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The top daily fantasy football lineup picks for DraftKings in Week 2. Ben Rolfe's NFL DFS analysis and sleepers for building optimal DFS rosters.
Once again there are tons of contests on both major DFS sites. Below are my DraftKings DFS Lineup Picks for Week 2.
These DraftKings lineup recommendations are based on matchups, week 1 performances, overall upside/talent levels, opportunity, and other factors such as Vegas odds, home field advantage, and more. There are quite a few great value plays available, so read on to find out which players are the best for Week 2.
Good luck with your DraftKings DFS lineups!
Be sure to check all of our fantasy football rankings for 2025:- 2025 fantasy football rankings
- Running back (RB) fantasy football rankings
- Wide receiver (WR) fantasy football rankings
- Tight end (TE) fantasy football rankings
- Quarterback (QB) fantasy football rankings
- FLEX fantasy football rankings
- Defense (D/ST) fantasy football rankings
- Kicker (K) fantasy football rankings
- Dynasty fantasy football rankings
DraftKings DFS Quarterbacks - Week 2 Picks
Andrew Luck - IND @ WAS (DK $6,200)
Week 1 gave us a very interesting to look into how the Colts season may progress in 2018. With the run game non-existent the responsibility fell on Luck to move the ball, even when they were leading. Luck threw 53 times, completing 39 passes for 319 yards and two touchdowns. Had Jack Doyle not fumbled late in the game then he likely would have added more yards and another touchdown. The Washington Redskins defense looked strong in week 1 but that was more due to the Arizona Cardinals offense than anything. I expect Luck to be able to have success against them and there is a real chance he will throw another 50 times in this game.
Case Keenum - DEN vs OAK (DK $5,800)
Despite throwing three interceptions last week Keenum still managed to put up a 25 point game against a so-so Seattle defense. The great thing for Keenum is that Oakland’s defense may be even worse, as the LA Rams seemed to be able to move the ball at will against them. Jared Goff's line Monday could have looked incredible if he had connected with Robert Woods on some deep shots. Oakland managed just one sack and two quarterback hits on Goff, so I expect Keenum to have all the time in the world to get the ball in the hands of his seemingly numerous offensive weapons. The only limited factor to Keenum's value in this game may be if the Broncos get up big early, and they decide to keep the ball on the ground and pair back their offense in the second half.
DraftKings DFS Running Backs - Week 2 Picks
James Conner - PIT vs KC (DK $6,700)
Conner is not quite the value he was last week after his monster outing in Cleveland. This week he gets a home matchup against the Kansas City Chiefs, who had their own problems against running backs. Melvin Gordon and Austin Ekeler combined for 103 yards rushing on 20 attempts and 189 receiving on 14 receptions. Conner is unlikely to split time like the Chargers running backs did meaning he could be in for another big day against a porous Chiefs defense. The Steelers are going to need to do two things in this game. Firstly, they will need to go toe-to-toe with the Chiefs offense, and there should be a ton of points, as shown by the over/under being around 52 points in most places. Secondly, they will need to play some ball control offense and that will mean Conner seeing plenty of the ball.
Adrian Peterson - WAS vs IND (DK $5,500)
If there was any doubt entering the season about Peterson, those were put to bed in week 1 as he rushed 26 times for 96 yards and a touchdown. The Redskins seem to have committed to riding Peterson for as long as he can carry them. I do not expect him to have quite as many carries in this game, as the game should be closer. However, he is facing a Colts team who gave up an average of 5.6 yards per rush and a touchdown to Joe Mixon. Alex Smith knows how to get running backs going, after having the NFL leader on his team last year, and I expect Peterson to have another big game, and likely add another touchdown in week 2.
Austin Ekeler - LAC @ BUF (DK $4,400)
The Buffalo Bills were on average a point and a half a game worse against running backs than any other team in 2017. It is hard to read to much into the Bills performance against the rush last week, as the Ravens had their way with them in the air, so did not require the ground game until the game was in the bag. Ekeler is a gamble because he is not assured of touches. However, his utility in the passing game, and the likelihood he sees the majority of time if the Chargers are up big, makes him an interesting DraftKings option, especially at this price.
DraftKings DFS Wide Receivers - Week 2 Picks
Emmanuel Sanders - DEN vs OAK (DK $6,200)
Sanders had a big first game with his new quarterback, catching 10 of his 11 targets for 135 yards and a touchdown. Sanders and Demaryius Thomas saw 21 of the Broncos 36 targets, which is a trend I fully expect to happen going forward. The Rams main wide receivers saw plenty of targets, and they saw them deep the down the field because the Raiders were unable to get to the quarterback. Sanders looks to have already won the trust of Keenum, and playing at home means this offense has the chance to gas the Raiders defense, opening up opportunities for big plays. Another 100 yard day with a touchdown looks more than possible for Sanders this week.
Quincy Enunwa - NYJ vs MIA (DK $4,700)
The tough thing about looking at the Dolphins this week is that their game last week was such a mess that it is really hard to read anything into this it. However, what you cannot doubt is the way that Enunwa was used in the Jets offense on Monday night. Enunwa saw 10 of the Jets 21 targets, pulling in six passes for 65 yards and a touchdown. Playing at home does provide an advantage for the Jets, especially with the Dolphins having to travel after that crazy game. At this price it makes sense to gamble on Enunwa seeing somewhere in the region of 50% of the Jets targets again in week 2.
DraftKings DFS Tight Ends - Week 1 Picks
Jordan Reed - WAS vs IND (DK $5,000)
I think the over/under on this Redskins/Colts line is far too low at 46. This game has every potential to be a back-and-forth slug fest and Reed looks like he may be one of Smith's go to guys when he is healthy. Reed saw five targets, catching four of them for 48 yards and a touchdown. Had it not have been that the Redskins got up big then Reed could have seen even more targets. When he is healthy Reed is one of the best tight ends in the business, and one of a limited number who is not touchdown dependent week-to-week.
Austin Hooper - ATL vs CAR (DK $2,900)
With Reed being a relatively high-priced tight end I wanted to recommend a lower-priced guy who has a high ceiling. Hooper provides exactly that opportunity, having seen two officially recorded and a third not recorded red-zone target in week one. Hooper should have drawn another flag on a defensive pass interference that he was favorite to catch until he was bumped by an Eagles defender. As long as Hooper remains the Falcons second red-zone threat he will make for an interesting DFS option week-to-week.
DraftKings DFS Defenses - Week 1 Picks
Denver Broncos vs Oakland Athletics (DK $3,300)
The Raiders offensive line appears to have held up well against the Rams, but the penalty count demonstrates their issues. The Raiders had five offensive holding penalties and three false starts. Those penalties are almost a direct consequence of a team struggling with a defensive line. The Broncos defensive line may not be as good as the Rams but they have some really talented players, who can cause this Raiders offense a lot of trouble. That pressure will lead to mistakes and could lead to a superb day for the Broncos secondary.
Minnesota Vikings vs Green Bay Packers (DK $2,600)
This pick almost entirely depends on who is playing quarterback for the Green Bay Packers. Even if Rodgers plays this defense has a chance to have a good day. However, if Deshone Kizer is the quarterback then we could see a massacre. Kizer was 4-for-7 with an interception against a defense that is good but no where near the quality of this Vikings defense. If Kizer is the quarterback then this defense is likely to be extremely highly owned and may be a team to swerve away from in GPP.
