Jamie Calandro's Week 6 Fantasy Football Rankings - The Industry's Top Accuracy Ranker

October 12, 2025

Fantasy football Week 6 rankings for RB, WR, TE, QB from the #1 most accurate ranker in 2025 Jamie Calandro. Read his fantasy rankings analysis and outlooks.

RotoBaller writer Jamie Calandro shares his Week 6 fantasy football lineup rankings for RB, WR, TE, and QB. After five weeks, Jamie's is second on the leaderboard at FantasyPros among the most accurate player rankings in the industry! The following includes analysis that will hopefully help you make some tough decisions when it comes to sit/start. Jamie is also on X @jac3600 and in our RotoBaller Discord channel, answering questions.

Regular starting options are included to highlight that some of your must-start players have a good chance of supplying winning totals. Much of the analysis helps fantasy players make the tough decisions between two or more similarly valued players.

The rankings are updated as news breaks until the full slate begins on Sunday. Following the positional advice below, you can consult the player rankings tables. The fantasy football lineup rankings analysis is based on half-PPR scoring rules.

Quarterback Rankings – Fantasy Football Week 6

Drake Maye is ascending to "high-end QB1" status. The Saints have allowed the fifth-highest passer rating and the seventh-most FPPG to opposing QBs, along with the seventh-most QB rushing yards. ... Justin Fields has an extremely difficult draw against Denver, but is still a viable low-end QB1 in London thanks to his rushing upside.

I'm optimistic Joe Flacco's ability to push the ball downfield will revitalize this Bengals' offense, but is not the week. He's a status back there, and Cincinnati has allowed the second-highest pressure rate. ... Mac Jones has been a QB1 in two of his three starts, and Tampa Bay is a pass funnel defense that has allowed the second-highest success per dropback.

Running Back Rankings – Fantasy Football Week 6

Rico Dowdle handled 23 of a possible 27 carries and also received four targets in the passing game. He averaged 9.0 YPC against Miami and now gets a revenge game against the Cowboys, who have allowed the most yards per play, along with the sixth-most FPPG to opposing RBs.

The Seahawks have allowed the second-lowest YPC this season (3.3), but have also given up the most receptions to the position. I'm still in on Travis Etienne despite the tough matchup. ... Jaylen Warren SHOULD be in a great spot after seeing his snap share rise exponentially over the first three weeks, but it makes sense to wonder if he'll lose snaps to Kenneth Gainwell after missing last game with a knee injury. I still have him as an upside RB2.

Treat Michael Carter with care. He was clearly the main back last week for Arizona, but the Colts' D is solid, and there's a good chance Jacoby Brissett is under center. ... I really want to keep running Chase Brown out there, but the Bengals have an implied total of 15.5 points against Green Bay's stout defense.

Jacory Croskey-Merritt!! The golden child of X finally busted out for Washington last week with 150 total yards and two TDs on 16 touches. This week, he gets the Bears on Monday night, and they've allowed the second-most rushing yards on the season, along with the second-most yards per play. He should destroy Chicago. Go, Bill, go!

The Chargers' RBs are a crapshoot. I ASSUME Hassan Haskins will start as the lead back and get the goal-line carries, but Kimani Vidal is the more athletic player. Neither in safe since we don't know the snap breakdown, but both are viable in a pinch as Miami's run defense is the worst in the league.

Wide Receiver Rankings – Fantasy Football Week 6

It's not looking good for Lamar Jackson to return in Week 6, which makes me very bearish on all Ravens' pass catchers, including Zay Flowers. I'm cautiously ranking him as WR24 for talent alone, but do not argue sitting him for the likes of Keenan Allen, Michael Pittman Jr., or even Kendrick Bourne.

Speaking of Bourne, he's an excellent start this week in all formats with the SF WR corps likely banged up again. Bourne was electric last week, going 10-142-0 on 11 targets, and the Bucs are a pass funnel defense. ... The Chargers are a tough test, but Jaylen Waddle had nine targets and a 46% air yards share. He's a must-start with his expanded role.

Quentin Johnston's injury status looms large. With the Chargers down to bare bones at RB, they should lean heavily into their pass, and they're already the most pass-heavy team in the NFL. All three receivers are in my top 24, and Ladd McConkey and Keenan Allen (specifically Ladd) would vault significantly.

Brian Thomas Jr. has not finished above WR27 this year, but signs point to this being the breakout game his drafters all want. Seattle may be without Tariq Woolen, Devon Witherspoon, and Julian Love, and they just were eviscerated by the Tampa Bay passing game. Thomas is still 14th in the NFL in targets and 11th in air yards.

Matthew Golden is ascending. He has an elite 2.87 Yards Per Route Run over the past two games, and has a 41% air yards share over that span. He's not safe, especially with Christian Watson returning to the mix, but the upside is limitless against the Cincinnati defense. ... Romeo Doubs has a 90% snap share over the past two contests.

Calvin Ridley finally exploded and seems to have retaken the WR1 role. He has a golden matchup against the Raiders, who have allowed the second-most receptions and third-most yards to WRs. ... Tre Tucker is a low-floor, high-upside play in the same game whose outlook improves with Brock Bowers likely out again.

Tight End Rankings – Fantasy Football Week 6

If Ricky Pearsall and Jauan Jennings sit again (which it looks like), Jake Tonges is in TE1 territory and should be started. He caught seven of 11 targets in Week 5 and has scored in back-to-back games. Tampa has allowed the tenth-most FPPG to TEs. ... Mason Taylor has a 31% target share the last two weeks and has emerged as the Jets' #2 receiving option.

Darren Waller is back? Maybe. His snap rate went from 28% to 65% over two weeks, and Miami is desperate for receiving options. Start him if you need, but recognize the Chargers have been incredibly stout against TEs. ... I'm out on Mark Andrews this week unless Lamar Jackson returns. The Ravens offense looks like a dumpster fire without him.

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