🖥 CYBER MONDAY - TAP TO SAVE 50% WITH CODE CYBER
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

College Football Betting Picks for Week Four (9/25/2021)

Our college football CFB betting picks for Week Four. Every week, Nick recommends the best CFB bets and top CFB wagers for the college football betting slate.

As we enter Week Four of the college football season, the top teams are starting to cement their places in the rankings. Penn State and Michigan suddenly look like the favorites in the Big Ten, Clemson seems to be beatable, and the level of parity this season is higher than we've seen in over a decade. Still, with all these changes, the one constant is that Alabama and Nick Saban could completely rebuild their offense and defense after a host of NFL departures, yet hardly miss a beat with last week's big win at The Swamp.

The rumors of our demise were greatly exaggerated with a monumental bounce-back 3-0 performance in Week Three. Kent State hung with Iowa until the fourth quarter, en route to an easily cashed under. Similarly, in College Station, the New Mexico Lobos gained zero traction as the under hit by nearly twenty points. And in the late game, Coach Mike Gundy's Oklahoma State Cowboys traveled to the iconic blue turf of Boise State and went home with a road upset victory as 4-point underdogs. The season-long record is 7-6, with bettors cashing the Cowboys at +180 on the money line.

For Week Four of the college football season, here are some expert money-line and over/under betting picks.

Be sure to check all of our fantasy football rankings for 2025:

 

Boise State @ Utah State (+9.5)

O/U: 70.5

After a loss at home as a favorite, coach Andy Avalos' Boise State Broncos make the four-hour drive south to Logan, Utah. In last week's loss to the Oklahoma State Cowboys, quarterback Hank Bachmeier had an uneven performance and did little to quell the doubts about his status as the unquestioned starting quarterback. In the team's two losses to UCF and Oklahoma State, the Broncos held a lead only to squander it away in a narrow loss. The schedule should get considerably more favorable as Boise State enters conference play, but it is apparent that this is not a team with the typical talent or pedigree of a normal Boise State team that most are accustomed to. The Broncos have competed in five consecutive Mountain West Conference championship games, but have a significant amount of work ahead of them if they hope to extend their streak to a sixth year.

Coming off a 1-5 performance in the abbreviated 2020 season, expectations were low in Logan, Utah. New head coach Blake Andersen came on board from Arkansas State, bringing along his quarterback Logan Bonner and a pass-happy offense that has jumpstarted its way to a 3-0 start. Andersen brought along a host of transfers this off-season, and the impact is showing across the board, especially with his offensive line that has allowed a mere three sacks in as many games so far. The offense has hummed in wins over Washington State, North Dakota, and Air Force, while the defense has shown a knack for forcing turnovers, led by graduate transfer linebacker Justin Rice and his 10 tackles per game and three interceptions.

The opportunity to showcase these teams on CBS was too much for the programs and the Mountain West Conference to pass up, but the unfortunate implication is that they'll be playing at noon eastern time (10:00 am mountain time). The 10:00 local start marks the earliest game in Utah State football history, as well as their first-ever game broadcast nationally on CBS. The coaches will do everything they can to prepare their teams, but such an early game is a tall and unusual task for both teams.

Pick: Under 70.5

 

Want some more CFB DFS tools? If you like what you see here, don't forget to sign up for your RotoBaller CFB DFS Premium Pass. Use code BALLER and receive 10% off your purchase! You'll love the College Football DFS Lineup Optimizer, DFS Cheat Sheets Premium Slack Chatrooms to help you out in real-time.

 

Kentucky at South Carolina (+5)

O/U: 48.5

The progression of Kentucky from a basketball blue-blood to a basketball blue-blood that also fields a decent football team has not been an easy path. Under head coach Mark Stoops' leadership, the Wildcats are 52-50 overall but have won their last three bowl games and earned their first ten-win season since 1977 only a few seasons ago. At quarterback, Penn State transfer Will Levis started the season strong in wins over UL-Monroe and Missouri but faltered badly with a pair of interceptions against FCS-level Chattanooga. The 28-23 win over the Chattanooga Mocs hopefully served as a wake-up call to the 'Cats that they can't take a week off, especially important as they travel to one of the SEC's cellar dwellers. The rushing attack, spearheaded by Christopher Rodriguez and Kavosiey Smoke is the team's strength on offense, and they're complemented by a solid top two receiver duo of Wan'Dale Robinson and Josh Ali. If the defense can generate more turnovers, this team could be a sleeper in what appears to be a weakened SEC East.

The South Carolina Gamecocks won their first two games with former North Dakota State quarterback Zeb Noland at the helm. Noland came to South Carolina after his spring 2021 season with the Bison as a graduate assistant coach but was sprung into duty with his final season of eligibility because of an injury to starter Luke Doty. Noland served his role as a game manager but ceded his way to Doty who returned to appear in the Gamecocks' blowout loss to Georgia last week. The running backs have yet to truly break out, but the duo of JuJu McDowell and Marshawn Lloyd has the speed to burn and can make their opponents pay with a big play.

As the SEC slowly enters conference play, the true mettle of many teams will be revealed. Kentucky, if they have any hope of competing for a division title, should walk into this game with an aggressive approach and a need to make a quick impression. On the other hand, South Carolina has enjoyed a mini resurgence with a 2-1 start under new head coach Shane Beamer and will need their quarterback Doty to play with poise and precision. Do not expect the defenses to factor much into this game - Kentucky has been able to strike for their fair share of big plays this year, and South Carolina gets the benefit of a healthy young quarterback at the helm.

Pick: Over 48.5

 

Hawaii at New Mexico State (+17)

O/U: 62

When Todd Graham was hired as the Pitt head coach in 2011, he infamously coined the phrase "high-octane offense" as his system. Since his one-year stint in the 'Burgh and a briefly longer stay in charge at Arizona State, Graham's offenses have not held up to that lofty expectation but have been formidable. Quarterback Chevan Cordeiro has played poorly, tossing five interceptions compared to a mere six touchdowns in the Rainbow Warriors' 1-3 start. Swiss-Army knife Calvin Turner, who transferred before the 2020 season after his previous school (Jacksonville U.) shut down its football program, has not been able to muster much yardage on the ground but does pace the team with five total touchdown scores and 41 total touches. Defensive lineman Jonah Laulu has been an early bright spot, garnering three sacks so far. A 1-3 start is not ideal, but considering the losses that came at the hands of UCLA, Oregon State, and San Jose State, the team should enter this week with the hope of turning around their season with hopes of a bowl game on the horizon.

Coach Doug Martin's Aggies finally etched their name in the win column with a 43-35 victory over South Carolina State. The team had lost its first three games by a combined 56 points, hardly putting up much of a fight. Sophomore quarterback Dino Maldonado started the season as the third-string at the position but catapulted his way to the top due to the ineptitude of his higher-ups. The Aggies' dilemma of poor skill position players still exists, as no running back is averaging better than 3.8 yards per carry. The defense, meanwhile, has been a strong point forcing five interceptions and 26 tackles for loss in the early going.

Hawaii's performances under coach Graham have been maddeningly inconsistent, a fact that is unlikely to change midseason. Outside of the win over Portland State, the Rainbow Warriors have averaged a mere 16 points per game, showing little signs of life. On the other side of the ball, New Mexico State finally showed some signs of life on offense in last week's win over South Carolina State, but you have to consider the opponent.

Pick: Under 62



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis

POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Sauce Gardner

Officially Week-to-Week with Strained Calf
CFB

Lane Kiffin to Make $13 Million Salary, Ties Kirby Smart
CFB

Buster Faulkner, Joey Halzle Candidates for Florida Offensive Coordinator Job?
CFB

Kentucky Officially Fires Mark Stoops
Justin Herbert

Has Metacarpal Fracture in Left Hand
Amon-Ra St. Brown

Week 14 Availability Up in the Air
VEG

Carter Hart Expected to Make Golden Knights Debut Tuesday
Andre Drummond

Leaves Early, Status Now in Question
Pyotr Kochetkov

Remains Without Timeline For Return
Boone Jenner

Close to Returning
Tre Mann

Uncertain for Monday's Game Against Nets
Lian Bichsel

Exits With Injury Sunday
Deandre Ayton

Leaves Game With Knee Soreness
Petr Mrazek

Injured in Sunday's Loss
Adam Fox

Placed on Long-Term Injured Reserve
Brandon Williams

Questionable With Adductor Issue
P.J. Washington

Uncertain For Monday's Contest
Daniel Gafford

Expected To Miss Second Straight Game
Zach Ertz

Leads Washington in Receiving in Overtime Loss
James Cook

Handles Career-High 32 Carries for 144 Yards in Win
Egor Demin

Available Against Hornets
Justin Herbert

Planning to Play Through Broken Bone in Left Hand in Week 14
Terance Mann

in Danger of Missing Monday's Game
Sauce Gardner

Likely to Miss a "Couple of Weeks" With Calf Strain
Noah Clowney

Considered Probable for Monday
Michael Porter Jr.

Listed as Probable for Monday's Matchup
Caris LeVert

Expected Back Monday
Duncan Robinson

Questionable to Face Hawks
Jalen Duren

Likely to Return Against Hawks Monday
Brock Bowers

Records Two Touchdown Grabs in Week 13
Alexandre Sarr

Iffy for Monday
Mark Williams

Available Against Lakers Monday
Ryan Dunn

on Track to Return Monday
Jaime Jaquez Jr.

Uncertain for Monday
Coby White

Returning to Bulls Lineup Monday
Paolo Banchero

Unavailable Monday
Larry Nance Jr.

to Miss 3-4 Weeks
Jarrett Allen

to Miss a Week of Action
Justin Herbert

Suffers Fractured Hand in Week 13, Will Have Surgery
Kimani Vidal

has Season-High in Rushing Yards in Win Over Raiders
De'Von Achane

Looks Unstoppable on the Ground in Week 13
Davante Adams

has Another Two-Touchdown Game
Aaron Jones Sr.

is Questionable to Return With Shoulder Injury
Adonai Mitchell

has Career Day With 102 Yards, Touchdown in Win
Bijan Robinson

Compiles 191 Total Yards, Touchdown in Loss to Jets
Shedeur Sanders

Will Start Again in Week 14 Against Titans
Mike Evans

Could Return in Week 14
Keon Coleman

Active for Week 13
Dalton Kincaid

Officially Inactive for Week 13
Kyren Williams

Returns in Week 13 After Injury Scare
Kyren Williams

Suffers Apparent Leg Injury in Week 13, Status Unclear
CFB

Lane Kiffin to be Introduced as LSU's Next Head Coach on Monday
CFB

Florida Poised to Land Jon Sumrall as Next Head Coach
CFB

Alex Golesh Taking Over Auburn Head-Coaching Job
CFB

Arkansas Expected to Hire Ryan Silverfield as Next Head Coach
Joel Hofer

Shuts Out Mammoth
Owen Tippett

Amasses Three Points in Saturday's Win
Stuart Skinner

Bounces Back With Shutout
Brock Nelson

Notches Four Points in Big Win
Oliver Ekman-Larsson

Sustains Upper-Body Injury
Logan Cooley

Hurt in Saturday's Loss
Warren Foegele

Not Ready to Return Saturday
Simon Benoit

Won't Play Saturday
Henri Jokiharju

Lands on Injured Reserve
Zack Wheeler

Likely to Return in May
Pavel Zacha

a Game-Time Call Saturday
Ryan Helsley

Agrees to Two-Year Deal With Orioles
David Pastrnak

Out for Second Consecutive Game
William Nylander

Available Saturday
Kyle Palmieri

Out for 6-8 Months With Torn ACL
Jake Walman

Sidelined for Third Consecutive Game
Jack Roslovic

to Miss Two Weeks
Dylan Cease

Agrees With Blue Jays on Seven-Year, $210 Million Deal
Anthony Rendon

Angels Could Buy Out Final Year of Anthony Rendon's Contract
Josh Hader

Says his Shoulder is "Back to Normal"
Ketel Marte

Diamondbacks "Actively Listening" on Ketel Marte
J.T. Realmuto

Red Sox Showing Interest in J.T. Realmuto
Sonny Gray

Red Sox Acquire Sonny Gray From the Cardinals
CFB

Jeremiah Smith, Makai Lemon, Skyler Bell Named Biletnikoff Award Finalists

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP