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Break The Slate: NFL DFS DraftKings Lineup Picks - Week 17

Joe Nicely's DraftKings NFL DFS picks and lineup sleepers for Week 17. His top daily fantasy football recommendations to target for DraftKings DFS contests.

Hi RotoBallers and thanks for joining me for Week 17! This is annually one of the most interesting weeks of the season due to each team's varying motivations and positions in the playoff picture. This year is no different, as we will see a couple of teams resting or gearing back their starters because they've either locked playoff seeding or are out of the postseason picture entirely. Let's dive into the madness!

These DraftKings lineup recommendations are based on matchups, projected ownership, overall upside/talent levels, opportunity, and other factors such as Vegas odds, home-field advantage, and more. There are some great plays available, so read on to find out which players are the best for Week 17.

Good luck with your DraftKings DFS lineups, let's Break The Slate together!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 17 Picks

Jameis Winston - ATL @ TB ($6,600)

Baltimore's Lamar Jackson won't play this week, which makes the QB spot a wide-open proposition. While some teams have cloudy motivations this week, the Bucs are clearly trying to finish the season with a .500 record in order to carry some positives into the offseason after their first year under HC Bruce Arians. We've continuously touched on the fact that Jameis Winston might not be a good "real life" QB, but he is a DFS All-Star. I'm willing to live with his bone-headed mistakes in exchange for his fantasy upside and Jameis should once again be able to produce a strong score against a Falcons Defense that ranks 24th in the league in DK points allowed to opposing QBs.

Carson Wentz - PHI @ NYG ($6,100)

Motivation means a lot this late in the season and the Eagles head into Week 17 with tons of it. Philly has a "win and in" scenario in this matchup against the New York Giants, which piques my interest in Eagles QB Carson Wentz. After looking sluggish for the better part of the year, Wentz has stepped up his play over the past month. Wentz has went over 300 yards passing in three of Philly's last four games while throwing for nine TDs since Week 12. He gets a juicy matchup against a Giants secondary that is allowing the third-most yards per attempt in the NFL to the QB position and his reasonable $6.1k price tag makes him my favorite play in the mid-tier salary range.

Case Keenum - WAS @ DAL ($4,500)

I expected to have RG3 as this week's "salary saver" option, but with the Ravens in a tough matchup against a Steelers team that will be playing all out, I think a pivot to Washington's Case Keenum could pay dividends in GPPs. Rookie QB Dwayne Haskins will sit this one out, which paves the way for the well-traveled Keenum - who I consider to actually be a fantasy upgrade for this offense at the moment. Keenum is a bargain around the industry and has posted some useful DFS scores in limited action this season. He completed 16 of 22 passes for 158 yards and a TD, as well as ran for a score in relief of Haskins in the second half last week. The matchup against the Dallas Cowboys isn't great, but I certainly expect him to return value on his $4.5k price tag.

*SATURDAY UPDATE: Jameis Winston is listed as 'Questionable', but is fully expected to play. The setup for Wentz makes him my favorite play at what's a fairly "Meh" QB position this week. Washington's Terry McLaurin has been ruled out which does certainly put a dent in Case Keenum's upside, though he still remains a great way to save salary.

 

DraftKings DFS Running Backs - Week 17 Picks

Aaron Jones - GB @ DET ($8,200)

I really don't like recommending Aaron Jones...especially at this type of price. I know that sounds like a strange thing to say since I'm listing him here, but I feel like I should put an asterisk beside his name. Jones has as much upside as any RB on the slate - as evidenced by 30-plus DK point performances in two of Green Bay's last three - but he is also more likely to "completely bust" than any RB in this price range due to his frustrating lack of consistent usage in this Packers offense. Even with spotty volume, Jones has more TDs than any player in the NFL this year, which obviously makes him a very viable tournament target. Throw in the fact that Green Bay is playing for a first-round bye this week, will square off against a Lions Defense that is one of the worst units in the league, and has labeled Jones' backfield mate Jamaal Williams with a 'Questionable' tag...and it feels as though Jones has more paths than usual to a big workload, which gives me the confidence to list him here this week.

Ezekiel Elliott - WAS @ DAL ($8,000)

After laying an egg against Philly in Week 16, the Dallas Cowboys are now in "must win" mode in this matchup against Washington. Due to that fact, I expect Dallas to rely on their best player, Ezekiel Elliott. The Cowboys offense should attempt to win this one by attacking the Redskins on the ground, an area where Washington has struggled mightily. The 'Skins have allowed 1,790 yards to opposing RBs - the third-most yards allowed in the NFL - and stand 30th in the league in DK Points relinquished to the position. Elliott has looked good when given opportunities over the past month and there's a strong chance that he carves up this Washington defense that allowed almost 300 total yards to Saquon Barkley last week.

Kenyan Drake - ARI @ LAR ($7,100)

This definitely feels "point chasey", but that doesn't make it a bad play. Kenyan Drake has been a revelation for the Cardinals after years of being imprisoned by Adam Gase in Miami. Finally free, Drake has been ridiculous for Arizona over the past couple of weeks, rushing for 303 yards and six(!) TDs on 46 combined carries against the Browns and Seahawks. The combination of a banged-up Kyler Murray and Drake's hot hand should help him once again see a huge workload this week against a Rams team that has been eliminated from playoff contention. The LA run defense has been non-existent recently, and has relinquished over 100-yards rushing in four of their last five, including allowing both Zeke Elliott and Tony Pollard to go over the century mark in Week 15.

*SATURDAY UPDATE: Still feel great about all the RBs listed above. Carolina's Christian McCaffrey will be chasing records this week and not much else, so you can expect his volume to be extremely heavy (as usual). Green Bay's Jamaal Williams has been ruled out which should push DFS players to roster Aaron Jones in droves. Though he'll now be chalk at an expensive price, the only concern we ever have with Jones is volume, which he should now get plenty of. If you are looking lower down the salary scale at RB this week, I'm totally fine going back to the DeAndre Washington well. He was a player that we highlighted in this article last week and filled in admirably for Josh Jacobs. Washington should once again see a substantial workload against Denver with Jacobs still out. It's always tough to trust Patriots running backs, but I am intrigued by Sony Michel against the horrible Dolphins run defense. He's TD dependent, but Michel has received 40 total carries over the last two weeks.

 

DraftKings DFS Wide Receivers - Week 17 Picks

Julio Jones - ATL @ TB ($8,500)

Motivation is a big theme this week, and while the Falcons "have nothing to play for", they seem dead set on closing out this season in a fashion that saves coach Dan Quinn's job. They've continued running their studs out and I don't anticipate anything changing in that regard this week...although Julio Jones has popped up with a 'Questionable' tag, so keep an eye on that. Since Calvin Ridley went down with an injury two weeks ago, Jones has been BEASTING...racking up 23 catches for 300 yards and 2 TDs on a ridiculous 35 targets. He brings those video-game numbers into a matchup against a Bucs defense that is DEAD LAST in the league in yards allowed to opposing wide receivers. The matchup and potential game environment doesn't get any better, and if Jones continues to see anywhere near the volume he's had in recent weeks a slate-breaking score wouldn't be surprising.

Justin Watson - ATL @ TB ($4,900)

With the plethora of injuries the Bucs have suffered in the wide-receiving corps, we can safely turn our eyes to Breshad Perriman and Justin Watson. Perriman's price tag has gotten a bit out of hand, so I'll side with the cheaper Watson here. Watson played 70 of Tampa's 72 snaps last week, receiving 10 targets in the Week 16 game against Houston, converting those looks into five catches for 43 yards and a TD. He gets a prime matchup against an Atlanta defense that has relinquished nearly 2,500 yards to opposing WRs and ranks 30th in the NFL by allowing 9.36 yards per target to the position.

Steven Sims Jr. - WAS @ DAL ($4,700)

I touched on Case Keenum earlier in the article and if you're a believer in that play and need to save salary, you can pair Keenum with Washington's emerging receiver Steven Sims Jr. The undrafted rookie out of Kansas has seen increased playing time over the past month and has made the most of his opportunity, racking up 15 catches for 149 yards and three TDs on a massive 28 targets over Washington's last three games. With the 'Skins alpha-receiver Terry McLaurin still in the NFL concussion protocol as of this writing, Sims is in line to get all the work he can handle in this one.

*SATURDAY UPDATE: If paying up at WR, Michael Thomas, Julio Jones, and Davante Adams are the clear top options with Adams being an especially intriguing GPP pivot play with Aaron Jones expected to be so popular. Chris Godwin has been ruled out which keeps the active Bucs receivers in consideration. Terry McLaurin has been ruled out for Washington. That makes Steven Sims Jr the primary option in this depleted 'Skins passing attack and even brings a player like Kelvin Harmon at $3.9k into consideration.

 

DraftKings DFS Tight Ends - Week 17 Picks

Tyler Higbee - ARI @ LAR ($5,600)

I'm not gonna let the regular season end without targeting the Arizona Cardinals with a tight end at least one more time. If you are a regular reader of this article then you know this matchup is a "cheat code" that we've exploited as often as possible due to the Cards' historical ineptitude against the position. In addition to routinely targeting Arizona, I've been writing up LA's Tyler Higbee seemingly every week for the past month. Since Gerald Everett went down with an injury in Week 12, Higbee has - I can't believe I'm saying this - looked like one of the best tight ends in football. He's went over 100-yards receiving in four-straight games and has been targeted a RIDICULOUS 44 times in that span. My only concern here is that the Rams have very little to play for, but Higbee played almost every snap for the Rams last week despite Gerald Everett's return. I'm optimistic we can pencil him in for a solid workload, but it's a situation that I'll monitor up until kickoff.

Dallas Goedert - PHI @ NYG ($4,900)

This is another situation to monitor, with Philly heading into a "must win" game against New York with their star TE Zach Ertz very banged up. Ertz missed a large portion of last week's game against Dallas with a rib injury, which resulted in his running mate Dallas Goedert being targeted 12 times. The second-year TE converted those looks into nine catches for 91 yards and a TD. If Ertz can't go, Goedert becomes an obvious slam-dunk play in this spot...and even if Ertz does try to tough it out, it wouldn't be at all surprising if he's very limited.

*SATURDAY UPDATE: Philly's Zach Ertz has officially been ruled out, so lock and load Dallas Goedert with confidence. I'm feeling a little shaky about Tyler Higbee - not because he's not an awesome play - but due to the fact that there have been some reports that the Rams might rest key players in this meaningless game. KC's Travis Kelce is always in play if you don't mind spending up. The matchup is brutal, but Miami's Mike Gesicki has benefited greatly from Ryan Fitzpatrick's care-free aggressiveness.

 

DraftKings DFS Defenses - Week 17 Picks

Pittsburgh Steelers Defense - PIT @ BAL ($3,000)

I'm only listing one D/ST this week because I don't know that I'll roster any unit outside of Pittsburgh in my own builds. The Steelers have consistently been one of the top defensive units in the league this year. They head into a "must win" situation against the Ravens, will be facing an offense that's resting their starters, and have a reasonable price tag of just $3k. It all feels like a recipe for success and one I'm not going to overthink.

*SATURDAY UPDATE: I'm still planting my flag on the Steeler hill, but there are some other good options out there. If you're spending up New England and New Orleans are both great choices. I also like the Green Bay D/ST against the Lions in a spot where the Packers will be going all out.

More Weekly DFS Analysis




REAL-TIME FANTASY NEWS

Kevin Huerter

is Cleared to Return for Game 5
Caris LeVert

is Available for Game 5 on Wednesday
Duncan Robinson

is Out for Game 5
Keegan Murray

Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Sam Malinski

Set to Miss Second Straight Game
Artturi Lehkonen

Unlikely to Play Wednesday
Matthew Schaefer

Wins Calder Trophy
TOR

Maple Leafs Fire Head Coach Craig Berube
Jalen Hurts

Can Jalen Hurts Bounce Back as a Rusher in 2026?
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Zach Charbonnet

Dynasty Value in Question Entering 2026
DeVonta Smith

Poised to Reach a New Level of Production in 2026?
Chris Olave

Facing Increased Target Competition in New Orleans Entering 2026
Chris Bell

Dynasty Stock Rising Following NFL Draft
Ted Hurst

Facing Uphill Battle for Playing Time in Tampa Bay
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
Chris Brazzell II

Is Chris Brazzell II the Top Deep Threat in Carolina's Receiver Room?
Kaelon Black

a Threat to Win Backup RB Job in San Fran?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
De'Zhaun Stribling

to be 49ers' New "F" Receiver?
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
Drew Allar

Steelers "Uninstalling" Everything Drew Allar Learned in College
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Ja'Kobi Lane

Is Ja'Kobi Lane the Pass-Catching Answer the Ravens Have Been Seeking?
Zachariah Branch

Does Zachariah Branch Have a Path to Immediate Production?
Max Klare

Can Max Klare Separate Himself in Rams' Tight End Room?
Eli Stowers

the Tight End of the Future in Philadelphia?
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Germie Bernard

Already in a Tough Spot to Hold Dynasty Value
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Denzel Boston

a Smart Bet to Meet or Exceed Value in Dynasty Rookie Drafts
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Matthew Stafford

a Sell Candidate with Touchdown Regression Likely on its Way
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

Comes Alive in Game 5 Against Timberwolves
Jayden Reed

Dynasty Value Tethered to His Underwhelming Usage
Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Kenyon Sadiq

Is Kenyon Sadiq the Next Great Rookie Tight End?
Victor Wembanyama

Leads Spurs to Big Win in Game 5
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Mason McTavish

Delivers Two Assists Tuesday Night
Pavel Dorofeyev

Pots Two Goals in Vital Game 5 Win
Josh Doan

Records Two Assists in Game 4 Victory
Evgeni Malkin

Penguins Want Evgeni Malkin Back
Sidney Crosby

Joins Team Canada for World Championship
Ryan Poehling

Suffers Upper-Body Injury in Game 5 Loss
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Cade Klubnik

Becoming Fan Favorite, in Play to Win Backup QB Job?
Michael Penix Jr.

Throwing During Offseason Program
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Dylan Harper

Cleared for Action Tuesday
De'Aaron Fox

Available for Game 5 Against Timberwolves
Caris LeVert

Remains on Injury Report With Heel Issue
Duncan Robinson

Listed as Questionable for Game 5
Memphis Grizzlies

Brandon Clarke Dies at Age 29
Charlie McAvoy

Slapped With Six-Game Suspension
Jonas Brodin

Unavailable for Game 5 Against Avalanche
Joel Eriksson Ek

to Remain Out Wednesday
Sam Malinski

Day-to-Day With Upper-Body Injury
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Artturi Lehkonen

Considered Day-to-Day
Charlie Coyle

Lands Six-Year Extension
Ukko-Pekka Luukkonen

to Start Game 4 Against Canadiens
Drew Helleson

Unavailable for Game 5
Radko Gudas

Still Out Tuesday
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
Luka Dončić

Luka Doncic Admits He Wasn't Close to Returning Before Season Ended
CFB

Isaac Brown Has All-American Upside in 2026
LeBron James

Uncertain About Future After Season-Ending Loss
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
Luis Castillo

Mariners Intend to Piggyback Luis Castillo, Bryce Miller
Logan Webb

Placed on 15-Day Injured List With Knee Bursitis
Bryce Miller

is Set to Return on Wednesday
Jeff Hoffman

Could Return to Closer Role
Taj Bradley

Hits the Injured List With Pectoral Inflammation
Kyle Bradish

has Nice Bounce-Back Performance With 10 K's
Casey Mize

Throws Bullpen on Friday, Return Not Imminent
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
CFB

Rasheem Biles an Instant Impact Player for Texas
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