👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

Week 6 NFL Matchups Analysis: Start/Sit for Fantasy Football (Part 3)

By Sgt. Alexander Martinez (15th Wing) [Public domain], via Wikimedia CommonsWelcome to Week 6 of NFL and fantasy football action, RotoBallers. Each week of the NFL season, we will be breaking down each of the NFL matchups and providing you with some fantasy football advice and lineup recommendations based on matchups that we love, matchups that we hate, and some high-risk/high-reward players, as well.

Below, you will find part 3 of our Week 6 NFL matchups & fantasy football start/sit analysis, which should help you prepare your lineups to win this week. It’s essential to analyze the weekly NFL matchups to find lineup sleepers and gems, while also avoiding those players who may turn out to be busts.

To read about the rest of this week’s NFL matchups, check out Start/Sit &  Matchups Analysis for Games 1-7, Start/Sit & Matchups Analysis for Games 8-11, and our Week 6 Standard and PPR Rankings. And of course you can always stop by the RotoBaller chat rooms for any live advice you may need

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Cowboys @ Seahawks - Sunday 10/12 @ 4:25 EST

Matchups We Love

Demarco Murray: Yes it's a tough defense, but Seattle can give up points to running backs especially in a PPR format. Don't let the matchup scare you away from Murray this week.

Marshawn Lynch: The Cowboys defense is vulnerable, and has given up 5.72 yards per carry this season to opposing running backs. Arian Foster shredded them last week, and Beast Mode will probably have a big game too.

Russell WilsonThis man is a beast, both in the NFL and in fantasy football. He's one of the truly elite NFL quarterbacks, and is a must start QB1 every week. It's possible that Seattle will run the ball relentlessly, but Wilson should still get his passing attempts, rushing yards and touchdowns.

Matchups We Hate

Tony RomoI will let the matchup scare me away from Romo. It's a loud building, Seattle has a terrific secondary, plus a Romo is a quarterback that has a knack for making mistakes. Romo might have a solid game, but if you have another solid QB option consider starting them instead.
 
High Risk/High Reward

Seattle DST: I like what the Cowboys are doing offensively, and wouldn't be shocked if they put up some points this week. I also wouldn't be shocked if the Seattle defense dominated here. Start 'em, but this is not a lock by any means.

Notable Matchups

Cowboys Wide Receivers: It's nearly impossible to ever sit Dez Bryant, especially in PPR leagues, even going up against a tough Seattle secondary. Don't think about this too much and get him in your lineups. Terrance Williams has a lot of points and touchdowns, but the targets aren't really overwhelming. He's a risky start this week. Jason Witten is a riskier start also for standard leagues, and a decent but not spectacular play in PPR leagues. He just isn't producing so far.

 

Redskins @ Cardinals - Sunday 10/12 @ 4:25 EST

Matchups We Love

Andre EllingtonAnother week with banged up quarterbacks means another week of leaning on Ellington for Arizona. He'll get to face a defense that just got ran all over by Russell Wilson. Consider him a must start, especially in PPR leagues.

Matchups We Hate

Larry Fitzgerald and Michael Floyd: Both of these guys have been disappointing so far this year, and it's hard to trust them right now, at least until Carson Palmer comes back. They are flex plays at best, even in this favorable matchup.

High Risk/High Reward

Cardinals DST: The Arizona defense is legit, and while this may look like a favorable matchup on paper, the Redskins can score plenty of points. I'd use them, but just like with Seattle, there's potential for disappointment here.

Kirk CousinsHe has a pretty good matchup on paper and played well last week. Arizona gives up more yards in the air than on the ground, and their secondary isn't nearly as good as their run defense. I can see Cousins throwing for a bunch of yards and a couple of touchdowns here.

DeSean Jackson and Pierre GarconJackson has been playing well and is going up against a secondary that he might be able to burn. He's still a bit boom-or-busty, but I'd start him with a fair amount of confidence. Garcon is a mess right now, and isn't getting nearly enough targets (3, 6, 16, 4 over the past four weeks). At this point he's essentially a boom-or-bust wide receiver week to week, but is an acceptable gamble in PPR leagues. If you have other consistent WR options, consider starting them instead.

Notable Matchups

Arizona Quarterbacks: If Carson Palmer plays, it changes the entire Arizona offense and elevates the potential for their wide receivers. If they don't, and either Drew Stanton or Logan Thomas plays, I would avoid this situation for your fantasy teams.

Jordan ReedReed is expected back this week, and is always a solid fantasy tight end when healthy. This is a tricky situation though since he's been off the field for a while, and Niles Paul is still in the picture. Arizona gives up a lot of points to tight ends, so start Reed if you need to. But this may be a week to watch and analyze (rather than start either player), and start a different TE if you have another viable option.

 

Giants @ Eagles - Sunday 10/12 @ 8:30 EST

Matchups We Love

Andre Williams: There's a lot of potential here, and there will be plenty of touches for Williams this week in what should be a high scoring affair. I'd consider Williams a solid RB start this week, as he should carry the load and looked good last week filling in for Rashad Jennings.

Jeremy MaclinMaclin is an every week start and WR1. He is leading the NFL in targets and has been a fantasy football monster.

Matchups We Hate

LeSean McCoyBecause of where you drafted him, you almost have to start McCoy, but even in his monster 2013 season, the Giants were able to hold him to a combined 95 yards on 38 carries and a score in two games. His already disappointing season may continue this week.

Zach ErtzHe is pretty much a TE2 at this point. His production just isn't there, he's been inconsistent, his playing time has been decreasing and the Giants give up the least amount of points to tight ends. Avoid him unless you have no other options this week.

High Risk/ High Reward

Eli Manning: Any time you use Eli, it's a gamble, but he seems to finally be adjusting to his new offensive scheme. He also has a good matchup in what should be a high scoring game. He makes for a solid bye week fill in, and could have a monster day for you. He also could throw three picks, but I like his chances overall.

Notable Matchups

Giants Wide Receivers: Rueben Randle has 10 targets in each of the last three games, and Eli Manning has already stated that he wants to get him the ball as much as he can. Victor Cruz is seeing targets, but has been inconsistent week to week. He's settled into a high-upside WR3/flex option at this point. Odell Beckham looked good in his first ever NFL game last week, and should only see more playing time and targets going forward. He's a decent WR3/flex going forward, especially in PPR leagues, as the Giants base offense runs three-wide receiver sets.

Darren SprolesSproles is essentially a flex play for PPR leagues these days, although the upside is always there. He just isn't getting a consistently high volume of snaps and touches, making him an unreliable fantasy option.

Larry DonnellAlthough Donnell was shut out last week, that will most likely be an outlier for his season. He's still a red zone focus for Eli Manning, and with so many offensive weapons defenses won't be able to focus on shutting him down like they did last week.

 

49ers @ Rams - Monday 10/13 @ 8:30 EST

Matchups We Love

Frank GoreFrank the Tank has been running well all season, and doesn't seem to be slowing down. He has a tasty matchup on paper against the Rams rushing defense, and the 49ers should bring their running attack as the focus of their offensive game plan.

Matchups We Hate

Zac Stacy and Benny Cunningham: Zac Stacy is working through an injury that forced him to leave last week's game, and is facing an extremely tough 49er rushing defense. If he doesn't end up suiting up, then Cunningham would step into the lead running back role for the Rams. Either way this is a week to avoid the Rams running backs unless you have no other choice.

Vernon DavisDavis has been battling injuries for a lot of the season, but it's looking like he will suit up this week against the Rams. That's the good news. The bad news is that the Rams have been very good against tight ends since last year, so it's a risky week to start him. He may have a big game, or he may end up leaving with another injury. Given he's playing Monday night, there's added risk, so if you have another TE option consider starting them instead.

High Risk/High Reward

Colin KaepernickKaepernick has been playing well for the most part this year, but this is a game where the 49ers may end up running the ball all day. He should be a fine start, but may not have as big a ceiling as other weeks.

Michael CrabtreeHe had a bad game last week, but is the primary passing for Kaepernick always. He's a high-upside WR3 at worst every week in PPR leagues, and the matchup is a good one this week. He should get targets and receptions, but may not have a high ceiling either.

Notable Matchups

Brian QuickQuick has been a legit breakout and fantasy football stud this year, especially in PPR leagues. He had a monster game last week and has been a target and receptions hog for the Rams. The 49ers secondary is vulnerable, so Quick may be in line for another productive day. I wouldn't expect two touchdowns, or even one necessarily, but a handful of receptions and yards should be his floor.

Austin DavisThe 49ers have been limiting the production of opposing quarterbacks the past few weeks, and the same could happen again this week. Davis may have a decent game, but may also be in for a long day at the office. I'd avoid him unless it's a two-quarterback league.

Anquan BoldinBoldin hasn't really been a great fantasy option week to week. In PPR leagues, he's racked up 9.20, 8.70, 6.60 and 4.40 points over the past four weeks. He'll get a few grabs every week, but doesn't really offer much upside. Only start him if you don't have any better options.

 




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Cole Caufield

Ends Dry Spell Sunday
Alex Newhook

Nets Two More Goals in Sunday's Victory
Mitchell Marner

Notches Three Assists in Losing Effort
Beckett Sennecke

Extends Goal Streak to Three Games
Cutter Gauthier

Records Hat Trick of Assists in Game 4 Win
Ashton Jeanty

a Top-Five Dynasty RB Despite Disappointing Rookie Campaign
Devin Neal

the Potential RB2 in New Orleans in his Sophomore Season
Ricky Pearsall

Does Ricky Pearsall Still Have Breakout Potential for Fantasy Managers?
Tory Horton

Dynasty Stock on the Decline Despite Big-Play Ability
Tank Dell

Improving, But Not 100 Percent Yet
Karl-Anthony Towns

Logs Sixth Double-Double of Postseason
Mike Conley

Ayo Dosunmu Replaces Mike Conley in Starting Unit Sunday
Miles McBride

Tallies Game-High 25 Points in Series-Clincher
Tyrese Maxey

Settles for 17 Points Sunday
Joel Embiid

Scores Efficient 24 Points in Season-Ending Loss
Caris LeVert

Iffy for Monday Night
Kevin Huerter

Listed as Questionable for Game 4
Auston Matthews

Uncertain About Future With Maple Leafs
Frederik Andersen

Enjoying Special Postseason
Josh Manson

"Close" to Returning
Joel Kiviranta

Could Return to Action Monday
Radko Gudas

a Game-Time Call Sunday
Mark Stone

Unavailable Sunday
Sean Tucker

Dynasty Upside Remains Limited by Crowded Backfield Picture
Puka Nacua

Is Puka Nacua's Dynasty Value Impacted by Potential Off-Field Concerns?
Alec Pierce

Can Alec Pierce Build on Encouraging 2025 Production in 2026 and Beyond?
Keenan Allen

Dynasty Stock Falling with NFL Future in Limbo
Drake London

Remains a Dynasty WR1 Entering 2026
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Bucky Irving

Potentially Undervalued After Disappointing Sophomore Season
Austin Reaves

Nears Double-Double In Game 3 Loss
Davante Adams

a Dynasty Hold Who Could See His Value Slip
LeBron James

Facing Sweep With Game 4 on Monday
Emeka Egbuka

The Pendulum Swinging Back on Emeka Egbuka's Dynasty Value
Ajay Mitchell

Posts Career Playoff Night in Game 3
Chet Holmgren

Helps Thunder Move to Brink of Conference Finals
Michael Pittman Jr.

Undervalued in an Environment Fit for His Skill Set
Tobias Harris

Extends 20-Point Streak in Saturday's Loss
Evan Mobley

Keeps Defensive Production Rolling Saturday
Rhamondre Stevenson

a Quality Dynasty Target in a Still-Improving Offense
Golden State Warriors

Warriors Extend Steve Kerr into his 13th Season
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Odell Beckham Jr.

Giants Not Looking to Sign Odell Beckham Jr. Right Now
Bo Nix

Will be Full Speed Before Training Camp
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
Joey Logano

Needs a Good Run at Watkins Glen
Luis Castillo

Mariners Intend to Piggyback Luis Castillo, Bryce Miller
Duncan Robinson

Shines on Both Ends Saturday
Cade Cunningham

Records Second Career Postseason Triple-Double
Donovan Mitchell

Logs 35-Point Double-Double
James Harden

Plays Late Hero Saturday
OG Anunoby

Could Miss Another Game Sunday
Joel Embiid

Considered Probable for Sunday's Elimination Game
Jarred Vanderbilt

Active on Saturday Night
Logan Webb

Placed on 15-Day Injured List With Knee Bursitis
Bryce Miller

is Set to Return on Wednesday
Jeff Hoffman

Could Return to Closer Role
CHI

Blackhawks Bring in Roman Kantserov for Next Season
Mason McTavish

Set to Rejoin Ducks Lineup Sunday
Lukas Dostal

to Remain in Ducks Crease Sunday
Zach Bogosian

Back for Wild Saturday
Jesper Wallstedt

Starting Game 3 Against Avalanche
Joel Eriksson Ek

Not Ready to Return Saturday
Owen Tippett

Won't Play Saturday
Cooper Kupp

a Dynasty Hold into the Start of 2026 Season
Jaylen Warren

a Safe Dynasty Depth Piece with Insurance Upside
Christian McCaffrey

a Risky Dynasty Hold Who Still Exceeds His Trade Value
Brian Thomas Jr.

A Risky Buy-Low with Immense Upside
Taj Bradley

Hits the Injured List With Pectoral Inflammation
Kyle Bradish

has Nice Bounce-Back Performance With 10 K's
Casey Mize

Throws Bullpen on Friday, Return Not Imminent
Ronald Acuña Jr.

Ronald Acuna Jr. Optimistic About Returning Next Wednesday
Mike Matheson

Leads by Example in Game 2 Win
Jakub Dobes

Rebounds After Loss Yet Again for Montreal
Alex Newhook

Sets Tone in Big Montreal Victory
Tyler Glasnow

Dodgers Put Tyler Glasnow on Injured List With Back Spasms
Blake Snell

to Make Season Debut for Dodgers on Saturday
Cole Ragans

Royals Place Cole Ragans on Injured List With Elbow Impingement
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
Nick Lodolo

Officially Activated, Making Season Debut on Friday
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
CFB

Rasheem Biles an Instant Impact Player for Texas
Roman Anthony

Heading for the Injured List
CFB

Sam Leavitt Expected to Be Full-Go for Fall Camp
Tarik Skubal

Could Return in 4-6 Weeks After Successful Elbow Surgery
Cole Ragans

Royals Hopeful That Cole Ragans Makes his Next Start
Emilio Pagán

Emilio Pagan has Grade 2 Hamstring Strain, Expected to Miss 4-8 Weeks
Joe Ryan

Listed as Scheduled Starter for Saturday Against Cleveland
Tyler Glasnow

Not Expected to Land on the Injured List
Framber Valdez

Suspension Reduced to Five Games
Framber Valdez

Suspended Six Games
CFB

Brauntae Johnson the Next Star in Notre Dame's Secondary?
CFB

Ethan Barbour a Name to Know in Georgia's Tight End Room
CFB

Payton Pierce Next Up at Linebacker for Ohio State
CFB

Javin Gordon to Play Significant Role for Tennessee?
CFB

Tanook Hines Stepping into WR1 Role for USC
CFB

Rueben Owens II has "Star Potential" in Fourth Campaign
Collin Morikawa

Withdraws From Truist Championship
Xander Schauffele

Carries Elite Form Into Quail Hollow
Hideki Matsuyama

Looks to Bounce Back at Truist Championship
Matt Fitzpatrick

Secures Third Win of 2026 Season
Patrick Cantlay

Continues Playing Well Heading to Truist Championship
Ludvig Aberg

Returns to Action For Truist Championship
Justin Thomas

Searching for Consistency at Quail Hollow
Jordan Spieth

Looks to Break Through at Quail Hollow
Adam Scott

Brings Strong Form to Quail Hollow
Robert MacIntyre

a Steady Option at Truist Championship
Jason Day

Looks to Overcome Approach Struggles at Quail Hollow
Akshay Bhatia

Looks for Complete Game at Truist Championship
Justin Rose

to Continue Mid-Season Club Change at Truist Championship
Si Woo Kim

is Back to Peak Form Ahead of Truist Championship
Sam Burns

to Bounce Back at Truist Championship
Cameron Young

Looks to Carry Dominance to Quail Hollow
Rory McIlroy

Returns to Familiar Stomping Grounds This Week at Quail Hollow
Chris Gotterup

Looking to Bounce Back at Quail Hollow
Tommy Fleetwood

Looking For Better Iron Play at Quail Hollow
CFB

Mario Craver Enters No. 1 Wide Receiver Role for Marcel Reed
CFB

LaNorris Sellers a Strong Rebound Candidate in 2026
CFB

Cam Coleman Poised for Monster Year at Texas?
CFB

Will Hammond Pushing to Be Ready for Week 1
Alex Fitzpatrick

Looking to Keep Up Ball-Striking Output at Quail Hollow
CFB

Notre Dame Leads College Football in Returning Snaps
CFB

Two Ole Miss Football Players Arrested, Charged with DUI
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF