🖥 TAP TO SAVE 50% WITH CODE THANKS
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

DraftKings Daily Fantasy Baseball Picks (4/5/21): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on 4/5/21. Euan Leith's MLB DFS analysis and sleepers for building optimal DFS rosters.

Happy Monday, RotoBallers! We kick off the first whole week of baseball with a seven-game featured slate on DraftKings. I would've loved to have the Orioles-Yankees contest here, but there will still be some great picks to add to our rosters as we kick off the week.

We get the surprising addition of Jacob deGrom to add to our options at pitcher tonight. It will be hard to get away from him with the lack of other aces on the mound. Of course, you can use his high roster percentage as leverage against him in tournaments, but you'll be hard-pressed to get in the money without him in cash games.

This article will provide you with my daily fantasy baseball lineup picks for DraftKings on 4/5/2021. The lineup will range from some of the elite players to mid-priced options and value plays. You can also check out today's FanDuel MLB DFS lineup picks and read more DFS advice and lineup picks for other sports too. It’s also important to monitor injury news and today's MLB starting lineups. If you have any questions or comments, contact me on Twitter.

Holiday Special! Save 50% on any Premium Pass using discount code THANKS. Win more with our DFS, Betting and Season-Long Premium Pass, get expert tools and advice from proven winners! GAIN ACCESS

 

DraftKings DFS Starting Pitchers

Jacob deGrom - P, NYM at PHI ($10,700)

With the Nationals and Mets series postponed over the week due to COVID-19 concerns, we have the option to play Jacob deGrom on a day where some teams are rolling out their third, fourth, or fifth starters. He's $1,900 more than Dustin May, and he is worth the premium on this seven-game schedule. In the shortened 2020, the 32-year old posted a career-high 38.8 percent strikeout rate and accumulated 104 strikeouts in 68 innings. DeGrom reached 200 IP in three straight seasons from 2017-2019, and last season he went at least six innings in eight of his 12 starts. New York is heavily favored (-220) in this season-opening contest and should put deGrom in a great spot to pick up the win.

Carlos Rodon - P, CWS at SEA ($6,700)

If we are going with a top-of-the-line ace like deGrom, we need to find a bargain-bin option if we want the chance to fit in some quality bats on Monday. Rodon is questionable at best, but the matchup is superb. The Mariners couldn't hit water if they fell out of a boat against lefties in 2020. Last season, they slashed .190/.279/.331 as a team versus southpaws and struck out 27.26 percent of the time. The White Sox scored 22 runs in four games over the weekend and will give Rodon plenty of run support to get the win as long as he gets through five innings.

Other Options: Trevor Williams vs. MIL ($8,300), Michael Wacha at BOS ($7,200)

 

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's RealTalkRaph on DraftKings - join in on the winning!

 

DraftKings DFS Infielders

James McCann - C, NYM at PHI ($3,700)

McCann will make his New York Mets debut on Monday against left-handed hurler Matt Moore and the Philadelphia Phillies. McCann will be batting near the bottom of a dangerous Mets lineup and have the righty-lefty advantage in his first game. It will put him in an excellent spot to make a good first impression. McCann has a .356 wOBA and 124 wRC+ versus southpaws compared to a .277 wOBA and 70 wRC+ against righties for his career.

Yuli Gurriel - 1B, HOU at LAA ($3,700)

I'll have a fair share of the Houston offense in my Monday lineups. Their lineup came out of the gates firing on all cylinders for 2021. They put up 35 runs on Oakland over four games. For context, they scored 25 runs in 10 games against the A's last season. Gurriel wasn't the most electric Astros over the four-game series, but he made his presence felt. The 36-year old went 7-for-15 with two runs, three RBI, a double, a home run while showing some plate discipline with four walks to one strikeout. He's batting fifth in a potent Astros lineup and should have plenty of chances to drive in some runs tonight.

Jake Cronenworth - 1B/2B, SD vs. SF ($3,400)

If you sat out the 2020 MLB DFS season, then you may have missed the phenom that is Jake Cronenworth. He exploded onto the baseball scene as a righty-smasher and was second in the National League Rookie of the Year voting. Last season, Cronenworth slashed .316/.382/.581 against righties and was, at times, a DFS cheat code. He slotted in as the sixth hitter during the first two games of the season but hit fifth on Saturday and, in a highly encouraging sign, second yesterday. If he can stay in the two-hole versus right handers (like Anthony DeSclafani tonight), Cronenworth's price won't be $3,400 for much longer.

Francisco Lindor - SS, NYM at PHI ($4,700)

I'm in on the Mets today. Lindor will be batting second ahead of a dangerous lineup in a hitter-friendly park and always has the platoon advantage with him being a switch hitter. I don't believe that Matt Moore will be throwing deep into this one, which means Lindor can get some looks against this Phillies bullpen. I realize they didn't give up a single run in their opening series versus the Braves, but I will need a little more of a sample size before I fade this unit. Lindor is priced down at the position for Monday. I also considered the red-hot Corey Seager ($5,600) but preferred the $800 in savings to spend elsewhere for tonight's slate.

Alex Bregman - 3B, HOU at LAA ($5,500)

Bregman delivered the goods on Friday with a home run and I'll look for him to come through again tonight. He'll have the righty-on-lefty matchup we love to exploit, and Quintana hasn't fared great versus right-handed batters in recent years. In 2019, Quintana allowed 19 home runs and a .290/.336/.466 slash line in 129.2 innings. As previously mentioned, the Houston offense is off to a red-hot start, and Bregman is right in the middle of the action.

 

DraftKings DFS Outfielders

Austin Meadows - OF, TB at BOS ($4,400)

Meadows is sitting at the top of the Tampa Bay offense so far in 2021, and the early returns look extremely promising. He batted first or second in every game during the opening weekend and produced a 3-for-11 line with two home runs, two RBI, and two walks. He'll face right-handed hurler Nick Pivetta in Fenway, and Meadows should excel. During his breakout 2019, the 25-year old slashed .298/.384/.576 against righties with 24 home runs. This game has an over/under of 9.5 runs, and there will be fireworks with some not-so-great pitching on the mound.

Jared Walsh - 1B/OF, LAA vs. HOU ($3,900)

Walsh was the walk-off hero for the Angels on Sunday night with a three-run bomb to clinch the series over the Chicago White Sox. He started the final two games of the weekend and went 4-for-8 with three runs, six RBI, a triple, and two home runs. Now, Walsh will welcome the Houston Astros and rookie pitcher Luis Garcia to Anaheim. He batted fifth in both those games and, if that sticks, he will be in a tremendous run-producing role. The Astros are a hot offense right now, but their starters didn't pitch more than six innings in any start. Their bullpen was used a lot and could give some promising late-inning opportunities to kick off the week.

Chas McCormick - OF, HOU at LAA ($2,000)

McCormick will be an exciting test of the DFS strategy for price vs. lineup slot. He hit ninth for the Astros in yesterday's game after Michael Brantley (wrist) sat out, and McCormick provided incredible returns on one swing of the bat. He went 1-for-3, but it was a three-run blast off Yusmeiro Petit in the sixth inning. He's $2,000, and it will give any DFS roster a leg up to empty their wallets at other spots in the lineup. Also, he'll be batting right ahead of Jose Altuve, Kyle Tucker, and Alex Bregman with a lefty on the mound. Sometimes the ninth spot isn't all that bad.



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!




MLB DFS News and Injury Alerts


More DFS Lineup Picks and Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Si Woo Kim

Closes 2025 With Strong Finish Among Putting Woes
Akshay Bhatia

Looks to Rebound in 2026 After Down Year Off the Tee
Brian Harman

2025 Season a Step Back Despite Spring Win
Sam Burns

' Elite Putting Headlines a Solid 2025 Season
Sepp Straka

Ends Stellar 2025 Campaign on a High Note
Robert MacIntyre

Closes Out a Steady 2025 Campaign
CFB

Chip Kelly Interviews for Georgia Tech Offensive Coordinator Job
CFB

Louisville Receiver Chris Bell has a Torn ACL
Davante Adams

in Good Spot for Week 15 Despite Hamstring Soreness
Devin Booker

Won't Play Against OKC
Jordan Poole

Considered Questionable for Thursday
Maxi Kleber

Sidelined for Wednesday's Matchup With Spurs
Dakota Mermis

to Miss a Month
Jake Evans

to Miss Thursday's Matchup
Elias Pettersson

Unlikely to Play Thursday
Min Woo Lee

Breaks Through to Win in Texas This Year
Nick Bjugstad

to Miss at Least Three Games
PGA

Alex Noren Wins Twice on European Tour This Year
Connor Hellebuyck

Returns to Practice
Pelle Larsson

Sidelined at Least One Week
John Carlson

Could Return Thursday
Andrei Kuzmenko

Sits as Healthy Scratch Wednesday
Wyndham Clark

has Up-and-Down 2025 Golf Season
CFB

Michigan Fires Head Coach Sherrone Moore
Dereck Lively II

to Undergo Season-Ending Foot Surgery
Corey Conners

Comes Close to Winning Again in Very Good 2025
Justin Rose

Turns Back the Clock in 2025
Mike Evans

Officially Questionable for Thursday Night Game
Geno Smith

Unlikely to Play in Week 15
CFB

Jim Knowles Expected to be Hired as Tennessee's Defensive Coordinator
Tyrone Tracy Jr.

"Good to Go" for Week 15
Harris English

Enjoys Solid Finish at Hero World Challenge
CeeDee Lamb

has "One or Two" Things Left to the Clear Concussion Protocol
Jayden Daniels

Commanders Not Shutting Down Jayden Daniels for the Year
CFB

Defensive Coordinator Jim Knowles Not Being Retained at Penn State
CFB

Indiana's Stephen Daley Done for Season After Post-Game Injury
Kyle Pitts Sr.

Carries Momentum and a Questionable Tag into TNF
Drake London

Won't Play on Thursday Night
Tyrone Tracy Jr.

Practicing Coming Out of the Bye Week
Garrett Wilson

Practice Window Still Hasn't Opened
Breece Hall

Out on Wednesday With Knee Soreness
Pete Alonso

Orioles Finalizing Five-Year Deal
Jayden Daniels

Ruled Out for Week 15
Cade Otton

Considered Doubtful for Thursday Night
Trey Benson

Will Not Be Activated in Week 15, Will Not Return in 2025
Mike Evans

has "Shown Everything he Needed to Show" to Return in Week 15
Nick Bjugstad

Injured Tuesday
Zach Ertz

Officially Placed on Injured Reserve
Frank Vatrano

Makes Early Exit Against Penguins
Colten Ellis

Enters Concussion Protocol
George Pickens

Cowboys Not Worried About George Pickens' Effort Level
Scott Wedgewood

Hurt During Shootout
Victor Hedman

Suffers New Injury Blow
Bobby McMann

Suspended for One Game
Jordan McLaughlin

Listed as Questionable for Wednesday
Maxi Kleber

Questionable Wednesday
Marcus Smart

Ready to Face Spurs Wednesday
Luguentz Dort

Returns From Three-Game Absence Wednesday
Alex Caruso

Set to Return Wednesday
Shai Gilgeous-Alexander

Available Wednesday
Isaiah Joe

Out for Third Consecutive Game
Isaiah Hartenstein

Not Ready to Return Wednesday
Devin Booker

Listed as Questionable for Wednesday
Victor Wembanyama

Remains Out Wednesday
Kyle Finnegan

Tigers, Kyle Finnegan Agree on Two-Year Deal
Bo Bichette

Red Sox Out on Bo Bichette For Now
Karl-Anthony Towns

Back in Action Against Toronto
Philip Rivers

has a "Very Real Chance" to Start in Week 15
Jason Zucker

Added to Injured Reserve
David Pastrnak

Set to Return Tuesday
Scott Wedgewood

Back Between the Pipes Tuesday
Evgeni Malkin

Lands on Injured Reserve
Jamal Shead

Available on Tuesday, Entering the Starting Lineup
Jordan Kyrou

Out Week-to-Week
Immanuel Quickley

Ruled Out on Tuesday Night
Thomas Harley

Returns to Stars Lineup Tuesday
Martin Necas

a Game-Time Call Tuesday
Jean-Gabriel Pageau

Available Tuesday
Philadelphia Phillies

Phillies Extend Manager Rob Thomson Through 2027 Season
Paolo Banchero

Remaining on a Minutes Limit Tuesday
Michael King

the Mets' Top Rotation Target?
Dru Smith

Will Be Available Tuesday
Pelle Larsson

Will Be Available Against Orlando
Ronald Acuña Jr.

Ronald Acuna Jr. Could Move Back to Leadoff Spot
CFB

Florida, Wisconsin Among Suitors for QB Transfer Kenny Minchey
DK Metcalf

"Moving in the Right Direction" for Week 15
CFB

Bryan Harsin, Justin Wilcox Candidates for Washington State Head Coach Job?
Edwin Díaz

Edwin Diaz Agrees to Deal With the Dodgers
Kyle Schwarber

Returning to Phillies on Five-Year Deal
Riley Leonard

Diagnosed With Grade 1 PCL Sprain
CFB

Ole Miss Hiring John David Baker as Offensive Coordinator
CFB

Ty Howle the Top Target for Virginia Tech Offensive Coordinator Job
A.J. Brown

Continues Dominant Stretch With 100 Yards in Monday Night Loss
Shohei Ohtani

to be Used More as Traditional Starting Pitcher Next Year
Yordan Alvarez

to Become Full-Time DH in 2026?
Mason Miller

Padres Plan to Keep Mason Miller in the Bullpen
Ranger Suárez

Orioles Interested in Signing Ranger Suarez
Anthony Volpe

Yankees Don't Expect Anthony Volpe to be Ready in April
Gerrit Cole

Targeting a Return in May/June
CFB

Heisman Trophy Finalists Announced on Monday
CFB

Anthony Hill Jr. Declaring for 2026 NFL Draft
CFB

Ryan Walters a Candidate for Tennessee Defensive Coordinator Job?
Rory McIlroy

Ends 2025 as the Year's Most Unburdened Player
Aaron Rai

Needs to Figure Out Putting Woes This Offseason
Jordan Spieth

Plays Better on Paper in 2025 Than Results Show
PGA

Chris Gotterup Needs to Find Better Touch and Consistency This Offseason
Hideki Matsuyama

Ends 2025 Season With a Bookend Victory
CFB

Tennessee Fires Defensive Coordinator Tim Banks
Scottie Scheffler

Comes Up Just Shy of Hero World Challenge Victory
Merab Dvalishvili

Drops A Decision At UFC 323
Petr Yan

Reclaims Bantamweight Title
Alexandre Pantoja

Era Ends With Gruesome Injury
Joshua Van

Becomes Second-Youngest UFC Champion
Brandon Moreno

Suffers His First TKO Loss
Brandon Moreno

Tatsuro Taira Becomes First Fighter To Finish Brandon Moreno
Henry Cejudo

Payton Talbott Retires Henry Cejudo
Henry Cejudo

Retires After UFC 323 Loss
Jan Blachowicz

Bogdan Guskov Vs. Jan Blachowicz Ends In A Majority Draw
Jan Blachowicz

And Bogdan Guskov Fight To Majority Draw
CFB

Texas RB CJ Baxter Entering Transfer Portal
San Francisco Giants

Jeff Kent Elected to Baseball Hall of Fame
Ketel Marte

Red Sox Interested in Trading for Ketel Marte
Kyle Schwarber

Pirates Make Four-Year Offer to Kyle Schwarber
CFB

Mississippi State, Rice Accept Bowl Bids as 5-7 Teams
CFB

Auburn, Florida State, Baylor Among Teams to Decline Bowl Bids
CFB

Rob Aurich Set to Become Nebraska's Defensive Coordinator
CFB

Notre Dame Opting Out of Postseason Amid College Football Playoff Exclusion
CFB

Kendal Briles a Candidate for South Carolina Offensive Coordinator Job
CFB

James Madison Playoff-Bound After Duke Wins ACC Title?
Jose A. Ferrer

Mariners Acquire Jose A. Ferrer from the Nationals
Harry Ford

Traded to the Nationals
Cody Bellinger

Drawing Interest From the Phillies
MacKenzie Gore

Will the Nationals Trade MacKenzie Gore?
Petr Yan

Looks To Reclaim Bantamweight Belt
Merab Dvalishvili

Set For His Fourth Title Defense
Joshua Van

Can Become The New Flyweight Champion
Alexandre Pantoja

Set For Fifth Title Defense At UFC 323
Tatsuro Taira

Looks To Win Back-To-Back Fights
Brandon Moreno

Searches For His Third Win In A Row
Payton Talbott

A Favorite At UFC 323
Henry Cejudo

Set For His Retirement Fight
Jan Blachowicz

Set To Open Up UFC 323 Main Card
Bogdan Guskov

Looks To Extend His Win Streak

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP