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Key Starters and Tough Calls - Lineup Spotlights for Fantasy Football Week 1

Josh Jacobs - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Scott breaks down his fantasy football lineup starts/sits for Week 1 (2022). He spotlights key NFL players to start, and tougher lineup start/sit decisions.

Below you will find some of my favored choices and players to go with when dealing with challenging lineup decisions in Week 1. These selections are based on my Premium Weekly Lineup Rankings, available as part of the RotoBaller NFL Premium Pass. Enter promo code KING at checkout for a discount and get access to my ranks in all formats, plus a full roster of tools and analysis for the 2022 fantasy football season.

We feature players that you should lean to in tough calls, yet guys who may exceed expectations this week are also highlighted, so you can feel even more confident about starting them. In some cases, we will simply confirm for you that a good lineup decision was already made.

Skill position analysis here is based on my PPR rankings.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Running Backs - Fantasy Football Week 1

Chase Edmonds

Chase Edmonds had a career-high 903 scrimmage yards in 2021. Now he will get an opportunity to be a heavily featured running back for the first time in his career. Bill Belichick can always scheme up a good game plan, but the Patriots’ front seven doesn’t scare opponents anymore.

Edmonds should be busy enough as a runner and receiver this week to be a good flex play. The Dolphins have a lot of speed on offense and Edmonds is one of their notable playmakers in that regard.

Josh Jacobs

Josh Jacobs rushed for 132 yards and a TD in his last meeting with the Chargers. He had 1,220 yards from scrimmage last season and he is one of three NFL running backs with 1,200-plus scrimmage yards and seven-plus TDs in each of the past three seasons.

Most fantasy players don’t get excited about starting Jacobs and he may be in his last year with the Raiders, but he can find the end zone more than once in what should be a high-scoring matchup with the Chargers. Los Angeles' run defense should be improved but may take time to mesh this season. Jacobs should rush for at least a respectable amount of yards while also being a top drive-finishing option for an upgraded Las Vegas offense.

Rashaad Penny

Rashaad Penny had 135-plus rushing yards and a TD in four of his final five games in 2021. He is aiming to become just the fourth player in NFL history with 150-plus rushing yards and a TD in three consecutive games. Penny may not pull off that feat, but he will be a major central figure in the Seattle offensive game plan this week and he is a must-start as a flex player.

He is starting off the season in good health, and Penny should be brimming with confidence as he will get a lot of work again in the 2022 season opener.

Antonio Gibson

Antonio Gibson had a career-best 1,331 scrimmage yards and 10 TDs last season. He is one of five NFL running backs with 1,000-plus scrimmage yards and 10-plus scrimmage TDs in each of the past two seasons.

He has a chance to bounce back from a forgettable preseason in the 2022 opener, and Gibson can still post quality fantasy totals with a significant workload, which he appears to be in line for against Jacksonville in Week 1.

 

Wide Receivers - Fantasy Football Week 1

DeVonta Smith

DeVonta Smith ranked fourth among NFL rookies with an Eagles first-season record of 916 receiving yards last season. He also averaged 14.3 yards per catch. With A.J. Brown now operating as Philadelphia’s new No. 1 WR, Smith can be more comfortable as a second option.

The Eagles’ passing game will look instantly improved in their 2022 opener and Smith should be locked in as a fantasy WR3. He will get some opportunities to make downfield splash plays in Week 1.

JuJu Smith-Schueter

JuJu Smith-Schuster had 800-plus yards and seven-plus receiving TDs in three of his first five NFL seasons. In 2020, he had 97 receptions and nine TDs. Now he will work with the most explosive passer of his career so far.

Smith-Schuster should be the No. 1 WR target for Patrick Mahomes, who often makes some of his receivers perform above expectations. The highly vulnerable Arizona secondary is a very good draw for Smith-Schuster in his first game with the Chiefs.

Jarvis Landry

Jarvis Landry is one of three NFL wide receivers with 50-plus receptions in each of the past eight seasons. That stat reflects how dependable Landry has been over the years from pure NFL perspectives, as he will always have at least a decent floor in total receptions. Landry had a down season in 2021, but he can get back up in the 80-catch range with the Saints this season.

With Michael Thomas uncertain in regards to how productive he can be, and Chris Olavemaking his pro debut, Landry may be very busy as a target for Jameis Winston in his first game with New Orleans.

If you need an off-the-radar flex or WR streamer for the season opener, consider Landry, who may come through with more than six receptions this week against Atlanta.

Chase Claypool

Chase Claypool has 80-plus receiving yards in his last two meetings with the Bengals. Diontae Johnson is battling through a shoulder injury and George Pickens will be playing in his first NFL game.

There may be some thought about playing Claypool in Week 1 -- but with Mitchell Trubisky at QB against a solid Cincinnati secondary, it is better to fade Claypool.

 

Quarterbacks and Tight Ends - Fantasy Football Week 1

Tua Tagovailoa

Tua Tagovailoa had seven TD passes and two interceptions in his final five home games last season. Now he has improved weaponry and is under a bright spotlight, needing to show he can succeed with the right pieces around him.

Look for Tagovailoa to respond with a strong opener, and he will be a very good QB2 starter in superflex leagues in Week 1.

Derek Carr

Derek Carr had a career-high and Raiders franchise record 4,804 passing yards in 2021. He has two-plus TD passes in his last two games vs. Los Angeles and he has not been intercepted in six of his last seven matchups with the Chargers.

Carr is entering the 2022 season with his best receiving crew ever and the Chargers will be without top acquisition J.C. Jackson at CB. Carr will start the new campaign off with an impressive statistical outing.

Austin Hooper

Since 2016, Austin Hooper ranks fourth among all NFL TEs with 298 receptions. He should make an immediate impact with the Titans as a frequent target on key passing downs, and he is a viable replacement for Week 1 if you need to replace George Kittle.

Evan Engram

Evan Engram is one of three NFL TEs with 40-plus receptions over the past five seasons. The Jaguars have a mediocre WR crew and a TE-friendly offensive system. Engram is another good Kittle fill-in for Week 1.

Scott Engel's fantasy and betting analysis is also featured at The Game Day.



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REAL-TIME FANTASY NEWS

Michael Penix Jr.

Not Cleared for 11-on-11 Work
Jacoby Brissett

Still Absent From OTAs This Week
George Kittle

Still Hoping to be Ready for Week 1
Micah Parsons

Expected to Open Training Camp on the PUP List
Tucker Kraft

Packers Hopeful Tucker Kraft Will Participate in Training Camp
Jacory Croskey-Merritt

Held Out of OTAs on Wednesday
Jayden Daniels

Participating in Commanders OTAs
Chris Bell

No Timetable for Chris Bell's Return from Knee Surgery
De'Von Achane

Limited in OTAs Due to Recovery From Shoulder Injury
MarShawn Lloyd

Participating in Packers OTAs
Josh Jacobs

No Criminal Charges Filed Against Josh Jacobs
Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
Daniel Jones

Present at OTA Practice on Wednesday
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Drew Mestemaker a Top Big 12 Quarterback Right Away?
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Dynasty Stock Continues to Trend Down
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Is Jordan Addison a Clear Buy-Low Candidate Ahead of 2026?
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Continues to Offer Depth in Dynasty Leagues
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Sungjae Im Remains Boom-or-Bust at Colonial
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Continues to Have Dynasty Appeal at 31 Years Old
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No Clear Path to Fantasy Relevance for Tez Johnson in Tampa Bay?
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Michael Thorbjornsen Trending in Wrong Direction Entering Colonial
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Could Still Contribute in Dynasty Leagues
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Limited to Nine Points in Game 5 Loss
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a Top Option at Colonial
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Could Still Find Dynasty Relevance After Quiet Rookie Season
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Looks to Regain Momentum at Colonial
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Struggles in Game 5 Loss to Thunder
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Dynasty Value Has Run Dry in Crowded Running Back Room
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a Difference-Maker Again in Game 5
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Looking to Stay Hot at Colonial
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Scores Game-High 32 Points in Game 5 Win
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Faces Different Test at the Colonial
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Ups and Downs Could Continue at Colonial
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Struggling Too Often Heading to Charles Schwab Challenge
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Tries to Keep Momentum Rolling at Colonial
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Looking to Rebound at Colonial
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is Ruled Out for Game 5 on Tuesday
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Kenny Atkinson to Remain Cavaliers Head Coach Next Season
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Planning to Return for 20th NHL Campaign
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Aiming for Sixth Consecutive Win Tuesday
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Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
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Will Suit Up Tuesday
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Looking to Repeat This Week at Colonial
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a Player to Avoid at Charles Schwab Challenge
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Needs Solid Driving Week at Charles Schwab Challenge
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Braylon Staley the Next 1,000-Yard Tennessee Receiver?
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Scores Game 3 Winner in Overtime
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Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
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Dennis Schroder is Ruled Out for Game 4 on Monday
Michael Porter Jr.

Nets Could Trade Michael Porter Jr.
Valeri Nichushkin

Nathan MacKinnon, Valeri Nichushkin Uncertain for Game 4
Oliver Kapanen

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Heading to Injured List With Hamstring Injury
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Christopher Bell

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Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
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Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
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Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

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Kyle Larson

May have A Solid Day at Charlotte
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William Byron

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May not be Worth his Salary for Charlotte DFS Lineups
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Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

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Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

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Orioles-Tigers Game Postponed on Saturday
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Rays-Yankees Postponed on Saturday
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Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
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LSU Hires Ed Orgeron As Special Assistant
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North Carolina and South Carolina Cancel Home-And-Home Series
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Confidence High in Mississippi State's Kamario Taylor
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Reds-Cardinals Game Postponed on Friday
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Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
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