available Friday Night
Joel Embiid

is Returning for Game 3 on Friday
Brandon Ingram

Undergoes Heel Surgery
Josh Hart

is Available to Play in Game 3
OG Anunoby

is Downgraded to Out for Game 3 on Friday
Mitchell Robinson

is Returning for Game 3
Mats Zuccarello

Expected to Play Saturday
Joel Eriksson Ek

to Be a Game-Time Decision Saturday
Jonas Brodin

Still Out Saturday
Josh Manson

Could Return Saturday
Kaedan Korczak

Scratched for Game 3 Against Ducks
Radko Gudas

Likely to Remain Out Friday
Sam Carrick

Won't Play Friday
Isiah Pacheco

Can Isiah Pacheco Re-Establish His Dynasty Value in Detroit?
Rico Dowdle

Dynasty Ceiling Limited By Backfield Committee in Pittsburgh
Rashid Shaheed

a High-Risk, High-Reward Buy-Low Candidate for Dynasty Managers
Marcus Mariota

Is Marcus Mariota Worth Stashing as an Injury Replacement in Dynasty Leagues?
Jacoby Brissett

a Clear Sell-High Candidate for Dynasty Managers
Blake Snell

to Make Season Debut for Dodgers on Saturday
Najee Harris

Can Najee Harris Re-Establish Some Dynasty Value in 2026?
Cole Ragans

Royals Place Cole Ragans on Injured List With Elbow Impingement
Breece Hall

Jets Sign Breece Hall to Three-Year Extension Worth $45.75 Million
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
Nick Lodolo

Officially Activated, Making Season Debut on Friday
Denver Broncos

Broncos Sign GM George Paton to New Five-Year Deal
Brandon McManus

Packers Release Kicker Brandon McManus
New York Jets

Jets Talking to a "Number of Veteran Quarterbacks"
Travis Etienne Jr.

a Reliable Dynasty Starter Entering First Season With Saints
Kenneth Gainwell

Is Kenneth Gainwell's Dynasty Stock Still Rising After Offseason Change of Scenery?
Mac Jones

a Deep-League Dynasty Stash Candidate
Tez Johnson

Facing Uphill Battle for Playing Time in Tampa Bay
Jared Goff

Remains a High-Floor Dynasty QB2 Heading into 2026
De'Von Achane

Remains a High-End Dynasty RB Despite Uncertain Supporting Cast
Xavier Worthy

Chiefs Limited Xavier Worthy's Usage After Injury Last Year
Rashee Rice

Chiefs Not Ready to Discuss Extension With Rashee Rice?
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
Austin Reaves

Scores 31 Points in Game 2 Defeat
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
Chet Holmgren

Anchors Thunder Past Lakers in Game 2
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
Tobias Harris

Stays Hot in Game 2 Victory
Cade Cunningham

Pushes Pistons to 2-0 Series Lead
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
Jarrett Allen

Provides Bright Spot in Cavs' Game 2 Loss to Pistons
CFB

Rasheem Biles an Instant Impact Player for Texas
James Harden

Struggles in Game 2 Loss
Donovan Mitchell

Finishes Game 2 Loss with 31 Points
Gradey Dick

Open to Trade Away From Toronto
Michael Porter Jr.

Wants to Stay in Brooklyn
Dan Vladar

Looks to Return to Winning Ways Thursday
Connor Dewar

Penguins Re-Sign Connor Dewar for Two Years
Mikko Rantanen

Played Through Torn MCL Late in the Season
Rasmus Dahlin

Ready to Go Friday
Alexander Nikishin

Set to Return Thursday
Christian Dvorak

Available Thursday
Owen Tippett

Remains Out Thursday
Roman Anthony

Heading for the Injured List
CFB

Sam Leavitt Expected to Be Full-Go for Fall Camp
Tarik Skubal

Could Return in 4-6 Weeks After Successful Elbow Surgery
Cole Ragans

Royals Hopeful That Cole Ragans Makes his Next Start
Mark Stone

Nets Late Power-Play Goal in Losing Effort
Leo Carlsson

Pots Game-Winner Wednesday Night
Juraj Slafkovsky

Ends Point Drought in Game 1 Loss
Bowen Byram

Ties Franchise Record With Fourth Postseason Goal
Zach Benson

Posts Second Consecutive Multi-Point Game
Rasmus Dahlin

"Seems Fine" After Early Exit on Wednesday
Emilio Pagán

Emilio Pagan has Grade 2 Hamstring Strain, Expected to Miss 4-8 Weeks
Joe Ryan

Listed as Scheduled Starter for Saturday Against Cleveland
Tyler Glasnow

Not Expected to Land on the Injured List
Framber Valdez

Suspension Reduced to Five Games
Nils Hoglander

Will Miss World Championship Due to Injury
Framber Valdez

Suspended Six Games
Tyler Glasnow

Exits Early on Wednesday With Back Pain
CFB

Brauntae Johnson the Next Star in Notre Dame's Secondary?
CFB

Ethan Barbour a Name to Know in Georgia's Tight End Room
CFB

Payton Pierce Next Up at Linebacker for Ohio State
CFB

Javin Gordon to Play Significant Role for Tennessee?
CFB

Tanook Hines Stepping into WR1 Role for USC
CFB

Rueben Owens II has "Star Potential" in Fourth Campaign
Brandon Woodruff

has Fluid Drained From his Right Shoulder
Brandon Woodruff

to Resume Throwing on Saturday, Return Imminent?
Carlos Correa

to Have Season-Ending Ankle Surgery
Jacob Misiorowski

Listed as Friday's Probable Starter
Logan Webb

Dealing With Knee Discomfort
Carlos Correa

Expected to Miss Significant Time With Ankle Injury
Collin Morikawa

Withdraws From Truist Championship
Xander Schauffele

Carries Elite Form Into Quail Hollow
Hideki Matsuyama

Looks to Bounce Back at Truist Championship
Matt Fitzpatrick

Secures Third Win of 2026 Season
Patrick Cantlay

Continues Playing Well Heading to Truist Championship
Ludvig Aberg

Returns to Action For Truist Championship
Justin Thomas

Searching for Consistency at Quail Hollow
Jordan Spieth

Looks to Break Through at Quail Hollow
Adam Scott

Brings Strong Form to Quail Hollow
Robert MacIntyre

a Steady Option at Truist Championship
Jason Day

Looks to Overcome Approach Struggles at Quail Hollow
Akshay Bhatia

Looks for Complete Game at Truist Championship
Emilio Pagán

Emilio Pagan Headed for Injured List With Hamstring Injury
Emilio Pagán

Emilio Pagan Carted Off With Apparent Hamstring Injury on Tuesday
Justin Rose

to Continue Mid-Season Club Change at Truist Championship
Si Woo Kim

is Back to Peak Form Ahead of Truist Championship
Sam Burns

to Bounce Back at Truist Championship
Cameron Young

Looks to Carry Dominance to Quail Hollow
Rory McIlroy

Returns to Familiar Stomping Grounds This Week at Quail Hollow
Chris Gotterup

Looking to Bounce Back at Quail Hollow
Tommy Fleetwood

Looking For Better Iron Play at Quail Hollow
CFB

Mario Craver Enters No. 1 Wide Receiver Role for Marcel Reed
CFB

LaNorris Sellers a Strong Rebound Candidate in 2026
CFB

Cam Coleman Poised for Monster Year at Texas?
CFB

Will Hammond Pushing to Be Ready for Week 1
Alex Fitzpatrick

Looking to Keep Up Ball-Striking Output at Quail Hollow
CFB

Notre Dame Leads College Football in Returning Snaps
CFB

Two Ole Miss Football Players Arrested, Charged with DUI
Ben Griffin

Looks Solid on the Surface Heading to Charlotte
Chase Elliott

Earns his Second Texas Motor Speedway Victory
Denny Hamlin

Misses Out on Winning at Texas
Alex Bowman

Finishes Third for the Second Week in a Row at Texas
Tyler Reddick

Earns Seventh Top-Five Finish of the Season at Texas
Chris Buescher

Scores his First Career Texas Finish in the Top Five
CFB

Bryce Underwood in Better Situation Entering Sophomore Season
CFB

Nico Iamaleava Emerging as Leader, Playmaker for UCLA
Jack Della Maddalena

Gets Dominated At UFC Perth
Carlos Prates

Shines At UFC Perth
Beneil Dariush

Suffers A First-Round TKO Loss
Quillan Salkilld

Remains Unbeaten In The UFC
Tim Elliott

Drops Decision At UFC Perth
Steve Erceg

Wins Back-To-Back Fights
Ollie Schmid

Suffers First-Round TKO Loss
Marwan Rahiki

Remains Unbeaten
Christopher Bell

Is Christopher Bell Worth Rostering for Texas Lineups?
William Byron

Might have the Speed to Compete for the Win at Texas
Joey Logano

Provides Solid Upside for Texas DFS Lineups
Chase Briscoe

Could Chase Briscoe be A Sneaky Pick for Texas Lineups?
Ty Gibbs

Should DFS Managers Roster Ty Gibbs at Texas?
Daniel Suarez

Is Daniel Suarez Worth Rostering After Career-Best Starting Position at Texas?
Kyle Busch

Is a DFS Risk Starting in the Top 10 at Texas
Tyler Reddick

One of the Favorites to Win at Texas
Chase Elliott

Could Contend for Another Win at Texas
Carson Hocevar

on Pole at Texas
NASCAR

Bubba Wallace Wrecks in Practice at Texas
Chris Buescher

Looking to Continue Strong Run at Texas
Austin Dillon

Blows Engine in Practice at Texas
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF