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FanDuel Daily Fantasy Football Lineup Picks (Week 4): NFL DFS Advice

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 4 of the NFL season. In this article, I, Justin Bales, will be taking you, the reader, through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. Good luck with your FanDuel DFS lineups!

Editor's Note: If you like FanDuel, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Be sure to check all of our fantasy football rankings for 2025:

 

FanDuel Quarterback - Week 4 DFS Picks

Philip Rivers (vs NO, $8,500)

Rivers has struggled in a couple games this season, which may cause people to avoid him at his price. He gets an elite matchup against the Saints, though, as they have the 25th worst defense in the NFL against the pass. This game should quickly become an offensive showcase, but it should also stay close throughout. The Chargers are -4 point favorites in a game set at 52 points, which is the highest total of the slate. Even though Rivers has struggled a couple times this season, he can be used in all leagues this week.

 

FanDuel Running Backs - Week 4 DFS Picks

DeMarco Murray (at HOU, $7,300) 

Murray is a sneaky option. He's a big part of the Titans offense, in both the running and passing game. He is averaging over five receptions per game, and he's the Titans best red zone option. This looks like a tough matchup on paper, but that isn't the case. The Texans do have the fifth best overall defense in the NFL, but they are ranked 26th against the run. The Titans aren't a team that gives up on running the ball early in games, and Murray is surprisingly cheap for his production this season.

Jordan Howard (vs DET, $5,600) 

Howard will likely be a chalk play this week, but he's a great option for cash games. He's cheap enough to be used in tournaments, as well. He will be taking the majority of the carries for the Bears with Jeremy Langford out for the next few weeks. Howard was also used quite a bit in the Bears passing attack last week, although I do believe he will lose most of those opportunities to Ka'Deem Carey if he is able to suit up this week. Howard displayed great upside in limited action last week, and he's a safe player for his low price tag.

 

FanDuel Wide Receivers - Week 4 DFS Picks

Marvin Jones Jr. (at CHI, $7,600) 

Jones is another player that will likely be chalk this week, but he isn't a player worth avoiding. His price tag still isn't all that high, even though he's coming off an elite game against the Packers. In that game, he saw less targets than both weeks one and two, but it was his best performance of the young season. Jones has a fairly high floor, but his upside is essentially as high as anyone's, and he comes at a bit of a discount compared to other elite options. Jones will continue to see a ton of targets, and he can safely be used in all leagues.

Cole Beasley (at SF, $5,200) 

Beasley has been one of Prescott's favorite targets early in the season. He may receive a few more targets this week, as Dez Bryant is currently doubtful to play this week. The Cowboys get a great matchup against the 49ers, who have been playing at a fast pace this week. Beasley isn't a huge touchdown threat, but he almost scored last week, and he will be catching the ball early and often. He's still fairly cheap, and he's a safe option with solid upside.

 

FanDuel Tight End - Week 4 DFS Picks

Zach Miller (vs DET, $5,000)

Miller's huge game on Sunday Night Football may cause his usage percentage to skyrocket, but he'll still make a great option for his price tag if Jay Cutler is ruled out. Cutler hasn't thrown to his tight end much this season, but his backup, Brian Hoyer, has utilized Miller quite a bit. If Hoyer is under center again, Miller will possess a decent floor with an elite ceiling, and he will make a player that can be used in all leagues. If Cutler is under center, Miller is likely a player to avoid.

 




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REAL-TIME FANTASY NEWS

Pyotr Kochetkov

Dealing With Undisclosed Injury
Tristan Jarry

Expected to Be Available Wednesday
Evgenii Dadonov

Doubtful for Wednesday
J.T. Miller

Joins Team for Road Trip
Joel Kiviranta

Ready to Return Wednesday
Ryan Nugent-Hopkins

Expected to Return on Saturday
Marvin Bagley III

Ruled Out Versus Atlanta
Luke Kennard

Available on Tuesday Night
RJ Barrett

Unavailable Wednesday
Landry Shamet

Out for Wednesday
Nikola Jović

Nikola Jovic Questionable for Wednesday's Matchup With Milwaukee
Bogdan Bogdanović

Bogdan Bogdanovic Considered Questionable for Tuesday
Jauan Jennings

Won't be Suspended
Draymond Green

Will be Questionable for Wednesday Against the Rockets
Goga Bitadze

Downgraded to Questionable
Dereck Lively II

Will Miss At Least 7-10 Days
Paul George

Will Not Play Tuesday against the Magic
Tyrese Maxey

Will Play Tuesday Against the Magic
Omarion Hampton

Chargers Open Omarion Hampton's Practice Window
Joel Embiid

Ruled Out Against Orlando
Lamar Jackson

Returns to Practice
DK Metcalf

D.K. Metcalf Will Be Limited Early in the Week
Isiah Pacheco

Set to Return on Thursday
J.T. Realmuto

Red Sox Showing Interest in J.T. Realmuto
Sonny Gray

Red Sox Acquire Sonny Gray From the Cardinals
Brian Thomas Jr.

Expected to Make his Return in Week 13
Aaron Rodgers

Steelers Have "Great Optimism" Aaron Rodgers Will Play in Week 13
CFB

Jeremiah Smith, Makai Lemon, Skyler Bell Named Biletnikoff Award Finalists
Jayden Daniels

has Been Throwing, Return Timeline Unclear
NFL

As Many as Three NFL Teams Could Have Interest in Hiring Bill Belichick
Tre Johnson

Out Indefinitely With Hip-Flexor Strain
Goga Bitadze

Active Tuesday in Philadelphia
Wendell Carter Jr.

Cleared To Play Against 76ers
Jalen Suggs

Ready to Return Tuesday in Philadelphia
Luke Kennard

Uncertain For Tuesday's Game Against Wizards
Adem Bona

Will Not Play Tuesday Against the Magic
Marvin Bagley III

Listed as Questionable vs. Hawks
Kyshawn George

Could Miss Tuesday's Game
Sam Reinhart

Extends Scoring Streak With Three-Point Effort
Adam Fox

Delivers Two Assists in Monday's Win
Brandon Hagel

Tallies Three Points Against Flyers
Andrei Vasilevskiy

Extends Winning Streak With Shutout Performance
Logan Cooley

Erupts for Five Points in Monday's Win
Mathieu Olivier

Sustains Upper-Body Injury Monday
Zach Werenski

Hurt Against Capitals
Paolo Banchero

Remains Out Tuesday
Isiah Pacheco

Targeting a Return on Thursday
Shohei Ohtani

to Play for Team Japan in 2026 World Baseball Classic
Lamar Jackson

Now Dealing With a Toe Injury
Jake Walman

to Remain Out Tuesday
Ridly Greig

Still Out Monday
Baker Mayfield

Dealing With Low-Grade Shoulder Sprain
Thomas Chabot

Misses Monday's Matchup
Kirill Marchenko

Out Monday
J.T. Miller

Unavailable Monday
Brayden Point

Out Against Flyers
Nikita Kucherov

Good to Go Monday
Chris Godwin

Buccaneers Plan to "Ramp Up" Chris Godwin's Usage
Colorado Rockies

Warren Schaeffer to Stick Around as Rockies Manager in 2026
Ashton Jeanty

Ankle Injury isn't Severe
Jayden Daniels

to Practice This Week, Considered a Long Shot for Week 13
C.J. Stroud

Remains in Concussion Protocol
Mike Evans

Could Return Before End of Regular Season
J.J. McCarthy

in Concussion Protocol
Tyrod Taylor

to Remain the Jets' Starting QB
Shedeur Sanders

to Make Another Start for Browns in Week 13
Tee Higgins

Won't Play on Thanksgiving
CFB

Chris Bell Out for Rivalry Matchup Against Kentucky
Scott Wedgewood

Gives Avalanche Second Consecutive Shutout
Ryan Helsley

Tigers Eyeing Ryan Helsley as a Starter
Dan Hooker

Suffers Second-Round Submission Loss
Marcus Semien

Shipped to the Mets on Sunday
Arman Tsarukyan

Gets Submission Win
Brandon Nimmo

Traded to Texas
Belal Muhammad

Loses Back-to-Back Fights
Belal Muhammad

Ian Machado Garry Outpoints Belal Muhammad
Alonzo Menifield

Suffers First-Round Knockout Loss
Volkan Oezdemir

Gets Back In The Win Column
Jack Hermansson

Gets Knocked Out
Jack Hermansson

Myktybek Orolbai Knocks Out Jack Hermansson
Shamil Gaziev

Suffers First-Round Knockout Loss
Waldo Cortes-Acosta

Shines At UFC Qatar
Tagir Ulanbekov

Suffers Third-Round Submission Loss
Kyoji Horiguchi

Makes Triumphant UFC Return
Adolis García

Rangers Non-Tender Adolis Garcia on Friday
CFB

Beau Pribula Expected to Start Against Oklahoma
Dan Hooker

An Underdog At UFC Qatar
Arman Tsarukyan

Looks To Extend His Win Streak
Ian Machado Garry

A Favorite At UFC Qatar
Belal Muhammad

Looks To Bounce Back
Alonzo Menifield

Looks For His Third Consecutive Win
Volkan Oezdemir

Looks To Get Back In The Win Column
Myktybek Orolbai

Looks To Win Back-To-Back Fights
Jack Hermansson

Makes His Welterweight Debut
Kyoji Horiguchi

Returns To The UFC
Elly De La Cruz

Played Through Partially Torn Quad to End 2025
Tarik Skubal

Tigers "Doubtful" to Trade Tarik Skubal
Raisel Iglesias

Returning to the Braves on One-Year Deal

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