Kyle's favorite WR vs. CB matchups to exploit for Week 8 of 2025 - DFS wide receivers to target on DraftKings and FanDuel. These WR/CB matchups are GPP and cash game opportunities.
Welcome to the Wide Receiver Matchups to Target column for Week 8 of the 2025 NFL season. With seven games of data to work with, we can now lean on individual performance, matchup grades, pace of play, and implied totals to pinpoint the best WRs to target in daily fantasy lineups. Week 7 was another mixed bag as Rashee Rice, Chris Olave, Romeo Doubs, and George Pickens exceeded value, while Justin Jefferson, Rome Odunze, and Cee'Dee Lamb had challenging games.
This week, we'll break down the top five WR/CB matchups using Pro Football Focus (PFF) grades, along with key usage metrics that indicate which players can realistically hit three times their DraftKings salary. This is meant to serve as a guide for both cash games and GPPs -- these guys are in position to smash regardless of the contest type you're playing in.
Be sure to jump into our RotoBaller Discord! We have so many different channels devoted to whatever you're playing in fantasy football. We also have lots of great NFL DFS articles and NFL DFS tools to help you win MORE this season! Below are my top five WR vs. CB matchups for this week’s DFS main slate. Use these insights to fine-tune season-long lineups, player props, and DFS builds. Let’s get to it!
Ja'Marr Chase, Cincinnati Bengals
- $8.1K on DraftKings, $9.6K on FanDuel
- Vs. Jarvis Brownlee Jr. (New York Jets)
Chase is putting up video game numbers right now, so we're going to want exposure in Week 8. He's averaging 32.7 DK PPG over his last three contests, catching 32-of-45 targets for 365 yards and four touchdowns. He already posted a slate-winning 39.5 DK point total in Week 2, and there’s no reason to believe he won’t continue seeing massive volume against an exploitable Jets secondary.
At 25, Ja’Marr Chase is putting up all-time numbers 🐅🔥 pic.twitter.com/afFqYBmbse
— NFL on CBS 🏈 (@NFLonCBS) October 13, 2025
New York ranks 31st in pass DVOA, 29th in DVOA vs. WR1s, and 26th in PFF's coverage grade. They just gave up 24.2 DK points to Xavier Legette, and Chase is in another stratosphere talent-wise. His individual matchups against Jarvis Brownlee Jr. (24th of 110 CBs) and Brandon Stephens (20th of 110 CBs) don't stand out, but this defense has consistently been beaten through the air. Joe Flacco will keep funneling looks to his superstar, and Chase is again the favorite to lead all receivers in fantasy scoring this week. He's a no-brainer pick in all DFS formats, and probably a player we should be targeting heavily in the prop market as well.
Drake London, Atlanta Falcons
- $6.4K on DraftKings, $7.8K on FanDuel
- Vs. Jack Jones (Miami Dolphins)
London’s season has been a rollercoaster as the Falcons’ offense searches for rhythm, but he flashed massive upside with 28.0 and 34.8 DK point games before a quiet Week 7 versus the 49ers. His usage, though, is elite: 6th in targets (10.5 per game), 4th in target share (31.8%), 8th in receptions (6.3), and 1st in first-read targets (8.7). He gets a dream bounce-back spot in Week 8 against a struggling Miami defense.
Miami ranks dead last in pass DVOA, 21st in DVOA vs. WR1s, and 30th in both PFF's coverage and overall defense grades. London will line up primarily against 5'11" Jack Jones (101st of 110 CBs), who's unlikely to handle his size or route running. The only concern is volume — Miami’s opponents often abandon the pass as the game script dictates - but this is still a ceiling spot worth betting on for tournament builds.
Chris Olave, New Orleans Saints
- $5.8K on DraftKings, $6.6K on FanDuel
- Vs. Jacob Parish (Tampa Bay Buccaneers)
The 'Chris Olave PPR Scam' rolls into Week 8, and he's in position to deliver results for us again. The Saints' go-to receiver has had an excellent season, posting at least 10 DK points in all seven games while ranking as WR16 to this point. He's trending up recently, too, with 15.8 DK points (Week 6) and 26.8 DK points (Week 7) registering as his two highest DFS totals of the year. His price has crept up a bit, but a favorable matchup and likely negative game script should allow him to hit value for us again this week.
Chris Olave this season:
⚜️ 68 Targets (2nd in NFL)
⚜️ 47 Catchable Targets pic.twitter.com/mSuDeqFxa8— PFF Fantasy (@PFF_Fantasy) October 21, 2025
The Saints enter as 4.5-point home underdogs against the Buccaneers, who rank 19th in pass DVOA and allow the fourth-most yards per game to WR1s (79.7). Olave sits 2nd in targets (10.1/game), 7th in target share (31%), and 5th in red zone target share (31%), so he should be able to take advantage of this secondary. Tampa Bay blitzes at the fourth-highest rate in the league, which plays directly to Olave’s strengths as a quick-separation route runner. He looks to be in line for another high-floor, high-volume performance in Week 8.
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Zay Flowers, Baltimore Ravens
- $5.4K on DraftKings, $7.1K on FanDuel
- Vs. Nick McCloud (Chicago Bears)
Flowers has been quiet since his Week 1 explosion (31.1 DK points), failing to top 15 DK points in any game since. A mix of tough matchups (CLE, DET, LAR) and shaky quarterback play with Cooper Rush under center has stunted his production. With Lamar Jackson expected back in Week 8, Flowers gets a prime opportunity to rebound against a beatable and banged-up Bears secondary that's missing its top three cornerbacks (Kyler Gordon, Tyrique Stevenson, and Jaylon Johnson).
Even on a struggling Baltimore Ravens offense, Zay Flowers has a career-best yard per route run rate so far in Year 3.
With Lamar Jackson at QB in 2025:
- 10.6% first down per route run rate (WR14)
- 2.51 yards per route run (WR5) pic.twitter.com/Vx6v7zZGiP— Jacob Gibbs (@jagibbs_23) October 20, 2025
Chicago ranks 20th in pass DVOA and has allowed the ninth-most fantasy points per game to WRs, along with 10 touchdowns to the position - tied for third-most in the NFL. Nick McCloud (72nd of 110 CBs) and Nahshon Wright (53rd of 110 CBs) are overmatched against Flowers, who still boasts strong underlying metrics: a 29.1% target share, 204 yards after catch, and 2.40 yards per route run. Everything points to a bounce-back performance here while his DFS salary remains a bargain. He's going to be among the most popular plays on the slate as he's currently projected for 25% ownership on DraftKings, but we can eat the chalk and make our lineups unique in other spots.
Note: Flowers shouldn't be among your most exposed WRs if Lamar Jackson is ruled out. If Tyler Huntley or Cooper Rush are starting, reserve Flowers for large-field GPPs only.
Michael Pittman Jr., Indianapolis Colts
- $5.6K on DraftKings, $6.8K on FanDuel
- Vs. Jalyn Armour-Davis (Tennessee Titans)
Pittman Jr. produced a solid 19.3 DK points against the Titans back in Week 3, catching all six targets for 73 yards and a touchdown. He’s once again positioned to deliver, operating as the clear WR1 for the league’s highest-scoring offense. His 22.2% target share isn’t elite, but consistent volume, red-zone usage, and touchdown equity keep him firmly in play for DFS contests.
Tennessee ranks 25th in pass DVOA and 30th in DVOA vs. WR1s, continuing a trend of getting shredded by primary receivers. Pittman should see plenty of Jalyn Armour-Davis (79th of 110 CBs), who’s allowed a 75% catch rate and 143 receiving yards in five games. He’ll also get looks against Darrell Baker Jr. (unranked), who’s given up a 100% catch rate, 77 yards, and a touchdown in limited snaps. Even as heavy 14.5-point home favorites, Pittman carries both a strong floor and multi-touchdown upside in this spot. He profiles as an excellent tournament option as he is currently projected for just 4% ownership on DraftKings.
Thanks for reading, and good luck with your DFS contests!
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