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DraftKings Daily Fantasy Baseball Picks (4/22/18): MLB DFS Lineups

Happy Sunday! We’ve got an 11-game featured slate on DraftKings today, one that excludes the west coast games. That still leaves us with Coors Field, Corey Kluber, and a lot of terrible, horrible starting pitchers.

It will be tough to fit the Klubot and the Coors Field bats in our lineup today, but there is plenty of value to be had in the middle and lower price range that will help us navigate through the Sunday slate. With so many bad pitchers on the mound today we won’t have to load up on Coors Field hitters to get some offense.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/22/18. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @ElliottBaasBB.

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DraftKings Starting Pitchers

Corey Kluber, CLE (@ BAL) - $12,800

There are a few good pitchers on the slate today, but none of them compare to Corey Kluber. Through his first four starts Kluber has a 30.3% strikeout rate, 1.52 ERA, 2.40 FIP, and .155 average against. Kluber also goes deep into games, having gone no less than 6.2 innings in every start thus far. When one pitcher stands above the rest it’s usually worth getting him in your lineup at all costs, at least in cash games. As a bonus this is a good matchup for Kluber. No team has struck out at a higher rate than the opposing Baltimore Orioles, who strike out 27.8% of the time collectively. The Orioles also have a .278 wOBA and 72 wRC+ against right-handed pitchers.

Luis Castillo, CIN (@ STL) - $7,200

Luis Castillo is better than his 6.75 ERA through four starts. His 3.62 xFIP and 3.76 SIERA suggest that. He also has a 51.3% strand rate, which is exceptionally unlucky even in a small sample size. Castillo also got a raw deal his last start out against the Brewers. He left with two earned runs over 6.2 innings, but reliver Cody Reed allowed two inherited runners to score, inflating Castillo’s final line. On the young season Castillo has actually increased his already impressive whiff rate. He currently has a 15.2% swinging strike rate on the season, suggesting he could improve on his 21.9% strikeout rate. Castillo is a great high upside SP2 to pair with Kluber.

 

DraftKings Infielders

C – Wilson Ramos, TB (vs. MIN) - $2,900

Phil Hughes is making his 2018 debut on Sunday, and we can’t let him go untouched. Last season Hughes had a 5.87 ERA, 5,41 FIP, and 2.01 HR/9. Hughes was once lauded for his control, but over the past few years his refusal to walk batters has gotten him punished in the strike zone. Hughes has allowed 52 homers in 268 innings since 2015, or 1.75 HR/9. Ramos is probably the best Ray to take advantage of Hughes. Ramos has a .188 ISO over the last two seasons and gives a power hitter at a generally weak position for a good price.

1B – Miguel Cabrera, DET (vs. KC) - $3,900

A rainout postponed Eric Skoglund’s start and ruined our Angels stack last week, and it’s time for revenge. When he finally made his start Skoglund got hammered for five runs on eight hits against the Blue Jays, which somehow lowered his career ERA from 9.53 to 9.43. Skoglund’s best attribute as a prospect was command, yet he has a 4.88 BB/9 over his career. He doesn’t have the stuff or the dominance to overcome such poor control. Miggy has bounced back nicely to begin the season, with an .830 OPS and 123 wRC+ on the young season. Even in a down year Miggy demolished left-handed pitchers. In 2017 he had a 149 wRC+ and .928 OPS against southpaws.

2B – Scooter Gennett, CIN (@ STL) - $3,100
For his career Gennett has been an above average hitter against righties, with a 109 wRC+ all time against them. During last year’s breakout he clobbered right-handers with a 133 wRC+, .261 ISO, and 23 of his 27 homers against them. He’ll face Cardinals righty Miles Mikolas, who has coughed up four homers in his first three starts this season. Gennett hasn’t homered yet this season, but he’s in a good position to catch one Sunday.

3B Jeimer Candelario, DET (vs. KC) - $3,400

We definitely want a little more exposure to Skoglund, and Candelario offers that at an affordable price. He has exploded over the last nine days, going 12-for-26 with three home runs during that span. Candelario is on fire and Skoglund is lighter fluid.

SS – Jean Segura, SEA (@ TEX) - $3,500

DraftKings pricing algorithm seems to hate Jean Segura. He is consistently under $4,000 despite back to back seasons with a wRC+ over 110, a batting average over .300, and more than 20 steals. Segura is off to a nice start this season, with a .303 average and three steals through 79 plate appearances. What really makes Segura a good play, despite the price, is his matchup against Martin Perez. Perez has been among the most hittable pitchers in the league thus far. He has a 13.14 ERA, 8.17 FIP, 1.00 K/BB, and 2.92 HR/9. He has the highest ERA and third highest FIP among pitchers with at least 10 innings this season. He may be achieving new lows, but Perez has never been good. Over 688.1 career innings Perez has a 4.59 ERA and 4.35 FIP.

 

DraftKings Outfielders

OF – Nelson Cruz, SEA (@ TEX) - $4,400

Remember all those reasons to play Jean Segura? The same apply to Nelson Cruz. He is Seattle’s best power hitter, and one of the elite power hitters in the game. Cruz is good against everybody, but he absolutely destroys left-handed pitchers. For his career he has .258 ISO and .392 wOBA against lefties. Globe Life Park was also the second most hitter friendly ballpark last season per ESPN park factors, so we are free to fade Coors with situations like the one in Arlington on Sunday.

OF – Mitch Haniger, SEA (@ TEX) - $3,700

Haniger has exploded out of the gate for five home runs and a .274 ISO in his first 73 plate appearances. Haniger had a .209 ISO and .360 wOBA last season in his first year as a big league regular. Like Segura, Haniger is underpriced given the matchup and in a great position on Sunday.

OF – Giancarlo Stanton, NYY (vs. TOR) - $4,900

Opposing starter Jaime Garcia may have a 3.86 ERA, but it comes with a 5.53 FIP and 2.20 HR/9. His 25.4% strikeout rate seems fluky given his 7.5% swinging strike rate. Despite a slump, Stanton still has a .233 ISO and four home runs in 83 plate appearances. Stanton is as big a home run threat as any player in baseball and is facing a pitcher that hasn’t been able to keep the ball in the yard consistently. Garcia has a 1.25 HR/9 over the last three seasons.

 

MLB DFS News and Injury Alerts

REAL-TIME FANTASY NEWS

Julian Champagnie

Notches 22 Points With Four Triples Tuesday
Trevor Etienne

Could Still Find Dynasty Relevance After Quiet Rookie Season
Stephon Castle

Leads Spurs in Scoring Tuesday Night
Rickie Fowler

Looks to Regain Momentum at Colonial
Victor Wembanyama

Struggles in Game 5 Loss to Thunder
Bam Knight

Dynasty Value Has Run Dry in Crowded Running Back Room
Alex Caruso

a Difference-Maker Again in Game 5
Pierceson Coody

Looking to Stay Hot at Colonial
Jared McCain

Produces 20 Points in First Playoff Start
Mac Jones

and 49ers Agree to a Revised Contract
Shai Gilgeous-Alexander

Scores Game-High 32 Points in Game 5 Win
Martin Necas

Collects an Assist in Game 4 Loss to Golden Knights
Gabriel Landeskog

Scores Only Avalanche Goal in Season-Ending Loss
Carter Hart

Finishes Series-Clincher With 20 Saves
Dylan Coghlan

Continues Unlikely Success Story
Cole Smith

Scores Series-Clincher Tuesday Night
Mark Stone

Nets Another Goal as Golden Knights Finish Off Avalanche
Ludvig Aberg

Looking to Exchange Momentum for a Victory in Fort Worth
Stephan Jaeger

Trending Upward as PGA Heads to Fort Worth
Max Homa

Comes Off Awful Putting Performance at PGA Championship
Tony Finau

Faces Different Test at the Colonial
Robert MacIntyre

Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Tory Horton

Could Do Some Stuff "Toward the End of Spring"
Patrick Mahomes

Takes Part in First OTA Practice on Tuesday
Los Angeles Chargers

Derwin James Jr. Becomes Highest-Paid Safety for the Second Time in his Career
Chris Brooks

Emerging as Top Handcuff to Stash?
MarShawn Lloyd

Sees Short-Term Value Soar
Jared McCain

Moves into Starting Five
Boston Celtics

Joe Mazzulla Wins Coach of the Year
Jalen Williams

is Ruled Out for Game 5 on Tuesday
Bucky Irving

is Expected to be Ready for Training Camp
Zion Williamson

to See More Versatile Role
Parker Washington

Jaguars Think Parker Washington Can Replicate Second-Half Production
Cleveland Cavaliers

Kenny Atkinson to Remain Cavaliers Head Coach Next Season
Josh Jacobs

Arrested on Five Charges, Booked Into Jail
Claude Giroux

Planning to Return for 20th NHL Campaign
Josh Sweat

Cardinals Receiving Trade Calls on Josh Sweat
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Tetairoa McMillan

Working With the Training Staff on Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
Nathan MacKinnon

Will Suit Up Tuesday
Jerome Ford

Is it Time for Dynasty Managers to Drop Jerome Ford?
John Metchie III

Poised for Breakout Season with New Team in 2026?
Jalen Milroe

Is Jalen Milroe Still Worth Stashing in Dynasty Formats Entering 2026?
Kyle Pitts Sr.

Is Kyle Pitts Sr. a Dynasty Sell-High Candidate Coming Off Breakout Season?
Nico Collins

Agrees to Contract Adjustment with Texans
Chris Brooks

Carries Buy-Low Dynasty Appeal into 2026
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
NFL

NFL Unlikely to Expand to 18 Regular-Season Games by 2027
Sahith Theegala

Searching For Swing at Charles Schwab Challenge
Lamar Jackson

in Attendance at OTAs This Week
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Evan Mobley

Finishes Season-Ending Loss With 15 Points
James Harden

Wants to Stay in Cleveland
Donovan Mitchell

Remains Committed to Cavaliers
Mikal Bridges

Cools Off in Game 4 Against Cavaliers
OG Anunoby

Active on Both Ends in Blowout Win
Karl-Anthony Towns

Leads Knicks in Scoring During Series-Clincher
Jalen Brunson

Named Eastern Conference Finals MVP
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
Shayne Gostisbehere

Scores First Postseason Goal
Taylor Hall

Ends Four-Game Goal Drought
Andrei Svechnikov

Scores Game 3 Winner in Overtime
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dennis Schröder

Dennis Schroder is Ruled Out for Game 4 on Monday
Michael Porter Jr.

Nets Could Trade Michael Porter Jr.
Ajay Mitchell

is Ruled Out for Game 5
Valeri Nichushkin

Nathan MacKinnon, Valeri Nichushkin Uncertain for Game 4
Oliver Kapanen

Sitting as Healthy Scratch Monday
Max Domi

Out Indefinitely Due to Offseason Surgery Complications
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Robby Snelling

Will Undergo Tommy John Surgery
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF