Jamie Calandro's Week 10 Fantasy Football Rankings - The Industry's Top 10 Accuracy Ranker

Fantasy football Week 10 rankings for RB, WR, TE, QB from the No. 6 most accurate ranker in 2025, Jamie Calandro. Read his fantasy rankings analysis and outlooks.

RotoBaller writer Jamie Calandro shares his Week 10 fantasy football lineup rankings for RB, WR, TE, and QB. After eight weeks, Jamie is still #6 on the leaderboard among the most accurate rankers in the industry -- and is here today to bring you his Week 10 rankings! This rankings article also includes rankings analysis that will hopefully help you make some tough decisions when it comes to sit/start. Jamie is also on X @jac3600 and in our RotoBaller Discord channel, answering questions.

Regular starting options are included to highlight that some of your must-start players have a good chance of supplying winning totals. Much of the analysis helps fantasy players make the tough decisions between two or more similarly valued players.

The rankings are updated as news breaks until the full slate begins on Sunday. Following the positional advice below, you can consult the player rankings tables. The fantasy football lineup rankings analysis is based on half-PPR scoring rules.

Quarterback Rankings – Fantasy Football Week 10

Despite having absolutely no help at WR (and an injured OL), Jaxson Dart is fantasy's QB3 over the last six weeks. He's giving Giants fans optimism we haven't had before, and he is a must-start against a Bears defense giving the second-most yards per play.

Marcus Mariota will take over as the signal-caller for the Commanders. Detroit is favored by eight points on the road, but the game still shows an O/U of 49.5 points. Mariota should be forced to throw a ton in this game, and he was highly efficient replacing Daniels earlier in the year (9.8 YPA).

You're still starting Baker Mayfield even with his depleted cast of characters. This NE/TB game screams shootout. This is actually a tough matchup for Sam Darnold, as Arizona has allowed the ninth-fewest FPPG to QBs and only 6.5 YPA. I trust him with Jaxon Smith-Njigba as his main man, but temper expectations.

J.J. McCarthy is usable as a desperation bye-week QB, but don't expect the world from him. The Minnesota offense has been very scattered. I'm not touching Dillon Gabriel or Justin Fields in the dysfunctional bowl, although Gabriel's matchup is helped by the Jets trading away their two best defensive players this week.

Running Back Rankings – Fantasy Football Week 10

D'Andre Swift and Kyle Monangai are both on the injury report for this week, and their status is critical for the week. The Giants are getting obliterated by the run, allowing 6.2 YPC and the second-most FPPG to RBs. Both are playable as is, but if one misses, the other becomes a top-10 (or even top-5) back.

The Jets were getting decked for the ninth-most FPPG allowed to RBs with Quinnen Williams. He's gone now, and it's open season. Quinshon Judkins should absolutely blast through that line. TreVeyon Henderson looks like he's what we want him to be now. With Rhamondre Stevenson out, Henderson played 75% of snaps with a 22% target share. Start him with confidence.

Devin Singletary outsnapped, outcarried, and outplayed Tyrone Tracy Jr. in Week 9. Neither Giants RB is startable this week in what looks like a true 50/50 split. The same applies to the Texans' backfield, as Nick Chubb and Woody Marks vacillate weekly. Jacksonville has allowed the eighth-fewest FPPG to RBs.

In a similar vein, Emari Demercado and Zonovan Knight split duties for the Cardinals, while Michael Carter is off the radar completely. It's an absolutely brutal matchup against Seattle, but Demercado can be started in a pinch due to his superior role in the receiving game.

Kenneth Walker and Zach Charbonnet continue to be a nightmare for fantasy owners, but Walker's outlook shone a bit more as he had the edge in scoring-zone usage. Both are FLEX playable against Arizona, but cap each other's ceiling.

Believe it or not, Alvin Kamara is a sit now. Devin Neal has taken over the passing game role, which was always Kamara's floor. He hasn't topped 100 scrimmage yards since Week 2, and hasn't even topped 50 since Week 6. David Montgomery is still the RB23 in fantasy despite Jahmyr Gibbs' presence. He's always startable in that Detroit offense.

Wide Receiver Rankings – Fantasy Football Week 10

Chris Olave's volume is fair to question after he only got four targets from Tyler Shough. I'd still start him in full PPR leagues, but it's scary to trust any Saints. Tetairoa McMillan's box scores suffer because Carolina simply doesn't pass anymore. He's still the WR1 and is startable, but keep in mind the ceiling isn't there.

Parker Washington has 19 targets over his last two games, and his tendency to line up primarily in the slot means he should avoid the stout CBs of Houston. He's vaulted up the rankings this week.  Tez Johnson is an interesting bye-week play as Emeka Egbuka figures to draw the coverage of Christian Gonzalez.

The Bears scored 47 points, and Rome Odunze did not log a single target. Woof. I'm still starting him against a Giants secondary that has allowed the fifth-most FPPG to WRs. D.J. Moore is also startable after logging 72 and 73 yards in back-to-back games. Wan'Dale Robinson is the only trustworthy Giant. He has an elite 98% snap share since Malik Nabers went down.

Kayshon Boutte's injury does not render Kyle Williams (his direct replacement) startable. He only got one target and didn't catch it. I want to like Jerry Jeudy with Sauce Gardner traded, but his season-high is 66 yards, and he hasn't scored yet this year. If you're absolutely beyond desperate, this is theoretically his best matchup in a while.

Even in the Eagles' run-first offense, DeVonta Smith should never be on your bench. He's quietly the WR14 in FPPG and leads the team in deep targets, along with a 26% target share. It's fair to even call him the WR1 in Philadelphia now. Keenan Allen is rapidly ceding usage to Tre' Harris. Game script is everything with these two, as Harris should continue to thrive when L.A. is ahead, while Allen needs them to be trailing to achieve his volume threshold.

Tight End Rankings – Fantasy Football Week 10

Hunter Henry's targets have been less consistent this season, but he still sports the highest target share from Drake Maye since Maye took over as QB. Boutte's injury helps. New England has allowed the seventh-most FPPG to TEs, and Cade Otton is a legit TE1 with all the injuries to Tampa Bay.

I really want to promote the Colston Loveland breakout, but Cole Kmet should be back. We have to chill, unfortunately.

Harold Fannin Jr. leads the Browns in targets from Gabriel and is the TE11 in that span. He's a solid play even in a gross game.

Mark Andrews and Isaiah Likely cannibalize each other. Neither are feel-good starts, but Andrews has the TD upside. He's OK if need be, as the Ravens have a team total of 27 points.

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