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DraftKings Daily Fantasy Football Lineup Picks (Week 5): NFL DFS Advice

Jason Bales' week five DraftKings lineup picks. Daily fantasy football sleepers, value picks and lineups advice for DraftKings DFS games and tournaments.

Welcome to RotoBaller's Daily Fantasy football DraftKings lineup picks for Week 5 of the NFL season. In this article, I, Jason Bales, will be taking you, the reader, through the best DraftKings DFS plays of the week for this upcoming Sunday.

These DraftKings lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 5. Good luck with your DraftKings DFS lineups!

Editor's Note: If you like DraftKings, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Be sure to check all of our fantasy football rankings for 2025:

 

DraftKings Quarterbacks - Week 5 DFS Picks

Tom Brady (at CLE, $7,500)

Tom Brady is returning this week. It is all over the ESPN headlines, and he should definitely be on that good ol' reliable fantasy radar. He has yet to play a game this season, obviously, so taking a look at prior weeks will do us no good here. He is one of the best quarterbacks in the league, and he has been for years. He is not going to come out against the Cleveland Browns and disappoint. The New England Patriots have been scoring points without him, so the damage that is likely to ensue this week is tremendous. Brady will score touchdown after touchdown, looking into the camera, Goodell on his mind each time. This is a statement game for Brady, and he tends to play well in statement games. Look out, NFL. The tiger has been poked, and he is finally out of his cage.

 

DraftKings Running Backs - Week 5 DFS Picks

Jordan Howard (at IND, $5,200)

Jordan Howard started the season in a position battle with Jeremy Langford, but with his performance last week, he won. Head coach John Fox reported that Howard will be the workhorse for the Bears for the foreseeable future. That is great news for fantasy owners, and his price tag on DraftKings is still a little bit too low. The Indianapolis Colts' rush defense is soft, and the Bears will need a strong rushing attack, if they are going to win this game. Last week, Howard touched the ball 26 times (23 rush attempts, three receptions) for over 130 total yards. He neglected to find the end zone, but with that many touches, he will cross the goal line eventually. Use him in both 50/50 contests and tournaments this week. The job is his to lose.

DeAndre Washington (vs SD, $3,400)

DeAndre Washington has been one of the best change of pace running backs in the NFL since week one. Against the Atlanta Falcons, he rushed for 46 yards on only seven touches. Against the Tennessee Titans, he rushed for 57 yards on only six touches. Against the Baltimore Ravens, he rushed for 30 yards on only five touches. He also caught five balls over that three game time span. Now, Latavius Murray is out of the Oakland Raiders' starting lineup with a toe injury. Washington will touch the ball around 20-25 times this week, and his upside is on TERROR ALERT RED. The San Diego Chargers love to turn games into shootouts, but the Raiders will feed Washington the ball over and over again in an effort to control the clock. His price tag is a steal.

 

DraftKings Wide Receivers - Week 5 DFS Picks

Odell Beckham Jr. (at GB, $8,500)

Odell Beckham Jr. is constantly getting picked on for his uncontrollable temper tantrums on the field, and while that may be a hot (and hilarious - at least, in regards to his fight with a net) topic of conversation, it does not impact his fantasy value. This season, he only has 303 receiving yards on 22 receptions in four games, but do not abandon ship. This week, he gets a great matchup against the Green Bay Packers, and after announcing that he is no longer having fun playing football, he will likely return to the field and have himself some fun in the form of a boatload of receptions and possibly a touchdown or two. Beckham is easily one of the best talents in the league at his position, and his own-percentage is likely down right now, especially with everyone boarding the Julio Jones' train. Take advantage of that in tournaments.

Brandon Marshall (at PIT, $7,100)

Brandon Marshall is never included in the 'who are the best wide receivers in the league' dialog, but he probably should be. In his last two starts, he has double-digit targets in both of them, showing off how important he is to Ryan Fitzpatrick and the New York Jets' offensive game plan. So far this season, he has seen some very stiff competition, but still managed to produce over 18 fantasy points in two of his four games. The Pittsburgh Steelers are solid defensively, but this game, unlike a lot of Jets' games, should turn into a shootout. The Steelers love to score points, and if they are scoring, the Jets will be throwing. This opens up a lot of opportunity for Marshall, and his price tag is much lower than that of even Jordy Nelson or Alshon Jeffery. Use him in all formats.

 

DraftKings Tight Ends - Week 5 DFS Picks

Zach Ertz (at DET, $3,500)

Zach Ertz looked great week one against the Cleveland Browns, catching six of seven targets for 58 yards. Unfortunately, he injured his rib, an injury that kept him out of the last two games. He is set to return this week against the Detroit Lions, a team that does not cover the tight end very well. Ertz's price tag is down right now, but his production should not be impacted by his prior injury. He practiced in full all week long, and he is ready to go, especially coming off a bye week. The Eagles are going to look toward Ertz early and often, as Carson Wentz loves to check down when available. The Eagles' starting tight end should easily hit value, making him one of the best plays at any position this week.

 




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REAL-TIME FANTASY NEWS

Tyler Bertuzzi

Set to Return Thursday
Gary Harris

Added to the Injury Report as Questionable for Thursday
Daniel Jones

Added to Colts' Injury Report With Calf Issue
Andrew Wiggins

Unavailable For Friday's Matchup With Chicago
Indiana Pacers

Garrison Mathews Will Join the Pacers
Joe Burrow

Logs Second Straight Full Practice on Thursday
Dante Exum

Will Miss the Rest of the Season
Keegan Murray

Is Available For His Season Debut Thursday
Tyrese Maxey

Listed as Probable for Thursday
Domantas Sabonis

Will Not Play Thursday Against Memphis
Joel Embiid

Listed as Out for Thursday
Aaron Rodgers

Seen at Practice on Thursday
Jaylen Warren

Moving Around Well on Thursday
Bucky Irving

Will be on a Snap Count When he Returns
Jaxson Dart

Could Clear Concussion Protocol Thursday
Lamar Jackson

Returns to Thursday's Practice
Josh Jacobs

to Do Individual Drills on Thursday
Joe Mixon

Not Expected to Play This Season
Chris Godwin

Attending Thursday's Practice
Bucky Irving

Continues Practice Attendance
Rasmus Andersson

Bags Three Points Wednesday Night
Morgan Geekie

Nets Two Power-Play Goals Wednesday
Joe Burrow

Bengals Haven't Ruled Out Joe Burrow for Week 12
Connor McMichael

Posts Three Assists in Wednesday's Win
Alexander Romanov

Islanders Place Alexander Romanov on Injured Reserve
Lars Eller

to Miss Thursday's Action
Nic Dowd

Out on Thursday
Adam Lowry

Inks Extension With Jets
Jaren Jackson Jr.

Likely Out on Thursday
Zaccharie Risacher

Questionable for Thursday
Kristaps Porzingis

at Risk of Missing Another Game
Paolo Banchero

Misses Fourth Straight Game
Kawhi Leonard

Remains Out Against Magic
Kelly Oubre Jr.

Ruled Out for Two Weeks
Tyler Herro

Targeting Return on Monday
Brian Thomas Jr.

Limited in Practice on Wednesday
Jerami Grant

Available Wednesday Night
Jalen Brunson

Returns From Two-Game Absence
Jalen Smith

Available to Play Wednesday
Tre Jones

Downgraded to Out
Shaedon Sharpe

Misses Wednesday's Game
Dereck Lively II

Cleared for Action Wednesday
Raisel Iglesias

Returning to the Braves on One-Year Deal
Lamar Jackson

Absent Due to Ankle Injury
Conor Garland

to Return on Thursday
Thomas Harley

to Miss Road Trip
Eetu Luostarinen

Out Week-to-Week After Barbecue Accident
Curtis Lazar

to Miss at Least Three Games
Vladimir Tarasenko

Misses Third Consecutive Game
Mikael Granlund

Remains Out Wednesday
Charlie McAvoy

Out Indefinitely After Facial Surgery
Joe Burrow

to Potentially Return in Week 12?
Aaron Rodgers

Out on Wednesday, Hopes to Practice Thursday
Jaylen Warren

Not Seen at Wednesday's Practice
Dak Prescott

Lands on Injury Report Ahead of Week 12 With Hip Injury
Rhamondre Stevenson

Targeting a Return in Week 12?
Isiah Pacheco

Returning to Practice on Wednesday
Brian Thomas Jr.

Jaguars "Optimistic" About Brian Thomas Jr.'s Week 12 Status
Sahith Theegala

Looking to Continue Fall Run at RSM Classic
Stephan Jaeger

Looking to Bounce Back at RSM Classic
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Looking to Regain Form at RSM Classic
Joe Highsmith

Searching for Turnaround at RSM Classic
Adam Hadwin

Looking to Build on T11 Finish in Bermuda
Austin Eckroat

Searching for Momentum at RSM Classic
Joel Dahmen

Trying to Find Form at the RSM Classic
CFB

Garrett Nussmeier Doubtful to Play Against Western Kentucky
Connor Bedard

Continues Tear With Hat Trick
Macklin Celebrini

Pots Hat Trick in Tuesday's Win
Jake Guentzel

Records Eighth Career Hat Trick
Sammy Blais

Injured Versus Blues
Alexander Romanov

Injured in Tuesday's Win
Ryan Hartman

Considered Week-to-Week
Michael Thorbjornsen

Hopes to End 2025 Campaign With Another Solid Finish
Andrew Novak

Looks to End 2025 Season on High Note at RSM Classic
Harry Higgs

Teetering for PGA Tour Card in 2026
PGA

Nico Echavarria has the Potential to Contend at the RSM Classic
Sam Stevens

Finishing Out Year in Georgia
Seamus Power

Playing Better at the Right Time
Beau Hossler

Roller Coaster Comes to Saint Simons Island
Quade Cummins

The Time is Now for Quade Cummins in Georgia
Austin Cook

Needs a Win at the RSM Classic
Cameron Champ

on the PGA Tour Card Bubble
Grayson Rodriguez

Shipped to Angels
Taylor Ward

Orioles Acquire Taylor Ward From Angels
Shota Imanaga

Accepts Cubs Qualifying Offer
Brandon Woodruff

Returning to Milwaukee in 2026
Denny McCarthy

Looking For Another Solid Finish at RSM Classic
Si Woo Kim

Looking To Use Current Momentum to Flip Script at RSM Classic
Mackenzie Hughes

a Good Bounce-Back Candidate at RSM Classic
Harris English

Making 14th Start at This Week's RSM Classic
Konnor Griffin

Could Compete for Starting Shortstop Job in 2026
Gleyber Torres

Accepts Tigers Qualifying Offer
CFB

Sam Leavitt Set to Enter Transfer Portal?
Jose Altuve

Undergoes Foot Surgery
Alex Bregman

Red Sox Going for Either Alex Bregman or Pete Alonso?
CFB

James Franklin to be Virginia Tech's Next Head Coach
CFB

Fernando Mendoza the Clear Heisman Trophy Favorite?
CFB

Beau Pribula Has Chance to Face Oklahoma on Saturday
Jack Della Maddalena

Gets Dominated
Islam Makhachev

Claims UFC Welterweight Belt
Zhang Weili

Gets Outclassed
Valentina Shevchenko

Wins Unanimous Decision At UFC 322
Sean Brady

Suffers First-Round TKO Loss
Michael Morales

Remains Unbeaten
Leon Edwards

Suffers Second-Round Knockout Loss
Leon Edwards

Carlos Prates Becomes The First Man To Knock Out Leon Edwards
Beneil Dariush

Suffers Brutal First-Round Knockout Loss
Beneil Dariush

Benoit Saint Denis Knocks Out Beneil Dariush In 16 Seconds
Josh Naylor

Mariners Finalizing Five-Year Contract
CFB

Jeremiah Smith, Carnell Tate Not Dealing With Long-Term Injuries
CFB

Virginia Tech Close To Naming James Franklin As Head Coach
CFB

Garrett Nussmeier Doubtful vs. Arkansas On Saturday
Edwin Díaz

Blue Jays Interested in Signing Edwin Diaz?
Jacob deGrom

Named AL Comeback Player of the Year
Ronald Acuña Jr.

Ronald Acuna Jr. Wins NL Comeback Player of the Year Award
Aroldis Chapman

Named AL Reliever of the Year
Edwin Díaz

Edwin Diaz Named NL Reliever of the Year

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