Wide Receiver Matchups to Target For Week 17 (2025) - Ja'Marr Chase, Chris Olave, Jakobi Meyers, Stefon Diggs, Tre Tucker

Kyle's favorite WR vs. CB matchups to exploit for Week 17 of 2025 - DFS wide receivers to target on DraftKings and FanDuel. These WR/CB matchups are GPP and cash game opportunities.

Welcome to the Wide Receiver Matchups to Target column for Week 17 of the 2025 NFL season. We're nearing the end of the season, so we have all the data in the world at our disposal. We'll use individual performance, matchup grades, pace of play, and implied totals to pinpoint the best WRs to target in daily fantasy lineups. Week 16 didn't quite go as planned, as Nico Collins, Justin Jefferson, and Jakobi Meyers didn't come close to reaching 3x their salary. Ja'Marr Chase had a big game, but he finished just short of 3x with 22.9 DK points. 

This week, we'll break down the top five WR/CB matchups using Pro Football Focus (PFF) grades, along with key usage metrics that indicate which players can realistically hit three times their DraftKings salary. This is meant to serve as a guide for both cash games and GPPs -- these guys are in position to smash regardless of the contest type you're playing in.

Be sure to jump into our RotoBaller Discord! We have so many different channels devoted to whatever you're playing in fantasy football. We also have lots of great NFL DFS articles and NFL DFS tools to help you win MORE this season! Below are my top five WR vs. CB matchups for this week’s DFS main slate. Use these insights to fine-tune season-long lineups, player props, and DFS builds. Let’s get to it!

Ja'Marr Chase, Cincinnati Bengals

• $8.3K on DraftKings, $9.4K on FanDuel
• Vs. Darren Hall, Will Johnson, Denzel Burke (Arizona Cardinals)

We're rolling with Chase as the top high-dollar wide receiver to target on the Week 17 main slate. The All-Pro is having another monster season, producing at least 20 DK points in eight of his last 10 games while ranking second on the slate with a 20.5 DK PPG average. He currently ranks #1 in targets (166), #3 in target share (33%), #4 in red zone targets (19), #2 in receptions (110), #4 in receiving yards (1,256), and #2 in yards after catch (549) despite playing over half the season without Joe Burrow at QB.

“I think the biggest thing on the list is to score another touchdown. I think I’ve been overdue since Week 7.” Ja’Marr Chase on his goals for last two weeks. Hasn’t scored TD since Oct 16 vs. Pittsburgh pic.twitter.com/a4XBK5hj8b

— Mike Petraglia (@Trags) December 26, 2025

Burrow is back under center, and Chase is still putting up numbers, so we don't have any reason not to get exposure to him in DFS lineups against a leaky Arizona defense. The Cardinals rank 29th in PFF's defense grade, 22nd in PFF's coverage grade, and 25th in defensive EPA this season. They've also allowed 242.3 passing yards per game over their last three contests, the ninth-highest mark in the league.

The individual matchups against Will Johnson (32nd of 110 CBs) and Denzel Burke (26th of 110 CBs) don't look great on paper, but this is a defense that has really struggled down the stretch, as they rank 27th in pass DVOA since Week 12. The Bengals hold the highest implied total on the slate at 30.5 points - get Chase into your lineups.

Chris Olave, New Orleans Saints

• $7.2K on DraftKings, $8.1K on FanDuel
• Vs. Jalyn Armour-Davis, Darrell Baker Jr., Marcus Harris (Tennessee Titans)

Olave is the third-highest-priced wide receiver on the DraftKings main slate, and he comes in as the fifth-highest-priced receiver on FanDuel. There's undoubtedly some sticker-shock going on as he was priced around $5,000 on DraftKings through Week 7, but it's completely warranted as he put up 20.5 DK points in Week 15 and a slate-breaking 39.8 DK points in Week 16. Last week's 10/148/2 stat line came against the Jets, who are one of the more exploitable secondaries in the league. He gets an even better matchup this week against the Titans.

Chris Olave got some of the best hands in the league 👀 pic.twitter.com/qWVqEOHV7T

— Football’s Greatest Moments (@FBGreatMoments) December 24, 2025

Tennessee rolls out Jalyn Armour-Davis (97th of 110 CBs), Darrell Baker Jr. (80th of 110 CBs), and Marcus Harris (30th of 110 CBs) at cornerback. Harris will be the primary cover man, but Olave will see plenty of Armour-Davis as well, a player who has allowed a 77% catch rate and 14.4 yards per reception this season. The Titans allow the 12th-most FPPG vs. WRs while ranking 27th in pass DVOA, 31st in pass DVOA vs. WR1s, and 28th in defensive EPA this season.

They've allowed the third-most yards per game against WR1s and the eighth-most receiving yards to receivers, so the metrics are all pointing to this being an exploitable matchup. The Saints hold a meager 21-point implied team total in a road game with a low 39.5-point implied total, but Tyler Shough has no one else to throw to. Olave will continue to be peppered with targets and will have an excellent chance at crushing his salary again in this terrific matchup.

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Jakobi Meyers, Jacksonville Jaguars

• $5.3K on DraftKings, $6.8K on FanDuel
• Vs. Johnathan Edwards, Mekhi Blackmon, Kenny Moore II (Indianapolis Colts)

Meyers has been a regular in this article, and while it didn't pay off last week, he has been the clear WR1 for the surprising Jaguars since being acquired. Since Week 10, Meyers leads the team in targets (46), target rate (26%), receptions (31), and receiving yards (400). He has been held under 50 receiving yards in four of his seven games as a Jaguar, but it doesn't feel likely that he'll be held in check against arguably the worst cornerback room in the NFL this week.

Johnathan Edwards (109th of 110 CBs), Mekhi Blackmon (103rd of 110 CBs), and Kenny Moore II (62nd of 110 CBs) have all struggled mightily this season. Edwards and Blackmon can make an argument as two of the worst corners in the league, and those are the two that will be tasked with defending Meyers the most. The recent and season-long numbers back up the unit's poor play as the Colts have fallen off the metaphorical cliff to finish out the season.

Indianapolis has allowed the second-most passing yards per game (251 yards), the most receptions, and the fourth-most receiving yards to wide receivers. Over their last five games, they've allowed the third-most passing yards per game (269 yards) while ranking 23rd in pass DVOA, 29th in pass DVOA vs. WR1s, and 31st in defensive EPA. They can't stop anyone, as evidenced by the Jaguars' high 27-point implied team total. Get Meyers into your lineups while he's still priced in the mid-range.

Stefon Diggs, New England Patriots

• $5.8K on DraftKings, $6.5K on FanDuel (DraftKings Preferred)
• Vs. Jordan Clark, Qwan'tez Stiggers, Brandon Stephens (New York Jets)

Stefon Diggs makes an appearance! The veteran receiver is fresh off a 25.8 DK point outing where he caught 9-of-10 targets for 138 yards against a vulnerable Ravens' defense. He has contract incentives to reach, and he'll have a great chance to secure them as he'll be going up against an inexperienced and overmatched Jets secondary. He projects to see the most snaps against Jordan Clark (unranked), but Qwan'tez Stiggers (unranked) and Brandon Stephens (38th of 110 CBs) are also in the mix.

The metrics are not pretty for the Jets. They rank 32nd in pass DVOA, 29th in pass DVOA vs. WR1s, and 29th in defensive EPA. Since Week 12, they rank 31st in pass DVOA and 30th in defensive EPA. They've also allowed the sixth-most passing yards over the last three weeks. Vegas expects the Patriots to score a lot as they have them with a 28-point implied team total, so we could easily see Diggs put up another ceiling game in this favorable matchup.

Tre Tucker, Las Vegas Raiders

• $3.8K on DraftKings, $5.4K on FanDuel
• Vs. Paulson Adebo, Cor'Dale Flott (New York Giants)

Tucker is priced in "bargain-bin" territory over on DraftKings, and he's someone we can take some shots on as the de facto WR1 against a poor Giants defense. None of his numbers jump off the page, but he put up a usable 9.4 DK points in a brutal matchup against the Texans last week, snagging 4-of-5 targets for 43 yards while adding 11 yards on two carries.

The Giants allow the sixth-most fantasy points per game to WRs while ranking 26th in pass DVOA and 26th in pass DVOA vs. WR1s this season. Paulson Adebo (90th of 110 CBs) will be one of his primary defenders, and he has been awful lately with a 74% catch rate and 12 yards per reception allowed over his last five games. Geno Smith doesn't inspire much confidence in the passing game, but this matchup is favorable enough for even a washed, overpaid veteran to find some success. Tucker looks excellent as a value-saving option at WR this week.

Thanks for reading, and good luck with your DFS contests!

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