👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

College Football Betting Picks for Week Seven (10/16/2021)

Our college football CFB betting picks for Week Seven. Every week, Nick recommends the best CFB bets and top CFB wagers for the college football betting slate.

The chaos continues! After seeing Alabama, Penn State, BYU and Wyoming fall in Week Six, we are down to 13 remaining undefeated teams. The Alabama loss to unranked Texas A&M, in particular, is certain to shake up the postseason picture as the Crimson Tide now can't afford another loss and will need to likely defeat either Georgia or Kentucky in the SEC Championship.

Last week's picks ended with a 2-1 record. Kentucky's offense unexpectedly erupted, ruining any chance of hitting the under in their 42-21 demolishing of LSU. Meanwhile, in Provo, Utah, the BYU Cougars and Boise State Broncos battled in a 26-17 slugfest that cashed the over and knocked BYU from the ranks of the unbeaten. Lastly, Utah marched into Los Angeles and thwarted USC by 17 points, with the over never in doubt. The season-long record is 12-10.

For Week Seven of the college football season, here are some expert money-line and over/under betting picks.

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

 

Michigan State @ Indiana (+4.5)

O/U: 48.5

Coach Mel Tucker's 2021 Michigan State Spartans are not the typical team from East Lansing. Under Mike Dantonio's leadership, with the assistance of former defensive coordinator and current Pitt head coach Pat Narduzzi, the Spartans were known for their staunch defenses, control of the time of possession, and solid quarterback play. All three of those qualities are not the reasons for Michigan State's 6-0 start this year. Running back Kenneth Walker, a graduate transfer from Wake Forest, has amassed 913 rushing yards and 10 touchdowns, garnering some well-deserved Heisman consideration. Sophomore quarterback Payton Thorne joins Walker in the backfield, and he has played largely mistake-free football throwing 14 touchdowns to only two interceptions. The defense, however, gave up 560 total yards to Western Kentucky of Conference-USA, and has plenty of room for improvement.

Indiana has had a very difficult start to the 2021 campaign. Coach Tom Allen's team was stellar in 2020 - only losing a hard-fought game with Ohio State - but has yet to recapture the magic with a 2-3 start. Quarterback Michael Penix Jr., who was the catalyst for much of the Hoosiers' success a year ago, has struggled mightily throwing seven interceptions, while completing only four touchdown passes. Part of the issue is the lack of a running game, where Stephen Carr and Tim Baldwin combine to average 3.7 yards per carry (Stevie Scott averaged 6.6 yards per carry in 2020). Still, Penix has talented receivers in Ty Fryfogle, tight end Peyton Hendershot, Miles Marshall, and Florida State transfer DJ Matthews. If Penix can find a way to eliminate the interceptions issue, the Hoosiers can start showing the offensive firepower that made them a threat a season ago.

Uncommon for Big Ten football, neither defense jumps off the page in this game. In particular, Indiana's 90th ranked scoring defense is dismal. Expect the Spartans to lean heavily on Walker and Thorne to get on the board. Meanwhile, Penix has had the unpleasant task of facing vaunted defenses such as Iowa, Penn State, and Cincinnati in the early going, and will get a bit of a reprieve this week against a less talented Michigan State lineup.

Pick: Over 48.5

 

Want some more CFB DFS tools? If you like what you see here, don't forget to sign up for your RotoBaller CFB DFS Premium Pass. Use code BALLER and receive 10% off your purchase! You'll love the College Football DFS Lineup Optimizer, DFS Cheat Sheets Premium Slack Chatrooms to help you out in real-time.

 

Pittsburgh at Virginia Tech (+5)

O/U: 57.5

The Pitt Panthers, fresh off a bye-week, roll into Blacksburg, Virginia, with their eyes on the ACC Coastal division. Coach Pat Narduzzi's Panthers have been led by their fifth-year senior quarterback and two-time captain Kenny Pickett, who has accounted for 21 touchdowns and only one interceptions in the team's 4-1 start. The Panthers' running game has been a weakness, but in their 52-21 win at Georgia Tech, signs of life between freshman Rodney Hammond Jr. and sophomore Israel "Izzy" Abanikanda, emerged, with the Panthers amassing 181 yards on the ground. Leading the top-ranked scoring offense in the country (52.4 points per game), sophomore receiver Jordan Addison and super-senior tight end Lucas Krull give Pickett two big-time red zone threats, with nine and five touchdown receptions so far, respectively. The defense has not been as good as we are accustomed to, allowing 22.6 points per game, which is good for only 49th in the country, but this is partially by design as the Panthers like to blitz and bring pressure which leaves their young defensive backs on "islands."

If Virginia Tech coach Justin Fuente wasn't feeling the heat before the year, he certainly is now. The Hokies' 3-2 start isn't inspiring much confidence, with the team's defeat of North Carolina looking less-and-less impressive as the Tar Heels continue to lose. Last week's narrow loss to Notre Dame gutted the team after they blew a double digit fourth quarter lead. The Lane Stadium gameday experience is one that everyone should have on their bucket lists, and this week's 3:30pm start will give the Hokies some advantage, but less than last week's night game atmosphere. At quarterback, Braxton Burmeister has only completed 58.8% of his passes, but he really thrives as a runner. Burmeister was knocked out of the game last week, only to return, and is expected to play this week. If Burmeister is unable to go, little-used sophomore Knox Kadum would get the call (2nd string quarterback Connor Blumrick also was hurt last week). Burmeister does have two main threats he uses in the passing game - Tre Turner and Tayvion Robinson - who combine for 53% of the team's catches and 60% of the team's five touchdowns through the air. The offense leaves much to be desired, but the strength of this year's Hokies team lies on the defensive side, where an opponent has yet to eclipse 30 points all year.

In what should be one of the better games of the week, Pitt and Virginia Tech will battle to see who can become the frontrunner in the race for the ACC Coastal division. To date, Pitt has racked up incredible offensive statistics, but the list of opponents doesn't strike fear into many, aside from possibly the Tennessee win. Virginia Tech's defense is legit and could pose problems for Pickett and the Panthers. Pitt has been an impressive 5-0 in hitting overs this year, a number I expect to start falling due to regression and slightly more difficult opponents in the coming weeks.

Pick: Under 57.5

 

Marshall at North Texas (+11)

O/U: 66.5

The Marshall Thundering Herd are 3-3 under first-year head coach Charles Huff, who was most recently the running backs coach at Alabama. The Herd sport an offense with a solid ground threat from Rasheen Ali, who replaced Brenden Knox as Knox departed last year after a successful career in Huntington, West Virginia, for the NFL. The quarterback, sophomore Grant Wells, had a breakout 2020 campaign, but has been uneven in 2021. In six games, Wells has thrown only eight touchdowns against a staggering seven picks. In the passing game, Wells has found seven different receivers for double-digit receptions. The defense ranks 50th in points allowed per game, with disappointing losses to East Carolina and Middle Tennessee skewing the number.

The North Texas Mean Green are rebuilding in 2021 under Seth Littrell, who has led the program for six seasons. Quarterback play has been a big reason for the team's 1-4 start, with Jace Ruder and Austin Aune combining to throw eight touchdowns and seven interceptions. Young running back Deandre Torrey has flashed signs of excellence, and is averaging 5.2 yards per carry so far this year. An issue that the team has run into is the passing game relies so heavily on Roderic Burns, who has caught one of every three completions, that they can fall into dead spells for extended periods if he is neutralized. The defense has largely been poor, allowing 32.2 points per game, which is good for 107th in the nation.

Marshall should roll into Denton, Texas, and garner the victory, the only question might be what the final score is and could they cover the spread. The Mean Green have yet to display much on either side of the ball to excite people, and I expect another flat offensive performance from Coach Littrell's team.

Pick: Under 66.5



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis

POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Tyrone Tracy Jr.

Part of a Muddled Giants Backfield Heading into 2026
Chimere Dike

Fantasy Value Potentially Limited by What He Offers in Return Game
Chase Brown

an Important Name to Monitor on Day 1 of the NFL Draft
Bijan Robinson

Could Just Be Entering His Prime
Jameson Williams

Consistency the Key to a True Jameson Williams Breakout
Jarace Walker

May Exit Pacers Lineup Again Thursday
Aaron Nesmith

Out for Sixth Consecutive Game
T.J. McConnell

Andrew Nembhard, T.J. McConnell Unavailable Thursday
Dru Smith

Iffy for Thursday
Norman Powell

Questionable Thursday
Sam Hauser

Could Miss Thursday's Game
Neemias Queta

Uncertain for Thursday
Zach Benson

Scores Twice in Comeback Victory
Logan Thompson

Shuts Out the Leafs
Zach Eflin

Undergoes Successful Elbow Surgery, Will Miss Remainder of 2026
Derrick White

Listed as Questionable for Thursday
Tre Johnson

Iffy for Thursday
Jaylen Brown

Iffy to Face Knicks
Bilal Coulibaly

Questionable Against Bulls
Gui Santos

Could Miss Another Game Thursday
Alexandre Sarr

Out Again Thursday
Al Horford

to Remain Out Thursday
Caleb Martin

Remains Sidelined Wednesday
Kristaps Porzingis

Unavailable Against Lakers
Klay Thompson

Ruled Out Wednesday
Stephen Curry

Questionable for Thursday Night
Brandon Williams

to Miss Back-To-Back with Illness
LeBron James

Ready to Return Thursday
Daniel Gafford

Ruled Out Vs. Phoenix
J.K. Dobbins

Broncos Prioritized Re-Signing J.K. Dobbins
NFL

Francis Mauigoa to Undergo Additional Imaging on a Back Issue
Kaleb McGary

Retires After Seven Years in the NFL
Jawaan Taylor

Signs with the Falcons
Andrei Kuzmenko

to Be Re-Evaluated in 7-8 Days
Mason Appleton

Won't Play Thursday
Tony DeAngelo

Expected to Return Thursday
John Klingberg

Rejoins Sharks Lineup Wednesday
Alex Lyon

Dealing With Lower-Body Injury
Oliver Ekman-Larsson

Back in Action Wednesday
Alex Ovechkin

Won't Decide Future Until Offseason
Cole Ragans

"Should be Good" for Next Start
Reynaldo López

Reynaldo Lopez Handed Seven-Game Suspension
Jorge Soler

Suspended Seven Games, Will Appeal
NFL

NFL Scouts See Plenty of Upside With Drew Allar
NFL

Ty Simpson to Fall into Second Round in NFL Draft?
Cleveland Browns

Todd Monken "Fired Up" About Quarterback Competition
Cleveland Browns

KC Concepcion Visiting With the Browns
Cole Ragans

Diagnosed With Thumb Contusion
Houston Texans

Texans Pick Up Will Anderson's Fifth-Year Option
C.J. Stroud

Texans Exercise C.J. Stroud's Fifth-Year Option
Cole Ragans

Leaves Early on Wednesday After Being Hit in the Hand
Jacob deGrom

Expects to Make his Next Start
Konnor Griffin

Pirates Sign Konnor Griffin to Nine-Year Extension
Parker Washington

Undervalued Despite League-Winning Finish in 2025
Nico Collins

Is Nico Collins Still a Dynasty WR1?
Rome Odunze

Does Rome Odunze Offer the Highest Ceiling in Chicago?
Justus Annunen

Ends Predators' 120-Game Streak Without a Shutout
Tank Bigsby

Still Holds Value Despite Limited Usage
Trevor Zegras

Leads Flyers to Victory Tuesday
Matthew Golden

A Matthew Golden Breakout Still Faces Obstacles
Kevin Bahl

Sustains Lower-Body Injury Against Stars
Michael Rasmussen

Likely to Miss Rest of Regular Season
Dmitry Kulikov

Done for the Season After Breaking Finger
Jalen Chatfield

Exits Early With Lower-Body Injury
Nazem Kadri

Suffers Upper-Body Injury Tuesday
Ray Davis

Patience Dwindling for Ray Davis' Dynasty Managers?
Tyrrell Hatton

a Steady Option at The Masters
Justin Thomas

a High-Risk, High-Reward Option at The Masters
PGA

Sungjae Im a Volatile Option at the Masters
Nicolai Hojgaard

Carrying Momentum Into The Masters
Si Woo Kim

in Strong Form Heading to The Masters
Chris Gotterup

Ready to Make His Masters Debut
Patrick Reed

Brings Momentum to The Masters
Jon Rahm

Looks Poised for His Second Green Jacket
Morgan Geekie

Collects Second Career Hat Trick
Joel Eriksson Ek

has Three Points in Victory
Jacob deGrom

Doesn't Have Structural Damage in his Knee
J.T. Realmuto

Leaves Game on Tuesday Due to Bruised Right Foot
Cody Ponce

to Have Knee Surgery, Expected to Miss Six Months
Alejandro Kirk

Facing Six-Week Absence
Jacob deGrom

to Undergo MRI on Tuesday
Mike Trout

Back in the Lineup on Tuesday
Hunter Brown

Diagnosed with Grade 2 Shoulder Strain
Pavel Mintyukov

Returns From Three-Game Absence
Cutter Gauthier

Remains Sidelined Tuesday
Kirby Dach

Ready to Return Tuesday
Adam Scott

Form Points to Him Competing at Masters
Jordan Spieth

Finding Consistency Heading to Masters
Hideki Matsuyama

Trending In Right Direction For Masters
Cade Horton

to Undergo Season-Ending Elbow Surgery
Tommy Fleetwood

a Contender if his Putter Cooperates at The Masters
Jacob deGrom

Pitches Through Knee Issue on Monday
Dalton Rushing

Smacks Two Homers in Rout of Blue Jays
Max Scherzer

Dealing With Forearm Tendinitis, Expected to Make his Next Start
Collin Morikawa

Vegas has Lost Confidence in Collin Morikawa Ahead of Masters Tournament
Ludvig Aberg

One of the Top Plays For This Week's Masters Tournament
Rory McIlroy

Set to Defend his Long-Awaited Masters Victory
Bryson DeChambeau

Looks to Finally Claim a Green Jacket
Patrick Cantlay

Needs Plenty to Go Right at Augusta
Harris English

Playing Solid Golf Heading to Masters
Sam Burns

Bouncing Back Nicely After Slow Start to 2026 Season
Corey Conners

Quietly Putting Together A Strong 2026 Season
Russell Henley

Looks to Bounce Back At Masters
Mike Trout

Held Out of Series Opener Against Braves
Alejandro Kirk

to Undergo Thumb Surgery on Tuesday
Chris Duncan

Suffers Second-Round Submission Loss
Renato Moicano

Gets Back In The Win Column
Tabatha Ricci

Gets Outgrappled
Virna Jandiroba

Bounces Back
Brendson Ribeiro

Suffers First-Round Submission Loss
Abdul-Rakhman Yakhyaev

Earns First-Round Submission Win
Rafael Estevam

Suffers His First Loss
Ethyn Ewing

Dominates At UFC Vegas 115
Chris Duncan

Set For UFC Vegas 115 Main Event
Renato Moicano

An Underdog At UFC Vegas 115
Tabatha Ricci

Set For UFC Vegas 115 Co-Main Event
Virna Jandiroba

Looks To Bounce Back
Brendson Ribeiro

In Desperate Need Of Win
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF