TAP FOR 6 MONTHS OF PREMIUM FREE 💰
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

49ers vs. Seahawks TNF Start 'Em, Sit 'Em: Brock Purdy, Jordan Mason, Deebo Samuel, George Kittle, Geno Smith, Kenneth Walker III, DK Metcalf, more

Fantasy football start 'em, sit 'em, and lineup advice for the 49ers and Seahawks on Thursday Night Football in Week 6 (2024). Detailed player breakdowns and TNF matchup analysis.

Thursday Night Football for Week 6 presents two bitter rivals from an NFC West division that has been turned on its head since the start of the 2024 NFL season. Many of the fantasy football options from this division (Christian McCaffrey, Cooper Kupp, Puka Nacua, and Trey McBride) have been hurt or have underperformed. In addition, not all teams are performing to preseason expectations.

Consider that the two teams projected to make the playoffs -- the 49ers and the Rams -- are in third and fourth place, respectively, and are a combined 3-7. Seattle and Arizona have exceeded expectations, but the division is upside down. These four teams are a combined 2-6 in their last eight games somehow. As the division matchups kick into high gear this week, will one team emerge as a favorite?

I will bring you Thursday Night Football analysis all year, focusing on who to start, who is on the fence, and who should find the bench. Let's dive into this next awesome Thursday night matchup for Week 6 of the 2024 season. Good luck, RotoBallers!

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

 

San Francisco 49ers at Seattle Seahawks - 8:20 p.m. EDT

Notable Injuries:

 

49ers at Seahawks Matchup Breakdown

This matchup between the 49ers and Seahawks comes down to a tale of two teams in the red zone. If you just look at offensive touchdowns, you would think these teams are about equal on offense. Seattle scores 2.8 touchdowns per game compared to 2.2 for San Francisco.

But only one of these teams has been efficient near the end zone this season, and it's not the team that many were picking to win the Super Bowl. Seattle is scoring 2.8 touchdowns per game on 2.2 red-zone trips per game (30th in the NFL). San Francisco is scoring 2.2 touchdowns on 4.4 red-zone trips per game (third in the NFL).

The 49ers have scored touchdowns on just 40.9% of their red-zone trips this year, which is 29th in football. That has to change if they want to compete for the playoffs. Fortunately, this matchup against the Seattle defense might be the get-right spot.

Seattle lost 29-20 at home to the New York Giants last week, and it would have looked a lot worse if not for a goal-line fumble (that was returned for a touchdown) by New York. The game was a half-yard from being a 36-13 shellacking.

Seattle is 29th in football, allowing 3.8 red-zone scoring attempts per game. San Francisco has to convert in that area when it pushes Seattle that far.

 

Must-Starts for Fantasy Football Lineups

Brock Purdy (QB, SF)

After a 10-point dud in Week 1, Brock Purdy has at least 15 fantasy points in four straight games. He has all his pass-catchers healthy, and can still pick up points with his legs as well. Daniel Jones just dropped 22 points on Seattle with a backup running back and no Malik Nabers.

Jordan Mason (RB, SF)

What more needs to be said about Jordan Mason in Christian McCaffrey's absence? He is second in the NFL in rushing yards, first in attempts, and third in rushing yards per game. Despite never having anything like this kind of workload, Mason is averaging more than five yards per rush.

Deebo Samuel Sr. (WR, SF)

If last week was Brandon Aiyuk week, look for Deebo Samuel to bounce back in Week 6. After just one catch for 11 yards, Samuel remains a must-start because of his versatility, yards after the catch ability, and the fact that he is essentially the backup running back to Jordan Mason right now.

Brandon Aiyuk (WR, SF)

Brandon Aiyuk popped off against the Cardinals for eight catches for 147 yards on a season-high 12 targets. Most encouragingly, after a slow start due to the contract dispute, Aiyuk was up to 92% of snaps, which led all skill players for San Francisco.

George Kittle (TE, SF)

George Kittle has scored a touchdown in three straight games he played (he missed Week 3). In that time, he does not have fewer than four catches and 45 yards in any contest. As Brock Purdy's new favorite target, Kittle now has the second-best target share among tight ends (25.4%).

Kenneth Walker III (RB, SEA)

Just five rush attempts for Kenneth Walker III in a week after he scored three touchdowns seems almost criminal. But that's what he got on Sunday. He did receive eight targets and caught seven balls. Give him that usage in the passing game plus his routine 18-20 carries, and we could be talking about one of the best backs in all of fantasy football.

DK Metcalf (WR, SEA)

How has DK Metcalf earned his WR17 spot in half-PPR formats? Inconsistency, if we are being honest. His finishes by week so far have been: 2.9, 18.9, 16.4, 8.4, and 3.5. Still, we have to rely on the usage and trust that production will come. Metcalf is eighth in targets, fourth in routes run, fifth in air yards, and fourth in overall receiving yards.

 

Solid Starts for Fantasy Football Lineups

Jaxon Smith-Njigba (WR, SEA)

There is no doubt that JSN is a full-time player and is now an integral part of this Seattle offense. He is second on the team in targets with 40, just three behind Metcalf. However, it's been a roller coaster to get there. JSN has two games with 12 or more targets and two games with three or fewer.

Before he can graduate to must-start status in all leagues, there needs to be some consistency and touchdown upside. His four red-zone targets this year certainly help there.

Tyler Lockett (WR, SEA)

Tyler Lockett has taken a backseat to Smith-Njigba this season, but he is still routinely putting up flex-worthy performances. In only one game this season does Lockett not have at least five receptions or 75 yards.

Geno Smith (QB, SEA)

Why has Geno Smith ascended to a top-7 quarterback in fantasy football this season? He only has one game below 18 fantasy points this season. Smith leads the NFL in attempts, completions, and passing yards thanks to a new offense installed by Mike Macdonald.

He only has five passing touchdowns this year, but with this kind of volume, that is sure to change in the weeks ahead.

 

Consider Sitting for Fantasy Football Lineups

Jauan Jennings (WR, SF)

With just four targets and one catch on Sunday, what many feared might happen did occur when all of San Francisco's pass-catchers returned. Jennings dominated for two weeks while the 49ers battled injuries, but in Week 5, he played just half of their snaps.

Noah Fant (TE, SEA)

Despite a decent amount of preseason hype, Noah Fant is currently TE26 through five weeks. He has scored more than 3.9 fantasy points in half-PPR formats just once in five weeks.

Zach Charbonnet (RB, SEA)

Since playing more than 90% of the snaps in Weeks 2 and 3 when Kenneth Walker III was hurt, Charbonnet has reverted back into a part-time player. He was in on just 36% of Seattle's snaps on Sunday, and Walker also stole eight targets away from him in that game as well.

 

Kirksey’s Thursday Night Football Picks

Current Spread: San Francisco -3.5, Total: 47.5

Even this early in the season, the San Francisco 49ers -- who are the better team -- simply cannot fall two games behind Seattle in the division. Even more than that, they cannot give Seattle the advantage on the tiebreaker considering how competitive this division seems to be.

In the end, Seattle's defense is pushed to its ultimate limits by the plethora of playmakers on the 49ers. For the second week in a row, we get a shootout on Thursday Night Football.

The pick for Thursday Night Football this week is a desperate San Francisco 49ers team wins on the road, 30-24.

The Pick: San Francisco -3.5, OVER 47.5

2024 Record:
Spread (3-2), Over/Under (3-2)



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Pierceson Coody

Looks to Get Back on Track in First Players Appearance
Daniel Berger

Presses On at The Players Championship
Joshua Baez

Cardinals Send Joshua Baez to Minor-League Camp
Alvin Kamara

Teams Monitoring Alvin Kamara's Availability for Trade
Cedric Mullins

Chandler Simpson, Cedric Mullins Expected to Play Tuesday
Joey Wentz

Suffers Season-Ending Torn ACL
Min Woo Lee

an Intriguing Option at the Players
Sahith Theegala

Looks to Continue Strong Form at the Players
Jonathan Kuminga

in Danger of Missing Third Consecutive Game
John Collins

Won't Play This Week
Quinten Post

Starting Monday Night
DeMar DeRozan

Overcomes Illness, Available Tuesday
LeBron James

Listed as Questionable for Tuesday
Payton Pritchard

Iffy to Face Spurs Tuesday
Jason Day

Needs to Find Form Again at Players Championship
Patrick Cantlay

Hasn't Found Consistency This Season
Jakob Poeltl

Questionable for Matchup With Rockets
Grayson Allen

Could Miss Another Game Tuesday
Kevin Porter Jr.

to Remain Out Tuesday
Elmer Rodríguez

Yankees Reassign Elmer Rodriguez to Minor-League Camp
Kyle Kuzma

Available Against Suns Tuesday
Giannis Antetokounmpo

Ready for Action Tuesday
Keyonte George

Available Against Warriors
Isaiah Collier

Misses Monday's Game Due to Illness
Rico Dowdle

Steelers Signing Rico Dowdle on Monday
Spencer Jones

Yankees Send Spencer Jones to Minor-League Camp
Taylor Hendricks

Downgraded to Out
Ty Jerome

Scotty Pippen Jr. Sit Out Monday's Game
Cedric Coward

Out on Monday
Chet Holmgren

Unavailable Monday
Jesús Luzardo

Jesus Luzardo, Phillies Agree on Five-Year Extension
Ace Bailey

Ruled Out Against Golden State
Jamal Murray

Good to Go Monday
Cameron Payne

Starts Against Cavaliers
Logan Henderson

Dealing With Mild Elbow Soreness
LeBron James

Sits Out Practice on Monday
Corbin Carroll

Could Make Spring Debut This Week
James Reimer

Starting Monday Night
Jacoby Brissett

Cardinals Plan to Keep Jacoby Brissett as Their Starting QB
Joel Hanley

Returns to Action Against Capitals
Tua Tagovailoa

Plans to Sign One-Year Deal With Falcons
Evander Kane

Brock Boeser, Evander Kane Iffy Monday
Travis Kelce

Officially Re-Signs With Chiefs
Spencer Knight

Out Against Mammoth
Jaden Schwartz

Out Indefinitely
Brad Marchand

to Miss "Weeks"
Jake Sanderson

Considered Week-to-Week
J.K. Dobbins

Broncos Agree on Two-Year Deal to Bring J.K. Dobbins Back
Bryce Eldridge

to Begin Season at Triple-A?
Triston Casas

Won't Play in Any Grapefruit League Games
Max Holloway

Drops Decision At UFC 326
Mike Evans

Agrees to Join the 49ers
Evan Carter

to See Full-Time At-Bats?
Charles Oliveira

Becomes The New BMF Champion
Caio Borralho

Bounces Back
Wan'Dale Robinson

Signing With Titans
Reinier de Ridder

Reinier De Ridder Loses Back-To-Back Fights
Kevin McGonigle

Still in Big League Camp After Latest Roster Cuts
Rob Font

Gets Dominated
Raul Rosas Jr.

Extends His Win Streak
Max Clark

Reassigned to Minor-League Camp
Travis Etienne Jr.

Saints Signing Travis Etienne Jr.
Michael Johnson

Suffers Second-Round Knockout Loss
Drew Dober

Knocks Out Michael Johnson
Tyler Allgeier

Cardinals Agree on Two-Year Deal With Tyler Allgeier
Kenneth Gainwell

Signing Two-Year Deal With Buccaneers
Isaiah Likely

Giants Signing Isaiah Likely to Three-Year Deal
Malik Willis

Dolphins Signing Malik Willis to a Three-Year Deal
Michael Pittman Jr.

Steelers Acquire Michael Pittman Jr. From the Colts
Kenneth Walker III

Signing With the Chiefs
J.P. Crawford

Back at Shortstop on Monday
Alec Pierce

Returning to Colts on Four-Year Deal
Rafael Devers

Back in Cactus League Lineup on Monday
Tua Tagovailoa

Falcons Expected to Make a "Strong Push" for Tua Tagovailoa
Ryan Blaney

Earns his Second Consecutive Phoenix Cup Series Win
Christopher Bell

Falls Short of Victory Despite Dominating at Phoenix
Kyle Larson

Earns Hard-Fought Finish of Third at Phoenix
Denny Hamlin

Quietly Gains Another Top-Five Finish at Phoenix
Joey Logano

Crashes out at Phoenix Despite Strong Run
Zack Gelof

Making Cactus League Debut on Monday
Travis Kelce

Expected to Return to Chiefs in 2026
Josh Hader

to Throw a Bullpen on Tuesday
Minkah Fitzpatrick

Traded to Jets
Nick Seeler

Could Return Monday
Travis Konecny

a Game-Time Call Monday
Tua Tagovailoa

to be Released by Dolphins
Taylor Raddysh

to Miss Two Games
John Gibson

"Should Be Fine" After Early Exit Sunday
Oliver Moore

Ruled Out for Monday
Jaxon Wiggins

Optioned to Minor-League Camp
Gabriel Landeskog

Out Week-to-Week
Jonathon Long

Nearing Return to Baseball Activities
Leo De Vries

Crushes Two Home Runs on Sunday
Didier Fuentes

Strikes Out Four in Spring Debut
Tage Thompson

Picks Up Four Points Against Lightning
Trent McDuffie

Signs Record Four-Year, $124 Million Extension With Rams
Moritz Seider

has Three-Point Performance on Sunday
Emil Lilleberg

to Miss Two Weeks Due to Facial Fracture
Spencer Knight

Won't Play Sunday
John Carlson

Not Ready for Ducks Debut Sunday
Zach Whitecloud

Injured Saturday Night
Jaden Schwartz

Forced to Exit Early After Taking Skate Blade to Face
Jake Sanderson

Sustains Upper-Body Injury Versus Kraken
Ryan Blaney

is Always A Top Favorite to Compete for the Win At Phoenix
Denny Hamlin

Is Denny Hamlin Worth Rostering for Phoenix?
Christopher Bell

is Likely to have Another Solid Phoenix Run
Chase Briscoe

has Plenty of Upside for DFS Lineups at Phoenix
Joey Logano

Could Dominate at Phoenix This Weekend
Chase Elliott

has Plenty of Upside for Sunday's Race at Phoenix
Chris Buescher

Is Chris Buescher Worth Rostering For Phoenix DFS Lineups?
Ross Chastain

Has Found Speed Again at Phoenix
Josh Berry

a Solid Sleeper at Phoenix
Brad Keselowski

Skips Qualifying After Practice Crash at Phoenix
Tyler Reddick

Spins in Practice at Phoenix
William Byron

Should Be a Contender at Phoenix
Kyle Larson

Is Always a Threat at Phoenix
NASCAR

Could Bubba Wallace Be Playable for Phoenix DFS Lineups?
Anthony Alfredo

Is A Favorable DFS Option In A Substitution Role At Phoenix
Max Holloway

A Favorite At UFC 326
Charles Oliveira

Set For BMF Title Fight
Reinier de Ridder

Reinier De Ridder Looks To Bounce Back
Caio Borralho

Set For UFC 326 Co-Main Event
Rob Font

Looks To Get Back In The Win Column
Raul Rosas Jr.

Looks For His Fifth Consecutive Win
Drew Dober

Returns At UFC 326
Michael Johnson

Looks To Extend His Win Streak
Taylor Moore

Looking to Build on Cognizant Classic Finish
Robert MacIntyre

Brings Solid Form to Bay Hill
Scottie Scheffler

the Tournament Favorite at Bay Hill
Xander Schauffele

Trending Well Ahead of API
Si Woo Kim

Looking to Return to Top Form at Bay Hill
Ben Griffin

Looking to Return to Form at Arnold Palmer Invitational
PGA

Nico Echavarria Looks to Build on Cognizant Classic Win at Arnold Palmer
Sam Burns

Searching for Consistency at Arnold Palmer Invitational
Daniel Berger

Offers Sneaky Upside at Bay Hill
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF