👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Props Tool
Compare Any Players
Compare Any Players
24x7 News and Alerts

College Football Betting Picks for Week Seven (10/16/2021)

Our college football CFB betting picks for Week Seven. Every week, Nick recommends the best CFB bets and top CFB wagers for the college football betting slate.

The chaos continues! After seeing Alabama, Penn State, BYU and Wyoming fall in Week Six, we are down to 13 remaining undefeated teams. The Alabama loss to unranked Texas A&M, in particular, is certain to shake up the postseason picture as the Crimson Tide now can't afford another loss and will need to likely defeat either Georgia or Kentucky in the SEC Championship.

Last week's picks ended with a 2-1 record. Kentucky's offense unexpectedly erupted, ruining any chance of hitting the under in their 42-21 demolishing of LSU. Meanwhile, in Provo, Utah, the BYU Cougars and Boise State Broncos battled in a 26-17 slugfest that cashed the over and knocked BYU from the ranks of the unbeaten. Lastly, Utah marched into Los Angeles and thwarted USC by 17 points, with the over never in doubt. The season-long record is 12-10.

For Week Seven of the college football season, here are some expert money-line and over/under betting picks.

Featured Promo: New Novig users get a $25 purchase match (50% discount up to $25) on your first Novig deposit, and 6 free months of RotoBaller's "Big-4" Premium Pass (NFL, NBA, MLB, NHL) which includes exclusive tools for Betting, Props, DFS and more! CLAIM IT NOW

 

Michigan State @ Indiana (+4.5)

O/U: 48.5

Coach Mel Tucker's 2021 Michigan State Spartans are not the typical team from East Lansing. Under Mike Dantonio's leadership, with the assistance of former defensive coordinator and current Pitt head coach Pat Narduzzi, the Spartans were known for their staunch defenses, control of the time of possession, and solid quarterback play. All three of those qualities are not the reasons for Michigan State's 6-0 start this year. Running back Kenneth Walker, a graduate transfer from Wake Forest, has amassed 913 rushing yards and 10 touchdowns, garnering some well-deserved Heisman consideration. Sophomore quarterback Payton Thorne joins Walker in the backfield, and he has played largely mistake-free football throwing 14 touchdowns to only two interceptions. The defense, however, gave up 560 total yards to Western Kentucky of Conference-USA, and has plenty of room for improvement.

Indiana has had a very difficult start to the 2021 campaign. Coach Tom Allen's team was stellar in 2020 - only losing a hard-fought game with Ohio State - but has yet to recapture the magic with a 2-3 start. Quarterback Michael Penix Jr., who was the catalyst for much of the Hoosiers' success a year ago, has struggled mightily throwing seven interceptions, while completing only four touchdown passes. Part of the issue is the lack of a running game, where Stephen Carr and Tim Baldwin combine to average 3.7 yards per carry (Stevie Scott averaged 6.6 yards per carry in 2020). Still, Penix has talented receivers in Ty Fryfogle, tight end Peyton Hendershot, Miles Marshall, and Florida State transfer DJ Matthews. If Penix can find a way to eliminate the interceptions issue, the Hoosiers can start showing the offensive firepower that made them a threat a season ago.

Uncommon for Big Ten football, neither defense jumps off the page in this game. In particular, Indiana's 90th ranked scoring defense is dismal. Expect the Spartans to lean heavily on Walker and Thorne to get on the board. Meanwhile, Penix has had the unpleasant task of facing vaunted defenses such as Iowa, Penn State, and Cincinnati in the early going, and will get a bit of a reprieve this week against a less talented Michigan State lineup.

Pick: Over 48.5

 

Want some more CFB DFS tools? If you like what you see here, don't forget to sign up for your RotoBaller CFB DFS Premium Pass. Use code BALLER and receive 10% off your purchase! You'll love the College Football DFS Lineup Optimizer, DFS Cheat Sheets Premium Slack Chatrooms to help you out in real-time.

 

Pittsburgh at Virginia Tech (+5)

O/U: 57.5

The Pitt Panthers, fresh off a bye-week, roll into Blacksburg, Virginia, with their eyes on the ACC Coastal division. Coach Pat Narduzzi's Panthers have been led by their fifth-year senior quarterback and two-time captain Kenny Pickett, who has accounted for 21 touchdowns and only one interceptions in the team's 4-1 start. The Panthers' running game has been a weakness, but in their 52-21 win at Georgia Tech, signs of life between freshman Rodney Hammond Jr. and sophomore Israel "Izzy" Abanikanda, emerged, with the Panthers amassing 181 yards on the ground. Leading the top-ranked scoring offense in the country (52.4 points per game), sophomore receiver Jordan Addison and super-senior tight end Lucas Krull give Pickett two big-time red zone threats, with nine and five touchdown receptions so far, respectively. The defense has not been as good as we are accustomed to, allowing 22.6 points per game, which is good for only 49th in the country, but this is partially by design as the Panthers like to blitz and bring pressure which leaves their young defensive backs on "islands."

If Virginia Tech coach Justin Fuente wasn't feeling the heat before the year, he certainly is now. The Hokies' 3-2 start isn't inspiring much confidence, with the team's defeat of North Carolina looking less-and-less impressive as the Tar Heels continue to lose. Last week's narrow loss to Notre Dame gutted the team after they blew a double digit fourth quarter lead. The Lane Stadium gameday experience is one that everyone should have on their bucket lists, and this week's 3:30pm start will give the Hokies some advantage, but less than last week's night game atmosphere. At quarterback, Braxton Burmeister has only completed 58.8% of his passes, but he really thrives as a runner. Burmeister was knocked out of the game last week, only to return, and is expected to play this week. If Burmeister is unable to go, little-used sophomore Knox Kadum would get the call (2nd string quarterback Connor Blumrick also was hurt last week). Burmeister does have two main threats he uses in the passing game - Tre Turner and Tayvion Robinson - who combine for 53% of the team's catches and 60% of the team's five touchdowns through the air. The offense leaves much to be desired, but the strength of this year's Hokies team lies on the defensive side, where an opponent has yet to eclipse 30 points all year.

In what should be one of the better games of the week, Pitt and Virginia Tech will battle to see who can become the frontrunner in the race for the ACC Coastal division. To date, Pitt has racked up incredible offensive statistics, but the list of opponents doesn't strike fear into many, aside from possibly the Tennessee win. Virginia Tech's defense is legit and could pose problems for Pickett and the Panthers. Pitt has been an impressive 5-0 in hitting overs this year, a number I expect to start falling due to regression and slightly more difficult opponents in the coming weeks.

Pick: Under 57.5

 

Marshall at North Texas (+11)

O/U: 66.5

The Marshall Thundering Herd are 3-3 under first-year head coach Charles Huff, who was most recently the running backs coach at Alabama. The Herd sport an offense with a solid ground threat from Rasheen Ali, who replaced Brenden Knox as Knox departed last year after a successful career in Huntington, West Virginia, for the NFL. The quarterback, sophomore Grant Wells, had a breakout 2020 campaign, but has been uneven in 2021. In six games, Wells has thrown only eight touchdowns against a staggering seven picks. In the passing game, Wells has found seven different receivers for double-digit receptions. The defense ranks 50th in points allowed per game, with disappointing losses to East Carolina and Middle Tennessee skewing the number.

The North Texas Mean Green are rebuilding in 2021 under Seth Littrell, who has led the program for six seasons. Quarterback play has been a big reason for the team's 1-4 start, with Jace Ruder and Austin Aune combining to throw eight touchdowns and seven interceptions. Young running back Deandre Torrey has flashed signs of excellence, and is averaging 5.2 yards per carry so far this year. An issue that the team has run into is the passing game relies so heavily on Roderic Burns, who has caught one of every three completions, that they can fall into dead spells for extended periods if he is neutralized. The defense has largely been poor, allowing 32.2 points per game, which is good for 107th in the nation.

Marshall should roll into Denton, Texas, and garner the victory, the only question might be what the final score is and could they cover the spread. The Mean Green have yet to display much on either side of the ball to excite people, and I expect another flat offensive performance from Coach Littrell's team.

Pick: Under 66.5



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis

POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Props Tool
Compare Any Players
Compare Any Players
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Thomas Bryant

Practices in Limited Capacity Wednesday
Spencer Jones

Limited at Wednesday's Practice
Peyton Watson

Limited to Non-Contact Work at Practice
Bam Adebayo

NBA Investigating LaMelo Ball's Trip of Bam Adebayo
Isaiah Jackson

Cleared for Wednesday
Terrance Ferguson

Can Terrance Ferguson Establish a More Consistent Role in 2026?
Dalton Schultz

Could See a Reduced Role in Houston in 2026
Kimani Vidal

Playing Time in Los Angeles an Open Question Heading into 2026
Juwan Johnson

Looking to Build on Breakout 2025 Campaign
Chuba Hubbard

Set to Re-Emerge as a Top-24 Running Back?
Gunnar Helm

Poised for Expanded Role in 2026
Immanuel Quickley

Remains Day-to-Day After Workout
Isaiah Jackson

Probable to Return for Play-In Game
Tyler Kolek

Returns to Practice Ahead of Playoffs
Trendon Watford

Active on Wednesday
Jonathan Isaac

Ruled Out for Play-In Game Wednesday
Dylan Harper

Expected to Suit Up for Game 1 on Sunday
Franz Wagner

to Remain on Minutes Restriction Wednesday
Shohei Ohtani

Will Pitch on Wednesday, But Won't DH
Nick Pivetta

Confident he'll Pitch Again This Year
Alex Lyon

Expected to Miss Playoff Opener
Jett Howard

Good to Go on Wednesday
Zach Hyman

Set to Return Thursday
Sam Steel

Back in Action Wednesday
Gustav Forsling

Sits Out Season Finale
OG Anunoby

Practices on Wednesday
Matthew Tkachuk

Rejoins Panthers Lineup Wednesday
TB

Max Crozier Available Against Rangers
Brandon Hagel

Returns for Regular-Season Finale
Trevor Story

Carries Red Sox With Five RBI on Wednesday
Sam Antonacci

Officially Called Up by White Sox
Jorge Soler

Suspension Reduced to Four Games
Harrison Bader

Giants Place Harrison Bader on 10-Day Injured List With Hamstring Strain
Matthew Golden

Packers "Clearing the Way" for Matthew Golden on WR Depth Chart
CFB

Michigan Lands Commitment From Quarterback Kamden Lopati
Arizona Cardinals

Ty Simpson Visiting With Cardinals on Wednesday
De'Von Achane

"Not Available for Trade"
Travis Hunter

Will Still Play Receiver in 2026
Ketel Marte

Serving as Designated Hitter on Wednesday
Kevin McGonigle

Tigers, Kevin McGonigle Agree to Eight-Year Contract Extension
Sahith Theegala

Brings Strong Form Into Harbour Town
Kansas City Chiefs

Jordyn Tyson in Play for Chiefs at No. 9 Overall in NFL Draft?
Wyndham Clark

Needs Putter to Show Up at RBC Heritage
Ryan Weathers

Allows Four Homers, Strikes Out 10 on Tuesday
Byron Buxton

Sets the Tone for Twins With Two Homers on Tuesday
Hunter Goodman

Homers Twice in Loss to Astros
JJ Wetherholt

Goes Yard Twice in Win Over Guardians
Colston Loveland

Could Colston Loveland Emerge as the Dynasty TE1?
Khalil Shakir

Has Khalil Shakir Fallen Too Far in Dynasty Rankings?
Christian Watson

How High is the Ceiling for Christian Watson?
Pat Freiermuth

Can Pat Freiermuth Become More Than a Depth Piece Again?
Cale Makar

Returns With Three-Assist Performance
Jimmy Snuggerud

Records First Career Four-Point Game
Tua Tagovailoa

How Much Value Does Tua Tagovailoa Offer as Falcons' Starter?
Jeremy Swayman

Ends Losing Run With Shutout Performance
Oliver Moore

Won't Play Wednesday
Nils Lundkvist

Returns for Regular-Season Finale
Roope Hintz

to Miss First Two Playoff Games
Pavel Zacha

Will Be Available for Start of Playoffs
Jalen Green

Scores Team-High 35 Points During Play-In Loss
Jrue Holiday

Nets 21 Points in Playoff Clincher
Deni Avdija

Helps Trail Blazers Into Playoffs With 41-Point Effort
Miles Bridges

Caps Off Big Night With Game-Winning Block
LaMelo Ball

Leads Hornets to Victory Versus Heat
Isaiah Jackson

Questionable Wednesday
Jacob Bridgeman

Looks to Return to Elite Form at Harbour Town
J.J. Spaun

a Volatile Option at RBC Heritage
PGA

Sungjae Im Offers High-Upside Value at RBC Heritage
Matt Fitzpatrick

Set for Another Strong Showing at RBC Heritage
Jason Day

Eyes Bounce-Back After Sunday Struggles at the Masters
Akshay Bhatia

Looking to Rebound at Harbour Town
Zay Flowers

Set to Face Competition After Career-Best Season?
Detroit Lions

Lions Open to Trading Up in the NFL Draft
New York Giants

Giants and Dexter Lawrence Reach a Contract Impasse
Jordan Mason

Is Jordan Mason's Buy-Low Window Still Open?
Dak Prescott

Still a Dynasty Target After Leading NFL in Completions
Ketel Marte

Diamondbacks Expect Ketel Marte to Return on Wednesday
Cameron Young

Hoping to Secure Second Win of Season at RBC Heritage
Scottie Scheffler

Looks to Win Again at RBC Heritage
Shane Lowry

Has Disappointing Final Round at Masters
Viktor Hovland

Hoping to Build on Final Round at Masters
Brian Harman

Struggling For Consistency Heading to RBC Heritage
Chris Gotterup

Putting Together Outstanding 2026 Season
Emilio Pagán

Emilio Pagan Getting Hamstring Checked After Earning Save on Tuesday
Justin Thomas

Looks to Defend in Hilton Head
Jordan Spieth

in Search of Improved Putting at RBC Heritage
Willson Contreras

Exits Early on Tuesday Due to Lower-Back Tightness
Marco Penge

May Continue Up-and-Down Ride at the RBC Heritage
Jerami Grant

Coming Off the Bench Tuesday
Xander Schauffele

Could Get The Job Done at RBC Heritage
Jake Knapp

Keeps Building Strong Results in 2026
Kurt Kitayama

Trying to Regain Form From Florida
Collin Morikawa

Continues to be a Scary DFS Play at RBC Heritage
Triston Casas

Shut Down With Abdominal Strain
Wyatt Langford

is Returning on Tuesday
Ketel Marte

Scratched on Tuesday With Back Tightness
Nick Pivetta

Heads to 15-Day Injured List With Elbow Inflammation
John Marino

a Game-Time Call Tuesday
Pyotr Kochetkov

Starting for Hurricanes Tuesday
Gabriel Moreno

Diamondbacks Put Gabriel Moreno on 10-Day Injured List With Oblique Strain
Matvei Gridin

Returns to Action Tuesday
Cole Ragans

Returning to the Mound on Tuesday Against Tigers
Ryan Pulock

Unavailable for Season Finale
Evander Kane

Not Expected to Play This Week
Erik Karlsson

Kris Letang Won't Play Tuesday
Sidney Crosby

Evgeni Malkin Resting on Tuesday
CFB

Tramell Jones Jr. Outperforms Aaron Philo During Florida's Spring Scrimmage
CFB

Keelon Russell Flashes in Alabama's Spring Game
Ty Gibbs

Holds off the Field for His First Cup Series Victory at Bristol
Ryan Blaney

Earns His First Runner-Up Finish at Bristol
Kyle Larson

Dominant Performance At Bristol Falls Short of Victory
Tyler Reddick

Matches his Career-Best Finish at Bristol
Alex Bowman

Crashes Early at Bristol in Return From Injury
Carlos Ulberg

Is The New Light Heavyweight Champion
Jiří Procházka

Jiri Prochazka Suffers First-Round Knockout Loss
Azamat Murzakanov

Suffers His First Loss
Paulo Costa

Wins Back-to-Back Fights
Curtis Blaydes

Drops Decision At UFC 327
Josh Hokit

Remains Unbeaten
Carson Hocevar

Is Carson Hocevar A Worthy DFS Option for Bristol Lineups?
NASCAR

Could Bubba Wallace Be A Solid DFS Option for Bristol Lineups?
Carlos Ulberg

A Slight Underdog
Jiří Procházka

Jiri Prochazka Can Become UFC Champion Again
Paulo Costa

Makes his Light-Heavyweight Debut
Azamat Murzakanov

Looks To Remain Unbeaten
Josh Hokit

Looks To Remain Undefeated
Curtis Blaydes

A Favorite At UFC 327
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF