🖥 TAP TO SAVE 50% WITH CODE THANKS
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

DraftKings Daily Fantasy Baseball Picks (4/25/21): MLB DFS Lineups

Brandon Woodruff - Fantasy Baseball Rankings, MLB Injury News, DFS Lineup Picks

The top daily fantasy baseball lineup picks for DraftKings on 4/25/21. Euan Leith's MLB DFS analysis and sleepers for building optimal DFS rosters.

We've got a giant main slate with a dozen games starting at 1:05 pm Eastern. The Braves and Diamondbacks have a double dipper in Atlanta, so their game in this set will only go seven innings. In the grand scheme of things that may only cost us one at-bat, but we have seen ownership plummet for these seven inning games. That's a way to gain some leverage.

Rain is going to be a problem in the northeast today. I'll be shocked if Boston plays at all. I'm cutting this slate down to 11 games right now. That one is too risky for me to mess with. They can play in New York if they wait the rain out, but we have teams less willing to do that this year. There is a chance of light snow in Minneapolis. That's not going to be a good game with the cold and wind blowing in anyway. The wind is also blowing in in Wrigley and Cleveland. We do have a nice wind blowing out in Detroit and Atlanta though.

This article will provide you with my daily fantasy baseball lineup picks for DraftKings on 4/25/2021. The lineup will range from some of the elite players to mid-priced options and value plays. You can also check out today's FanDuel MLB DFS lineup picks and read more DFS advice and lineup picks for other sports too. It’s also important to monitor injury news and today's MLB starting lineups. If you have any questions or comments, contact me on Twitter.

Holiday Special! Save 50% on any Premium Pass using discount code THANKS. Win more with our DFS, Betting and Season-Long Premium Pass, get expert tools and advice from proven winners! GAIN ACCESS

 

DraftKings DFS Starting Pitchers

Brandon Woodruff - MIL at CHC ($9,400)

This will be Woodruff's 11th career start against the Cubs, but he only has one decision against them. Part of it is bullpen issues. Part of it was Woodruff not lasting long in starts, particularly early on in his career. The current Cubs roster is hitting a dismal .147 in 109 at-bats against Woodruff, so it's not a fluke. He has a career 2.95 ERA at Wrigley Field. With the wind blowing in, this looks like an elite spot for Woodruff with the way that he's been pitching this year. Woodruff has sparkling numbers across the board. A big reason for that is he has not allowed a ball hit on the barrel of an opponents bat yet. As you would expect, the hard hit percentage is also way down. I expect a really strong start out of Woodruff here.

Danny Duffy - KC at DET ($8,000)

Duffy has allowed just one earned run in 18 innings so far this year with 19 strikeouts. We have seen flashes of brilliance from Duffy here and there throughout his career. He has always been a highly-touted prospect, but has never really put anything together. There is some reason for optimism this year. Duffy's velocity is up across the board and there is a lot more movement on his four-seamer and curveball. And honestly, this is a dream matchup for Duffy. The Tigers are hitting a dismal .179 against southpaws this year and were completely shut down by fellow lefty Mike Minor on Friday. The Tigers are striking out an alarming 35.9% against lefties this year. Duffy may regress at some point, but it shouldn't start here.

Other Options: John Means ($8,900), Kohei Arihara ($7,000), Michael Kopech ($6,900)

 

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's RealTalkRaph on DraftKings - join in on the winning!

 

DraftKings DFS Infielders

Andrew Knizner - C, STL vs. CIN ($2,200)

Predicting who catches on Sunday afternoons can be a daunting task, but the Cardinals are still without Yadier Molina and Knizner has filled in pretty well for him. The price is low despite Luis Castillo getting absolutely destroyed by the Cardinals on Opening Day, and really not looking good in a start since. Knizner homered off of Castillo in the only game that he has started against him. For this low of a price, it's worth seeing if he can do it again.

Joey Votto - 1B, CIN at STL ($4,400)

Is Votto back? The four homers in a nice touch, but the .225 average leaves something to be desired. His walk rate is also the lowest of his career. Now the good news: The hard hit percentage is by far the best of his career and a .312 xBA suggests that Votto has been a little unlucky so far this year. The launch angle, exit velocity, and hard hit percentage are all at or above his marks during his heyday. Votto is absolutely mashing fastballs this year, which is exactly where Jack Flaherty has been struggling. History is on Votto's side too. He is 6-13 in his career against Flaherty.

Adam Frazier - 2B, PIT at MN ($4,400)

Frazier is firmly entrenched atop this Pirates lineup and has been one of the few bright spots in it thus far. Matt Shoemaker has always been a junkballer, but is has caught up to him in recent years. His 6.28 ERA looks bad, but the xERA of 7.23 suggests that he should be even worse. Opponents have a staggering 17% barrel percentage against Shoemaker so far. Frazier profiles well against Shoemaker's best pitches, the sinker and splitter. The other Frazier (Todd) is the only Pirate that profiles better, but you have to have some stones to run with the Toddfather right now.

J.D. Davis - 3B, NYM vs. WAS ($3,400)

Something is off with Patrick Corbin. His strikeout rate so far is by far the lowest rate of his career. Though the 10.95 ERA is a little bloated, his xERA is still a catastrophic 7.06. If there weren't a good track record attached to Corbin, he wouldn't even be in the majors right now. It's not even a velocity issue for Corbin. His velocity is fine. Hitters just aren't chasing his pitches anymore. His fastball and slider are getting crushed right now. I'll have a few five-man Mets stacks, but they will all start with Davis. Not only does Corbin struggle with right handed power, Davis has a .462 ISO with three homers in 26 career at-bats against Corbin. He may as well be hitting off a tee.

Eugenio Suarez - SS, CIN at STL ($5,300)

Normally I wouldn't go out of my way to run hitters at guys like Luis Castillo and Jack Flaherty, but they are both off this year. Both are suffering about a 1.5 MPH loss on the fastball from last year. What's even more concerning for Flaherty is that he is missing a lot of movement on his slider and fastball. The only thing worse than throwing a pitch slower is not having it move effectively. Suarez homered off of Flaherty on Opening Day, his third off of Jack in just 15 at-bats. This is DFS, people. If we aren't chasing homers, what the hell are we even doing out here?

 

DraftKings DFS Outfielders

Byron Buxton - OF, MN vs. PIT ($5,600)

I have been a Buxton truther since my beloved Twins drafted him and I caught a game that he played for Cedar Rapids back in 2013. His tools have never translated to major league success due to injuries and a free-swinging style that would make Kirby Puckett proud. The difference is that Kirby would swing at damn near everything, but he always made contact. That is what has eluded Buxton until now. His chase rate and K rate are far below his career numbers, even though he still doesn't walk. Buxton has an impossible 30.6 barrel percentage - the best in the majors - and is in the 100th percentile in xwOBA, xBA, xSLG, xISO, and hard hit percentage. Oh, and he's facing a pitcher that has given up 12 runs in nine major league innings. This is yet another smash spot for Buxton. Ride him until he cools off.

Michael Conforto - OF, NYM vs. WAS ($4,100)

Allow me to highlight one of the less obvious pieces of my Mets stack. Yes, I realize that Corbin has handled lefties fairly well in his career. Every lefty but Michael Conforto, that is. Conforto is 9-25 with five homers, 12 RBI, and a .640 ISO. Most will be on the right handed side of this Mets stack, but Conforto may be forgotten since he's a lefty. He is one of the few that has managed to get to Corbin.

Jorge Soler - OF, KC at DET ($3,900)

Michael Fulmer throws a lot of fastballs and Soler is one of the better fastball hitters around. Just like Pedro Cerrano, straight ball he hit very much. Much like Cerrano, Soler could use some of Jobu's help with the curveball, but that's a pitch that Fulmer rarely throws anyway. Soler's ISO against Fulmer's brand of fastball is .727. The ISO on the slider and sinker are nearly .300. He's the guy that is most likely to get a hold of a Fulmer offering today, according to the metrics.

 

DraftKings DFS Stacks

  • New York Mets vs. Patrick Corbin
  • Minnesota Twins vs. Wil Crowe
  • Sneaky Stack: St. Louis Cardinals vs. Luis Castillo

 



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!




MLB DFS News and Injury Alerts


More DFS Lineup Picks and Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Mike Evans

Wastes No Time Making a Big Impact in Return
Bijan Robinson

Dismantles Buccaneers Defense in Week 15 Upset
Kirk Cousins

Tosses Three Touchdowns in Primetime Victory
Kyle Pitts Sr.

Explodes for Best Outing of Career on TNF
Mike Conley

Unavailable Friday
Dennis Schröder

Dennis Schroder Downgraded to Out Thursday
Anthony Edwards

Iffy to Face Warriors
Davante Adams

Remains Absent From Practice Thursday
Kris Murray

Makes Third Start of the Campaign Thursday
Gary Trent Jr.

Replaces Jericho Sims in Starting Unit Thursday
Jarrett Allen

to Remain Sidelined Friday
AJ Green

Misses Second Consecutive Game
Kyle Pitts Sr.

Officially Active on Thursday Night
Jordan Poole

Cleared for Action Thursday
Ja Morant

Listed as Questionable for Friday's Tilt
Mike Evans

Officially Active on Thursday Night
Miles McBride

to be Re-Evaluated in One Week
Robert Williams III

Yang Hansen Out Thursday
Lauri Markkanen

Available Friday Night
LaMelo Ball

Sidelined for Friday
Tyrese Maxey

Dealing With Illness But Expected to Play Friday
Nique Clifford

to Start Thursday
Kristaps Porzingis

Out of Action Versus Pistons Friday
Joel Embiid

Probable Ahead of Friday's Matchup With Pacers
Ryan Leonard

to Miss 3-4 Weeks
Mats Zuccarello

Lands on Injured Reserve
Timo Meier

Takes Leave of Absence
Draymond Green

Ruled Out for Friday Versus Timberwolves
Thatcher Demko

Back in Canucks Crease Thursday
Josh Norris

Out on Thursday
Boone Jenner

Rejoins Blue Jackets Lineup Thursday
Stephen Curry

Off Injury Report for Friday's Matchup With Minnesota
Victor Hedman

Placed on Injured Reserve
Charlie McAvoy

Set to Return Thursday
Philip Rivers

Colts Prepping Philip Rivers to Start in Week 15?
John Konchar

Will Undergo Thumb Surgery
Zach Edey

Out at Least Four Weeks
CFB

Bryce Underwood Could Leave Michigan Without Buyout
Mike Evans

Expected to Play Thursday, But Only on Key Downs?
Fernando Tatis Jr.

Padres Not Considering Trading Fernando Tatis Jr.
Tarik Skubal

Tigers Engaged in "Serious Talks" Around Trading Tarik Skubal at the Winter Meetings
Josh Jacobs

Calling Himself Day-to-Day
CFB

Chris Brazzell II Declaring for NFL Draft
CeeDee Lamb

on Track to Play on Sunday Night
CFB

Fernando Mendoza Named AP College Football Player of the Year
Raisel Iglesias

to Remain the Braves Closer
Robert Suarez

Agrees on Three-Year Deal With Braves
T.J. Watt

Could Miss Monday's Game With a Lung Issue
Trey Hendrickson

Moved to Injured Reserve
Josh Jacobs

Likely to Miss a Second Straight Practice
De'Von Achane

to Start the Week as Limited in Practice
CFB

Sherrone Moore Remains in Police Custody
CFB

Joe Klanderman Joining Baylor Coaching Staff
Alex DeBrincat

Extends Scoring Streak With Three-Point Effort
Dylan Guenther

Lights the Lamp Twice Wednesday
CFB

Kentucky Hiring Jay Bateman as Next Defensive Coordinator
Sam Bennett

Tallies Three Points Against Mammoth
Vince Dunn

Caps Off Three-Point Performance With Overtime Winner
Spencer Knight

Stops Rangers From Scoring Wednesday
Simon Edvinsson

Makes Early Exit Wednesday
Jared McCann

Injured in Wednesday's Win
Si Woo Kim

Closes 2025 With Strong Finish Among Putting Woes
Akshay Bhatia

Looks to Rebound in 2026 After Down Year Off the Tee
Brian Harman

2025 Season a Step Back Despite Spring Win
Sam Burns

' Elite Putting Headlines a Solid 2025 Season
Sepp Straka

Ends Stellar 2025 Campaign on a High Note
Robert MacIntyre

Closes Out a Steady 2025 Campaign
CFB

Chip Kelly Interviews for Georgia Tech Offensive Coordinator Job
CFB

Louisville Receiver Chris Bell has a Torn ACL
Davante Adams

in Good Spot for Week 15 Despite Hamstring Soreness
Dakota Mermis

to Miss a Month
Jake Evans

to Miss Thursday's Matchup
Elias Pettersson

Unlikely to Play Thursday
Min Woo Lee

Breaks Through to Win in Texas This Year
Nick Bjugstad

to Miss at Least Three Games
PGA

Alex Noren Wins Twice on European Tour This Year
Connor Hellebuyck

Returns to Practice
John Carlson

Could Return Thursday
Wyndham Clark

has Up-and-Down 2025 Golf Season
CFB

Michigan Fires Head Coach Sherrone Moore
Corey Conners

Comes Close to Winning Again in Very Good 2025
Justin Rose

Turns Back the Clock in 2025
Mike Evans

Officially Questionable for Thursday Night Game
Geno Smith

Unlikely to Play in Week 15
CFB

Jim Knowles Expected to be Hired as Tennessee's Defensive Coordinator
Tyrone Tracy Jr.

"Good to Go" for Week 15
Harris English

Enjoys Solid Finish at Hero World Challenge
CeeDee Lamb

has "One or Two" Things Left to the Clear Concussion Protocol
Jayden Daniels

Commanders Not Shutting Down Jayden Daniels for the Year
CFB

Defensive Coordinator Jim Knowles Not Being Retained at Penn State
CFB

Indiana's Stephen Daley Done for Season After Post-Game Injury
Pete Alonso

Orioles Finalizing Five-Year Deal
Kyle Finnegan

Tigers, Kyle Finnegan Agree on Two-Year Deal
Bo Bichette

Red Sox Out on Bo Bichette For Now
Philadelphia Phillies

Phillies Extend Manager Rob Thomson Through 2027 Season
Michael King

the Mets' Top Rotation Target?
Ronald Acuña Jr.

Ronald Acuna Jr. Could Move Back to Leadoff Spot
CFB

Florida, Wisconsin Among Suitors for QB Transfer Kenny Minchey
CFB

Bryan Harsin, Justin Wilcox Candidates for Washington State Head Coach Job?
Edwin Díaz

Edwin Diaz Agrees to Deal With the Dodgers
Kyle Schwarber

Returning to Phillies on Five-Year Deal
CFB

Ole Miss Hiring John David Baker as Offensive Coordinator
CFB

Ty Howle the Top Target for Virginia Tech Offensive Coordinator Job
Shohei Ohtani

to be Used More as Traditional Starting Pitcher Next Year
Yordan Alvarez

to Become Full-Time DH in 2026?
Mason Miller

Padres Plan to Keep Mason Miller in the Bullpen
Ranger Suárez

Orioles Interested in Signing Ranger Suarez
Anthony Volpe

Yankees Don't Expect Anthony Volpe to be Ready in April
Gerrit Cole

Targeting a Return in May/June
CFB

Heisman Trophy Finalists Announced on Monday
CFB

Anthony Hill Jr. Declaring for 2026 NFL Draft
CFB

Ryan Walters a Candidate for Tennessee Defensive Coordinator Job?
Rory McIlroy

Ends 2025 as the Year's Most Unburdened Player
Aaron Rai

Needs to Figure Out Putting Woes This Offseason
Jordan Spieth

Plays Better on Paper in 2025 Than Results Show
PGA

Chris Gotterup Needs to Find Better Touch and Consistency This Offseason
Hideki Matsuyama

Ends 2025 Season With a Bookend Victory
CFB

Tennessee Fires Defensive Coordinator Tim Banks
Scottie Scheffler

Comes Up Just Shy of Hero World Challenge Victory
Merab Dvalishvili

Drops A Decision At UFC 323
Petr Yan

Reclaims Bantamweight Title
Alexandre Pantoja

Era Ends With Gruesome Injury
Joshua Van

Becomes Second-Youngest UFC Champion
Brandon Moreno

Suffers His First TKO Loss
Brandon Moreno

Tatsuro Taira Becomes First Fighter To Finish Brandon Moreno
Henry Cejudo

Payton Talbott Retires Henry Cejudo
Henry Cejudo

Retires After UFC 323 Loss
Jan Blachowicz

Bogdan Guskov Vs. Jan Blachowicz Ends In A Majority Draw
Jan Blachowicz

And Bogdan Guskov Fight To Majority Draw
CFB

Texas RB CJ Baxter Entering Transfer Portal
San Francisco Giants

Jeff Kent Elected to Baseball Hall of Fame
Ketel Marte

Red Sox Interested in Trading for Ketel Marte
Kyle Schwarber

Pirates Make Four-Year Offer to Kyle Schwarber

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP