👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

Bills vs Rams Start 'Em, Sit 'Em: Cam Akers, Darrell Henderson, Dawson Knox, Devin Singletary, James Cook, Isaiah McKenzie

Cooper Kupp - Fantasy Football Rankings, NFL Injury News, Draft Targets

Fantasy football start em, sit em and lineups advice for the Bills vs Rams Thursday Night game in Week 1 (2022). TNF matchups analysis with detailed breakdowns.

Football season is back! It's been 208 days since the Super Bowl and we start the season off with a barn burner. After an entire off-season drooling over Josh Allen's latest playoff performance, we get to see how he would have faired against the reigning Super Bowl Champions.

The table is set for an excellent start to the season. Despite falling two games short of the Super Bowl, the Bills have gained steam throughout the offseason. Heading into the season they are the favourites for the title at +600. Although impressive, what's with the disrespect to the Rams? Coming in at the fifth-best odds to win it all, they have double the Bills' odds at +1200. I can't imagine that sits well with the reigning champions and should fuel the fire for a great game.

For the third consecutive year, my name is Ellis Johnson and welcome to your Thursday Night Preview article. I will be writing this column all season, providing fantasy player analysis and game-betting picks. I want to thank RotoBaller for once again giving me this opportunity. I hope y'all are ready - cause football is back baby!

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

 

Buffalo Bills @ Los Angeles Rams - 8:20 pm ET 

Notable Injuries

 

Must-Starts for Fantasy Football Lineups

Cooper Kupp (WR, LAR)

How could I not start this article with the player who recorded arguably the greatest receiving season of all time? Kupp was truly magnificent last year, and although Justin Jefferson has gained momentum to be the WR1 overall, Kupp is still the best receiver in fantasy. Thankfully for him, nothing really changed with this team. Outside of bringing in Allen Robinson and the health of the running backs, the recipe for success is still there. Buffalo does have a formidable defense, but Kupp will find a way to impress, once again, for fantasy.

Josh Allen (QB, BUF)

I don't think I remember a player getting this much love all off-season. Even compared to the historic seasons of Joe Burrow and Cooper Kupp, Allen is the darling of 2022. After back-to-back QB1 overall finishes, everything is ready for him to three-peat. If there is one coach and player combo that could potentially slow down the Josh Allen rocket ship, it might be Sean McVay and Aaron Donald. However, you start your stars, and Allen is certainly one of those.

Stefon Diggs (WR, BUF)

If you've been following my work this offseason, you might know I am a little colder on Diggs than the rest of the analysts. However, he is still a top-tier player on an amazing offense. This game has everything set up to be a high-scoring back and fourth matchup. In which case, Diggs is the go-to target for Allen and should have a very good fantasy day, despite Jalen Ramsey potentially covering him.

 

Solid Starts for Fantasy Football Lineups

Matthew Stafford (QB, LAR)

Despite finishing as the seventh-best QB in fantasy last year, Stafford was fairly underwhelming. To give him credit, his consistency was excellent on a weekly basis, however, he failed to deliver week-winning performances - only cracking 25 points twice. Plus, the elbow wear and tear is a little concerning for this season but should have no impact for Week 1. I'd start Stafford as a low-end QB1, in case he has to keep up with Josh Allen and company.

Allen Robinson and Gabriel Davis (WR, LAR and BUF)

I don't typically combine players from different teams in my analysis, but these two are very similar. Despite being at vastly different points of their careers, all the offseason buzz was been identical. Both of these players are staring down a breakout/comeback season in 2022.

There was no shortage of camp videos showcasing both of these players' elite talents and red zone efficiency. It is this efficiency that makes me like them both for Week 1. In a game that could easily become a shootout, both these players could play a large role early on in the game. I'd play them both as high-end flex options to start the season.

Dawson Knox (TE, BUF)

Touchdown or bust is Knox's fantasy motto. Which, given the current TE landscape, is not the worst when you're attached to Josh Allen. Last year Knox was the TE7 with nine touchdowns, however, finished 15th at the position in yards. If you managed to scoop him up in your drafts he is a fine play, but you really need to hope he finds pay dirt to pay off.

 

Flex Considerations for Fantasy Football Lineups

Cam Akers and Darrell Henderson Jr. (RB, LAR)

To me, these are the definition of high upside flex plays in Week 1. Despite both struggling with their own injuries this offseason, it has come out that this will be a split backfield. This is something that we've never seen with Sean McVay, so we have no idea what the exact split could be. We also know that the last time we saw Akers on the field he was struggling to average more than three yards per carry.

If possible, I would love to wait a week and see what each player's roles are in the offense before starting them. Especially in this matchup against what could be a tough Bills run defense. However, I understand not everyone will have that choice and will be banking on them as a flex play and hoping for either back to find pay dirt.

What may be surprising to some, is that I do not have a strong preference on who I would play if both are fully healthy. Logically, the answer should be Akers, but there hasn't been anything out of camp and preseason that moves the needle for me.

 

Consider Sitting for Fantasy Football Lineups

Tyler Higbee (TE, LAR)

It's probably not a surprise that the fourth Rams passing option finds himself as a "sit" this week. Last year was very disappointing for the veteran TE, which fits right in with his fantasy career. Despite entering the NFL with legal issues, Higbee was considered a promising prospect when drafted by the Rams.

However, outside of a five-game stretch in 2019, he has not found success in McVay's system. There are no signs of this changing in 2022, and I don't think he should be rostered in typical redraft formats.

Devin Singletary and James Cook (RB, BUF)

Much like my analysis of the Rams running backs, the Bills also scare me. The main difference is that the Bills also have Josh Allen vulturing touchdowns on the goalline. Out of camp, Singletary has been the clear lead back, however, Cook has dominated as a pass catcher.

Unfortunately, over the last four years, the Bills have been in the bottom seven in the league in targets to the RB. I'd start Singletary well before Cook, but I'd like to see them both in action before putting them in my lineup.

Van Jefferson (WR, LAR)

Currently Jefferson is supposed to be healthy for Week 1. If that is the case, I think he is being forgotten about as the deep threat option on one of the league's best passing offenses. We saw last year that Jefferson flashed big-play ability as was a fine three for this team. Now with Robinson in town, he is presumed the three in Week 1, even though he has a history with Stafford.

I have more confidence in the usage of Robinson, but I wouldn't be surprised if Jefferson springs a long touchdown and has a very nice fantasy day. My only concern is that it's his first game back from his knee surgery, making him more of a high-risk desperation flex.

Isaiah McKenzie (WR, BUF)

If you want to shoot for the moon, you found your guy. Despite the hype around him after he surpassed Jamieson Crowder for the Cole Beasley role, I don't think he is startable in regular redraft leagues. In the past, McKenzie has flashed impressive athletic ability when Allen looks his way.

His fantasy production has also closely followed the health of Cole Beasley. Now that Beasley is gone, this could mean McKenzie has fantasy value. However, I'd wait a week and scoop him up if he sees five or more targets in Week 1.

Rams DST and Bills DST

Despite these two teams having some of the best defenses in the league, it's a scary first week for both teams. If you drafted them early, then you might be stuck with them which isn't the worst. With playmakers on both sides of the ball, each team could collect enough sacks to have a productive day, however, this game's 52.5 over-under worries me.

 

Ellis’ Picks

Bills -2.5 (0-0), Under 52.5 (0-0)

Last season we gained some ground on the picks going over 500 in both categories. This year we start with two high-powered teams with high-flying defenses. It's always tough picking Week 1 games, and it's a matter of which side of the ball may come out a little flat.

With only a 2.5-point spread, I view this as similar to a pick'em, making it an easy choice. As for the over-under, 52.5 points seems inflated from all the Bills buzz this offseason. As a result, these picks seem pretty logical to me. Catch me next week when we have an absolute heater of a matchup. Chiefs vs. Chargers - I'll see you there!

Career record: Spread (22-14), Over/Under (21-15)



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Rachaad White

Is Rachaad White an Offseason Trade Target in Dynasty Leagues?
Jesper Wallstedt

to Start in Goal for Minnesota on Saturday
Stefon Diggs

Still a Free Agent Ahead of the NFL Draft
Trey Benson

Stuck in a Crowded Backfield
Jacory Croskey-Merritt

Year 2 Value Tied to Pick No. 7 in the NFL Draft
Sean Tucker

Dynasty Value Still Comes Primarily as an Injury Replacement
Jake Tonges

a Capable Fill-in for as Long as He Needs to Be
NFL

Ja'Kobi Lane Could Need Time to Develop for Fantasy Managers
Chig Okonkwo

Could Still Be Undervalued Despite Calls for a Breakout
LaMelo Ball

Scores 23 Points in Season-Ending Loss
Jordan Goodwin

Fills Stat Sheet in Play-In Win
Paolo Banchero

Powers Magic Into Playoffs
Jalen Green

Drops 36 Points to Clinch Playoff Spot
Amen Thompson

Off Injury Report for Playoff Opener
Jabari Smith Jr.

Cleared After Resting in Season Finale
Alperen Sengün

Alperen Sengun Cleared for Game 1 Against Lakers
Logan Stankoven

Presumed Ready for Game 1
NFL

First Round of NFL Draft Could Feature Plenty of Trades
Max Muncy

has Another Multi-Homer Game at Coors Field
Lourdes Gurriel Jr.

Expected to Make Season Debut on Saturday
Austin Riley

Hits Two Home Runs in Shutout Win Over Phillies
Daulton Varsho

Removed Early on Friday With Knee Discomfort
Rashawn Slater

Joe Alt Expected to Participate in Offseason Program
Aaron Gordon

Available for Game 1 Against Timberwolves
Julius Randle

Cleared for Playoffs
Jaxson Hayes

Available Saturday Night
Grayson Allen

Will Play Against Warriors
Kristaps Porzingis

Cleared for Friday's Game
Kevin Durant

Iffy for Saturday's Game 1
Mark Williams

Won't Play Friday Night
Spencer Jones

is Questionable for Game 1 on Saturday
Peyton Watson

is Ruled Out for Game 1 on Saturday
Edwin Uceta

Having More Shoulder Issues, "Shut Down for a Few Days"
Moussa Diabaté

Moussa Diabate is Available on Friday
Ayo Dosunmu

is Available for Saturday's Game
Anthony Edwards

Questionable for Saturday's Action
Jonathan Isaac

Remains Out Friday
NFL

Jeremiyah Love Considered the Top Overall Talent in 2026 NFL Draft?
Jarrett Allen

Removed From Injury Report Ahead of Playoffs
Aaron Jones Sr.

Role in Minnesota Could Continue to Decrease in 2026
Romeo Doubs

Appears Poised for Larger Role in New England
Isiah Pacheco

Is Isiah Pacheco a Worthy Buy-Low Target for Dynasty Managers?
Rico Dowdle

Will Rico Dowdle Emerge as the Clear RB1 in Pittsburgh?
Rashid Shaheed

Can Rashid Shaheed Establish a Higher-Volume Role in Seattle in 2026?
Marcus Mariota

Set for Backup Role in 2026
Josh Hader

Moved to 60-Day Injured List
Ruke Orhorhoro

Jaguars Acquire Ruke Orhorhoro From the Falcons
NFL

Jordyn Tyson Could Come Off the Board as Early as Fifth Overall
Willson Contreras

Returns to Red Sox Lineup on Friday
Daniel Palencia

Goes on 15-Day Injured List With Oblique Strain
Jacoby Brissett

Sitting Out Offseason Workouts, Asking for Extension
Will Anderson Jr.

Texans Agree to Three-Year Extension With Will Anderson Jr.
Juan Soto

Still on Track to Return Next Week
Los Angeles Angels

Garret Anderson Dies at 53 Years Old
Mike Malott

A Favorite At UFC Winnipeg
Gilbert Burns

Set For UFC Winnipeg Main Event
Kyler Phillips

Set UFC Winnipeg Co-Main Event
Charles Jourdain

Looks To Extend His Win Streak
Jai Herbert

An Underdog At UFC Winnipeg
Mandel Nallo

Set For His UFC Debut
Karine Silva

Looks To Get Back In The Win Column
Jasmine Jasudavicius

Looks To Bounce Back
Robert Thomas

Wraps Up Season With a Hat Trick
Macklin Celebrini

Establishes Sharks' New Scoring Record
Scott Wedgewood

Keeps Kraken From Scoring Thursday
Nathan MacKinnon

Wins Rocket Richard Trophy With 53 Goals
Connor McDavid

Secures Sixth Art Ross Trophy With Four-Assist Performance
Connor Dewar

Ready for Game 1
Nikita Grebenkin

Unavailable at Start of Playoffs
Parker Messick

Flirts With No-Hitter in Latest Gem Against Orioles
Mike Trout

Hits Five Homers in Series Versus Yankees
CGY

Arsenii Sergeev to Make NHL Debut Thursday
Aleksander Barkov

Cleared for World Championship
Pierre-Luc Dubois

Dealing With Fractured Hand
Zach Whitecloud

Ready to Rock Thursday
Matt Coronato

Available Against Kings
Josh Manson

Expected to Return for Postseason
Nathan MacKinnon

Martin Necas Sit Out Regular-Season Finale
Spencer Arrighetti

Fans 10 in Season Debut, to Remain a Focal Point in Rotation?
Nick Pivetta

Dealing With Flexor Strain, Could Miss Months
Nico Hoerner

Homers, Drive in Five in Win Over Phillies
Shota Imanaga

Strikes Out 11 in First Win of the Season
Sal Stewart

Continues to Hit, Goes Deep Twice on Wednesday
Shohei Ohtani

Strikes Out 10 in Win Over Mets
Connor Bedard

Has Two Assists in Season Finale
Claude Giroux

Sends Out Two Assists in Battle of Ontario Win
Tye Kartye

Registers First Career Three-Point Game
Owen Power

Records Two Assists Wednesday
Esa Lindell

Tallies Two Points in Regular-Season Finale
Shohei Ohtani

Will Pitch on Wednesday, But Won't DH
Nick Pivetta

Confident he'll Pitch Again This Year
Trevor Story

Carries Red Sox With Five RBI on Wednesday
CFB

Michigan Lands Commitment From Quarterback Kamden Lopati
Sahith Theegala

Brings Strong Form Into Harbour Town
Wyndham Clark

Needs Putter to Show Up at RBC Heritage
Jacob Bridgeman

Looks to Return to Elite Form at Harbour Town
J.J. Spaun

a Volatile Option at RBC Heritage
PGA

Sungjae Im Offers High-Upside Value at RBC Heritage
Matt Fitzpatrick

Set for Another Strong Showing at RBC Heritage
Jason Day

Eyes Bounce-Back After Sunday Struggles at the Masters
Akshay Bhatia

Looking to Rebound at Harbour Town
Cameron Young

Hoping to Secure Second Win of Season at RBC Heritage
Scottie Scheffler

Looks to Win Again at RBC Heritage
Shane Lowry

Has Disappointing Final Round at Masters
Viktor Hovland

Hoping to Build on Final Round at Masters
Brian Harman

Struggling For Consistency Heading to RBC Heritage
Chris Gotterup

Putting Together Outstanding 2026 Season
Justin Thomas

Looks to Defend in Hilton Head
Jordan Spieth

in Search of Improved Putting at RBC Heritage
Marco Penge

May Continue Up-and-Down Ride at the RBC Heritage
Xander Schauffele

Could Get The Job Done at RBC Heritage
Jake Knapp

Keeps Building Strong Results in 2026
Kurt Kitayama

Trying to Regain Form From Florida
Collin Morikawa

Continues to be a Scary DFS Play at RBC Heritage
CFB

Tramell Jones Jr. Outperforms Aaron Philo During Florida's Spring Scrimmage
CFB

Keelon Russell Flashes in Alabama's Spring Game
Ty Gibbs

Holds off the Field for His First Cup Series Victory at Bristol
Ryan Blaney

Earns His First Runner-Up Finish at Bristol
Kyle Larson

Dominant Performance At Bristol Falls Short of Victory
Tyler Reddick

Matches his Career-Best Finish at Bristol
Alex Bowman

Crashes Early at Bristol in Return From Injury
Carlos Ulberg

Is The New Light Heavyweight Champion
Jiří Procházka

Jiri Prochazka Suffers First-Round Knockout Loss
Azamat Murzakanov

Suffers His First Loss
Paulo Costa

Wins Back-to-Back Fights
Curtis Blaydes

Drops Decision At UFC 327
Josh Hokit

Remains Unbeaten
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF