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Fantasy football start em, sit em SNF lineups advice for Falcons vs. 49ers on Sunday Night Football in Week 7 (2025). NFL matchups analysis and SNF starts/sits.
We close out the Week 7 Sunday slate with an interesting matchup between two quality teams, as the Atlanta Falcons head to California to take on the San Francisco 49ers.
Atlanta comes in off their most impressive win of the season - a 24-14 victory over the Bills on Monday Night Football. For the Niners, injuries remain the big story, with star tight end George Kittle expected to return in Week 7, but several other key players remaining banged up.
We will bring you Sunday Night Football analysis all season, focusing on who to start, who is on the fence, and who should find the bench. Let's dive into this SNF matchup for Week 7 of the season. Good luck in 2025 fantasy football, RotoBallers!
Be sure to check all of our fantasy football rankings for 2025:- 2025 fantasy football rankings
- Running back (RB) rankings
- Wide receiver (WR) rankings
- Tight end (TE) rankings
- Quarterback (QB) rankings
- FLEX rankings
- Defense (D/ST) rankings
- Kicker (K) rankings
- Dynasty rankings
Atlanta Falcons at San Francisco 49ers
Sunday October 19, 8:20 PM ET
Notable Fantasy Injuries:
- George Kittle - Expected to Play (Hamstring)
- Brock Purdy - Out (Toe)
- Ricky Pearsall - Out (Knee)
- Brandon Aiyuk - Out (PUP)
- Darnell Mooney - Questionable (Hamstring)
Matchups We Love
None
Matchups We Hate
QB Mac Jones
With Brock Purdy again sidelined, it will be Mac Jones - who has battled some injuries himself - under center for the Niners in Week 7. Jones will be more of a QB2 option in Superflex formats. The Falcons haven’t allowed a top-12 QB fantasy finish since Week 1. So, it’s best to avoid all 49ers QBs.
49ers ruled out QB Brock Purdy (toe) and WR Ricky Pearsall (knee) for Sunday night’s game against the Falcons.
49ers QB Mac Jones starts again.
— Adam Schefter (@AdamSchefter) October 17, 2025
Kendrick Bourne has definitely earned more opportunities moving forward. He has totaled over 140 receiving yards in each of the last two games, and Ricky Pearsall will miss his third straight contest. Unfortunately, this is a tougher matchup for Bourne on the outside. A.J. Terrell will likely be matched up against him for most of the game, making Bourne more of a WR4.
George Kittle will return from his hamstring injury this week. His return is certainly going to be a big boost for your fantasy team. However, this isn’t the best matchup for him. The Falcons have allowed the fewest fantasy points to opposing TEs and have yet to allow a TE to finish as a top-20 option. Still, Kittle will be a solid TE1 this weekend.
Kyle Shanahan on George Kittle’s playing time against the Falcons on SNF:
“No pitch count. George has rehabbed really well. Came back 100% and had a good week of practice. We’ll space it out throughout the game, but no pitch count.” pic.twitter.com/RTx4zclKrP
— Coach Yac 🗣 (@Coach_Yac) October 17, 2025
Other Notable Matchups
It’s going to be tough to trust Michael Penix Jr. as a QB1 option this week. He has finished as a top-12 QB just once and has thrown just three passing touchdowns since Week 2. Although the 49ers have let up a top-12 QB finish in back-to-back games, Penix is more of a middle-of-the-pack QB2 play in Superflex formats.
The Falcons have done a great job against RBs in fantasy this year. They have allowed the second-fewest fantasy points per game and the third-fewest receptions per game to opposing RBs across the first six weeks. None of that matters, though, when it comes to Christian McCaffrey. McCaffrey will be an RB1 option this week.
Bijan Robinson will enter the week as an RB1 in fantasy. He has finished as a top-12 RB in every contest this year and is coming off a game in which he scored 35.8 PPR fantasy points. That means Robinson should be in all fantasy lineups in Week 7. The 49ers have let an RB finish top-10 in consecutive weeks.
WR Drake London
Drake London will remain a must-start WR1 in fantasy this week. He just had his best fantasy game of the season last week (31.8 PPR fantasy points) and should continue to be in all fantasy lineups. Four different WRs have totaled over 70 receiving yards against the 49ers in 2025, including both Nacua and Adams in Week 5.
WRs Jauan Jennings/Ricky Pearsall
Pearsall will not play in Week 7 as he continues to deal with a knee injury. As for Jauan Jennings, he will be a riskier flex play. He is reportedly playing with five broken ribs and only caught one pass last week. Additionally, the Falcons have allowed only two WRs to finish inside the top-36 through six weeks.
Pitts has some potential as a TE1 option this week against the 49ers. The Falcons playmaker has caught at least four passes in four of his five games, and San Francisco has allowed five different TEs to score at least 10 PPR fantasy points against them this year. So, Pitts can be a start in 14-plus team leagues.
Injuries:
- Brock Purdy (toe) - Out
- Mac Jones (knee) - Will start
- Ricky Pearsall (knee) - Out
- George Kittle (hamstring) - Expected to Play
- Darnell Mooney (hamstring) - Questionable
Atlanta Falcons Start/Sit Matchups
See the full stats in our Fantasy Football Matchup Ratings Projections
| Player | Start/Sit | Matchup Rating ▾ |
Game Matchup |
| Bijan Robinson, RB | Start | 124.1 | @ SF |
| Drake London, WR | Start | 123.4 | @ SF |
| Parker Romo, K | Risky Start | 109.5 | @ SF |
| Kyle Pitts Sr., TE | Risky Start | 108.2 | @ SF |
| Darnell Mooney, WR | Risky Start | 107.8 | @ SF |
| Atlanta Falcons DEF | Risky Start | 106.9 | @ SF |
| Michael Penix Jr. | Risky Start | 105.9 | @ SF |
| Tyler Allgeier, RB | Risky Start | 105.5 | @ SF |
| Casey Washington, WR | Sit | 104 | @ SF |
| Kirk Cousins | Sit | 91.9 | @ SF |
San Francisco 49ers Start/Sit Matchups
See the full stats in our Fantasy Football Matchup Ratings Projections
| Player | Start/Sit | Matchup Rating ▾ |
Game Matchup |
| Christian McCaffrey, RB | Start | 124.5 | vs. ATL |
| Eddy Pineiro, K | Start | 122.6 | vs. ATL |
| George Kittle, TE | Start | 112.8 | vs. ATL |
| Mac Jones, QB | Start | 112.2 | vs. ATL |
| Kendrick Bourne, WR | Start | 112.1 | vs. ATL |
| Jauan Jennings, WR | Risky Start | 106.9 | vs. ATL |
| Jake Tonges, TE | Risky Start | 102.2 | vs. ATL |
| Demarcus Robinson, WR | Risky Start | 103.9 | vs. ATL |
| Brian Robinson Jr., RB | Sit | 96.8 | vs. ATL |
| Kyle Juszczyk, RB | Sit | 92.4 | vs. ATL |
| San Francisco 49ers DEF | Sit | 78.2 | vs. ATL |
Who Should I Start Tool
Not sure who to start? Check out the Who Should I Start tool:
Compare up to four players and we'll tell you who to start...
Who Should I Start? Who Should I Sit? Some common Week 7 fantasy football lineup decisions are regarding players like Mac Jones, Kendrick Bourne, Kyle Pitts Sr., George Kittle, and more. But not to worry, we are here to help make these decisions and build winning lineups in Week 7.
Week 7 Player Decisions. Set your optimal fantasy football lineups for Week 7 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player's name. In the second box, search for the second player's name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed, we've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, enhanced search results with data to compare, and a slick new interface. We hope you enjoy!
How It Works. Each week, our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do is to select the scoring format. There are three small radio buttons (small circles), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 7 Searches. Curious to see some tough lineup decisions for Week 7 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 7 Searches - Start/Sit Player Comparisons
Below are some popular Week 7 searches and comparisons from our 'Who To Start' tool:
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