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Jamie's top DraftKings and FanDuel MLB DFS picks for today, Tuesday, 5/6/25. His favorite daily fantasy baseball lineup sleepers and value picks for DFS on DraftKings and FanDuel.
Knicks! Knicks! Knicks! Sorry, I know this is a baseball article, but I'm still so pumped from their win in Boston last night (for full details on my excitement, check out the RotoBaller Discord NBA channels. Anyway, to business. We have a full 12-game slate tonight in MLB, and a slew of different ways to build. Lineups will tell a huge tale about how we build.
As always, be sure to jump into the RotoBaller Discord MLB DFS channel, as our community will be discussing all the matchups, analyzing lineups, and just having fun chatting about the Great American Pastime.
This article will provide my daily fantasy baseball lineup picks for DraftKings and FanDuel on 5/6/2025, with the slate starting at 7:05 p.m. EDT. The lineup picks will showcase elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for other sports here. Monitoring injury news and today's MLB starting lineups is always essential.
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DraftKings, FanDuel Pitchers - MLB DFS Lineup Picks
Zack Wheeler, PHI ($9.7K DK/$11K FD)
It's a tough decision at the top between Paul Skenes and Zack Wheeler. Both have less-than-stellar matchups as far as K rates against, but they are still both worth their respective price tags. Ultimately, my lean is in favor of Wheeler today, as Skenes' K rate is way down to start the season.
Wheeler is rocking a 32.8% K rate for 2025, and his xFIP is over a run lower than his ERA. He has 29 Ks over his last three games, and a 17.2% swinging strike rate. He's been at least six innings in every start this season except for one, so he has the floor for cash and the ceiling for GPP.
Skenes is arguably a better value on FD, where he is cheaper, but Wheeler should not be under $10k on DK.
Chris Sale, BOS ($8.8K DK/$9.9K FD)
Like his more expensive predecessors, Chris Sale doesn't have the optimal K matchup (Cardinals are 23rd in K rate against LHP). However, Sale is still sporting a 29.7% K rate, and his 30.7 CSW is the highest-projected of the night.
Sale has been victimized by some bad luck this year, as his 4.84 ERA is a smokescreen (he has a 3.25 xFIP and 2.94 SIERA). The park factor also works in his favor, and St. Louis is 27th in barrel rate as a team over the last 10 games.
Others To Consider (Cash/GPP):
- Paul Skenes, PIT ($10K DK/$10.8K FD)
- Seth Lugo, KC ($8.7K DK/$9.2K FD)
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DraftKings, FanDuel Infielders - MLB DFS Lineup Picks
Bobby Witt Jr., KC ($5.8K DK/$4K FD)
The Royals have an IRT over five runs tonight, which should immediately make you take notice. Bobby Witt Jr. will be at the center of any run barrage as he's once again offering a nightly upside of power and speed. Sean Burke is not a pitcher to fear, as he's struck out under seven batters per nine this year with a 33.7% GB rate.
Witt is a premier hitter for KC, offering a unique mix of power and speed. He's hit amazingly in the reverse split, posting a .388 wOBA and .237 ISO against RHP since the beginning of last year. In addition to Burke, the White Sox bullpen is projected to be the second-worst this season, according to ZiPS.
Matt Olson, ATL ($4.6K DK/$3.1K FD)
The Braves are one of my favorite offenses to target against Andrew Abbott tonight. I wouldn't go nuts overloading them in cash as Abbott has the K upside to neutralize any team (10.89 K/9 so far). However, his control issues and his struggles in the reverse split make Matt Olson one of the top hitter targets.
Abbott has allowed over a 40% HHR to LHB since the beginning of last year, and Olson has a .360 wOBA and .238 ISO against same-handed pitching in that span. His price on DK is great for all formats, and his price on FD is borderline criminal for a player of his caliber.
Zach Neto, LAA ($4.3K DK/$3.3K FD)
Be honest - if I were to ask you which Angel hitter has a .430 wOBA and .241 ISO against LHP since the beginning of 2024, you'd say Mike Trout, right?
You'd be dead wrong, and the answer is Zach Neto. In addition, the Angels' shortstop has a top-5 barrel rate in MLB over the last five games, and will hit leadoff (giving him a chance at five PAs).
Eric Lauer continues to hold his own as a strikeout pitcher, hovering at right around a batter per inning over most of his career. However, his 30% GB rate and 5.09 xFIP suggest blowups should be fairly common, and Neto has hit safely in 10 straight contests.
Others To Consider (CASH/GPP):
- Ketel Marte, ARI ($5.3K DK/$3.2K FD - MUCH better value on FD)
- Austin Riley, ATL ($4.8K DK/$3.4K FD)
- Joey Bart, PIT ($3.6K DK/$2.6K FD)
DraftKings, FanDuel Outfielders - MLB DFS Lineup Picks
Juan Soto, NYM ($5K DK/$3.7K FD)
The highly scrutinized Juan Soto has started to come around for the Mets, and it's only a matter of time before he's over $6K on DK and $4K on FD. Over the past five games, Soto has four XBH and two HRs, along with a 47% HHR.
Zac Gallen is not a pitcher we usually like to target, as he's one of the stronger starters on the slate. However, he's struggled immensely with lefties to start 2025. In 19 innings, Gallen has allowed a .388 wOBA and 1.93 HR/9 to opposite-handed hitters.
Kerry Carpenter, DET ($4.6K DK/$3.8K FD)
The Tigers should be considered a top stack tonight as they're at Coors Field and the weather (right now) looks favorable for hitting. Kerry Carpenter is my favorite per-dollar play of the night for cash, and should also be a cornerstone for GPP stacks as the leadoff hitter in Coors.
Carpenter has crushed RHP since the beginning of last year to the tune of a .407 wOBA and .306 ISO, and Chase Dollander will go through some serious growing pains pitching in Colorado. Once he's out, Carpenter gets to tee off against the worst bullpen in the majors. Lock him in, even at elevated price tags.
Randal Grichuk, ARI ($2.6K DK/$2.5K FD)
Your value outfield value of the night is Randal Grichuk, who is near minimum price tags on both sites. Grichuk has dipped in the power department as his career has reached its twilight, but he can still be utilized in DFS against lefties.
Grichuk should have a top-five lineup spot tonight against David Peterson, and he's posted a .368 wOBA and .195 ISO against LHP since the beginning of last year. In that span, Peterson has a 4.66 xFIP against RHB.
Others To Consider (CASH/GPP):
- Marcell Ozuna, ATL ($4.5K DK/$3.5K FD)
- Riley Greene, DET ($4.8K DK/$3.8K FD)
- Fernando Tatis Jr., SD ($6.1K DK/$3.9K FD)
DraftKings, FanDuel MLB DFS Stacks
1. Atlanta Braves vs. Andrew Abbott
While Abbott's 29.1% K rate could shut down a stack on any given night, it's necessary to take risks in GPPs. Abbott also has a 15.2% BB rate and 4.67 xFIP, so a blowup is equally plausible. The Braves are a top offense in terms of HHR over the last 10 games, and have an IRT of 4.8 runs.
Favorite Combo: Albies, Riley, Ozuna, Olson
2. Detroit Tigers vs. Chase Dollander
The Tigers have an IRT of 5.4 runs in Coors Field tonight, which means you're stacking. Dollander is a touted prospect, but he will take his lumps pitching at home. In addition, the Rockies' bullpen is currently last in wOBA and ISO allowed since the beginning of last year. I mentioned Carpenter, but his teammates have immense upside as well.
Favorite Combo: Carpenter, McKinstry, Greene, Torkelson
3. Kansas City Royals vs. Sean Burke
I'm into the Royals tonight, as their IRT is second only to the Tigers in Coors. Burke has a 5.85 FIP, a 7.23 xERA, and has only struck out 6.82 batters per nine. The Royals are a high-octane offense when they're right, and Witt is surrounded by some cheap upside options, which gives you access to top pitching as well.
Favorite Combo: India, Witt Jr., Pasquantino, Perez
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