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DraftKings Daily Fantasy Football Lineup Picks (Week 6): NFL DFS Advice

Welcome to RotoBaller's Daily Fantasy football DraftKings lineup picks for Week 6 of the NFL season. In this article, I, Jason Bales, will be taking you, the reader, through the best DraftKings DFS plays of the week for this upcoming Sunday.

These DraftKings lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 6. Good luck with your DraftKings DFS lineups!

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DraftKings Quarterbacks - Week 6 DFS Picks

Cam Newton (at NO, $8,100)

Cam Newton is recovering from a concussion, but it looks like he will be set to start for the Carolina Panthers this week against the New Orleans Saints. At home, Drew Brees is one of the best quarterbacks in the league, and the Panthers have been slipping since the beginning of the season. If they want to salvage their season, this is very close to a must win game. The Saints are going to score early and often. Newton is going to have to matchup them. The Saints' pass defense is horrendous, so the Panthers should not have too many issues finding open wide receivers, or tight ends. Newton has a rushing touchdown in two of his last four games, so fire him up due to his consistency and upside, in both 50/50 contests and tournaments.

 

DraftKings Running Backs - Week 6 DFS Picks

LeSean McCoy (vs SF, $6,900)

LeSean McCoy is one of the best running backs in the league right now. He has over 20 fantasy points in three straight games now, and this week, he gets a great matchup against the San Francisco 49ers and Chip Kelly's lightning speed offense. McCoy should have more carries and targets than he usually gets, and he has been producing with limited numbers. The Buffalo Bills are likely going to win this game, which means that McCoy will see a lot of carries in the fourth quarter. His price tag is very reasonable, and he has the upside of Le'Veon Bell and DeMarco Murray.

Carlos Hyde (at BUF, $5,100)

Carlos Hyde should not be used in the same lineup as LeSean McCoy, as both running backs are not likely going to see 20 plus carries, but he does make for a great roster move in tournaments. His upside is very high, as he has over 20 fantasy points in two of his last three starts. Against the Seattle Seahawks, a very tough rush defense, he posted 28.5 fantasy points on 21 carries. If he continues to get worked into the passing attack for the 49ers, he is going to be a semi-elite level running back within the next couple of weeks. His price tag is bound to come up at some point, so roster him while he is cheap.

 

DraftKings Wide Receivers - Week 6 DFS Picks

A.J. Green (at NE, $8,600)

A.J. Green has been fantastic so far this season with 36 receptions, 518 receiving yards, and two touchdowns. If he starts to find the end zone a little bit more frequently, he will quickly turn into a top five wide out. Two games ago, he posted over 35 fantasy points on 12 targets and 10 receptions. Unfortunately, he only does that every so often. In his last five starts, he has over 35 fantasy points twice. That upside is as high as Antonio Brown and Julio Jones, but his price tag is lower. The New England Patriots are going to score. The Bengals will be playing from behind, which should bode well for Green. After his poor performance last week, they should be attempting to get him involved in the game plan a little bit more often.

Jeremy Maclin (at OAK, $6,300)

According to Vegas, the Kansas City Chiefs are going to walk into Oakland and beat the Raiders. That is very surprising, but Vegas tends to know more than anyone else. Jeremy Maclin has been a very consistent fantasy option at the wide receiver position, so using him in 50/50 contests is the correct move. However, this week, he can also be used in tournaments. The Chiefs are going to have to score to beat the Raiders, and Maclin is their go-to target. He has over 10 fantasy points in three of his last four starts, and he only found the end zone once this season. Over 20 fantasy points is definitely possible, if he sniffs out the goal line early.

 

DraftKings Tight Ends - Week 6 DFS Picks

Coby Fleener (vs CAR, $3,500)

Coby Fleener is a very high-upside tight end option for tournaments this week against the Carolina Panthers. The Panthers are not good defensively against the tight end position, and Fleener recently posted over 25 fantasy points against the Atlanta Falcons. As previously mentioned, Drew Brees is outstanding at home, which increases Fleener's upside. He is starting to see more targets, and if the Saints are winning the game, he should see even more targets. The Saints tend to check down before running the ball. It is just how their offense works. Use Fleener in tournaments, but his consistency has not been there. As a side note, Vernon Davis (with Jordan Reed out of the Redskins' lineup) makes for a fantastic low-priced tight end option.

 




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REAL-TIME FANTASY NEWS

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a Horse for Course History at TPC San Antonio
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Misses Second Consecutive Game Tuesday
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Active on Tuesday
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Has One Flaw to Overcome at Valero Texas Open to be a Must-Play
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to Sit Out Tuesday's Game
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a Game-Time Decision Tuesday
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Ready for Action Tuesday
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Slated to Suit Up on Tuesday
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Rejoins Panthers Lineup Tuesday
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Has Successful Surgery on Tuesday
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Trending Toward Return
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Likely Sidelined for Two More Games
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the "Front-Runner" to be Top Backup RB
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Planning to Re-Sign With Steelers?
Seattle Seahawks

Mike Washington Jr. Would Fill a Big Need for Seahawks
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Kenyon Sadiq a Good Fit With the Rams?
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Packers to "Strip Everything Down" on Offense
Anthony Richardson Sr.

to Stay With Colts?
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Ty Simpson has Visits With Cardinals, Dolphins, Browns
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Mike McCarthy, Aaron Rodgers Touch Base
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Mechanical Tweaks are Focused on his Footwork
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to Play the Slot And Outside
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Withdraws From Valero Texas Open
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a Risky Proposition at Valero Texas Open
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Cleared for Season Debut on Tuesday
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James Conner

Role Threatened in Arizona?
Devin Neal

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Headed for More Targets in 2026?
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Still Has WR1 Upside in New Home
William Nylander

Records Four Points Against Ducks
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Jaden Schwartz

Could Return Tuesday
Jordan Greenway

Available Tuesday
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Remains Out Tuesday
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Exits Early Against Maple Leafs
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Sustains Upper-Body Injury Monday
Josh Minott

Active on Tuesday
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Available Against Mavericks
Kyle Kuzma

Probable Tuesday
Ryan Rollins

Likely to Return Tuesday
Bobby Portis

Remains Out Tuesday
Dillon Brooks

Ready to Return Tuesday
Patrick Rodgers

Needs to Make More Birdies in San Antonio
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Considered Week-to-Week
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Seeks Opportunity in San Antonio This Weekend
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Could Again Struggle at the Valero Texas Open
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Sets Up Solidly for TPC San Antonio
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Tallies Four Hits, Two Homers in Big Night
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has Three-Point Performance on Monday
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Good to Go Monday
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Draws Start Monday
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Returns Monday
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Out Vs. Cleveland
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Won't Play Tuesday
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Returns to Action Monday
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Ready to Face Maple Leafs
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to Remain Sidelined Monday
Matt McCarty

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Looking to Continue Form From The Players Championship
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Attempting to String Better Rounds Together at San Antonio
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Still Having Rough Time Contending at Events
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Looks to Get Back on Track at Valero Texas Open
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Takes Advantage of Pit Strategies for Second Career Martinsville Win
Denny Hamlin

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Joey Logano

Bounces Back with Third-Place Finish at Martinsville
Ty Gibbs

Gains his Fourth Top-Five Finish of the Season at Martinsville
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Scores Another Top-Five Finish at Martinsville
Joe Pyfer

Extends His Winning Streak
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Loses Fourth Consecutive Fight
Maycee Barber

Suffers Her First Knockout Loss
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Scores Highlight-Reel Knockout
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Christopher Bell

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is A Solid DFS Option for Martinsville Lineups
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Carlos Estevez Unlikely to See High-Leverage Opportunities in Near Future
Jacob deGrom

Feels "Much Better," Hopeful he Can Start This Week
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Should Fantasy Managers Roster Ty Gibbs at Martinsville?
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Is A Solid DFS Option for Martinsville Lineups
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Could Josh Berry Pay Off for Tournament DFS Lineups At Martinsville?
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Looks To Get Back In The Win Column
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In Dire Need Of Victory
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