👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

Thanksgiving Day DraftKings NFL DFS Picks (2022): Break The Slate

Dak Prescott - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Joe Nicely's DraftKings NFL DFS picks and lineup sleepers for the Thanksgiving Day (November 2022) Main Slate. His top daily fantasy football lineups to target for DraftKings DFS contests.

Hello RotoBallers and welcome to a very special Thanksgiving Day edition of Break The Slate! I appreciate you joining me in our season-long quest to find the best plays at each position for every DraftKings Main Slate.

Like turkey, dressing, and in-laws, the NFL's Thanksgiving Day slate has turned into an annual tradition. This year's football feast offers us three enticing matchups to choose from on the DraftKings holiday slate! With only three games to work with, it always pays to be a bit contrarian in lineup construction, which is reflected in a couple of this article's selections.

These DraftKings lineup recommendations are based on matchups, projected DK points and ownership, overall upside/talent levels, and opportunity, as well as factors such as Vegas odds, home-field advantage, and more. There are quite a few great plays available on DK for the Thanksgiving Day slate. Also, be sure to also check out our weekly FanDuel DFS lineup picks and lots of other great NFL DFS articles and NFL DFS tools to help you win big! Good luck with your DraftKings DFS lineups – let's Break The Slate together!

Featured Promo! Save 30% on any Premium Pass using discount code NEW. Win more with our DFS, Betting and Season-Long Pass, get expert tools and advice from proven winners! GAIN ACCESS

 

DraftKings Quarterbacks - Thanksgiving Day DFS Picks

Josh Allen - BUF @ DET ($8,000)

Buffalo’s gunslinger comes into the Thanksgiving slate off his worst performance of the season against the Cleveland Browns, a game in which he managed just 12.6 DK points. 

Due to the weather in New York, the Bills played the Browns at Ford Field, so Allen and the boys will be chillin’ in Motown all week. We can expect a bounce back in this trip to Ford, as the Lions present the overall fantasy QB2 with a matchup that should provide a true Thanksgiving Day feast.

While Dan Campbell’s bunch has shown some heart and #Grit in recent weeks, this is a defense that still has very real limitations. Detroit ranks dead last in the NFL in DK points allowed to the QB position and grades out 24th in Pass Defense DVOA this season. Despite the fact that he didn’t quite look like himself last week, Allen should take full advantage of the Lions’ weaknesses in this one. 

Dak Prescott NYG @ DAL ($6,200)

The New York Giants have been a nice story under first-year HC Brian Daboll, but a loss to the Detroit Lions last week illustrates that there’s a bit of smoke and mirrors at play with Big Blue.

The G-Men’s last four games have been against: Detroit, Houston, Seattle, and Jacksonville. Despite that soft stretch, New York still ranks just 24th in the league in Total Defense DVOA and is tied for the fewest INTs in the NFL with only two. 

Since returning from an extended injury absence, Dak Prescott has the ‘Boys' offense rolling and he’s now scored 20 or more DK points in three straight. Dallas comes in off a 40-3 destruction of Minnesota and I expect Dak to pick apart the Giants’ benign secondary in this one.

 

DraftKings Running Backs - Thanksgiving Day DFS Picks

Dalvin Cook - NE @ MIN ($7,400)

On a short slate such as this one, we must be willing to go against the grain in some spots. Dalvin Cook represents a nice way to grab some ownership leverage with a talented player.

Many will shy away from Cook here due to the difficult matchup against a New England Patriots unit that has a well-deserved reputation for being tough against the run.

Although the Pats grade out 13th in Rush Defense DVOA (good, but not great), I'm willing to bet on Cook's talent over the matchup. As of this writing, I have the Vikes' back projected as the fifth-highest-owned RB on the Thanksgiving slate. Those are numbers I'll take for a player that's explosive and averaging 19.5 touches per game over Minnesota's last five.

Jamaal Williams - BUF @ DET ($5,900) 

It’s fair to label Jamaal Williams a “touchdown-dependant RB”, but the thing is…he keeps scoring touchdowns every week. While the threat of D’Andre Swift is always looming, Dan Campbell and this Lions staff have shown that they simply love and trust Williams.

He’s averaging 15.9 carries per game on the season and 19 totes per game over their last three, despite Swift’s recent return to the lineup. Williams has now posted 20 or more DK points on four occasions this season.

 

Want more NFL DFS tools and content? Our NFL Premium package includes our DFS Cheat Sheets, Research Station, Lineup Optimizer, access to our Premium Discord Chatrooms where members can chat with our NFL analysts, and so much more. Check out this big win from RotoBaller's RealTalkRaph using our Premium tools - join in on the winning!

 

DraftKings Wide Receivers - Thanksgiving Day DFS Picks

Amon-Ra St. Brown - BUF @ DET ($6,600)

The clear alpha of a receiving corps that’s both injury-depleted and talent deficient, The Sun God is a crisp route-runner and target monster. Finally fully healthy, St. Brown has garnered a ridiculous 37.8% team target share over Detroit’s last three, a mark that trails just Davante Adams since Week 8.

So, we can expect Jared Goff to look St. Brown’s way early and often this Thursday, and we can even bump his already-significant target projection due to the expected game environment against the explosive Bills. 

The matchup is, admittedly, a tough one. However, this Bills secondary has been banged up and not quite as formidable as we’ve seen in the past. Buffalo ranks 22nd in the NFL in both receiving yards (1,616) and receiving TDs (10) allowed to the WR position this year.

Isaiah Hodgins - NYG @ DAL ($3,000)

The Giants’ receiving corps has been a revolving door of ineffectiveness this season, as New York has struggled to keep wideouts on the field and productive. This led the G-Men to claim Isaiah Hodgins off waivers from the Buffalo Bills at the beginning of November. 

Former Bills’ OC and current Giants’ HC Brian Daboll is very familiar with Hodgins from his time in Buffalo and he’s wasted no time inserting him into Big Blue’s rotation. The 2020 sixth-round pick has responded by catching all five of his targets for 70 yards in his two games with NY.

His role could increase even more on Thanksgiving, as Giants’ rookie Wan’Dale Robinson was seen on crutches after NY’s Week 11 loss to Detroit and has reportedly torn his ACL. With Robinson out of the lineup against the Cowboys - and DFS players immediately turning to Darius Slayton - Hodgins should be firmly on our GPP radar as a salary-saving pivot for this unique three-game Turkey Day slate.

 

DraftKings Tight Ends - Thanksgiving Day DFS Picks

Dalton Schultz - NYG @ DAL ($3,800)

Due to Dak Prescott’s return to the lineup coinciding with his own recovery from injury, Dalton Schultz has been a favorite in this article in recent weeks. I’m sticking with the talented Cowboys TE on this Turkey Day slate due to his significant role in this Dallas passing attack and his terrific matchup against a Giants squad that’s struggled to slow down opposing tight ends.

The G-Men grade out 31st in the NFL in DVOA defense vs. TEs. New York is allowing a massive 73.5% successful catch rate to the TE position, as well as just under 8.5 yards per target.

Schultz’s sizable role in this talented Dallas passing attack should equip him to take full advantage of this favorable matchup. Since Prescott returned to the lineup in Week 7, Schultz has averaged 6.3 targets per game, the fifth-most in the NFL at the position in that timeframe.

Dawson Knox - BUF @ DET ($3,500)

After a sluggish start to the year - something we can only assume is associated with the tragic death of his little brother just before the start of the season - Knox has slowly been earning targets again.

The big Bills TE has now been targeted 17 times over Buffalo’s last three, converting those looks for 14 catches and 152 receiving yards. 

That positive momentum should continue against Detroit this week. The Lions are relinquishing 8.64 yards per target to opposing TEs and have allowed the second-most TDs in the NFL (7) to the position this season



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis

POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Tony Pollard

Remains the Lead Back for Now
David Montgomery

Is David Montgomery Really the Bell Cow in Houston?
Chris Godwin Jr.

a Low-End WR2 After Teammate's Departure?
LeQuint Allen Jr.

to Get More Involved in Year 2?
Isaiah Davis

Faces Improbable Path to Fantasy Relevance
Michael Carter

Signing with the Titans
Puka Nacua

Checks Into Rehab Facility
Jock Landale

Leaves Game with Ankle Injury
Paul George

Explodes for 39 Points in Win Over Wizards
Jerami Grant

Still Out Thursday
Trey Murphy III

Could Miss Fourth Straight Game
Marcus Smart

to Miss Sixth Straight Game
Gary Trent Jr.

Exits Early with Hip Injury
Mark Williams

Could Return Against Hornets
Aaron Gordon

Returns Against Utah
Gary Payton II

Out Wednesday
Gui Santos

Ruled Out Against San Antonio
Bobby Portis

Kyle Kuzma Ruled Out Wednesday
Ryan Rollins

Won't Suit up on Wednesday
Obi Toppin

Good to Go Against Chicago
Myles Turner

Won't Play on Wednesday
Pascal Siakam

to Play on Wednesday
Scottie Barnes

is Available on Wednesday
Brandon Ingram

is Absent on Wednesday
Immanuel Quickley

to Miss Sixth Straight Game
Jalen Brunson

is Ruled Out on Wednesday
Josh Giddey

Sidelined on Wednesday
Anthony Edwards

Considered Questionable for Thursday
Brandon Hagel

Likely Out on Thursday
Damon Severson

Not Expected to Return During Regular Season
Igor Chernyshov

a Game-Time Call Wednesday
Radko Gudas

Out Wednesday
Cutter Gauthier

Questionable for Rest of the Week
Evander Kane

Unavailable Wednesday
Cale Makar

to Miss "Some Time"
Konnor Griffin

Pirates in "Deep" Negotiations for Long-Term Contract
Carlos Estévez

Royals Place Carlos Estevez on 15-Day Injured List
CFB

Gunner Stockton Looking "Great" After Offseason Injury
CFB

Sam Leavitt Showing "Encouraging Signs" at LSU Practice
Hendon Hooker

Signs with the Titans
Kaleb Johnson

Given a Clean Slate with New Coaching Staff
DK Metcalf

Dynasty Outlook Murky with Quarterback Uncertainty?
Trey McBride

Is Trey McBride the TE1 in Dynasty Fantasy Football?
Mark Andrews

Faces Less Competition in Tight End Room
Wan'Dale Robinson

the Clear No. 1 Target in Tennessee?
Brock Purdy

Supporting Cast Gets an Upgrade for 2026
Jalen McMillan

Headed for a Bigger Role in 2026
Ashton Jeanty

Poised to Break Out with Improved Offense and Protection?
Justin Jefferson

Poised to Re-Emerge as an Elite Dynasty Wide Receiver in 2026
J.J. McCarthy

Dynasty Value is Fading Heading into 2026
NFL

Brenen Thompson May Struggle to Consistently Earn Targets in the NFL
Drake Maye

Can Drake Maye Overcome Questionable Supporting Cast in New England?
Garrett Wilson

Will Garrett Wilson Have a More Stable Environment Around Him in New York Going Forward?
J.J. Spaun

Needs the Putter to Cooperate in San Antonio
Thorbjorn Olesen

Trending Up in San Antonio
Denny McCarthy

Carrying Momentum into San Antonio
Matt Grzelcyk

Unavailable for Reminder of Season
Artyom Levshunov

Ruled Out for Rest of Season
Mathieu Olivier

to Miss Couple of Weeks
Evan Rodrigues

to Have Season-Ending Surgery
Sam Reinhart

Won't Return This Season
Carter Yakemchuk

Injured in Tuesday's Loss
Aaron Ekblad

Hand Injury "Doesn't Look Good"
Jose Fernandez

Launches Two Home Runs in Historic MLB Debut
Chase DeLauter

Exits Tuesday's Game with Foot Injury, X-Rays Come Back Negative
Chris Kirk

Has Course History on His Side in San Antonio
Billy Horschel

a Volatile Option at the Valero Texas Open
Joe Highsmith

Still Searching for Form in San Antonio
Christiaan Bezuidenhout

Looks to Find Form at the Valero Texas Open
Seiya Suzuki

to Begin a Rehab Assignment Soon
Simon Holmstrom

Misses Tuesday's Action
Alexandre Carrier

Out 2-4 Weeks With Upper-Body Injury
Jordan Spieth

a Horse for Course History at TPC San Antonio
Mason Lohrei

Misses Second Consecutive Game Tuesday
Tyler Myers

Unavailable Against Bruins
Robert MacIntyre

Has One Flaw to Overcome at Valero Texas Open to be a Must-Play
Michael Bunting

to Sit Out Tuesday's Game
Maverick McNealy

In Exceptional Form This Season
Michael Thorbjornsen

Playing Well But Still Searching For A Win
Hideki Matsuyama

Playing Well Heading to the Valero Texas Open
Si Woo Kim

Heads to Valero Texas Open For Final Tune-Up Before Masters
Nikita Kucherov

a Game-Time Decision Tuesday
Evgeni Malkin

Ready for Action Tuesday
Cody Ponce

Diagnosed With ACL Sprain, to Miss "Significant Time"
Collin Morikawa

Withdraws From Valero Texas Open
PGA

Stephan Jaegar Still Looking For Consistency at Valero Texas Open
Nicolai Hojgaard

is Red-Hot Coming to TPC San Antonio
Tony Finau

a Risky Proposition at Valero Texas Open
Ludvig Aberg

Looks to Shake Off Collapse at Valero Texas Open
Jacob deGrom

Cleared for Season Debut on Tuesday
Colt Emerson

Signs an Eight-Year Extension with Mariners
Patrick Rodgers

Needs to Make More Birdies in San Antonio
Sepp Straka

Seeks Opportunity in San Antonio This Weekend
Nick Taylor

Could Again Struggle at the Valero Texas Open
Jose Altuve

Tallies Four Hits, Two Homers in Big Night
Miguel Vargas

Hits Grand Slam, Drives in Six in Win Over Miami
Tanner Bibee

to Start on Tuesday Against Dodgers
Chase Elliott

Takes Advantage of Pit Strategies for Second Career Martinsville Win
Denny Hamlin

Dominates but Finishes Second at Martinsville
Joey Logano

Bounces Back with Third-Place Finish at Martinsville
Ty Gibbs

Gains his Fourth Top-Five Finish of the Season at Martinsville
William Byron

Scores Another Top-Five Finish at Martinsville
Joe Pyfer

Extends His Winning Streak
Israel Adesanya

Loses Fourth Consecutive Fight
Maycee Barber

Suffers Her First Knockout Loss
Alexa Grasso

Scores Highlight-Reel Knockout
Niko Price

Retires After UFC Seattle Loss
Michael Chiesa

Victorious In His Retirement Fight
Julian Erosa

Suffers First-Round Knockout Loss
Lerryan Douglas

Scores First-Round Knockout Win In His UFC Debut
Alex Bregman

Clobbers First Two Homers in Sunday's Loss at Wrigley
Yandy Díaz

Yandy Diaz Records Five Hits, Drives in Four in Win Over Cardinals
Kyle Larson

Is Likely to Pay Off for DFS at Martinsville
Christopher Bell

Could Have Another Top-10 Performance At Martinsville
William Byron

Is A Threat to Win Again at Martinsville
Chase Elliott

is A Solid DFS Option for Martinsville Lineups
Chase Briscoe

has Plenty of Upside for DFS Lineups at Martinsville
Carlos Estévez

Carlos Estevez Unlikely to See High-Leverage Opportunities in Near Future
Jacob deGrom

Feels "Much Better," Hopeful he Can Start This Week
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Martinsville?
Ryan Preece

Is A Solid DFS Option for Martinsville Lineups
Josh Berry

Could Josh Berry Pay Off for Tournament DFS Lineups At Martinsville?
Carson Hocevar

May be Too Inconsistent to Start in Martinsville DFS Lineups
Austin Cindric

Is Austin Cindric Worth Rostering for DFS At Martinsville?
Denny Hamlin

the Favorite to Win at Martinsville
Ryan Blaney

Should Contend at Martinsville
Tyler Reddick

Should Come Back Down to Earth at Martinsville
Joey Logano

Will Be Strong at Martinsville
NASCAR

Bubba Wallace Looking to Rebound at Martinsville
Shane Van Gisbergen

Shane van Gisbergen Showing Progress, Qualifies Fifth at Martinsville
Dylan Cease

Fans 12 in Blue Jays Debut on Saturday
Andrew Vaughn

Needs Hand Surgery, Expected to be Out 4-6 Weeks
Jacob deGrom

"Confident" he Will Make his Next Start
Jacob deGrom

Scratched From Saturday's Start Due to Neck Stiffness
Jeferson Quero

Brewers Calling Up Catching Prospect Jeferson Quero
Deyvison De Los Santos

Marlins Promote Deyvison De Los Santos to Major Leagues
Joe Pyfer

Set For UFC Seattle Main Event
Israel Adesanya

Returns At UFC Seattle
Maycee Barber

Looks To Extend Her Win Streak To Eight
Alexa Grasso

Looks To Get Back In The Win Column
Niko Price

In Dire Need Of Victory
Michael Chiesa

Set For Retirement Fight
Lerryan Douglas

Set For His UFC Debut
Julian Erosa

Looks To Bounce Back
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF