👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


College Football Betting Picks for Week Seven (10/16/2021)

Our college football CFB betting picks for Week Seven. Every week, Nick recommends the best CFB bets and top CFB wagers for the college football betting slate.

The chaos continues! After seeing Alabama, Penn State, BYU and Wyoming fall in Week Six, we are down to 13 remaining undefeated teams. The Alabama loss to unranked Texas A&M, in particular, is certain to shake up the postseason picture as the Crimson Tide now can't afford another loss and will need to likely defeat either Georgia or Kentucky in the SEC Championship.

Last week's picks ended with a 2-1 record. Kentucky's offense unexpectedly erupted, ruining any chance of hitting the under in their 42-21 demolishing of LSU. Meanwhile, in Provo, Utah, the BYU Cougars and Boise State Broncos battled in a 26-17 slugfest that cashed the over and knocked BYU from the ranks of the unbeaten. Lastly, Utah marched into Los Angeles and thwarted USC by 17 points, with the over never in doubt. The season-long record is 12-10.

For Week Seven of the college football season, here are some expert money-line and over/under betting picks.

Featured Promo: New Novig users get a $25 purchase match (50% discount up to $25) on your first Novig deposit, and 6 free months of RotoBaller's "Big-4" Premium Pass (NFL, NBA, MLB, NHL) which includes exclusive tools for Betting, Props, DFS and more! CLAIM IT NOW

 

Michigan State @ Indiana (+4.5)

O/U: 48.5

Coach Mel Tucker's 2021 Michigan State Spartans are not the typical team from East Lansing. Under Mike Dantonio's leadership, with the assistance of former defensive coordinator and current Pitt head coach Pat Narduzzi, the Spartans were known for their staunch defenses, control of the time of possession, and solid quarterback play. All three of those qualities are not the reasons for Michigan State's 6-0 start this year. Running back Kenneth Walker, a graduate transfer from Wake Forest, has amassed 913 rushing yards and 10 touchdowns, garnering some well-deserved Heisman consideration. Sophomore quarterback Payton Thorne joins Walker in the backfield, and he has played largely mistake-free football throwing 14 touchdowns to only two interceptions. The defense, however, gave up 560 total yards to Western Kentucky of Conference-USA, and has plenty of room for improvement.

Indiana has had a very difficult start to the 2021 campaign. Coach Tom Allen's team was stellar in 2020 - only losing a hard-fought game with Ohio State - but has yet to recapture the magic with a 2-3 start. Quarterback Michael Penix Jr., who was the catalyst for much of the Hoosiers' success a year ago, has struggled mightily throwing seven interceptions, while completing only four touchdown passes. Part of the issue is the lack of a running game, where Stephen Carr and Tim Baldwin combine to average 3.7 yards per carry (Stevie Scott averaged 6.6 yards per carry in 2020). Still, Penix has talented receivers in Ty Fryfogle, tight end Peyton Hendershot, Miles Marshall, and Florida State transfer DJ Matthews. If Penix can find a way to eliminate the interceptions issue, the Hoosiers can start showing the offensive firepower that made them a threat a season ago.

Uncommon for Big Ten football, neither defense jumps off the page in this game. In particular, Indiana's 90th ranked scoring defense is dismal. Expect the Spartans to lean heavily on Walker and Thorne to get on the board. Meanwhile, Penix has had the unpleasant task of facing vaunted defenses such as Iowa, Penn State, and Cincinnati in the early going, and will get a bit of a reprieve this week against a less talented Michigan State lineup.

Pick: Over 48.5

 

Want some more CFB DFS tools? If you like what you see here, don't forget to sign up for your RotoBaller CFB DFS Premium Pass. Use code BALLER and receive 10% off your purchase! You'll love the College Football DFS Lineup Optimizer, DFS Cheat Sheets Premium Slack Chatrooms to help you out in real-time.

 

Pittsburgh at Virginia Tech (+5)

O/U: 57.5

The Pitt Panthers, fresh off a bye-week, roll into Blacksburg, Virginia, with their eyes on the ACC Coastal division. Coach Pat Narduzzi's Panthers have been led by their fifth-year senior quarterback and two-time captain Kenny Pickett, who has accounted for 21 touchdowns and only one interceptions in the team's 4-1 start. The Panthers' running game has been a weakness, but in their 52-21 win at Georgia Tech, signs of life between freshman Rodney Hammond Jr. and sophomore Israel "Izzy" Abanikanda, emerged, with the Panthers amassing 181 yards on the ground. Leading the top-ranked scoring offense in the country (52.4 points per game), sophomore receiver Jordan Addison and super-senior tight end Lucas Krull give Pickett two big-time red zone threats, with nine and five touchdown receptions so far, respectively. The defense has not been as good as we are accustomed to, allowing 22.6 points per game, which is good for only 49th in the country, but this is partially by design as the Panthers like to blitz and bring pressure which leaves their young defensive backs on "islands."

If Virginia Tech coach Justin Fuente wasn't feeling the heat before the year, he certainly is now. The Hokies' 3-2 start isn't inspiring much confidence, with the team's defeat of North Carolina looking less-and-less impressive as the Tar Heels continue to lose. Last week's narrow loss to Notre Dame gutted the team after they blew a double digit fourth quarter lead. The Lane Stadium gameday experience is one that everyone should have on their bucket lists, and this week's 3:30pm start will give the Hokies some advantage, but less than last week's night game atmosphere. At quarterback, Braxton Burmeister has only completed 58.8% of his passes, but he really thrives as a runner. Burmeister was knocked out of the game last week, only to return, and is expected to play this week. If Burmeister is unable to go, little-used sophomore Knox Kadum would get the call (2nd string quarterback Connor Blumrick also was hurt last week). Burmeister does have two main threats he uses in the passing game - Tre Turner and Tayvion Robinson - who combine for 53% of the team's catches and 60% of the team's five touchdowns through the air. The offense leaves much to be desired, but the strength of this year's Hokies team lies on the defensive side, where an opponent has yet to eclipse 30 points all year.

In what should be one of the better games of the week, Pitt and Virginia Tech will battle to see who can become the frontrunner in the race for the ACC Coastal division. To date, Pitt has racked up incredible offensive statistics, but the list of opponents doesn't strike fear into many, aside from possibly the Tennessee win. Virginia Tech's defense is legit and could pose problems for Pickett and the Panthers. Pitt has been an impressive 5-0 in hitting overs this year, a number I expect to start falling due to regression and slightly more difficult opponents in the coming weeks.

Pick: Under 57.5

 

Marshall at North Texas (+11)

O/U: 66.5

The Marshall Thundering Herd are 3-3 under first-year head coach Charles Huff, who was most recently the running backs coach at Alabama. The Herd sport an offense with a solid ground threat from Rasheen Ali, who replaced Brenden Knox as Knox departed last year after a successful career in Huntington, West Virginia, for the NFL. The quarterback, sophomore Grant Wells, had a breakout 2020 campaign, but has been uneven in 2021. In six games, Wells has thrown only eight touchdowns against a staggering seven picks. In the passing game, Wells has found seven different receivers for double-digit receptions. The defense ranks 50th in points allowed per game, with disappointing losses to East Carolina and Middle Tennessee skewing the number.

The North Texas Mean Green are rebuilding in 2021 under Seth Littrell, who has led the program for six seasons. Quarterback play has been a big reason for the team's 1-4 start, with Jace Ruder and Austin Aune combining to throw eight touchdowns and seven interceptions. Young running back Deandre Torrey has flashed signs of excellence, and is averaging 5.2 yards per carry so far this year. An issue that the team has run into is the passing game relies so heavily on Roderic Burns, who has caught one of every three completions, that they can fall into dead spells for extended periods if he is neutralized. The defense has largely been poor, allowing 32.2 points per game, which is good for 107th in the nation.

Marshall should roll into Denton, Texas, and garner the victory, the only question might be what the final score is and could they cover the spread. The Mean Green have yet to display much on either side of the ball to excite people, and I expect another flat offensive performance from Coach Littrell's team.

Pick: Under 66.5



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis

REAL-TIME FANTASY NEWS

Josh Sweat

Cardinals Won't Trade Josh Sweat
Mac Jones

Not Throwing Due to "Soreness"
Aaron Judge

to Undergo Additional Imaging
Adonai Mitchell

Chemistry With New Jets QB is Growing
Darnell Washington

Steelers, Darnell Washington Agree to Four-Year Extension
Micah Parsons

Eyeing a Mid-October Return After Having Another Knee Surgery
Rome Odunze

Foot Injury Still an Issue Going into 2026 Season?
Ketel Marte

Out on Wednesday With Back, Hamstring Injuries
Mitchell Robinson

is Available for Game 1 on Wednesday
Kawhi Leonard

Unlikely to be Traded
Chicago Bulls

Bulls Host Potential Lottery Picks for Workout
Washington Wizards

Wizards Considering Trading Down in Draft
Russell Wilson

Retiring From the NFL
Corbin Burnes

has Teres Major Strain, Unlikely to Return Until September
Malik Davis

Appears to be the Front-Runner for RB2 Job in Dallas
Kayshon Boutte

to Compete for Snaps in Three-Receiver Sets
Alvin Kamara

Attends OTAs on Wednesday
Andrei Iosivas

Is it Time for Dynasty Managers to Drop Andrei Iosivas?
Tyjae Spears

Is Tyjae Spears Droppable in Dynasty Formats?
Jaylen Wright

the Dynasty Handcuff Running Back to Own in Miami?
Colby Parkinson

Facing Likely Regression After Career Year in 2025
Omarion Hampton

Remains a High-End Dynasty RB1 Despite Injury History
Rickie Fowler

Looks To Continue Resurgent Season At Memorial
Ollie Gordon II

Is Ollie Gordon II Still Worthy of a Dynasty Roster Spot?
Justin Herbert

Overhauling his Footwork This Offseason
De'Von Achane

Doing Individual Drills at Minicamp
Ashton Jeanty

Raiders Emphasizing Ashton Jeanty's Progress as Their Lead Back
Marvin Harrison Jr.

Still on the Mend From 2025 Injuries
Brandon Aiyuk

Warrant Issued for Brandon Aiyuk's Arrest in California
CFB

Can Eric Singleton Jr. Fully Break Out at Third School?
CFB

Katin Houser Steps into QB1 Role for Illinois
CFB

Savion Hiter an Immediate Impact Freshman for Michigan
CFB

Isaiah Horton Set to Take Over KC Concepcion's Role
CFB

UCLA Transfer Karson Gordon Signs with Austin Peay
CFB

Will Muschamp Bringing New Intensity to Texas Practices
Gary Woodland

Brings Boom-or-Bust Potential to Memorial
Jordan Spieth

Still Searching for a Breakthrough
Alex Smalley

Brings Elite Form to Memorial Tournament
Justin Rose

Looks to Recapture Memorial Tournament Success
Cameron Young

Looks to Get Back to His Contending Ways at Murifield Village
Chris Gotterup

Needs to Find Fairways at Muirfield Village
Si Woo Kim

Looks to Stay Hot at Memorial Tournament
Matt Fitzpatrick

Positioned for Success at Muirfield Village
Jalen Chatfield

Records Two Assists in Tuesday's Loss
Keegan Bradley

Looking for Another Strong Finish at Muirfield
Nikolaj Ehlers

Nets Two Goals in Game 1 Loss to Golden Knights
Shea Theodore

Notches Three Points in Game 1 Win
Brayden McNabb

Sets Up Three Goals in Game 1 Win Over Hurricanes
Justin Thomas

is an Exciting Play This Week in Ohio
Brett Howden

Starts Finals With Multi-Point Effort
Scottie Scheffler

Looks to Win Memorial Tournament for Third Consecutive Year
Tomas Hertl

Scores Game-Winner in Finals Opener
Rory McIlroy

Looking for Better Performance at Muirfield Village
Drake Baldwin

Could Return During Braves Next Homestand
Garrett Crochet

Diagnosed With Low-Grade Lat Strain
Russell Henley

Coming to Ohio on the Heels of Latest Victory
Tommy Fleetwood

Looking for Better Iron Play at Memorial Tournament
Patrick Cantlay

Looks to Continue Dominance at Muirfield Village
Ludvig Aberg

a Great Fit for Muirfield Village
Isaiah Hartenstein

Hopeful to Stay with Oklahoma City
Luguentz Dort

Wants to Remain with Thunder
Mitchell Robinson

is Questionable for Game 1
Moussa Diabaté

Moussa Diabate Has Contract Guaranteed for 2026-2027 Season
Oso Ighodaro

Gets Guaranteed Contract for Next Season
NAS

Chris MacFarland Joins Predators as President and General Manager
VAN

Canucks Name Manny Malhotra as New Head Coach
Brendan Gallagher

to Leave Canadiens This Offseason
Patrik Laine

Looking Forward to Free Agency
Jeremy Lauzon

Returns to Action Tuesday
Zach Werenski

Wins 2025-26 Norris Trophy
Aaron Judge

Out on Tuesday With Rib/Shoulder Injury
Josh Hader

Set to Return from Injured List on Tuesday
CFB

SEC Coach Calls Buster Faulkner a "Home-Run Hire"
CFB

Auburn a Sleeper in the SEC Under Alex Golesh?
CFB

Noah Fifita Primed for Strong 2026 Campaign
CFB

Oregon Assistant Coach Charged with DUII, Reckless Driving
CFB

Tight End Nick Pollack Commits to Clemson
Akshay Bhatia

Needs the Driver to be True in Ohio
Aaron Rai

Primed to take on the Memorial Tournament
J.J. Spaun

Rebounded at Charles Schwab Challenge
Xander Schauffele

One to Watch This Week in Ohio
Elly De La Cruz

to Miss 2-4 Weeks of Action
Chase Burns

is Scratched Due to Illness
Deiveson Figueiredo

Suffers Second-Round Submission Loss
Song Yadong

Gets Second-Round Submission Win
Zhang Mingyang

Suffers Back-To-Back Losses
Alonzo Menifield

Gets Back In The Win Column
Tallison Teixeira

Suffers First-Round Knockout Loss
Sergei Pavlovich

Scores First-Round Knockout Win
Cameron Smotherman

Suffers Third Loss In A Row
Edwin Arroyo

Reds Promote Top Infield Prospect Edwin Arroyo, Viewed as Priority Pick Up Ahead of MLB Debut
Kai Asakura

Earns His First UFC Win
Elly De La Cruz

Placed on IL with Right Hamstring Tightness
Denny Hamlin

Earns the first Nashville Cup Series Victory of his Career on Sunday
Christopher Bell

Finishes as the Runner-Up at Nashville
Chase Briscoe

Earns First Career Podium Finish at Nashville
Ryan Blaney

Scores A Solid Top-10 Finish at Nashville
Kyle Larson

Top-10 Streak at Nashville Ends after Late Flat Tire Spin
Elly De La Cruz

Exits with Hamstring Tightness
Tyler Reddick

Is One of the Top Favorites to Win at Nashville
Kyle Larson

May Continue his Top-10 Consistency at Nashville this week
Christopher Bell

Is One of the Top Competitors for the Win at Nashville
Chase Briscoe

Is A Must Start for Nashville DFS Lineups
Chase Elliott

has Plenty of Upside for Nashville DFS Lineups
William Byron

Is William Byron A Playable DFS Option for Nashville Lineups?
Carson Hocevar

Is Likely to have Another Solid Result at Nashville
NASCAR

Should Fantasy Players Roster Bubba Wallace at Nashville?
Chris Buescher

Is A Decent All-Around DFS Option for Nashville Lineups
Daniel Suarez

is Likely to Drop Positions during the Cracker Barrel 400
Garrett Crochet

Suffers Setback, Likely to Undergo MRI for Lat Tightness
Denny Hamlin

Could Denny Hamlin Dominate at Nashville?
Ryan Blaney

Is a DFS Tournament Option at Nashville
Ty Gibbs

Don't Overlook Ty Gibbs at Nashville
Joey Logano

Could Show Life at Nashville
Ross Chastain

Needs a Good Run at Nashville
Chet Holmgren

Fails to Step Up in the Season Finale
Cason Wallace

Ends Postseason with Strong Showing
Shai Gilgeous-Alexander

Caps MVP Season with Game 7 Exit
Stephon Castle

Continues Postseason Run with 16 Points
Julian Champagnie

Shines in Series-Clinching Win
De'Aaron Fox

Provides Secondary Punch in Game 7 Triumph
Victor Wembanyama

Earns Conference Finals MVP in Spurs' Game 7 Win
NBA

Warriors Prioritize Depth Around Returning Steve Kerr
Donovan Mitchell

Remains Cleveland's Top Priority
Adou Thiero

Remains a Lakers Development Project
NBA

76ers Hire Mike Gansey as President of Basketball Operations
NBA

Chicago Bulls Explore Kevin Young as Coaching Candidate
Lane Hutson

Posts a Power-Play Assist in Game 5 Loss
Cole Caufield

Nets a Power-Play Goal in Season-Ending Loss
Seth Jarvis

Closes Out East Finals With Multi-Point Game
Logan Stankoven

Notches Three Points in Big Game 5 Win
Taylor Hall

Racks Up Three Points in Series-Clinching Win
Frederik Andersen

Remains Stellar as Hurricanes Clinch Finals Berth
Jacob Gonzalez

is Heading to the Big Leagues
Munetaka Murakami

Exits with Hamstring Tightness
Eury Pérez

Eury Perez is Placed on 15-Day Injured List
Deiveson Figueiredo

Set For UFC Macau Main Event
MMA

Yadong Song Returns At UFC Macau
Alonzo Menifield

An Underdog At UFC Macau
Zhang Mingyang

Set For UFC Macau Co-Main Event
Tallison Teixeira

Looks To Win Back-To-Back Fights
Sergei Pavlovich

A Favorite At UFC Macau
Cameron Smotherman

Looks To Bounce Back
Kai Asakura

Looks To Get Back In The Win Column
CFB

Faizon Brandon In Position to Start Week 1
CFB

Dane Weber Commits to Cal
CFB

Joey McGuire Attempts to Add Texas to Schedule
CFB

Mike Leach on 2027 College Football Hall of Fame Ballot
CFB

Maryland, Baylor Schedule Home-and-Home
CFB

Taron Dickens Decommits From North Carolina
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF