NFL Week 11 Predictions: Picks and Analysis for Every Football Game

November 16, 2025

Free NFL betting picks for every Week 11 matchup in 2025. Expert analysis and predictions for NFL Week 11. Who should you bet in Week 11? Analysis for every game on the slate.

Week 11 of the NFL season offers a combination of heavyweight matchups and divisional clashes. There are several pivotal games on this week's slate.

Most notably, we have some serious divisional battles in both conferences, with the Rams taking on the Seahawks in the NFC West, as well as the Chiefs and Broncos meeting in Mile High.

Through the good, bad, and ugly, we'll dive into all the juicy spots on this slate, as we go through every Week 11 game in this article, offering picks, predictions, and analysis for each and every one. Thanks for joining us here at RotoBaller; let's dive in!

New England Patriots 27, New York Jets 10 (Thursday)

Don't look now, but the New York Jets have won two football games in a row. That winning streak is in peril in Week 11, as Gang Green heads to Foxboro on Thursday night to face their longtime AFC East rival, the New England Patriots.

Time to write the next chapter in this storied rivalry #TNFonPrime pic.twitter.com/QRpr0XCIq6

— NFL on Prime Video (@NFLonPrime) November 13, 2025

The Pats have been on their own impressive run, with last week's victory over Tampa Bay marking their seventh straight win. Second-year quarterback Drake Maye looks every bit the part of a franchise cornerstone and will feast on a Jets secondary that ranks dead last in the NFL in passing yards allowed per game, while New England's defense should have no issues containing a New York offense that's expected to remain without Garrett Wilson in Week 11.

Miami Dolphins 24, Washington Commanders 20 (Madrid)

Part of the NFL's International Series, this matchup takes place Sunday morning in Madrid. Let me be the first to apologize to Spain for this uninspired matchup of underachieving squads.

The Commanders head overseas the losers of five straight - with four of those losses by 20-or-more points. The dynamic duo of Jayden Daniels and Terry McLaurin are expected to remain sidelined for this one, so it's tough to envision things getting much better, even against a Dolphins team that enters with an equally-bad 3-7 record.

Miami is coming in off a huge upset win over the Bills in Week 10, and Mike McDaniel's bunch has now won two of their last three. De'Von Achane has been a dual-threat dynamo for Miami, and should slice and dice a Washington defense that's 29th or worse in the NFL in total yards, passing yards, and points allowed per game.

Los Angeles Chargers 23, Jacksonville Jaguars 21

Fresh off a beatdown of the Steelers on Sunday night, Jim Harbaugh's Chargers must travel cross country for a 1:00 ET kickoff against the Jaguars, something that's never an easy task for a West Coast club. The Bolts have struggled in similar spots this season, losing in New York to the Giants in Week 4, as well as struggling early against both the Dolphins and Titans.

Will the Jaguars be able to capitalize on their home-field advantage? That's a tough question to answer for a team that's now lost three of their last four following last week's choke job in Houston. Jacksonville coughed up a 19-point fourth-quarter lead against the Texans in Week 10 while being held to just 213 total yards.

Trevor Lawrence and the offense have largely failed to fire over the past month, and enter this matchup still dealing with injuries to key players. I don't see them turning things around against an L.A. defense that's been very good statistically.

Buffalo Bills 24, Tampa Bay Bucs 23

While this matchup has all the trappings of a potential shootout, I'm gonna pump the brakes on this one breaking the scoreboard, as snow & wind are currently being forecast for Orchard Park.

Bucs WR Bucky Irving (7) and WR Chris Godwin (gray sweats) prepare to practice Thursday. Both were limited Wed but could play vs Bills. pic.twitter.com/FmZ43Mrb9u

— Rick Stroud (@NFLSTROUD) November 13, 2025

Both of these quality teams will be eager to rebound from Week 10 losses - Tampa's coming at home to New England and Buffalo's in more shocking fashion at Miami. Buffalo's secondary is allowing the league's third-fewest passing yards per game, look for them to slow down Baker Mayfield and Tampa's injury-depleted receiving corps enough for the Bills to snag a bounce-back win at home this week.

Chicago Bears 27, Minnesota Vikings 24

It hasn't always been pretty, but the Bears enter this NFC North clash the winners of six of their last seven. A Week 10 rally past the Giants was just the latest in a string of Chicago's dramatic victories. They'll now be tasked with a Vikings squad that beat them on their home turf in the season opener.

Despite a shocking Week 9 win over the Lions in Detroit, the Minnesota offense still feels like a work in progress with J.J. McCarthy under center. McCarthy tossed to interceptions against Baltimore in a the team's Week 10 loss, and while he should find easier sledding against a soft Bears defense, he remains an unpredictable factor for Kevin O'Connell's group.

Green Bay Packers 23, New York Giants 17

It's been a week full of news for the G-Men, who fired head coach Brian Daboll and named Jameis Winston as their Week 11 starter with Jaxson Dart expected to be sidelined from a concussion. While we sometimes see a post-firing bump for NFL teams, I don't know if that will be the case with a Giants squad that had remained largely competitive with Daboll at the helm.

The greatest city in the world!! 🎶 pic.twitter.com/qt2qzhOD9k

— New York Giants (@Giants) November 12, 2025

Packers head coach Matt LaFleur might be feeling some heat of his own, as the Packers dropped their second straight game in Week 10. While a loss to the defending Super Bowl champs isn't a shocker, many outsiders are starting to wonder when/if the 5-3-1 Packers are going to find their groove. Look for heavy doses of Josh Jacobs in this matchup against a New York defense that's being gashed for an average of 152 yards per game on the ground.

Houston Texans 20, Tennessee Titans 10

With C.J. Stroud sidelined, the Texans and quarterback Davis Mills overcame a 19-point, fourth-quarter deficit to defeat the Jaguars at home last week. Those types of heroics shouldn't be need in Week 11 against an abysmal Titans squad who comes in off their bye at 1-8.

While Cam Ward has displayed some flashes of why he was the top overall pick of the 2025 NFL Draft, the organization around him appears to be in shambles on and off the field. Tennessee ranks dead last in the league in total yards and points per game. They have little chance of finding success against a Texans defense that's one of the NFL's best units.

Atlanta Falcons 21, Carolina Panthers 20

In the "Anything Could Happen" matchup of the week, we get two NFC South squads who have been among the NFL's most unpredictable teams in 2025. Carolina shockingly drubbed Atlanta 30-0 when they met in Week 3. The Panthers have continued their Jekyll & Hyde ways by beating Green Bay at Lambeau and losing to the Saints at home over the past two weeks.

The results haven't been any cleaner for the Falcons, who followed an inexplicable home loss to Miami with hard-fought defeats at the hands of the Pats and Colts over the last two weeks. Who knows which version of these squads show up this week, but I'll give the slight edge to Atlanta in Mercedes-Benz Stadium.

Pittsburgh Steelers 28, Cincinnati Bengals 24

I'll give the Bengals credit...at least they ain't boring. A wild three-week stretch that included a win over this very Steelers team and last-minute losses to the Jets and Bears culminated with a bye for Cincy last week. As the Bengals hope for Joe Burrow's return, they now travel to Pittsburgh in what amounts to a must-win game in order to keep their season alive.

The Steelers offense and Aaron Rodgers were pitiful in a Sunday night loss to the Chargers last week. However, the Bengals abysmal defense has been an elixir for opposing offenses. Cincinnati ranks dead last in the NFL in total yards, rushing yards, and points allowed per game. Even though Pittsburgh feels like a paper tiger, they should still be able to take care of business at home this week.

Seattle Seahawks 24, Los Angeles Rams 21

Two red-hot NFC West squads are set to square off in a Week 11 showdown. The 7-2 Seahawks travel down the coast to face the 7-2 Rams in what could very well be a playoff preview, as well as a key game for postseason seeding purposes.

The line favoring the Rams has gone up as high as -3.5 points. Money is coming in on LA.

This might be the last game the Seahawks are underdogs the rest of the season. pic.twitter.com/ihu3801qJ6

— Brian Nemhauser (@hawkblogger) November 13, 2025

Matthew Stafford is playing at an MVP-caliber level, but he'll face a young up-and-coming defense in Seattle. Mike Macdonald's unit is capable of getting Stafford off his spots, while Sam Darnold and this revamped passing attack is capable of finding some success against a good Rams defense. Look for a tight game between these two quality football teams.

Kansas City Chiefs 20, Denver Broncos 17

On the heels of a gut-wrenching loss at Buffalo and a bye week, the Chiefs must now travel to Mile High to face a dangerous divisional rival in the Broncos. If KC want's to claim its 10th consecutive AFC West title, this game can be considered a must win for Patrick Mahomes and company.

They'll face a smothering Denver defense that's one of the best units in the NFL. The Broncos will be without superstar cornerback Patrick Sartain, as well as linebacker Alex Singleton. Expect Andy Reid to put this game in the hands of Mahomes, as well as KC's rock-solid defense, who should be able to disrupt Bo Nix in what's been an uneven second season for him.

Baltimore Ravens 28, Cleveland Browns 16

It wasn't that long ago that the Ravens were sitting at 1-5 and seemed to be a team on the brink of a lost season. However, a bye week coupled with the return of Lamar Jackson and multiple defensive players to the lineup, has enable the Ravens to run off three straight wins to pull within one game of .500.

They'll look to reach 5-5 against the Cleveland Browns, a squad that they dismantled 41-17 in Week 2. While the Browns' defense is tough enough to help them hang around in this one, they are no match for a healthy Baltimore squad.

Philadelphia Eagles 27, Detroit Lions 24 (Sunday Night)

The Lions offense looked rejuvenated in last week's 44-22 win over the Commanders. We can probably attribute a lot of that success to the fact that Dan Campbell quietly resumed offensive play-calling duties. While Campbell calling the shots should prove to be an improvement for the Detroit attack, they face a stiff test in a Sunday night matchup with the Eagles at Lincoln Financial Field.

Now that it is Lions week, here are some fun facts about the series:

- Nick Sirianni is 2-0 vs Dan Campbell as the Eagles scored an average of 41ppg

- Since 1990, Eagles are 9-4 vs the Lions

- Since 2000, these teams have only played in Philly 4 times and it is 2-2 with the… pic.twitter.com/opWYKb6yzC

— Fly Eagles Fly Bets (@Fly_EaglesBets) November 13, 2025

Philly comes in off holding the Packers to just 7 points in a Monday Night Football win at Lambeau. The defending Super Bowl champs have tightened the screws defensively of late, allowing an average of just over 16 points over their last three games. While the Eagles offense has failed to fully take flight, they are still capable of explosive scoring outbursts.

Look for Jalen Carter and this trending Philly defense to take advantage of Detroit's injuries along the offensive line in this potential NFC title game preview.

Dallas Cowboys 35, Las Vegas Raiders 21 (Monday Night)

We close out the Week 11 slate with a Monday night matchup between the high-octane Cowboys and the scuffling Raiders. Dallas comes into this game with heavy hearts following the death of Marshawn Keeland during the team's bye week. Despite the tragic loss, look for the 'Boys to play inspired football in a primetime spot.

The Cowboys field one of the worst defenses in the NFL, but they should still be able to relatively contain a struggling Geno Smith. The Dallas offense led by Dak Prescott, CeeDee Lamb, and George Pickens should outpace the Silver & Black handily.

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