X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

#1 Expert Projections
Save 50% Now
Import Your Leagues
Props Tool
Compare Any Players
Compare Any Players
24x7 News and Alerts

DraftKings Daily Fantasy Baseball Picks (4/25/21): MLB DFS Lineups

Brandon Woodruff - Fantasy Baseball Rankings, MLB Injury News, DFS Lineup Picks

The top daily fantasy baseball lineup picks for DraftKings on 4/25/21. Euan Leith's MLB DFS analysis and sleepers for building optimal DFS rosters.

We've got a giant main slate with a dozen games starting at 1:05 pm Eastern. The Braves and Diamondbacks have a double dipper in Atlanta, so their game in this set will only go seven innings. In the grand scheme of things that may only cost us one at-bat, but we have seen ownership plummet for these seven inning games. That's a way to gain some leverage.

Rain is going to be a problem in the northeast today. I'll be shocked if Boston plays at all. I'm cutting this slate down to 11 games right now. That one is too risky for me to mess with. They can play in New York if they wait the rain out, but we have teams less willing to do that this year. There is a chance of light snow in Minneapolis. That's not going to be a good game with the cold and wind blowing in anyway. The wind is also blowing in in Wrigley and Cleveland. We do have a nice wind blowing out in Detroit and Atlanta though.

This article will provide you with my daily fantasy baseball lineup picks for DraftKings on 4/25/2021. The lineup will range from some of the elite players to mid-priced options and value plays. You can also check out today's FanDuel MLB DFS lineup picks and read more DFS advice and lineup picks for other sports too. It’s also important to monitor injury news and today's MLB starting lineups. If you have any questions or comments, contact me on Twitter.

Featured Promo! Save 50% on any PGA Premium Pass using discount code MASTERS, this week only! Win more with our DFS and Betting Packages, get expert tools and advice from proven winners including the Lineup Optimizer, Research Station, betting/props cheat sheet and more. GAIN FULL ACCESS HERE

 

DraftKings DFS Starting Pitchers

Brandon Woodruff - MIL at CHC ($9,400)

This will be Woodruff's 11th career start against the Cubs, but he only has one decision against them. Part of it is bullpen issues. Part of it was Woodruff not lasting long in starts, particularly early on in his career. The current Cubs roster is hitting a dismal .147 in 109 at-bats against Woodruff, so it's not a fluke. He has a career 2.95 ERA at Wrigley Field. With the wind blowing in, this looks like an elite spot for Woodruff with the way that he's been pitching this year. Woodruff has sparkling numbers across the board. A big reason for that is he has not allowed a ball hit on the barrel of an opponents bat yet. As you would expect, the hard hit percentage is also way down. I expect a really strong start out of Woodruff here.

Danny Duffy - KC at DET ($8,000)

Duffy has allowed just one earned run in 18 innings so far this year with 19 strikeouts. We have seen flashes of brilliance from Duffy here and there throughout his career. He has always been a highly-touted prospect, but has never really put anything together. There is some reason for optimism this year. Duffy's velocity is up across the board and there is a lot more movement on his four-seamer and curveball. And honestly, this is a dream matchup for Duffy. The Tigers are hitting a dismal .179 against southpaws this year and were completely shut down by fellow lefty Mike Minor on Friday. The Tigers are striking out an alarming 35.9% against lefties this year. Duffy may regress at some point, but it shouldn't start here.

Other Options: John Means ($8,900), Kohei Arihara ($7,000), Michael Kopech ($6,900)

 

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's RealTalkRaph on DraftKings - join in on the winning!

 

DraftKings DFS Infielders

Andrew Knizner - C, STL vs. CIN ($2,200)

Predicting who catches on Sunday afternoons can be a daunting task, but the Cardinals are still without Yadier Molina and Knizner has filled in pretty well for him. The price is low despite Luis Castillo getting absolutely destroyed by the Cardinals on Opening Day, and really not looking good in a start since. Knizner homered off of Castillo in the only game that he has started against him. For this low of a price, it's worth seeing if he can do it again.

Joey Votto - 1B, CIN at STL ($4,400)

Is Votto back? The four homers in a nice touch, but the .225 average leaves something to be desired. His walk rate is also the lowest of his career. Now the good news: The hard hit percentage is by far the best of his career and a .312 xBA suggests that Votto has been a little unlucky so far this year. The launch angle, exit velocity, and hard hit percentage are all at or above his marks during his heyday. Votto is absolutely mashing fastballs this year, which is exactly where Jack Flaherty has been struggling. History is on Votto's side too. He is 6-13 in his career against Flaherty.

Adam Frazier - 2B, PIT at MN ($4,400)

Frazier is firmly entrenched atop this Pirates lineup and has been one of the few bright spots in it thus far. Matt Shoemaker has always been a junkballer, but is has caught up to him in recent years. His 6.28 ERA looks bad, but the xERA of 7.23 suggests that he should be even worse. Opponents have a staggering 17% barrel percentage against Shoemaker so far. Frazier profiles well against Shoemaker's best pitches, the sinker and splitter. The other Frazier (Todd) is the only Pirate that profiles better, but you have to have some stones to run with the Toddfather right now.

J.D. Davis - 3B, NYM vs. WAS ($3,400)

Something is off with Patrick Corbin. His strikeout rate so far is by far the lowest rate of his career. Though the 10.95 ERA is a little bloated, his xERA is still a catastrophic 7.06. If there weren't a good track record attached to Corbin, he wouldn't even be in the majors right now. It's not even a velocity issue for Corbin. His velocity is fine. Hitters just aren't chasing his pitches anymore. His fastball and slider are getting crushed right now. I'll have a few five-man Mets stacks, but they will all start with Davis. Not only does Corbin struggle with right handed power, Davis has a .462 ISO with three homers in 26 career at-bats against Corbin. He may as well be hitting off a tee.

Eugenio Suarez - SS, CIN at STL ($5,300)

Normally I wouldn't go out of my way to run hitters at guys like Luis Castillo and Jack Flaherty, but they are both off this year. Both are suffering about a 1.5 MPH loss on the fastball from last year. What's even more concerning for Flaherty is that he is missing a lot of movement on his slider and fastball. The only thing worse than throwing a pitch slower is not having it move effectively. Suarez homered off of Flaherty on Opening Day, his third off of Jack in just 15 at-bats. This is DFS, people. If we aren't chasing homers, what the hell are we even doing out here?

 

DraftKings DFS Outfielders

Byron Buxton - OF, MN vs. PIT ($5,600)

I have been a Buxton truther since my beloved Twins drafted him and I caught a game that he played for Cedar Rapids back in 2013. His tools have never translated to major league success due to injuries and a free-swinging style that would make Kirby Puckett proud. The difference is that Kirby would swing at damn near everything, but he always made contact. That is what has eluded Buxton until now. His chase rate and K rate are far below his career numbers, even though he still doesn't walk. Buxton has an impossible 30.6 barrel percentage - the best in the majors - and is in the 100th percentile in xwOBA, xBA, xSLG, xISO, and hard hit percentage. Oh, and he's facing a pitcher that has given up 12 runs in nine major league innings. This is yet another smash spot for Buxton. Ride him until he cools off.

Michael Conforto - OF, NYM vs. WAS ($4,100)

Allow me to highlight one of the less obvious pieces of my Mets stack. Yes, I realize that Corbin has handled lefties fairly well in his career. Every lefty but Michael Conforto, that is. Conforto is 9-25 with five homers, 12 RBI, and a .640 ISO. Most will be on the right handed side of this Mets stack, but Conforto may be forgotten since he's a lefty. He is one of the few that has managed to get to Corbin.

Jorge Soler - OF, KC at DET ($3,900)

Michael Fulmer throws a lot of fastballs and Soler is one of the better fastball hitters around. Just like Pedro Cerrano, straight ball he hit very much. Much like Cerrano, Soler could use some of Jobu's help with the curveball, but that's a pitch that Fulmer rarely throws anyway. Soler's ISO against Fulmer's brand of fastball is .727. The ISO on the slider and sinker are nearly .300. He's the guy that is most likely to get a hold of a Fulmer offering today, according to the metrics.

 

DraftKings DFS Stacks

  • New York Mets vs. Patrick Corbin
  • Minnesota Twins vs. Wil Crowe
  • Sneaky Stack: St. Louis Cardinals vs. Luis Castillo

 



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!




MLB DFS News and Injury Alerts


More DFS Lineup Picks and Analysis




POPULAR FANTASY TOOLS

#1 Expert Projections
Save 50% Now
Import Your Leagues
Props Tool
Compare Any Players
Compare Any Players
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Joel Kiviranta

Remains Out of the Lineup Versus Minnesota
Anthony Volpe

Reinstated from Injured List, Optioned to Triple-A
Josh Manson

Out for Game 1 Against Minnesota
Carter Bryant

Iffy for Game 1 Against Timberwolves
Joel Embiid

Considered Probable for Monday
Kyle Anderson

Available for Round 2 Opener
Ayo Dosunmu

Tagged as Questionable on Injury Report
Anthony Edwards

Listed as Questionable for Game 1 Against Spurs
Luka Dončić

Luka Doncic Unavailable for Start of Round 2, Considered Week-to-Week
Brandon Ingram

Won't Play in Game 7 Against Cavaliers
Ranger Suarez

Exits Sunday's Start with Hamstring Tightness
Agustín Ramírez

Marlins Demote Agustin Ramirez to Triple-A
Victor Hedman

Will Not Play Sunday Versus Montreal
Noah Dobson

Will Play Against Tampa Bay on Sunday
Marvin Mims Jr.

Path to Dynasty Relevance May Require a Change in Scenery
Tank Bigsby

Remains a High-End Dynasty Handcuff Running Back in Philadelphia
Ben Rice

Exits Sunday's Contest with Left Hand Contusion
Hunter Henry

Long-Term Future in New England in Question After NFL Draft?
Matthew Golden

a Prime Dynasty Buy-Low Candidate Heading into 2026
Kevin Huerter

is Out for Game 7
Jalen Coker

Carries Breakout Potential into 2026
Dak Prescott

Remains a Dynasty QB1 Heading into 2026
Nikola Vučević

Nikola Vucevic Could be Done in Boston
Christopher Bell

Is Christopher Bell Worth Rostering for Texas Lineups?
Cal Raleigh

Considered Day-to-Day With Soreness in his Side
Brandon Ingram

is Downgraded to Doubtful for Game 7
William Byron

Might have the Speed to Compete for the Win at Texas
Jonathan Isaac

Remains Out for Game 7
Joey Logano

Provides Solid Upside for Texas DFS Lineups
Joe Ryan

Exits Early From Start on Sunday Due to Elbow Soreness
Chase Briscoe

Could Chase Briscoe be A Sneaky Pick for Texas Lineups?
Ty Gibbs

Should DFS Managers Roster Ty Gibbs at Texas?
Daniel Suarez

Is Daniel Suarez Worth Rostering After Career-Best Starting Position at Texas?
Daniel Palencia

Cubs Reinstate Daniel Palencia From the Injured List on Sunday
Kyle Busch

Is a DFS Risk Starting in the Top 10 at Texas
Ronald Acuña Jr.

Braves Place Ronald Acuna Jr. on Injured List With Strained Hamstring
Nick Lodolo

Expected to Make Season Debut on Friday
Tyler Reddick

One of the Favorites to Win Texas
Chase Elliott

Could Contend for Another Win at Texas
Carson Hocevar

on Pole at Texas
NASCAR

Bubba Wallace Wrecks in Practice at Texas
Chris Buescher

Looking to Continue Strong Run at Texas
Austin Dillon

Blows Engine in Practice at Texas
CeeDee Lamb

Is CeeDee Lamb Being Undervalued?
Bijan Robinson

Could Just Be Entering His Dynasty Prime
Derrick White

Delivers All-Around Line in Game 7 Loss
Neemias Queta

Finishes with Double-Double in Playoff Loss
Malik Washington

Emerging as a Low-Cost Dynasty Buy Out of Ambiguous Receiver Room
Jaylen Brown

Posts Strong Line but Celtics Fall Short
Diego Pavia

Ravens Noncommital on Diego Pavia's Future with Team
Tyrese Maxey

Dominates in Series-Clinching Victory
David Njoku

Visiting the Chargers on Monday
VJ Edgecombe

Provides Key Spark in Game 7 Win
Patrick Mahomes

Expected to Participate in OTAs
Joel Embiid

Delivers 34 Points in Series Clincher
Ayo Dosunmu

Considered Day-to-Day Ahead of Game 1
Mike Reilly

Delivers Two Assists in Game 1 Win
Logan Stankoven

Establishes New Franchise Record With Five-Game Goal Streak
Frederik Andersen

Records Second Postseason Shutout
Radko Gudas

Ducks Hope to See Radko Gudas Return During Second Round
Josh Manson

Day-to-Day Ahead of Game 1 Against Wild
Joel Kiviranta

Considered Day-to-Day
Joel Eriksson Ek

Questionable for Game 1 Against Avalanche
Cal Raleigh

Scratched From Lineup, No Reason Given
Ronald Acuña Jr.

Ronald Acuna Jr. Exits with Left Hamstring Tightness
Anthony Edwards

Remains Week-to-Week
Joel Embiid

Available for Game 7 Against Celtics
Paul George

Cleared to Play Saturday
Owen Tippett

Unlikely to Play Saturday
Jonas Brodin

to Miss Game 1 Against Avalanche
Nikita Zadorov

Played Through Torn MCL in Playoffs
Connor McDavid

Played With Fractured Foot Against Ducks
Alexander Nikishin

a Game-Time Call Saturday
Nikolaj Ehlers

Expected to Play Saturday
Greg Dulcich

Carries Breakout Potential into 2026
Kaelon Black

Well-Positioned for Dynasty Success Following NFL Draft
J'Mari Taylor

Can J'Mari Taylor Break Through Crowded Running Back Depth Chart in Jacksonville?
Eli Raridon

Dynasty Stock Rising Following NFL Draft
Michael Trigg

Facing Uphill Battle for a Roster Spot in Dallas
Matthew Hibner

Is Matthew Hibner the Tight End of the Future in Baltimore?
Seth McGowan

Likely to be RB3 to Begin his Rookie Season
Caleb Douglas

a Low-Upside Dynasty Stash Competing for a Role in Miami
Francis Mauigoa

Giants "Comfortable" With Francis Mauigoa's Back
Yandy Díaz

Yandy Diaz Leaves With Side Tightness, Considered Day-to-Day
Jacob Misiorowski

Leaves Start Early on Friday With Hamstring Cramp
Brandon Nimmo

Aggravates Hamstring, Pulled Early on Friday
Ryan Helsley

Placed on Injured List With Elbow Inflammation
Dylan Holloway

Signs Five-Year Extension With Blues
Barrett Hayton

Jack McBain Iffy for Friday
Logan Stanley

a Game-Time Decision Friday
Viktor Arvidsson

Ruled Out Friday
Ryan Pepiot

to Miss the Rest of the Season, Scheduled for Hip Surgery
Brandon Woodruff

Goes on Injured List With Shoulder Inflammation
Nico Hoerner

Leaves Friday's Game Early With Neck Tightness
Jack Della Maddalena

Returns At UFC Perth
Carlos Prates

Set For UFC Perth Main Event
Quillan Salkilld

Set For Co-Main Event
Beneil Dariush

An Underdog At UFC Perth
Steve Erceg

Looks To Win Back-To-Back Fights
Tim Elliott

Looks For His Third Consecutive Win
Ollie Schmid

Set For His UFC Debut
Marwan Rahiki

Looks To Remain Undefeated
Wyatt Langford

Suffers Setback With Forearm Injury
Brandon Woodruff

to Get Some Time Off
Michael Harris II

Could be Forced to the Injured List
Gary Woodland

Riding Momentum Into Cadillac Championship
Jordan Spieth

Brings Boom-or-Bust Potential to Cadillac Championship
Adam Scott

Looks Poised for Another Strong Finish at Doral
Maverick McNealy

Needs Approach Game to Click at Doral
CFB

Jameson Williams Files Lawsuit Against NCAA, SEC, Big Ten
Harry Hall

Volatility Continues at Cadillac Championship
Tommy Fleetwood

Looks to Rebound at Trump National Doral
Pierceson Coody

a Risky Value Play at Cadillac Championship
Akshay Bhatia

Offers Upside with Risk at Cadillac Championship
Justin Thomas

a Scary Proposition at Cadillac Championship
Scottie Scheffler

The Leading Favorite at Cadillac Championship
Collin Morikawa

Still a Smash Play at Cadillac Championship
Viktor Hovland

Showed at Augusta He Can Finish Well
Sepp Straka

Attempting to Finish Better in Miami
PGA

J.J Spaun Enduring Roller Coaster Start to 2026
Min Woo Lee

Seeks to Make Adjustments at Cadillac Championship
Max Homa

May Struggle at Old Doral This Weekend
Ben Griffin

Rebounds From Rough Stretch as Miami Looms
Shane Lowry

Searching For Answers at Cadillac Championship
Russell Henley

Daunting Test at Doral Likely Not a Place For Russell Henley
Justin Rose

Returns to Action After Finishing Third at Masters Tournament
Hideki Matsuyama

Has The Approach Game to Win at Cadillac Championship
CFB

Brendan Sorsby Facing Potential Permanent Loss of Eligibility
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF