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DraftKings Daily Fantasy Football Lineup Picks (Week 6): NFL DFS Advice

Welcome to RotoBaller's Daily Fantasy football DraftKings lineup picks for Week 6 of the NFL season. In this article, I, Jason Bales, will be taking you, the reader, through the best DraftKings DFS plays of the week for this upcoming Sunday.

These DraftKings lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 6. Good luck with your DraftKings DFS lineups!

Editor's Note: If you like DraftKings, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

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DraftKings Quarterbacks - Week 6 DFS Picks

Cam Newton (at NO, $8,100)

Cam Newton is recovering from a concussion, but it looks like he will be set to start for the Carolina Panthers this week against the New Orleans Saints. At home, Drew Brees is one of the best quarterbacks in the league, and the Panthers have been slipping since the beginning of the season. If they want to salvage their season, this is very close to a must win game. The Saints are going to score early and often. Newton is going to have to matchup them. The Saints' pass defense is horrendous, so the Panthers should not have too many issues finding open wide receivers, or tight ends. Newton has a rushing touchdown in two of his last four games, so fire him up due to his consistency and upside, in both 50/50 contests and tournaments.

 

DraftKings Running Backs - Week 6 DFS Picks

LeSean McCoy (vs SF, $6,900)

LeSean McCoy is one of the best running backs in the league right now. He has over 20 fantasy points in three straight games now, and this week, he gets a great matchup against the San Francisco 49ers and Chip Kelly's lightning speed offense. McCoy should have more carries and targets than he usually gets, and he has been producing with limited numbers. The Buffalo Bills are likely going to win this game, which means that McCoy will see a lot of carries in the fourth quarter. His price tag is very reasonable, and he has the upside of Le'Veon Bell and DeMarco Murray.

Carlos Hyde (at BUF, $5,100)

Carlos Hyde should not be used in the same lineup as LeSean McCoy, as both running backs are not likely going to see 20 plus carries, but he does make for a great roster move in tournaments. His upside is very high, as he has over 20 fantasy points in two of his last three starts. Against the Seattle Seahawks, a very tough rush defense, he posted 28.5 fantasy points on 21 carries. If he continues to get worked into the passing attack for the 49ers, he is going to be a semi-elite level running back within the next couple of weeks. His price tag is bound to come up at some point, so roster him while he is cheap.

 

DraftKings Wide Receivers - Week 6 DFS Picks

A.J. Green (at NE, $8,600)

A.J. Green has been fantastic so far this season with 36 receptions, 518 receiving yards, and two touchdowns. If he starts to find the end zone a little bit more frequently, he will quickly turn into a top five wide out. Two games ago, he posted over 35 fantasy points on 12 targets and 10 receptions. Unfortunately, he only does that every so often. In his last five starts, he has over 35 fantasy points twice. That upside is as high as Antonio Brown and Julio Jones, but his price tag is lower. The New England Patriots are going to score. The Bengals will be playing from behind, which should bode well for Green. After his poor performance last week, they should be attempting to get him involved in the game plan a little bit more often.

Jeremy Maclin (at OAK, $6,300)

According to Vegas, the Kansas City Chiefs are going to walk into Oakland and beat the Raiders. That is very surprising, but Vegas tends to know more than anyone else. Jeremy Maclin has been a very consistent fantasy option at the wide receiver position, so using him in 50/50 contests is the correct move. However, this week, he can also be used in tournaments. The Chiefs are going to have to score to beat the Raiders, and Maclin is their go-to target. He has over 10 fantasy points in three of his last four starts, and he only found the end zone once this season. Over 20 fantasy points is definitely possible, if he sniffs out the goal line early.

 

DraftKings Tight Ends - Week 6 DFS Picks

Coby Fleener (vs CAR, $3,500)

Coby Fleener is a very high-upside tight end option for tournaments this week against the Carolina Panthers. The Panthers are not good defensively against the tight end position, and Fleener recently posted over 25 fantasy points against the Atlanta Falcons. As previously mentioned, Drew Brees is outstanding at home, which increases Fleener's upside. He is starting to see more targets, and if the Saints are winning the game, he should see even more targets. The Saints tend to check down before running the ball. It is just how their offense works. Use Fleener in tournaments, but his consistency has not been there. As a side note, Vernon Davis (with Jordan Reed out of the Redskins' lineup) makes for a fantastic low-priced tight end option.

 




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REAL-TIME FANTASY NEWS

Sam Bennett

Exits Early Monday
Isaiah Hartenstein

Uncertain for Tuesday
Chet Holmgren

Questionable With Back Issue Tuesday
Norman Powell

in Danger of Missing Third Consecutive Game
Tyler Herro

Misses 11th Straight Game
Michael Porter Jr.

Available Against Lakers
Jalen Green

Iffy for Tuesday Night
Devin Booker

Won't Play Tuesday
Deni Avdija

Doubtful Tuesday
Hagen Smith

to Compete for Early Promotion to Triple-A?
Parker Messick

a Name to Watch in Spring Training
Yohandy Morales

in the Mix for Starting First Base Role
Harry Ford

to Compete for Starting Job?
Moisés Ballesteros

Moises Ballesteros Will See Time as a Catcher in Camp
Kevin Alcántara

Kevin Alcantara to Compete for Spot on Opening Day Roster
Kyle Tucker

Offers Outstanding Consistency at the Plate
Max Fried

Brings Continued Stability to Yankees' Rotation
Will Smith

Remains a Top Catcher in Elite Dodgers Lineup
Taylor Ward

Bat Should Play in Baltimore
Robbie Ray

Looking to Build Off Healthy Season
Andrés Muñoz

Andres Munoz a Top-Five Fantasy Closer After Another Dominant Season
Ronald Acuña Jr.

The Reward is Worth the Risk With Ronald Acuna Jr.
Joel Embiid

Officially Active on Monday
Onyeka Okongwu

Not Ready to Return on Tuesday Evening
Kevin Durant

Rockets Hoping Kevin Durant Can Return After Missing One Game
Kristaps Porzingis

Might Return on Tuesday
Emerson Hancock

to Enter Spring Training as a Starter
Vinny Nittoli

Red Sox Agree to Minor-League Deal With Vinny Nittoli
Valente Bellozo

Signs Minor-League Deal With Rockies
Luke Raley

Should Start Regularly Against Right-Handed Pitchers
Victor Robles

Appears Headed for Short-Sided Platoon Role
Shai Gilgeous-Alexander

Considered Questionable for Tuesday
Colton Ledbetter

Traded From Rays to Cardinals
Tai Peete

Cardinals Acquire Tai Peete in Three-Team Deal on Monday
St. Louis Cardinals

Cardinals Land Pitching Prospect Jurrangelo Cijntje
P.J. Washington

Sidelined for Tuesday
Julius Randle

Available Against Grizzlies
Anthony Edwards

Cleared for Action Versus Memphis
Alexandre Sarr

Active for Tuesday
Josh Giddey

Out Again on Tuesday Evening
Brad Marchand

Anton Lundell Remain Out Monday
Morgan Rielly

Out Through Olympic Break
Jusuf Nurkić

Jusuf Nurkic Resting Versus Indiana
Stephen Curry

Ruled Out for Tuesday's Matchup With Sixers
Keyonte George

Remains Out on Tuesday
Jonathan Drouin

Available Against Capitals
Logan Thompson

Expected to Return Thursday
Matthew Stafford

Doesn't Need Offseason Back Surgery
Matt Roy

Rejoins Capitals Lineup Monday
Devon Toews

Back for Avalanche Monday
Martin Necas

Remains Out Monday
Jake Neighbours

Available Monday
CFB

Joey Aguilar Files New Lawsuit Against NCAA Seeking Sixth Year of Eligibility
Davante Adams

Expected to Return to Rams in 2026
Los Angeles Rams

Rams Sign Sean McVay, Les Snead to Contract Extensions
Diego Lopes

Outclassed At UFC 325
Alexander Volkanovski

Dominates Diego Lopes
Dan Hooker

Stopped In The Second Round
Benoît Saint Denis

Benoit Saint Denis Extends His Win Streak
Rafael Fiziev

Suffers Second-Round TKO Loss
MMA

Maurício Ruffy Gets Back In The Win Column
Morgan Geekie

Extends Point Streak to Seven Games With Big Performance
Nikita Kucherov

Tallies Four Points in Stadium Series Win
Chris Kreider

Pots Two Goals in Sunday's Win
Brandon Bussi

Makes History With Another Win
Shayne Gostisbehere

Sets Up Two Goals Sunday
Mikey Anderson

Hurt Versus Hurricanes
Anthony Cirelli

Fails to Finish Stadium Series Matchup
San Francisco 49ers

49ers Set to Name Raheem Morris Their Defensive Coordinator
Las Vegas Raiders

Raiders Close to Naming Klint Kubiak the Next Head Coach
Arizona Cardinals

Cardinals Finalizing Deal to Make Mike LaFleur the Next Head Coach
CFB

Gus Malzahn Retiring from Coaching
Breece Hall

Jets Want to Re-Sign Breece Hall, Could Use Franchise Tag
Troy Terry

Ready to Return Sunday
Victor Hedman

Set to Return Sunday
Connor McMichael

Out Week-to-Week
Kris Letang

Out for Four Weeks
Nico Hischier

a Game-Time Call Saturday
Diego Lopes

An Underdog At UFC 325
Alexander Volkanovski

Set For UFC 325 Main Event
Benoît Saint Denis

Benoit Saint Denis Looks To Extend His Win Streak
Dan Hooker

Set For UFC 325 Co-Main Event
Mauricio Ruffy

Looks To Get Back In The Win Column
Rafael Fiziev

Returns At UFC 325
CFB

Texas Lands Wake Forest Transfer Sterling Berkhalter
Kirk Cousins

Falcons Expected to Release Kirk Cousins
Chase Brown

Working on Extension With Bengals
Michael Penix Jr.

Hopes to be Ready for Week 1
Dalton Kincaid

Doesn't Need Offseason Surgery
Josh Allen

Undergoes Foot Surgery
Josh Allen

on Crutches, Wearing Walking Boot
CFB

Michigan RB Bryson Kuzdzal Withdrawing from Transfer Portal
Bo Nix

Expected to Resume Training in 4-6 Weeks
Michael Penix Jr.

Thinks he'll be Ready by April
Cleveland Browns

Browns Hiring Todd Monken as Next Head Coach
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