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DraftKings Daily Fantasy Football Picks (Week 2): NFL DFS Lineups

The top daily fantasy football lineup picks for DraftKings in Week 2. Ben Rolfe's NFL DFS analysis and sleepers for building optimal DFS rosters.

Once again there are tons of contests on both major DFS sites. Below are my DraftKings DFS Lineup Picks for Week 2.

These DraftKings lineup recommendations are based on matchups, week 1 performances, overall upside/talent levels, opportunity, and other factors such as Vegas odds, home field advantage, and more. There are quite a few great value plays available, so read on to find out which players are the best for Week 2.

Good luck with your DraftKings DFS lineups!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 2 Picks

Andrew Luck - IND @ WAS (DK $6,200)

Week 1 gave us a very interesting to look into how the Colts season may progress in 2018. With the run game non-existent the responsibility fell on Luck to move the ball, even when they were leading. Luck threw 53 times, completing 39 passes for 319 yards and two touchdowns. Had Jack Doyle not fumbled late in the game then he likely would have added more yards and another touchdown. The Washington Redskins defense looked strong in week 1 but that was more due to the Arizona Cardinals offense than anything. I expect Luck to be able to have success against them and there is a real chance he will throw another 50 times in this game.

Case Keenum - DEN vs OAK (DK $5,800)

Despite throwing three interceptions last week Keenum still managed to put up a 25 point game against a so-so Seattle defense. The great thing for Keenum is that Oakland’s defense may be even worse, as the LA Rams seemed to be able to move the ball at will against them. Jared Goff's line Monday could have looked incredible if he had connected with Robert Woods on some deep shots. Oakland managed just one sack and two quarterback hits on Goff, so I expect Keenum to have all the time in the world to get the ball in the hands of his seemingly numerous offensive weapons. The only limited factor to Keenum's value in this game may be if the Broncos get up big early, and they decide to keep the ball on the ground and pair back their offense in the second half.

 

DraftKings DFS Running Backs - Week 2 Picks

James Conner - PIT vs KC (DK $6,700)

Conner is not quite the value he was last week after his monster outing in Cleveland. This week he gets a home matchup against the Kansas City Chiefs, who had their own problems against running backs. Melvin Gordon and Austin Ekeler combined for 103 yards rushing on 20 attempts and 189 receiving on 14 receptions. Conner is unlikely to split time like the Chargers running backs did meaning he could be in for another big day against a porous Chiefs defense. The Steelers are going to need to do two things in this game. Firstly, they will need to go toe-to-toe with the Chiefs offense, and there should be a ton of points, as shown by the over/under being around 52 points in most places. Secondly, they will need to play some ball control offense and that will mean Conner seeing plenty of the ball.

Adrian Peterson - WAS vs IND (DK $5,500)

If there was any doubt entering the season about Peterson, those were put to bed in week 1 as he rushed 26 times for 96 yards and a touchdown. The Redskins seem to have committed to riding Peterson for as long as he can carry them. I do not expect him to have quite as many carries in this game, as the game should be closer. However, he is facing a Colts team who gave up an average of 5.6 yards per rush and a touchdown to Joe Mixon. Alex Smith knows how to get running backs going, after having the NFL leader on his team last year, and I expect Peterson to have another big game, and likely add another touchdown in week 2.

Austin Ekeler - LAC @ BUF (DK $4,400)

The Buffalo Bills were on average a point and a half a game worse against running backs than any other team in 2017. It is hard to read to much into the Bills performance against the rush last week, as the Ravens had their way with them in the air, so did not require the ground game until the game was in the bag. Ekeler is a gamble because he is not assured of touches. However, his utility in the passing game, and the likelihood he sees the majority of time if the Chargers are up big, makes him an interesting DraftKings option, especially at this price.

 

DraftKings DFS Wide Receivers - Week 2 Picks

Emmanuel Sanders - DEN vs OAK (DK $6,200)

Sanders had a big first game with his new quarterback, catching 10 of his 11 targets for 135 yards and a touchdown. Sanders and Demaryius Thomas saw 21 of the Broncos 36 targets, which is a trend I fully expect to happen going forward. The Rams main wide receivers saw plenty of targets, and they saw them deep the down the field because the Raiders were unable to get to the quarterback. Sanders looks to have already won the trust of Keenum, and playing at home means this offense has the chance to gas the Raiders defense, opening up opportunities for big plays. Another 100 yard day with a touchdown looks more than possible for Sanders this week.

Quincy Enunwa - NYJ vs MIA (DK $4,700)

The tough thing about looking at the Dolphins this week is that their game last week was such a mess that it is really hard to read anything into this it. However, what you cannot doubt is the way that Enunwa was used in the Jets offense on Monday night. Enunwa saw 10 of the Jets 21 targets, pulling in six passes for 65 yards and a touchdown. Playing at home does provide an advantage for the Jets, especially with the Dolphins having to travel after that crazy game. At this price it makes sense to gamble on Enunwa seeing somewhere in the region of 50% of the Jets targets again in week 2.

 

DraftKings DFS Tight Ends - Week 1 Picks

Jordan Reed - WAS vs IND (DK $5,000)

I think the over/under on this Redskins/Colts line is far too low at 46. This game has every potential to be a back-and-forth slug fest and Reed looks like he may be one of Smith's go to guys when he is healthy. Reed saw five targets, catching four of them for 48 yards and a touchdown. Had it not have been that the Redskins got up big then Reed could have seen even more targets. When he is healthy Reed is one of the best tight ends in the business, and one of a limited number who is not touchdown dependent week-to-week.

Austin Hooper - ATL vs CAR (DK $2,900)

With Reed being a relatively high-priced tight end I wanted to recommend a lower-priced guy who has a high ceiling. Hooper provides exactly that opportunity, having seen two officially recorded and a third not recorded red-zone target in week one. Hooper should have drawn another flag on a defensive pass interference that he was favorite to catch until he was bumped by an Eagles defender. As long as Hooper remains the Falcons second red-zone threat he will make for an interesting DFS option week-to-week.

 

DraftKings DFS Defenses - Week 1 Picks

Denver Broncos vs Oakland Athletics (DK $3,300)

The Raiders offensive line appears to have held up well against the Rams, but the penalty count demonstrates their issues. The Raiders had five offensive holding penalties and three false starts. Those penalties are almost a direct consequence of a team struggling with a defensive line. The Broncos defensive line may not be as good as the Rams but they have some really talented players, who can cause this Raiders offense a lot of trouble. That pressure will lead to mistakes and could lead to a superb day for the Broncos secondary.

Minnesota Vikings vs Green Bay Packers (DK $2,600)

This pick almost entirely depends on who is playing quarterback for the Green Bay Packers. Even if Rodgers plays this defense has a chance to have a good day. However, if Deshone Kizer is the quarterback then we could see a massacre. Kizer was 4-for-7 with an interception against a defense that is good but no where near the quality of this Vikings defense. If Kizer is the quarterback then this defense is likely to be extremely highly owned and may be a team to swerve away from in GPP.

 

More Weekly DFS Analysis




REAL-TIME FANTASY NEWS

Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
Micah Parsons

Expected to Miss the Early Part of the Season
Colby Parkinson

a Clear Dynasty Sell-High Candidate Entering 2026
Omarion Hampton

Poised for Year 2 Breakout in Los Angeles
Blake Corum

Dynasty Stock Rising After Encouraging 2025 Campaign
Jaxson Dart

Does Jaxson Dart Carry High-End Dynasty QB1 Upside?
David Montgomery

Dynasty Stock Rising Following Move to Houston
Chris Godwin Jr.

Can Chris Godwin Jr. Re-Establish His Dynasty Value in 2026?
Malik Willis

Not Set Up for Immediate Success in Miami
Terrance Ferguson

has Promising Receiving Skills in Crowded TE Room in L.A.
Brenton Strange

Is Brenton Strange a Top-15 Dynasty Tight End?
T.J. Watt

Steelers Ready to Move on From T.J. Watt?
Jacory Croskey-Merritt

Must Make Gains as Pass-Catcher to Take the Next Step
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Kaytron Allen

Could Kaytron Allen Take on a Big Role Right Away?
Demond Claiborne

Has Long-Term Appeal in Minnesota
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Adam Randall

to Contribute as a Pass-Catcher Right Away?
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Nicholas Singleton

Could Contribute Right Away
Bryce Lance

a Perfect Fit in New Orleans?
Mike Washington Jr.

Can Mike Washington Jr. Force a Backfield Split in Vegas?
Paul Reed

Makes Big Impact Off the Bench Wednesday
Adonai Mitchell

Unlikely to be Phased Out of Jets Offense
Daniss Jenkins

Contributes 19 Points As Starter
Cade Cunningham

Tallies 39 Points in Losing Effort
Tony Pollard

an Affordable Add for Contending Dynasty Managers
Max Strus

Notches 20 Points With Six Triples
Evan Mobley

Close to Triple-Double Wednesday
Mason Taylor

How Much Dynasty Value Will Mason Taylor Hold After Offensive-Heavy Draft?
Jarrett Allen

Records Double-Double in Game 5 Win
James Harden

Leads the Way for Cavaliers in Game 5 Victory
Quinn Hughes

Finishes Postseason With 15 Points
Matt Boldy

Posts Two Assists in Season-Ending Loss
Scott Wedgewood

Perfect in Relief Effort
Martin Necas

Records Another Multi-Point Game
Brett Kulak

Sends Avalanche Into Conference Finals
Brayden McNabb

Suspended for One Game
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
Juan Soto

Exits Wednesday's Game Early with Ankle Injury
Kevin Huerter

is Cleared to Return for Game 5
Caris LeVert

is Available for Game 5 on Wednesday
Duncan Robinson

is Out for Game 5
Keegan Murray

Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Sam Malinski

Set to Miss Second Straight Game
Artturi Lehkonen

Unlikely to Play Wednesday
Matthew Schaefer

Wins Calder Trophy
TOR

Maple Leafs Fire Head Coach Craig Berube
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

Comes Alive in Game 5 Against Timberwolves
Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Victor Wembanyama

Leads Spurs to Big Win in Game 5
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Mason McTavish

Delivers Two Assists Tuesday Night
Pavel Dorofeyev

Pots Two Goals in Vital Game 5 Win
Josh Doan

Records Two Assists in Game 4 Victory
Evgeni Malkin

Penguins Want Evgeni Malkin Back
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF