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Week 6 Running Back Rankings & Matchups Analysis

Below you will find our Week 6 running back rankings, to help determine your RB starts/sits for this week, brought to you by Bill Dubiel (@Roto_Dubs), Nick Mariano (@NMariano53) and Ben Ruppert (@Ben_Ruppert_21).

Featured writer Ben Ruppert also highlights some RB rankings and matchups analysis for Week 6, and draws some matchup conclusions. He tells you who he likes, who he doesn't, and most importantly who he thinks you should be starting in Week 6. You can also check out RotoBaller's overall player rankings here.

Editor's Note: Be sure to check out FantasyAces DFS contests for Week 4. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

Week 6 Running Backs - Rankings & Matchups Analysis

Ezekiel Elliott will have a difficult time this week against the top ranked run defense in the league, the Green Bay Packers. Over his past three games, Elliott has averaged 23 rushes for 137 yards and a TD per game. He has really begun to take advantage of his dominant offensive line, which most weeks will do him extremely well. However, he has yet to face a defense anywhere near this difficult. The past three teams he has faced have averaged 4.4 YPC allowed, compared to the Packers 2.2 YPC. He certainly won’t keep up his 100 yard streak this week, but he will likely score a TD to keep his fantasy impact high.

I thought last week would be the week Lamar Miller finally punched one in, but that prediction ended up being a liiiiiittle too bold. It was easily the worst week Miller has had this season against a defense that could stop a train with a napkin right now. This week he faced a much softer run defense in with the Indianapolis Colts. They have allowed the third most fantasy points to RBs this season, while allowing nearly a TD per game. If there will be a game Miller breaks out, it’ll be this one. This is easily the softest run defense he has faced this season.

If you look past the Bills ugly defensive performance in Week 2, you will see they have been one of the top defenses in the league this season. Carlos Hyde and the 49ers head to Buffalo this week, with Colin Kaepernick at QB. Kaep should help open up some holes with his legs, but Hyde will still have a tough time running through this defensive line with Marcell Dareus now back in the fold. Hyde has ran through tough defenses before, as evidenced by his Week 3 performance against Seattle (21 rushes for 103 yards and two scores). Hyde still has tons of potential, but keep expectations in check against this defense.

On the flip side, if there is a RB out there who will unseat Le’Veon Bell or David Johnson this week, it will be LeSean McCoy. The 49ers defensive weaknesses play into what the Bills do well offensively, mainly running the ball. Shady is having an excellent year so far, averaging 5.3 YPC and 21 touches per game on the ground and through the air. He already topped his TD total from last season, and is fresh off of his best game of the season against the LA Rams. The 49ers have allowed the fifth most fantasy points to opposing RBs, while allowing the most rushing YPG in the league at 133.4 yards. Shady is going to dominate this week.

Fresh off of their bye week, the Chiefs are set to take the training wheels off of RB Jamaal Charles against the Oakland Raiders. Oakland is among the bottom 10 teams in the league in stopping the running game, and is fresh off of allowing Melvin Gordon to rush for 4.3 YPC, while catching a receiving TD. Last time Charles played Oakland he was all over the field, rushing for 80 yards on 19 carries while catching four passes for 42 yards and a score. The only thing keeping Charles from being higher up on this list is we won’t know the volume of touches he will receive this week. If he gets a full work load, watch out.

Devonta Freeman and Tevin Coleman have been an extremely effective two-headed monster for the Falcons this season, so much so that if they were both started by fantasy owners each week you would be very happy. However, this week they face a Seattle defense that will be different than any run defense they have faced this season. Seattle has only allowed 66.5 rushing YPG from opposing RBs, but have also given up 47.8 YPG through the air. Freeman has dominated the ground game, and both backs have caught a similar number of passes. Coleman though has done much more damage in the receiving game this season, out-gaining Freeman 313-to-117 with only three more catches.  With running holes hard to come by and Richard Sherman shadowing Julio Jones, expect a lot of receptions by these backs. I would not be surprised to see Coleman outscore Freeman in fantasy this week.

Jonathan Stewart will make his return from injury this week, and could not have a better matchup. This week the Panthers head to New Orleans to face the Saints, who have allowed the most points to opposing RBs this season. Stewart is fully recovered from the hamstring injury he suffered in Week 2, and will immediately reclaim his role as the top RB over Fozzy Whittaker and Cameron Artis-Payne.  Cam Newton will also return this week after sustaining a concussion against the Falcons in Week 4. With their fully bevy of weapons back, Stewart will be ready to feast on the ground and through the air against this Swiss-cheese defense. As the 38th RB on our list, Stewart is ranked criminally low for the upside he brings this week.

 

Week 6 Fantasy Football Rankings - Running Backs

Rank Player Name Pos
3 Le'Veon Bell RB
4 David Johnson RB
7 DeMarco Murray RB
10 LeSean McCoy RB
13 Ezekiel Elliott RB
17 Lamar Miller RB
18 Todd Gurley RB
23 Theo Riddick RB
27 Jordan Howard RB
28 Mark Ingram RB
31 C.J. Anderson RB
32 Carlos Hyde RB
37 Devonta Freeman RB
39 Melvin Gordon RB
40 Christine Michael RB
50 Eddie Lacy RB
53 Matt Forte RB
55 Ryan Mathews RB
56 Jamaal Charles RB
57 Frank Gore RB
59 Giovani Bernard RB
61 Tevin Coleman RB
62 James White RB
68 Isaiah Crowell RB
73 Terrance West RB
74 LeGarrette Blount RB
78 Duke Johnson RB
79 Arian Foster RB
81 T.J. Yeldon RB
82 Spencer Ware RB
84 Matt Jones RB
86 Darren Sproles RB
87 Bilal Powell RB
100 DeAndre Washington RB
102 Jeremy Hill RB
108 Chris Ivory RB
111 Chris Thompson RB
112 Jonathan Stewart RB
114 Devontae Booker RB
115 Fozzy Whittaker RB
119 Cameron Artis-Payne RB
120 Latavius Murray RB
121 Rashad Jennings RB
122 Jalen Richard RB
126 Jay Ajayi RB
127 Bobby Rainey RB
135 Derrick Henry RB
137 C.J. Spiller RB
143 James Starks RB
148 Kenneth Dixon RB
156 DeAngelo Williams RB
157 Mike Gillislee RB
161 Orleans Darkwa RB
165 Wendell Smallwood RB
168 Jamize Olawale RB
170 Damien Williams RB
175 Javorius Allen RB
177 Alfred Morris RB
180 Jeremy Langford RB
183 Zach Zenner RB
186 Josh Ferguson RB
189 Dwayne Washington RB
195 Dexter McCluster RB
197 Travaris Cadet RB

Check out all of RotoBaller's fantasy football rankings. Staff rankings are updated regularly for all positions and include standard formats, PPR scoring, tiered rankings and dynasty leagues.




REAL-TIME FANTASY NEWS

Jordan James

Most Likely to be 49ers' RB2 in 2026
Mickey Moniak

Heads to Injured List With Ankle Sprain
Rudy Gobert

Earns Eighth All-Defensive First-Team Selection
Victor Wembanyama

Headlines 2025-26 All-Defensive First Team
Ajay Mitchell

Starting Game 3 Against Spurs
Dylan Harper

Available for Game 3 Against Thunder
De'Aaron Fox

Returns to Action Friday
Jalen Williams

Won't Play Friday Night
Derrick Henry

Remains in RB1 Discussion
Ladd McConkey

is Solid Buy-Low Candidate
Ryan Flournoy

an Intriguing Dynasty Stash Option
Jalen Nailor

is Expected to Have Larger Role in Las Vegas
Frederik Andersen

Hurricanes Keep Faith in Frederik Andersen
Devon Levi

Attracting Interest From Senators
Jacoby Brissett

Cardinals Not Close to a Reworked Deal
Scott Wedgewood

Starting Game 2 Against Golden Knights
Ben Hutton

Scratched for Game 2 Against Avalanche
Mark Stone

Won't Play Friday
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
Cale Makar

Remains Out Friday
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
NFL

Evan Stewart Pushing Oregon Receiving Corps
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
New York Giants

Giants, GM Joe Schoen Agree on a Multi-Year Extension
Andrew Thomas

Giants Managing Multiple Injuries for Andrew Thomas
Cam Ward

Loses 10 Pounds in the Offseason
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Tucker Kraft

a Top Trade Target in Dynasty Leagues?
Cedric Tillman

Falling Out of Favor in Cleveland
Emmett Johnson

the Handcuff to Roster in Kansas City?
Devaughn Vele

Could Dynasty Managers Sell High on Devaughn Vele Early in the Season?
Brenen Thompson

a Perfect Fit for Chargers, Rising in Dynasty Leagues?
Jonathan Taylor

Is Jonathan Taylor Still a High-End Dynasty Option?
Malik Nabers

' Recovery Timeline Still Unclear
Jaxon Smith-Njigba

Comfortably Into His Dynasty Prime
Saquon Barkley

Still a Capable League-Winner at a Sunken Dynasty Cost
Jack Campbell

Signs Four-Year Extension with Lions
Matthew Stafford

Signs One-Year Extension with Rams
Evan Mobley

Fills the Box Score in Game 2 Loss
James Harden

Held to Two Assists Thursday
Donovan Mitchell

Leads Cavaliers in Scoring in Game 2 Defeat
Karl-Anthony Towns

Records Double-Double in Game 2 Win
Sebastian Aho

Picks Up an Assist in Series-Opening Loss
Mikal Bridges

Adds 19 Points as Knicks Grab 2-0 Lead
Jalen Brunson

Hands Out 14 Assists in Game 2 Win
Seth Jarvis

Needs 33 Seconds to Score in Game 1 Loss
Josh Hart

Erupts for Playoff Career-High 26 Points in Game 2
Jaccob Slavin

Struggles in Game 1 Against Canadiens
Jakub Dobes

Sharp in Game 1 Victory
Cole Caufield

Bags Two Points in Impressive Road Win
Juraj Slafkovsky

Opens Conference Finals With Three-Point Performance
Nick Suzuki

Notches Three Assists in Game 1 Win Over Hurricanes
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Jrue Holiday

Wants to Stay in Portland
Ayo Dosunmu

Timberwolves Hope to Bring Back Ayo Dosunmu
Dylan Harper

Considered Questionable for Friday Night
De'Aaron Fox

Listed as Questionable for Game 3
Jalen Williams

Questionable for Game 3 Against Spurs
Alex Tuch

Hopes to Remain in Buffalo
Sidney Crosby

Wants to Play for "as Many Years as Possible"
Troy Terry

Could Miss Start of Next Season Due to Hip Surgery
Arber Xhekaj

Scratched for Game 1 of Eastern Conference Finals
Jakub Dobes

Seeks More Success Against Hurricanes
Frederik Andersen

Looks to Stay Undefeated Thursday
Robby Snelling

Will Undergo Tommy John Surgery
Devin Vassell

Contributes 22 Points in Wednesday's Loss
Stephon Castle

Tallies Team-High 25 Points in Game 2 Loss
Victor Wembanyama

Records Eighth Postseason Double-Double
Valeri Nichushkin

Ends Scoring Slump in Game 1 Loss
Nathan MacKinnon

Extends Point Streak With an Assist
Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
CFB

Lincoln Riley Believes USC is Ready for Playoff Run
CFB

Notre Dame-Stanford Rivalry Renewed Through 2028
CFB

Ahmad Hardy Says He's "Back to the Road to Success"
CFB

Texas Tech Graduate Judge Recuses Himself from Brendan Sorsby Case
CFB

UCLA Tackle Jordan Davis Officially Eligible for 2026 Season
CFB

Bret Bielema Supports Significant College Football Playoff Expansion
Michael Thorbjornsen

Brings High Upside to CJ Cup Byron Nelson
Luke List

Carrying Poor Form Into CJ Cup Byron Nelson
Tom Kim

Hoping to Build on Strong Myrtle Beach Finish
PGA

Sungjae Im Brings Upside to TPC Craig Ranch
Billy Horschel

Looking for Turnaround at CJ Cup Byron Nelson
Adam Hadwin

Difficult to Trust at TPC Craig Ranch
Tony Finau

Looking for Consistency at TPC Craig Ranch
Luke Clanton

Searching for Form at CJ Cup Byron Nelson
Aaron Rai

Withdraws From CJ Cup Byron Nelson
Wyndham Clark

Can Wyndham Clark Find Form at CJ Cup?
Si Woo Kim

Looks To Stay Hot at CJ Cup
Scottie Scheffler

to Defend CJ Cup Byron Nelson Title This Week
Jordan Spieth

Looking For Victory at TPC Craig Ranch
PGA

Matti Schmid Looks to Keep Recent Momentum Going at TPC Craig Ranch
Brooks Koepka

a High-Upside Play at CJ Cup Byron Nelson
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Gerrit Cole

to Make Season Debut on Friday Against Rays
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
CFB

Kemario Taylor a Breakout Candidate at Quarterback
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Corey Seager

Going on Injured List With Back Injury
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF