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DraftKings Daily Fantasy Baseball Picks (4/22/18): MLB DFS Lineups

Happy Sunday! We’ve got an 11-game featured slate on DraftKings today, one that excludes the west coast games. That still leaves us with Coors Field, Corey Kluber, and a lot of terrible, horrible starting pitchers.

It will be tough to fit the Klubot and the Coors Field bats in our lineup today, but there is plenty of value to be had in the middle and lower price range that will help us navigate through the Sunday slate. With so many bad pitchers on the mound today we won’t have to load up on Coors Field hitters to get some offense.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/22/18. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @ElliottBaasBB.

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DraftKings Starting Pitchers

Corey Kluber, CLE (@ BAL) - $12,800

There are a few good pitchers on the slate today, but none of them compare to Corey Kluber. Through his first four starts Kluber has a 30.3% strikeout rate, 1.52 ERA, 2.40 FIP, and .155 average against. Kluber also goes deep into games, having gone no less than 6.2 innings in every start thus far. When one pitcher stands above the rest it’s usually worth getting him in your lineup at all costs, at least in cash games. As a bonus this is a good matchup for Kluber. No team has struck out at a higher rate than the opposing Baltimore Orioles, who strike out 27.8% of the time collectively. The Orioles also have a .278 wOBA and 72 wRC+ against right-handed pitchers.

Luis Castillo, CIN (@ STL) - $7,200

Luis Castillo is better than his 6.75 ERA through four starts. His 3.62 xFIP and 3.76 SIERA suggest that. He also has a 51.3% strand rate, which is exceptionally unlucky even in a small sample size. Castillo also got a raw deal his last start out against the Brewers. He left with two earned runs over 6.2 innings, but reliver Cody Reed allowed two inherited runners to score, inflating Castillo’s final line. On the young season Castillo has actually increased his already impressive whiff rate. He currently has a 15.2% swinging strike rate on the season, suggesting he could improve on his 21.9% strikeout rate. Castillo is a great high upside SP2 to pair with Kluber.

 

DraftKings Infielders

C – Wilson Ramos, TB (vs. MIN) - $2,900

Phil Hughes is making his 2018 debut on Sunday, and we can’t let him go untouched. Last season Hughes had a 5.87 ERA, 5,41 FIP, and 2.01 HR/9. Hughes was once lauded for his control, but over the past few years his refusal to walk batters has gotten him punished in the strike zone. Hughes has allowed 52 homers in 268 innings since 2015, or 1.75 HR/9. Ramos is probably the best Ray to take advantage of Hughes. Ramos has a .188 ISO over the last two seasons and gives a power hitter at a generally weak position for a good price.

1B – Miguel Cabrera, DET (vs. KC) - $3,900

A rainout postponed Eric Skoglund’s start and ruined our Angels stack last week, and it’s time for revenge. When he finally made his start Skoglund got hammered for five runs on eight hits against the Blue Jays, which somehow lowered his career ERA from 9.53 to 9.43. Skoglund’s best attribute as a prospect was command, yet he has a 4.88 BB/9 over his career. He doesn’t have the stuff or the dominance to overcome such poor control. Miggy has bounced back nicely to begin the season, with an .830 OPS and 123 wRC+ on the young season. Even in a down year Miggy demolished left-handed pitchers. In 2017 he had a 149 wRC+ and .928 OPS against southpaws.

2B – Scooter Gennett, CIN (@ STL) - $3,100
For his career Gennett has been an above average hitter against righties, with a 109 wRC+ all time against them. During last year’s breakout he clobbered right-handers with a 133 wRC+, .261 ISO, and 23 of his 27 homers against them. He’ll face Cardinals righty Miles Mikolas, who has coughed up four homers in his first three starts this season. Gennett hasn’t homered yet this season, but he’s in a good position to catch one Sunday.

3B Jeimer Candelario, DET (vs. KC) - $3,400

We definitely want a little more exposure to Skoglund, and Candelario offers that at an affordable price. He has exploded over the last nine days, going 12-for-26 with three home runs during that span. Candelario is on fire and Skoglund is lighter fluid.

SS – Jean Segura, SEA (@ TEX) - $3,500

DraftKings pricing algorithm seems to hate Jean Segura. He is consistently under $4,000 despite back to back seasons with a wRC+ over 110, a batting average over .300, and more than 20 steals. Segura is off to a nice start this season, with a .303 average and three steals through 79 plate appearances. What really makes Segura a good play, despite the price, is his matchup against Martin Perez. Perez has been among the most hittable pitchers in the league thus far. He has a 13.14 ERA, 8.17 FIP, 1.00 K/BB, and 2.92 HR/9. He has the highest ERA and third highest FIP among pitchers with at least 10 innings this season. He may be achieving new lows, but Perez has never been good. Over 688.1 career innings Perez has a 4.59 ERA and 4.35 FIP.

 

DraftKings Outfielders

OF – Nelson Cruz, SEA (@ TEX) - $4,400

Remember all those reasons to play Jean Segura? The same apply to Nelson Cruz. He is Seattle’s best power hitter, and one of the elite power hitters in the game. Cruz is good against everybody, but he absolutely destroys left-handed pitchers. For his career he has .258 ISO and .392 wOBA against lefties. Globe Life Park was also the second most hitter friendly ballpark last season per ESPN park factors, so we are free to fade Coors with situations like the one in Arlington on Sunday.

OF – Mitch Haniger, SEA (@ TEX) - $3,700

Haniger has exploded out of the gate for five home runs and a .274 ISO in his first 73 plate appearances. Haniger had a .209 ISO and .360 wOBA last season in his first year as a big league regular. Like Segura, Haniger is underpriced given the matchup and in a great position on Sunday.

OF – Giancarlo Stanton, NYY (vs. TOR) - $4,900

Opposing starter Jaime Garcia may have a 3.86 ERA, but it comes with a 5.53 FIP and 2.20 HR/9. His 25.4% strikeout rate seems fluky given his 7.5% swinging strike rate. Despite a slump, Stanton still has a .233 ISO and four home runs in 83 plate appearances. Stanton is as big a home run threat as any player in baseball and is facing a pitcher that hasn’t been able to keep the ball in the yard consistently. Garcia has a 1.25 HR/9 over the last three seasons.

 

MLB DFS News and Injury Alerts

REAL-TIME FANTASY NEWS

Wyndham Clark

Looks to Continue Hot Streak at RBC Canadian Open
Sam Burns

is a DFS Must Have at RBC Canadian Open
Denny Hamlin

Goes from the Back to Victory at Michigan
Erik Jones

Earns his Best Finish of the 2026 Season So Far at Michigan
NASCAR

Bubba Wallace Moves up the Standings After Finishing Third at Michigan
Chase Elliott

Wrecks In the Final Stage at Michigan After Leading the Most Laps
Tyler Reddick

Crashes Out at Michigan After Winning A Stage
Bijan Robinson

Is Bijan Robinson's Dynasty Value Limited by Questionable Offensive Environment?
Woody Marks

Carries Buy-Low Appeal for Dynasty Managers Entering 2026
Antonio Williams

Poised for Dynasty Breakout in Washington?
Tyler Warren

Poised for Expanded Role in Indianapolis?
Seth McGowan

"Right in the Thick" of RB2 Battle in Indianapolis
Ashton Dulin

Poised to Win Starting Role in Indianapolis?
CFB

Brendan Sorsby Receives Injunction, Eligible for 2026 College Football Season
Gabriel Bonfim

Shines At UFC Vegas 118
Belal Muhammad

Suffers Third Consecutive Loss
Chris Rodriguez Jr.

Is Chris Rodriguez Jr. Falling Behind in Jaguars Running Back Battle?
Edmen Shahbazyan

Suffers Unanimous-Decision Loss
Edmen Shahbazyan

Brendan Allen Gets Unanimous-Decision Win Over Edmen Shahbazyan
Drew Allar

a Smart Stash in the Middle Rounds of Dynasty Rookie Drafts
Chris Olave

Still a High-Upside Dynasty Swing for the Risk Tolerant
Tom Nolan

Extends Win Streak
Farés Ziam

Fares Ziam Drops Decision At UFC Vegas 118
Jayden Higgins

"Going to Have a Great Year"
Jacoby Brissett

Expected to Report to Minicamp
Tarik Skubal

Dominates in Rehab Start, Return Appears Imminent
Mitchell Robinson

Available for Game 3
Chicago Bulls

Bulls Hire Alex Kaufman as Windy City Bulls General Manager
E.J. Liddell

Agrees to Two-Year Deal with Greek Club Aris
Konnor Griffin

is Looking at Extended Absence
Matas Buzelis

Will Play for Lithuania This Summer
Kenley Jansen

to Begin Rehab Assignment on Tuesday
Giannis Antetokounmpo

Has Concerns About Heat Roster If Traded to Miami
Casey Mize

to Make Rehab Start on Tuesday
Bobby Witt Jr.

Exits Early with Knee Soreness
Mitchell Robinson

Has Technical Foul Rescinded After Game 2 Win
Jarquez Hunter

Is it Time for Dynasty Managers to Move on From Jarquez Hunter?
Elijah Arroyo

Worth Buying Low on in Dynasty Formats?
Tre Tucker

Profiles as a Dynasty Sell-High Candidate Entering 2026
Jack Bech

Should Dynasty Managers Target Jack Bech as a Buy-Low Candidate?
Jaydon Blue

a Dynasty Buy-Low Candidate After Underwhelming Rookie Year?
Saquon Barkley

in Line for Larger Pass-Catching Role in 2026?
Max Fried

Nearing Return to Mound Work?
Karl-Anthony Towns

Eligible for Massive Extension
Isaiah Stewart

Could Draw Trade Interest
Chase Briscoe

Is Chase Briscoe Worth Rostering for DFS at Michigan?
Philadelphia 76ers

Jameer Nelson Promoted to Executive Vice President
Domantas Sabonis

Could be Traded This Summer
Ty Gibbs

Is Ty Gibbs Worth Rostering at Michigan This Week for DFS?
William Byron

Will Start at the Rear at Michigan After Unapproved Adjustments
NASCAR

Should DFS Managers Roster Bubba Wallace at Michigan?
Joey Logano

Is Joey Logano Worth Rostering In DFS Lineups for Michigan
Daniel Suarez

Might Have Tournament Appeal for Michigan DFS Lineups
Jonah Coleman

Is Jonah Coleman the Most Valuable Broncos Running Back in Dynasty Leagues?
William Carrier

Suffers Upper-Body Injury in Game 3 Versus Golden Knights
Darius Slayton

Will Darius Slayton Be Phased Out of New-Look Giants Offense?
Sebastian Aho

Records Two Assists in Losing Effort
Alex Lange

Earns Third Save, Quickly Entering Must-Roster Status
Keaton Mitchell

Can Keaton Mitchell Carve Out a Large Enough Role for a Fantasy Breakout?
Jordan Staal

Scores in Third Consecutive Game
Shea Theodore

Caps Multi-Point Effort With Game-Winning Goal Saturday
Kayshon Boutte

Will Attend Mandatory Minicamp
Denny Hamlin

Puts DFS Managers in Tough Spot for Michigan
Chase Elliott

Can Chase Elliott Get Back to His Old Ways at Michigan?
Chris Buescher

Looking for Another Solid Run at Michigan
Tomas Hertl

Collects Two Points in Overtime Win
Carson Hocevar

Qualifies Second, Seeking Redemption at Michigan
Ross Chastain

Can DFS Managers Trust Ross Chastain at Michigan?
Mitch Marner

Scores Fastest Hat Trick in Finals History
Brad Keselowski

Has Been Solid at Michigan
Will Smith

Scratched With Neck Stiffness, Expected to Return on Sunday
Auston Matthews

Maple Leafs Confident of Keeping Auston Matthews
Andrei Vasilevskiy

Wins Second Vezina Trophy
Brayden McNabb

Uncertain for Game 3 Against Hurricanes
Hunter Greene

Could Return Before the All-Star Break
Dylan Harper

Remains a Bright Spot for San Antonio
De'Aaron Fox

Shoots Well in a Loss to the Knicks
Victor Wembanyama

Scores 29 Points in Game 2 Loss
OG Anunoby

Anchors Knicks' Defense in Finals Game 2
Mikal Bridges

Helps Knicks Secure a Game 2 Victory
Karl-Anthony Towns

Records Another Finals Double-Double
Jalen Brunson

Overcomes Cold Night to Seal Game 2
Michael Harris II

Dealing With Back Tightness, Not Believed to be Serious
Byron Buxton

Suffers Shoulder Contusion After Colliding With the Wall
Sacramento Kings

Kings Want to Trade Their Larger Contracts
Chicago Bulls

Darius Acuff Jr. Works Out for Bulls
Jaime Jaquez Jr.

Could Get Traded
MIN

Marcus Johansson Returning to Europe
Thomas White

Likely to Miss Rest of Season With Shoulder Capsular Sprain
Mitchell Robinson

is Upgraded to Available for Game 2
Cole Caufield

Earns Lady Byng Trophy
Nick Suzuki

Lands Selke Trophy
Jose Altuve

Astros Reinstate Jose Altuve From the Injured List
CFB

Reed Harris Hoping to Fill Void in Arizona State Receiving Room
CFB

Nick Marsh Gearing Up for Breakout
CFB

Drew Mestemaker Looking to Catapult Oklahoma State Offense in 2026
CFB

Rocco Becht Brings Experience to New-Look Nittany Lions
CFB

Can Trey White, Adam Trick Keep Texas Tech's Defensive Front Elite?
CFB

Devon Dampier is Key to Success for Morgan Scalley in Year 1
Aaron Judge

Yankees Officially Place Aaron Judge on Injured List With Fractured Rib
Francisco Lindor

Expected to Return in "About a Couple Weeks"
Corey Seager

Rangers Activate Corey Seager From the Injured List
Gabriel Bonfim

Set For UFC Vegas 118 Main Event
Belal Muhammad

In Dire Need Of Win
Edmen Shahbazyan

An Underdog At UFC Vegas 118
Shayne Gostisbehere

Dishes Out Two Power-Play Assists in Comeback Win
Brendan Allen

Looks For His Third Win In A Row
Seth Jarvis

Ties Finals With Power-Play Goal
Mark Stone

Scores Sixth Playoff Goal in Overtime Defeat
Tom Nolan

Searches For His Fifth Consecutive Win
Mitch Marner

Records Two Assists in Game 2 Loss
Farés Ziam

Fares Ziam A Favorite At UFC Vegas 118
Brett Howden

Matches Franchise Record With Another Productive Outing
Brayden McNabb

Hospitalized After Taking Puck to Face
Aaron Judge

Diagnosed with Stress Fracture, Out 4-6 Weeks
Shohei Ohtani

has "Small" Blister, a "Non-Issue" for his Pitching Starts
Brent Rooker

Out on Thursday Due to Knee Soreness
Frederik Andersen

Hurricanes Retain Confidence in Frederik Andersen
Vincent Trocheck

Maple Leafs Interested in Vincent Trocheck
Dylan Larkin

Requests Trade From Red Wings
Corey Seager

Expected to Return This Weekend
Lucas Erceg

Royals to Mix and Match in Ninth With Lucas Erceg Struggling
Rickie Fowler

Looks To Continue Resurgent Season At Memorial
CFB

Can Eric Singleton Jr. Fully Break Out at Third School?
CFB

Katin Houser Steps into QB1 Role for Illinois
CFB

Savion Hiter an Immediate Impact Freshman for Michigan
CFB

Isaiah Horton Set to Take Over KC Concepcion's Role
CFB

UCLA Transfer Karson Gordon Signs with Austin Peay
CFB

Will Muschamp Bringing New Intensity to Texas Practices
Gary Woodland

Brings Boom-or-Bust Potential to Memorial
Jordan Spieth

Still Searching for a Breakthrough
Alex Smalley

Brings Elite Form to Memorial Tournament
Justin Rose

Looks to Recapture Memorial Tournament Success
Cameron Young

Looks to Get Back to His Contending Ways at Murifield Village
Chris Gotterup

Needs to Find Fairways at Muirfield Village
Si Woo Kim

Looks to Stay Hot at Memorial Tournament
Matt Fitzpatrick

Positioned for Success at Muirfield Village
Keegan Bradley

Looking for Another Strong Finish at Muirfield
Justin Thomas

is an Exciting Play This Week in Ohio
Scottie Scheffler

Looks to Win Memorial Tournament for Third Consecutive Year
Rory McIlroy

Looking for Better Performance at Muirfield Village
Russell Henley

Coming to Ohio on the Heels of Latest Victory
Tommy Fleetwood

Looking for Better Iron Play at Memorial Tournament
Patrick Cantlay

Looks to Continue Dominance at Muirfield Village
Ludvig Aberg

a Great Fit for Muirfield Village
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF