👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


Bills vs Rams Start 'Em, Sit 'Em: Cam Akers, Darrell Henderson, Dawson Knox, Devin Singletary, James Cook, Isaiah McKenzie

Cooper Kupp - Fantasy Football Rankings, NFL Injury News, Draft Targets

Fantasy football start em, sit em and lineups advice for the Bills vs Rams Thursday Night game in Week 1 (2022). TNF matchups analysis with detailed breakdowns.

Football season is back! It's been 208 days since the Super Bowl and we start the season off with a barn burner. After an entire off-season drooling over Josh Allen's latest playoff performance, we get to see how he would have faired against the reigning Super Bowl Champions.

The table is set for an excellent start to the season. Despite falling two games short of the Super Bowl, the Bills have gained steam throughout the offseason. Heading into the season they are the favourites for the title at +600. Although impressive, what's with the disrespect to the Rams? Coming in at the fifth-best odds to win it all, they have double the Bills' odds at +1200. I can't imagine that sits well with the reigning champions and should fuel the fire for a great game.

For the third consecutive year, my name is Ellis Johnson and welcome to your Thursday Night Preview article. I will be writing this column all season, providing fantasy player analysis and game-betting picks. I want to thank RotoBaller for once again giving me this opportunity. I hope y'all are ready - cause football is back baby!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Buffalo Bills @ Los Angeles Rams - 8:20 pm ET 

Notable Injuries

 

Must-Starts for Fantasy Football Lineups

Cooper Kupp (WR, LAR)

How could I not start this article with the player who recorded arguably the greatest receiving season of all time? Kupp was truly magnificent last year, and although Justin Jefferson has gained momentum to be the WR1 overall, Kupp is still the best receiver in fantasy. Thankfully for him, nothing really changed with this team. Outside of bringing in Allen Robinson and the health of the running backs, the recipe for success is still there. Buffalo does have a formidable defense, but Kupp will find a way to impress, once again, for fantasy.

Josh Allen (QB, BUF)

I don't think I remember a player getting this much love all off-season. Even compared to the historic seasons of Joe Burrow and Cooper Kupp, Allen is the darling of 2022. After back-to-back QB1 overall finishes, everything is ready for him to three-peat. If there is one coach and player combo that could potentially slow down the Josh Allen rocket ship, it might be Sean McVay and Aaron Donald. However, you start your stars, and Allen is certainly one of those.

Stefon Diggs (WR, BUF)

If you've been following my work this offseason, you might know I am a little colder on Diggs than the rest of the analysts. However, he is still a top-tier player on an amazing offense. This game has everything set up to be a high-scoring back and fourth matchup. In which case, Diggs is the go-to target for Allen and should have a very good fantasy day, despite Jalen Ramsey potentially covering him.

 

Solid Starts for Fantasy Football Lineups

Matthew Stafford (QB, LAR)

Despite finishing as the seventh-best QB in fantasy last year, Stafford was fairly underwhelming. To give him credit, his consistency was excellent on a weekly basis, however, he failed to deliver week-winning performances - only cracking 25 points twice. Plus, the elbow wear and tear is a little concerning for this season but should have no impact for Week 1. I'd start Stafford as a low-end QB1, in case he has to keep up with Josh Allen and company.

Allen Robinson and Gabriel Davis (WR, LAR and BUF)

I don't typically combine players from different teams in my analysis, but these two are very similar. Despite being at vastly different points of their careers, all the offseason buzz was been identical. Both of these players are staring down a breakout/comeback season in 2022.

There was no shortage of camp videos showcasing both of these players' elite talents and red zone efficiency. It is this efficiency that makes me like them both for Week 1. In a game that could easily become a shootout, both these players could play a large role early on in the game. I'd play them both as high-end flex options to start the season.

Dawson Knox (TE, BUF)

Touchdown or bust is Knox's fantasy motto. Which, given the current TE landscape, is not the worst when you're attached to Josh Allen. Last year Knox was the TE7 with nine touchdowns, however, finished 15th at the position in yards. If you managed to scoop him up in your drafts he is a fine play, but you really need to hope he finds pay dirt to pay off.

 

Flex Considerations for Fantasy Football Lineups

Cam Akers and Darrell Henderson Jr. (RB, LAR)

To me, these are the definition of high upside flex plays in Week 1. Despite both struggling with their own injuries this offseason, it has come out that this will be a split backfield. This is something that we've never seen with Sean McVay, so we have no idea what the exact split could be. We also know that the last time we saw Akers on the field he was struggling to average more than three yards per carry.

If possible, I would love to wait a week and see what each player's roles are in the offense before starting them. Especially in this matchup against what could be a tough Bills run defense. However, I understand not everyone will have that choice and will be banking on them as a flex play and hoping for either back to find pay dirt.

What may be surprising to some, is that I do not have a strong preference on who I would play if both are fully healthy. Logically, the answer should be Akers, but there hasn't been anything out of camp and preseason that moves the needle for me.

 

Consider Sitting for Fantasy Football Lineups

Tyler Higbee (TE, LAR)

It's probably not a surprise that the fourth Rams passing option finds himself as a "sit" this week. Last year was very disappointing for the veteran TE, which fits right in with his fantasy career. Despite entering the NFL with legal issues, Higbee was considered a promising prospect when drafted by the Rams.

However, outside of a five-game stretch in 2019, he has not found success in McVay's system. There are no signs of this changing in 2022, and I don't think he should be rostered in typical redraft formats.

Devin Singletary and James Cook (RB, BUF)

Much like my analysis of the Rams running backs, the Bills also scare me. The main difference is that the Bills also have Josh Allen vulturing touchdowns on the goalline. Out of camp, Singletary has been the clear lead back, however, Cook has dominated as a pass catcher.

Unfortunately, over the last four years, the Bills have been in the bottom seven in the league in targets to the RB. I'd start Singletary well before Cook, but I'd like to see them both in action before putting them in my lineup.

Van Jefferson (WR, LAR)

Currently Jefferson is supposed to be healthy for Week 1. If that is the case, I think he is being forgotten about as the deep threat option on one of the league's best passing offenses. We saw last year that Jefferson flashed big-play ability as was a fine three for this team. Now with Robinson in town, he is presumed the three in Week 1, even though he has a history with Stafford.

I have more confidence in the usage of Robinson, but I wouldn't be surprised if Jefferson springs a long touchdown and has a very nice fantasy day. My only concern is that it's his first game back from his knee surgery, making him more of a high-risk desperation flex.

Isaiah McKenzie (WR, BUF)

If you want to shoot for the moon, you found your guy. Despite the hype around him after he surpassed Jamieson Crowder for the Cole Beasley role, I don't think he is startable in regular redraft leagues. In the past, McKenzie has flashed impressive athletic ability when Allen looks his way.

His fantasy production has also closely followed the health of Cole Beasley. Now that Beasley is gone, this could mean McKenzie has fantasy value. However, I'd wait a week and scoop him up if he sees five or more targets in Week 1.

Rams DST and Bills DST

Despite these two teams having some of the best defenses in the league, it's a scary first week for both teams. If you drafted them early, then you might be stuck with them which isn't the worst. With playmakers on both sides of the ball, each team could collect enough sacks to have a productive day, however, this game's 52.5 over-under worries me.

 

Ellis’ Picks

Bills -2.5 (0-0), Under 52.5 (0-0)

Last season we gained some ground on the picks going over 500 in both categories. This year we start with two high-powered teams with high-flying defenses. It's always tough picking Week 1 games, and it's a matter of which side of the ball may come out a little flat.

With only a 2.5-point spread, I view this as similar to a pick'em, making it an easy choice. As for the over-under, 52.5 points seems inflated from all the Bills buzz this offseason. As a result, these picks seem pretty logical to me. Catch me next week when we have an absolute heater of a matchup. Chiefs vs. Chargers - I'll see you there!

Career record: Spread (22-14), Over/Under (21-15)



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Analysis




REAL-TIME FANTASY NEWS

Pat Bryant

Working With Training Staff This Offseason
Jacoby Brissett

in Communication With Cardinals Despite Skipping Workouts
Daniel Jones

Could Take Part in 7-on-7 Drills at OTAs
Tyler Glasnow

Dodgers Put Tyler Glasnow on Injured List With Back Spasms
Sam Merrill

Iffy for Game 3 on Saturday
Anthony Edwards

Rejoins Starting Lineup Friday
Kevin Huerter

Likely to Remain Out Saturday
Jarred Vanderbilt

Considered Questionable for Saturday
Jalen Williams

Ruled Out for Game 3 Against Lakers
Ayo Dosunmu

Cleared to Play Friday
Anthony Edwards

Available Friday Night
Joel Embiid

is Returning for Game 3 on Friday
Brandon Ingram

Undergoes Heel Surgery
Josh Hart

is Available to Play in Game 3
OG Anunoby

is Downgraded to Out for Game 3 on Friday
Mitchell Robinson

is Returning for Game 3
Mats Zuccarello

Expected to Play Saturday
Joel Eriksson Ek

to Be a Game-Time Decision Saturday
Jonas Brodin

Still Out Saturday
Josh Manson

Could Return Saturday
Kaedan Korczak

Scratched for Game 3 Against Ducks
Radko Gudas

Likely to Remain Out Friday
Sam Carrick

Won't Play Friday
Isiah Pacheco

Can Isiah Pacheco Re-Establish His Dynasty Value in Detroit?
Rico Dowdle

Dynasty Ceiling Limited By Backfield Committee in Pittsburgh
Rashid Shaheed

a High-Risk, High-Reward Buy-Low Candidate for Dynasty Managers
Marcus Mariota

Is Marcus Mariota Worth Stashing as an Injury Replacement in Dynasty Leagues?
Jacoby Brissett

a Clear Sell-High Candidate for Dynasty Managers
Blake Snell

to Make Season Debut for Dodgers on Saturday
Najee Harris

Can Najee Harris Re-Establish Some Dynasty Value in 2026?
Cole Ragans

Royals Place Cole Ragans on Injured List With Elbow Impingement
Breece Hall

Jets Sign Breece Hall to Three-Year Extension Worth $45.75 Million
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
Nick Lodolo

Officially Activated, Making Season Debut on Friday
Denver Broncos

Broncos Sign GM George Paton to New Five-Year Deal
Brandon McManus

Packers Release Kicker Brandon McManus
New York Jets

Jets Talking to a "Number of Veteran Quarterbacks"
Travis Etienne Jr.

a Reliable Dynasty Starter Entering First Season With Saints
Kenneth Gainwell

Is Kenneth Gainwell's Dynasty Stock Still Rising After Offseason Change of Scenery?
Mac Jones

a Deep-League Dynasty Stash Candidate
Tez Johnson

Facing Uphill Battle for Playing Time in Tampa Bay
Jared Goff

Remains a High-Floor Dynasty QB2 Heading into 2026
De'Von Achane

Remains a High-End Dynasty RB Despite Uncertain Supporting Cast
Xavier Worthy

Chiefs Limited Xavier Worthy's Usage After Injury Last Year
Rashee Rice

Chiefs Not Ready to Discuss Extension With Rashee Rice?
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
Austin Reaves

Scores 31 Points in Game 2 Defeat
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
Chet Holmgren

Anchors Thunder Past Lakers in Game 2
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
Tobias Harris

Stays Hot in Game 2 Victory
Cade Cunningham

Pushes Pistons to 2-0 Series Lead
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
Jarrett Allen

Provides Bright Spot in Cavs' Game 2 Loss to Pistons
CFB

Rasheem Biles an Instant Impact Player for Texas
James Harden

Struggles in Game 2 Loss
Donovan Mitchell

Finishes Game 2 Loss with 31 Points
Gradey Dick

Open to Trade Away From Toronto
Michael Porter Jr.

Wants to Stay in Brooklyn
Dan Vladar

Looks to Return to Winning Ways Thursday
Connor Dewar

Penguins Re-Sign Connor Dewar for Two Years
Mikko Rantanen

Played Through Torn MCL Late in the Season
Rasmus Dahlin

Ready to Go Friday
Alexander Nikishin

Set to Return Thursday
Christian Dvorak

Available Thursday
Owen Tippett

Remains Out Thursday
Roman Anthony

Heading for the Injured List
CFB

Sam Leavitt Expected to Be Full-Go for Fall Camp
Tarik Skubal

Could Return in 4-6 Weeks After Successful Elbow Surgery
Cole Ragans

Royals Hopeful That Cole Ragans Makes his Next Start
Mark Stone

Nets Late Power-Play Goal in Losing Effort
Leo Carlsson

Pots Game-Winner Wednesday Night
Juraj Slafkovsky

Ends Point Drought in Game 1 Loss
Bowen Byram

Ties Franchise Record With Fourth Postseason Goal
Zach Benson

Posts Second Consecutive Multi-Point Game
Rasmus Dahlin

"Seems Fine" After Early Exit on Wednesday
Emilio Pagán

Emilio Pagan has Grade 2 Hamstring Strain, Expected to Miss 4-8 Weeks
Joe Ryan

Listed as Scheduled Starter for Saturday Against Cleveland
Tyler Glasnow

Not Expected to Land on the Injured List
Framber Valdez

Suspension Reduced to Five Games
Nils Hoglander

Will Miss World Championship Due to Injury
Framber Valdez

Suspended Six Games
Tyler Glasnow

Exits Early on Wednesday With Back Pain
CFB

Brauntae Johnson the Next Star in Notre Dame's Secondary?
CFB

Ethan Barbour a Name to Know in Georgia's Tight End Room
CFB

Payton Pierce Next Up at Linebacker for Ohio State
CFB

Javin Gordon to Play Significant Role for Tennessee?
CFB

Tanook Hines Stepping into WR1 Role for USC
CFB

Rueben Owens II has "Star Potential" in Fourth Campaign
Brandon Woodruff

has Fluid Drained From his Right Shoulder
Brandon Woodruff

to Resume Throwing on Saturday, Return Imminent?
Carlos Correa

to Have Season-Ending Ankle Surgery
Jacob Misiorowski

Listed as Friday's Probable Starter
Logan Webb

Dealing With Knee Discomfort
Carlos Correa

Expected to Miss Significant Time With Ankle Injury
Collin Morikawa

Withdraws From Truist Championship
Xander Schauffele

Carries Elite Form Into Quail Hollow
Hideki Matsuyama

Looks to Bounce Back at Truist Championship
Matt Fitzpatrick

Secures Third Win of 2026 Season
Patrick Cantlay

Continues Playing Well Heading to Truist Championship
Ludvig Aberg

Returns to Action For Truist Championship
Justin Thomas

Searching for Consistency at Quail Hollow
Jordan Spieth

Looks to Break Through at Quail Hollow
Adam Scott

Brings Strong Form to Quail Hollow
Robert MacIntyre

a Steady Option at Truist Championship
Jason Day

Looks to Overcome Approach Struggles at Quail Hollow
Akshay Bhatia

Looks for Complete Game at Truist Championship
Emilio Pagán

Emilio Pagan Headed for Injured List With Hamstring Injury
Emilio Pagán

Emilio Pagan Carted Off With Apparent Hamstring Injury on Tuesday
Justin Rose

to Continue Mid-Season Club Change at Truist Championship
Si Woo Kim

is Back to Peak Form Ahead of Truist Championship
Sam Burns

to Bounce Back at Truist Championship
Cameron Young

Looks to Carry Dominance to Quail Hollow
Rory McIlroy

Returns to Familiar Stomping Grounds This Week at Quail Hollow
Chris Gotterup

Looking to Bounce Back at Quail Hollow
Tommy Fleetwood

Looking For Better Iron Play at Quail Hollow
CFB

Mario Craver Enters No. 1 Wide Receiver Role for Marcel Reed
CFB

LaNorris Sellers a Strong Rebound Candidate in 2026
CFB

Cam Coleman Poised for Monster Year at Texas?
CFB

Will Hammond Pushing to Be Ready for Week 1
Alex Fitzpatrick

Looking to Keep Up Ball-Striking Output at Quail Hollow
CFB

Notre Dame Leads College Football in Returning Snaps
CFB

Two Ole Miss Football Players Arrested, Charged with DUI
Ben Griffin

Looks Solid on the Surface Heading to Charlotte
Chase Elliott

Earns his Second Texas Motor Speedway Victory
Denny Hamlin

Misses Out on Winning at Texas
Alex Bowman

Finishes Third for the Second Week in a Row at Texas
Tyler Reddick

Earns Seventh Top-Five Finish of the Season at Texas
Chris Buescher

Scores his First Career Texas Finish in the Top Five
CFB

Bryce Underwood in Better Situation Entering Sophomore Season
CFB

Nico Iamaleava Emerging as Leader, Playmaker for UCLA
Jack Della Maddalena

Gets Dominated At UFC Perth
Carlos Prates

Shines At UFC Perth
Beneil Dariush

Suffers A First-Round TKO Loss
Quillan Salkilld

Remains Unbeaten In The UFC
Tim Elliott

Drops Decision At UFC Perth
Steve Erceg

Wins Back-To-Back Fights
Ollie Schmid

Suffers First-Round TKO Loss
Marwan Rahiki

Remains Unbeaten
Christopher Bell

Is Christopher Bell Worth Rostering for Texas Lineups?
William Byron

Might have the Speed to Compete for the Win at Texas
Joey Logano

Provides Solid Upside for Texas DFS Lineups
Chase Briscoe

Could Chase Briscoe be A Sneaky Pick for Texas Lineups?
Ty Gibbs

Should DFS Managers Roster Ty Gibbs at Texas?
Daniel Suarez

Is Daniel Suarez Worth Rostering After Career-Best Starting Position at Texas?
Kyle Busch

Is a DFS Risk Starting in the Top 10 at Texas
Tyler Reddick

One of the Favorites to Win at Texas
Chase Elliott

Could Contend for Another Win at Texas
Carson Hocevar

on Pole at Texas
NASCAR

Bubba Wallace Wrecks in Practice at Texas
Chris Buescher

Looking to Continue Strong Run at Texas
Austin Dillon

Blows Engine in Practice at Texas
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF