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DraftKings Daily Fantasy Baseball Lineup Picks (9/28/16): MLB DFS Advice

It's a full slate of MLB games on DraftKings for Wednesday's contests, as there is one game in the early afternoon and the remaining 14 contests take place in the evening. Because there's (can be) only one day game (Highlander) I'm going to focus on the evening games so that you can apply this advice to all of the evening and late contests.

In this article, I will be providing you with my daily fantasy baseball MLB lineup picks for DraftKings on 9/28/16. The DFS lineup picks will range from high-priced to low-priced options and identify options who will out-perform their expectations, including sleepers and value plays on DraftKings. The following targets have been selected for all evening and late contests.

Editor's Note: Purchase a full season NFL Premium Pass (including DFS Premium), and also get MLB Premium + DFS for free through the playoffs. Premium DFS research, lineup picks, expert lineups, tools and more. You can see screenshots of our NFL Premium and MLB Premium and DFS tools. What are you waiting for?

 

DFS Lineup Stacks to Target on DraftKings

Los Angeles Dodgers vs. Luis Perdomo (RHP)

The Dodgers have destroyed RHP this season to the tune of a .264/.332/.440 triple slash that is good for the fourth best AVG, fourth best OBP and fifth best SLG in all of MLB against RHP. In case you're wondering their slugging percentage is .772 against RHP and that's also the fifth best mark in the league. Not only do the Dodgers hit RHP, but they have shelled Padres SP Luis Perdomo this season as well, as they've managed to score 20 runs (18 earned) against him in just 18 innings of work. I would expect more of that on Wednesday and I would be happy to stack up the Dodgers including but not limited to Corey Seager, Yasmani Grandal, Chase Utley, Howie Kendrick, Yasiel Puig, Adrian Gonzalez and Justin Turner. Oh, and fee free to use their SP Jose De Leon too.

Boston Red Sox vs. Bryan Mitchell (RHP)

Bryan Mitchell has posted a 1-5 record with a 5.06 ERA and 1.65 WHIP over 58 and 2/3 innings pitched. This season the Boston Red Sox have posted a show stopping quadruple slash of 2.86/.350/.471/.821 against RHP. That is the best AVG, OBP and OPS in the league and the second best SLG (and it's only one percentage point behind the league leading Rockies who play half of their games at the hitter's paradise of Coors Field). Nothing else to say here. It should be a massacre. Use any and all Red Sox.

 

DFS Starting Pitchers to Consider on DraftKings

Jose De Leon, LAD at SD- $8,500

Jose De Leon has been up and down thus far in his brief MLB career as he's allowed three, two and four earned runs in this three starts, but never pitched more than six innings in any single start. What Jose has done well in his small MLB sample is strike batters out, as he's K'd 14 in 14 and 2/3 innings pitched. That ability is bolstered by the fact that the Padres strike out in 25% of their at bats, the second worst mark in the league. So even if Jose gets blow up again, like he was last time out in Arizona, he should be a great source of strikeouts. At DK that means lots of points as K's are worth two points each. That should help Jose get into the low to mid twenties and be a solid value play on Wednesday night.

Seth Lugo, NYM at MIA - $5,400

Seth Lugo has been solid for the Mets this season as he's managed to post a 4-2 record, a 2.61 ERA, 1.06 WHIP and a K:BB ratio of 43:18 across 58 and 2/3 innings pitched. At DK Lugo has more than tripled his price tag in fantasy points per game in four of his last six outings, but not in his last two. I think he does that again and is a good bet for more than 17 points. This would make him a solid value play on a night when he's possibly a contrarian play as well.

 

DFS Infielders to Consider on DraftKings

Catcher (C)

Yasmani Grandal, LAD at SD - $4,100

Grandal has been hotter than a Guatemalan insanity pepper over the past week (four games and three starts) as he's mashed to the tune of a .545/.643/.1.182 triple slash while cranking two HR and notching seven RBI. I might be insane to fade Gary Sanchez, but Grandal is $1,000 cheaper and it doesn't hurt that he's slugged .503 against RHP this season with 13 doubles, a triple and 23 HR in just 310 at bats. If you want to roster Gary I understand, but I'm on team Yasmani on Wednesday.

First Base (1B)

Trey Mancini, BAL@ TOR - $2,300

While it's only a seven at bat sample size Trey has managed three HR and a double against LHP this season. On Wednesday he'll face LHP Francisco Liriano and the Blue Jays at the hitter friendly Rogers Centre in Toronto. This season Liriano has allowed RHH a triple slash line of .257/.353/.443 along with 19 doubles, two triples and 21 HR in just 460 at bats. I think Trey stays hot against lefties and notches another extra base hit on Wednesday. Make sure that he's in fact in the lineup. If he is he just might be the best value play of the night, so join me and get him in all your lineups.

Second Base (2B)

Trea Turner, ARI@ WAS - $5,600

Trea Turner has been ridiculously hot lately as he's managed to crank out 17 hits including two doubles, a triple, four HR and three SB in his past 11 games (10 starts). He's obviously really expensive on Wednesday night, but I think that he's well worth paying up for as he gets to face RHP Shelby Miller. Not only has Miller been terrible, but Trea has slugged an amazing .610 against RHP this season with 31 extra base hits in only 231 at bats this season. There are a few cheaper guys that I like, but none that are even close to Turner so pay up.

Shortstop (SS)

Manny Machado, BAL at TOR - $3,800 

While I really like Corey Seager on Wednesday, I simply can't fade Manny Machado at this price, especially when he's facing a LHP. As I noted above with Mancini the Orioles will face LHP Francisco Liriano at the Rogers Centre. This bodes well for Machado as he's crushed LHP to the tune of a .338/.402/.531 triple slash this season. At the Rogers Centre this season Manny has slugged .586 with two HR. All of this adds up to a great value, so don't let it slip through the cracks.

Third Base (3B) 

Justin Turner, LAD at SD - $5,100

Justin Turner is really expensive on Wednesday, but he's well worth paying up for as he'll face RHP Luis Perdomo. As I noted above the Dodgers are great against RHP and Turner is one of the main reasons why, as he's slugged .566 with 52 extra base hits against them this season. Over the past week Turner has been on fire NBA Jam style as he hit .500 in his past five games (four starts). Hopefully Justin is so expensive that other owners stay away from him, because I think that he's going to have a yuuuge night.

 

DFS Outfielders to Consider on DraftKings

Mike Trout, OAK at LAA - $5,700

Mike Trout has been blazin' hot over his past six games as he's slugged .684 with a double, two HR and a SB. Trout has been great all season as he's leading the league in runs scored, walks, OBP and OPS+. When in doubt, start Mike Trout is a pretty good DFS motto. It's even better when there's no doubt, as is the case with his matchup on Wednesday, as Trout has been a much better hitter at home. Sonny Gray will start for the Athletics, but he's unlikely to pitch for much more than an inning, so Trout will get roughly eight frames against the bullpen. I like them apples.

Mookie Betts, BOS at NYY - $5,600

Mookie Betts has been the east coast version of Trout this season as he's combined power and speed with a huge amount of counting numbers that rival Trout's. Mookie has been when of the biggest reasons why the Red Sox have been so good against RHP this season as he's managed to hit 23 HR and steal 23 SB while slugging .546 against RHP this season. Those would be good numbers for most people in an entire season, not just against RHP. Although Mookie are expensive there is lots of cash to spend because of the values and cheap SP. Join me and place your Betts.

Andrew McCutchen, CHC at PIT - $3,900

Similar to Manny Machado I simply cannot pass up this player at this price point. It appears that Andrew has a bad matchup with Jake Arrieta, but he's actually notched a solid .297 AVG and a .395 OBP against Arrieta in 37 at bats. Meanwhile McCutchen has been very good of late as he's managed a .385/.450/.750 triple slash over his last 13 games. Not only will McCutchen be a solid value play, but he'll also be a contrarian option as well.

 

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REAL-TIME FANTASY NEWS

Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Aaron Rodgers

Signs One-Year Deal With Steelers
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Alex Lyon

Likely to Start Game 6 Against Canadiens
Owen Power

Available Saturday
Isaac TeSlaa

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Troy Franklin

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Trevor Lawrence

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Courtland Sutton

in Line for Reduced Role in Denver?
KC Concepcion

Can KC Concepcion Immediately Assume the WR1 Role in Cleveland?
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' Dynasty Outlook Clouded by Uncertain Future in Dallas
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Deebo Samuel Sr.

Now Only a Gadget Player/Kick Returner?
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Offseason Additions Hurt Elic Ayomanor's Dynasty Outlook
Tyler Warren

a Clear Top-Five Dynasty Tight End
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a Dynasty RB to Target Despite Injury History?
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Currently in a Dynasty Buy Window Amid Rollercoaster Offseason
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Timing Becoming Key to Acquiring A.J. Brown in Dynasty
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Isaiah Likely

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Duncan Robinson

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Cade Cunningham

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Jalen Duren

Bounces Back With Double-Double
Anthony Edwards

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Victor Wembanyama

Tallies 19 Points in Friday's Win
De'Aaron Fox

Highly Effective in Blowout Win
Stephon Castle

Shines in Series-Clincher
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Austin Reaves

Could Command $40M Per Year With New Contract
Jalen Duren

Available to Finish Game 6
Yanic Konan Niederhauser

Not Expected to Be Ready for Start of Next Season
Jalen Williams

Declares Himself Healthy for Conference Finals
Terrence Shannon Jr.

Will Play Friday Night
Kevin Huerter

is Available for Game 6
Duncan Robinson

is Returning for Game 6
Caris LeVert

is Cleared for Game 6 on Friday
OG Anunoby

Practices in Full on Friday
Terrence Shannon Jr.

is Tagged as Questionable for Friday
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Luther Burden III

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MarShawn Lloyd

Can MarShawn Lloyd Emerge as a Top Dynasty Handcuff Option?
Emanuel Wilson

Can Emanuel Wilson Carve Out a Consistent Role in Seattle?
Max Fried

Heading to Injured List With Elbow Bone Bruise
Jaylin Noel

Playing-Time Outlook in Houston Remains Unclear
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
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College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Jordan Westburg

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Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
Tarik Skubal

Resumes Playing Catch, Ahead of Schedule?
Karl-Anthony Towns

Making an Impact as Playmaker in Playoffs
Jalen Duren

Determined to Improve
Kevin Huerter

Tagged as Questionable for Game 6 Against Cavaliers
Caris LeVert

Considered Questionable for Friday
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
Pavel Dorofeyev

Enjoys Second Consecutive Multi-Goal Game
Shea Theodore

Records Two Points in Game 6 Win
Mitchell Marner

Scores Special Goal in Series-Clincher
Ryan Johnson

Takes Over as Canucks GM, Sedins Promoted to Co-Presidents
Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Quinn Hughes

Finishes Postseason With 15 Points
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF