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DraftKings Daily Fantasy Basketball Picks (5/22/21): NBA DFS Lineups

luka doncic NBA dfs lineup picks daily fantasy basketball advice

The top daily fantasy basketball lineup picks for DraftKings on May 22, 2021. Mike Marteny provides NBA DFS analysis and sleeper picks for building optimal DFS rosters.

We've got matinee NBA again, just like the bubble last year. That was the best part of the entire thing. Being able to tune in and watch basketball at any time during the day. Tonight we have two Eastern Conference Series and two Western Conference series tipping off. We have the Bucks and Nets as the favorites in the East with Denver and the Clippers as favorites in the West.

What will we actually see from the Clippers? None of them are listed as out or even questionable, so for the first time in what feels like months, we might see a serious lineup from them. We know that Victor Oladipo, Jaylen Brown, Will Barton, Jamal Murray, and P.J. Dozier are out tonight. The only regular member of rotations that we are waiting on a status for is Time Lord. Nice, isn't it?

This article will supply you with my daily fantasy basketball lineup picks for the DraftKings on 5/22/21. You can also check out today’s FanDuel lineup picks. It’s also important to monitor injury news as a result of COVID-19 as the slate can completely change before line-up lock. Without further ado, let’s dive into the picks! 

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DraftKings DFS Guards

Luka Doncic - PG/SF, at Clippers ($10,500)

It's hard to fade Giannis, but he has enough players around him that can step up if he has an off game. Luka doesn't have that luxury, but it also creates a higher ceiling for the Mavs star. Luka ran wild on the Clippers all three times this year, putting up 190.25 DraftKings points in 106 minutes of court time. Considering most of the Clippers core hasn't played that many games together, I think Dallas in general and Luka in particular can have some success in this series even if they don't win it. It feels like Luka has the highest ceiling of any player in this set of the NBA playoffs.

Kyrie Irving - PG/SG, vs. Boston ($9,200)

You can say a lot of things about Kyrie last year and into this year, but the one constant is that he has dominated his former team. No matter who is in the lineup along with him, he plays like a man possessed against Boston. Irving put up 172.75 DraftKings points in 102 minutes in the three games against Boston this year. I expect to see Irving front and center this series, which will be why I'm fading James Harden for the next fortnight. The jury is still out on K.D.

Tyler Herro - PG/SG, at Milwaukee($6,000)

Does Herro have any of that playoff magic left over from last year? Herro wasn't the most consistent guy this year, which makes me a bit apprehensive about this play. However, he did perform well two of the three games against the Bucks this year. Herro put up 98.5 DraftKings points on Milwaukee despite a dreadful 12 DraftKings point performance in just 18 minutes of court time in the last weekend of the season. I'll chalk that up to poor shooting. The bad part about this is that Miami is so deep that they don't need to keep a guy whose shot isn't falling on the floor. However, I put more stock into the first two outings of the season than the last one.

Facundo Campazzo - PG/SG, vs. Portland ($5,200)

There was a lot of unrest in the Denver backcourt when Murray first went down, but Campazzo gradually stepped into the role and by the middle of May, was performing reasonably well. Don't play Campazzo expecting him to be the fill-in for Murray. They are completely different players. That's not to say that Campazzo doesn't help the team and can't help your DFS lineups. That's not the case. Just keep in mind that his ceiling isn't nearly as high as Murray's and the floor is much lower. This offense doesn't revolve around him like it does Murray. It continues almost in spite of Campazzo.

Bonus Guards: Damian Lillard ($9,400), Paul George ($7,800), Donte DiVincenzo ($5,100), Rajon Rondo ($4,400)

 

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DraftKings DFS Forwards

Jayson Tatum - PF, at Brooklyn ($10,100)

Tatum flipped the switch to playoff Tatum in the play-in game, smoking the Wizards for 73.5 DraftKings points. The Nets are better than the Wizards up front, but Jaylen Brown is still out. Tatum is going to take over this team again. The Celtics will go how he goes. Tatum put up solid numbers against Brooklyn during the regular season, but they were without Durant and the Celtics had Brown for all of those games. We can't really gauge what Tatum is going to do. I'll just say that it's the playoffs, and Tatum is one of those guys that shows up in the playoffs.

Michael Porter Jr.  - SF/PF, vs. Portland ($8,200)

I am a little bit worried about the synchronicity of the Nuggets here. They screwed around the last two games of the season knowing that they couldn't move up or down in seeding. Porter, who had been the leading scorer in most games for the Nuggets down the stretch, played just 38 minutes in two games and didn't look all that great in either one. Porter is one of those guys that needs minutes to really get going. He'll get them here, but I do wonder if he and the rest of the team come out cold. That might affect their bottom line.

Aaron Gordon - SF/PF, vs. Portland ($5,000)

Gordon's talents have been mostly wasted in Denver, but that could change in the playoffs. Porter is enough of a hybrid to play wherever they need him. If Denver decides to run bigger against Portland, we could see Gordon start since the Nuggets aren't particularly deep at guard anyway. This is a large-field GPP play only and mostly based on a gut feeling that Denver has been waiting until the right moment to use Gordon, much like Miami did with Goran Dragic last year. This feels like a series where Gordon could be effective, but again, this is a deep field dart only. Gordon's price is just low enough for this to pay off nicely.

Blake Griffin - PF/C, vs. Boston ($4,400)

Yes, Griffin is a shadow of the player that he formerly was, but he has proven to be effective in 25 minutes off the bench against the opposing team's second string. That should be the case for Griffin in this series as well. Boston somehow survived the season again with atrocious post defense. That's not going to fly with Blake and K.D. running at you. Griffin doesn't have enough upside to break a slate, but he looks like a strong bench piece and he's priced low enough to get good value out of him.

Bonus Forwards: Giannis Antetokounmpo ($10,700), Kevin Durant ($9,700), Norman Powell ($5,700), Joe Harris ($4,700),

 

DraftKings DFS Centers

Nikola Jokic - C, vs. Portland ($10,600)

If you take away the 17-minute warmup that Jokic had against Portland in the regular season finale, he put up 102.5 DraftKings points in just 73 minutes against Portland this year. Murray played in one of those games. I still think that Luka has a higher ceiling, especially given the way that Michael Porter scored for the Nuggets in the last month. However, I think his floor might be the highest of the five-figure players on this slate. The offense is still going to run through Jokic no matter who is on the court with him.

Jusuf Nurkic  - C, at Denver ($7,200)

Normally I wouldn't run centers at Denver, but this is the team that Nurkic originally played for. On top of that, he racked up 45.75 DraftKings points in just 20 minutes against the Nuggets with Jokic in there for most of those minutes in the regular season finale. We wont see a truly big game out of Nurkic because Portland wont run him more than 30 minutes. Why would they with Enes Kanter around? Still, Nurkic is a guy that can put up points in a hurry when he's on the court.

Serge Ibaka - C, vs. Dallas ($4,500)

This price is a joke. The Clippers eased Ibaka back, but he put up 56 DraftKings points in just 36 minutes over the last two games of the season. True, it wasn't great competition, but Serge looked like he did back in December. He was a hell of a bargain then too. Ibaka likely wont go more than 25 minutes, but I'm not sure it matters. He put up 36 DraftKings points on the Warriors in just 23 minutes back in March 11. There is a track record for Ibaka's output even in limited minutes.

Bonus CentersBam Adebayo ($8,300), Tristan Thompson ($5,000), Brook Lopez ($4,500)



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REAL-TIME FANTASY NEWS

Kevin Huerter

is Available for Game 6
Duncan Robinson

is Returning for Game 6
Caris LeVert

is Cleared for Game 6 on Friday
OG Anunoby

Practices in Full on Friday
Terrence Shannon Jr.

is Tagged as Questionable for Friday
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Luther Burden III

Does Luther Burden III Have WR1 Dynasty Upside in Chicago?
MarShawn Lloyd

Can MarShawn Lloyd Emerge as a Top Dynasty Handcuff Option?
Emanuel Wilson

Can Emanuel Wilson Carve Out a Consistent Role in Seattle?
Max Fried

Heading to Injured List With Elbow Bone Bruise
Jaylin Noel

Playing-Time Outlook in Houston Remains Unclear
Dylan Sampson

Role in Cleveland Looks Secure Heading into 2026
Kirk Cousins

' Dynasty Value Fading Ahead of First Season in Las Vegas
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
George Holani

Dynasty Outlook Remains Cloudy
Jordan Westburg

to Have Season-Ending Elbow Surgery
Kendre Miller

Quickly Fading From Fantasy Relevance
Keon Coleman

Is Keon Coleman a Hopeless Dynasty Asset?
Marvin Harrison Jr.

a Buy-Low Candidate in Dynasty Formats
Hollywood Brown

a Cut Candidate in Dynasty Leagues?
Darnell Mooney

Barely Inside Top-100 WR Dynasty Rankings
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Christian Kirk

Can Christian Kirk Revive his Career in Bay Area?
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
Brashard Smith

Destined to Become Special Teams Player?
MMA

Dohoo Choi Returns At UFC Vegas 117
Ben Sinnott

Dynasty Value Hindered by Free-Agent TE Addition
Juan Diaz

Set To Make His UFC Debut
Sam Darnold

Should Dynasty Managers Continue to Hold Sam Darnold?
Malcolm Wellmaker

Looks To Bounce Back
Justin Fields

Dynasty Managers Getting Ready to Sell High on Justin Fields?
Christian Edwards

Set For His UFC Debut
Dallas Goedert

a Target for Dynasty Managers in Championship Window?
Modestas Bukauskas

Looks To Get Back In The Win Column
Theo Johnson

Not the Primary Option in New System?
Kyle Monangai

Still Time to Buy Low on Kyle Monangai in Dynasty Leagues?
Tarik Skubal

Resumes Playing Catch, Ahead of Schedule?
Amon-Ra St. Brown

an Unheralded Dynasty Cornerstone
Karl-Anthony Towns

Making an Impact as Playmaker in Playoffs
Jalen Duren

Determined to Improve
Kevin Huerter

Tagged as Questionable for Game 6 Against Cavaliers
Caris LeVert

Considered Questionable for Friday
Duncan Robinson

Iffy for Game 6
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
Pavel Dorofeyev

Enjoys Second Consecutive Multi-Goal Game
Shea Theodore

Records Two Points in Game 6 Win
Mitchell Marner

Scores Special Goal in Series-Clincher
Ryan Johnson

Takes Over as Canucks GM, Sedins Promoted to Co-Presidents
Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Paul Reed

Makes Big Impact Off the Bench Wednesday
Daniss Jenkins

Contributes 19 Points As Starter
Cade Cunningham

Tallies 39 Points in Losing Effort
Max Strus

Notches 20 Points With Six Triples
Evan Mobley

Close to Triple-Double Wednesday
Jarrett Allen

Records Double-Double in Game 5 Win
James Harden

Leads the Way for Cavaliers in Game 5 Victory
Quinn Hughes

Finishes Postseason With 15 Points
Matt Boldy

Posts Two Assists in Season-Ending Loss
Scott Wedgewood

Perfect in Relief Effort
Martin Necas

Records Another Multi-Point Game
Brett Kulak

Sends Avalanche Into Conference Finals
Brayden McNabb

Suspended for One Game
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
Juan Soto

Exits Wednesday's Game Early with Ankle Injury
Kevin Huerter

is Cleared to Return for Game 5
Caris LeVert

is Available for Game 5 on Wednesday
Duncan Robinson

is Out for Game 5
Keegan Murray

Undergoes Ankle Procedure
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF