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DraftKings Daily Fantasy Football Lineup Picks (Week 5): NFL DFS Advice

Jason Bales' week five DraftKings lineup picks. Daily fantasy football sleepers, value picks and lineups advice for DraftKings DFS games and tournaments.

Welcome to RotoBaller's Daily Fantasy football DraftKings lineup picks for Week 5 of the NFL season. In this article, I, Jason Bales, will be taking you, the reader, through the best DraftKings DFS plays of the week for this upcoming Sunday.

These DraftKings lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 5. Good luck with your DraftKings DFS lineups!

Editor's Note: If you like DraftKings, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Be sure to check all of our fantasy football rankings for 2025:

 

DraftKings Quarterbacks - Week 5 DFS Picks

Tom Brady (at CLE, $7,500)

Tom Brady is returning this week. It is all over the ESPN headlines, and he should definitely be on that good ol' reliable fantasy radar. He has yet to play a game this season, obviously, so taking a look at prior weeks will do us no good here. He is one of the best quarterbacks in the league, and he has been for years. He is not going to come out against the Cleveland Browns and disappoint. The New England Patriots have been scoring points without him, so the damage that is likely to ensue this week is tremendous. Brady will score touchdown after touchdown, looking into the camera, Goodell on his mind each time. This is a statement game for Brady, and he tends to play well in statement games. Look out, NFL. The tiger has been poked, and he is finally out of his cage.

 

DraftKings Running Backs - Week 5 DFS Picks

Jordan Howard (at IND, $5,200)

Jordan Howard started the season in a position battle with Jeremy Langford, but with his performance last week, he won. Head coach John Fox reported that Howard will be the workhorse for the Bears for the foreseeable future. That is great news for fantasy owners, and his price tag on DraftKings is still a little bit too low. The Indianapolis Colts' rush defense is soft, and the Bears will need a strong rushing attack, if they are going to win this game. Last week, Howard touched the ball 26 times (23 rush attempts, three receptions) for over 130 total yards. He neglected to find the end zone, but with that many touches, he will cross the goal line eventually. Use him in both 50/50 contests and tournaments this week. The job is his to lose.

DeAndre Washington (vs SD, $3,400)

DeAndre Washington has been one of the best change of pace running backs in the NFL since week one. Against the Atlanta Falcons, he rushed for 46 yards on only seven touches. Against the Tennessee Titans, he rushed for 57 yards on only six touches. Against the Baltimore Ravens, he rushed for 30 yards on only five touches. He also caught five balls over that three game time span. Now, Latavius Murray is out of the Oakland Raiders' starting lineup with a toe injury. Washington will touch the ball around 20-25 times this week, and his upside is on TERROR ALERT RED. The San Diego Chargers love to turn games into shootouts, but the Raiders will feed Washington the ball over and over again in an effort to control the clock. His price tag is a steal.

 

DraftKings Wide Receivers - Week 5 DFS Picks

Odell Beckham Jr. (at GB, $8,500)

Odell Beckham Jr. is constantly getting picked on for his uncontrollable temper tantrums on the field, and while that may be a hot (and hilarious - at least, in regards to his fight with a net) topic of conversation, it does not impact his fantasy value. This season, he only has 303 receiving yards on 22 receptions in four games, but do not abandon ship. This week, he gets a great matchup against the Green Bay Packers, and after announcing that he is no longer having fun playing football, he will likely return to the field and have himself some fun in the form of a boatload of receptions and possibly a touchdown or two. Beckham is easily one of the best talents in the league at his position, and his own-percentage is likely down right now, especially with everyone boarding the Julio Jones' train. Take advantage of that in tournaments.

Brandon Marshall (at PIT, $7,100)

Brandon Marshall is never included in the 'who are the best wide receivers in the league' dialog, but he probably should be. In his last two starts, he has double-digit targets in both of them, showing off how important he is to Ryan Fitzpatrick and the New York Jets' offensive game plan. So far this season, he has seen some very stiff competition, but still managed to produce over 18 fantasy points in two of his four games. The Pittsburgh Steelers are solid defensively, but this game, unlike a lot of Jets' games, should turn into a shootout. The Steelers love to score points, and if they are scoring, the Jets will be throwing. This opens up a lot of opportunity for Marshall, and his price tag is much lower than that of even Jordy Nelson or Alshon Jeffery. Use him in all formats.

 

DraftKings Tight Ends - Week 5 DFS Picks

Zach Ertz (at DET, $3,500)

Zach Ertz looked great week one against the Cleveland Browns, catching six of seven targets for 58 yards. Unfortunately, he injured his rib, an injury that kept him out of the last two games. He is set to return this week against the Detroit Lions, a team that does not cover the tight end very well. Ertz's price tag is down right now, but his production should not be impacted by his prior injury. He practiced in full all week long, and he is ready to go, especially coming off a bye week. The Eagles are going to look toward Ertz early and often, as Carson Wentz loves to check down when available. The Eagles' starting tight end should easily hit value, making him one of the best plays at any position this week.

 




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REAL-TIME FANTASY NEWS

C.J. Stroud

to Miss Another Game
Jonathan Kuminga

Remains Out Tuesday
Keegan Murray

Could Make his Season Debut This Week
Caris LeVert

Liston as Out on Tuesday
Tobias Harris

Could Return Thursday
Ausar Thompson

Questionable Again on Tuesday
Joe Mixon

Uncertainty Remains Around Joe Mixon's Return Timeline
Cade Cunningham

is Questionable Tuesday in Atlanta
Jaylen Warren

Mike Tomlin Optimistic About Jaylen Warren's Availability for Week 12
C.J. Stroud

Not Expected to Play on Thursday Night
Aaron Rodgers

Won't Need Surgery on Fractured Wrist, Could Play in Week 12?
Davis Mills

Prepping for Third Straight Start in Week 12?
CFB

Sam Leavitt Set to Enter Transfer Portal?
Mason Rudolph

Could Make His First Start of 2025 in Week 12
Brock Wright

Sets Career-High in Targets; Lined Up for More Work?
Stephon Castle

Out Against Grizzlies
Kimani Vidal

Struggles Again and Faces Role Uncertainty After Bye
Dak Prescott

in Full Command Monday Night With Four Touchdown Passes
Quentin Johnston

Posts Zero Catches During Offensive Collapse
George Pickens

Erupts for 144 Yards, Touchdown in Monday Night Win
Jrue Holiday

Unlikely to Play Tuesday
CeeDee Lamb

George Pickens Benched for First Drive
LeBron James

Officially Listed as Questionable for Tuesday
Jose Altuve

Undergoes Foot Surgery
Giannis Antetokounmpo

Exits Monday's Game With Groin Injury
Julian Strawther

Out on Monday
Cameron Johnson

Cleared for Action Monday
Nikola Jokić

Nikola Jokic Available Against Bulls
Zaccharie Risacher

Considered Questionable for Tuesday's Game
Onyeka Okongwu

Iffy for Tuesday
Kristaps Porzingis

May Miss Another Game Tuesday
Jalen Suggs

Listed as Questionable for Tuesday
Paolo Banchero

to Remain Out Tuesday
Ayo Dosunmu

Playing on Minutes Restriction Monday
Tre Jones

Still Out Monday
Saddiq Bey

Won't Play Against OKC
Alex Singleton

Broncos Optimistic Patrick Surtain, Alex Singleton Will Return After the Bye
Trey Hendrickson

Doubtful Again in Week 12
Shedeur Sanders

Expected to Make First Career Start in Week 12
Josh Jacobs

Dealing With Knee Contusion
Mikael Granlund

Unavailable Monday
Alex Bregman

Red Sox Going for Either Alex Bregman or Pete Alonso?
Conor Garland

Misses Monday's Game
Eetu Luostarinen

Out on Monday
Drake London

Considered "Week-to-Week"
Drew Doughty

Listed as Week-to-Week
Ja'Marr Chase

Being Suspended for One Game for Unsportsmanlike Conduct
John Carlson

a Game-Time Call Monday
Viktor Arvidsson

Out Week-to-Week
Charlie McAvoy

Out Against Hurricanes
CFB

James Franklin to be Virginia Tech's Next Head Coach
Brandon Aiyuk

49ers Won't Open Brandon Aiyuk's Practice Window This Week
Joe Burrow

Could Do 11-on-11 Work This Week in Practice
CFB

Fernando Mendoza the Clear Heisman Trophy Favorite?
CFB

Beau Pribula Has Chance to Face Oklahoma on Saturday
Mitchell Marner

Establishes Vegas Record Sunday
Mats Zuccarello

Logs Two Assists in Overtime Victory
Lucas Raymond

Leads Red Wings to Victory at MSG
Quinn Hughes

Delivers Four Assists in Sunday's Win
Conor Garland

Limited to Handful of Minutes Sunday
Ryan Hartman

Suffers Lower-Body Injury
Adrian Kempe

Agrees to $85 Million Extension With Kings
Jack Della Maddalena

Gets Dominated
Islam Makhachev

Claims UFC Welterweight Belt
Zhang Weili

Gets Outclassed
Valentina Shevchenko

Wins Unanimous Decision At UFC 322
Sean Brady

Suffers First-Round TKO Loss
Michael Morales

Remains Unbeaten
Leon Edwards

Suffers Second-Round Knockout Loss
Leon Edwards

Carlos Prates Becomes The First Man To Knock Out Leon Edwards
Beneil Dariush

Suffers Brutal First-Round Knockout Loss
Beneil Dariush

Benoit Saint Denis Knocks Out Beneil Dariush In 16 Seconds
Josh Naylor

Mariners Finalizing Five-Year Contract
Scott Mayfield

Available Sunday
NYI

Max Shabanov Returns From 12-Game Absence Sunday
Samuel Honzek

Out Week-to-Week
Kirby Dach

Sidelined for 4-6 Weeks
Thatcher Demko

Considered Week-to-Week
Filip Hronek

Good to Go Sunday
Quinn Hughes

Back in Action Sunday
CFB

Jeremiah Smith, Carnell Tate Not Dealing With Long-Term Injuries
CFB

Virginia Tech Close To Naming James Franklin As Head Coach
CFB

Garrett Nussmeier Doubtful vs. Arkansas On Saturday
Edwin Díaz

Blue Jays Interested in Signing Edwin Diaz?
Jacob deGrom

Named AL Comeback Player of the Year
Ronald Acuña Jr.

Ronald Acuna Jr. Wins NL Comeback Player of the Year Award
Aroldis Chapman

Named AL Reliever of the Year
Edwin Díaz

Edwin Diaz Named NL Reliever of the Year
Justin Thomas

Will Miss Start Of 2026 After Undergoing Back Surgery
Islam Makhachev

Set For UFC 322 Main Event
Jack Della Maddalena

Set For His First Title Defense
Zhang Weili

Can Become The New Women's Flyweight Champion
Valentina Shevchenko

Set For UFC 322 Co-Main Event
Michael Morales

Looks To Remain Undefeated
CFB

Mario Craver a Game-Time Decision for Week 12
Sean Brady

Set For Title Eliminator Bout
Carlos Prates

A Favorite At UFC 322
Leon Edwards

Looks To Get Back In The Win Column
Benoît Saint Denis

Benoit Saint Denis Set To Open Up UFC 322 Main Card
Beneil Dariush

Looks To Win Back-To-Back Fights
CFB

Virginia's Chandler Morris Trending Toward Facing Duke on Saturday
Edwin Díaz

Edwin Diaz Says There's a "50-50" Chance he Returns to Mets
Shohei Ohtani

Wins his Fourth MVP Award
Aaron Judge

Wins AL MVP Award Again
Raisel Iglesias

Dodgers Interested in Signing Raisel Iglesias
Pete Alonso

Orioles Could be in the Mix to Sign Pete Alonso
Félix Bautista

Felix Bautista Could Return in Second Half in 2026
Kodai Senga

Attracting Trade Interest, Will the Mets Move him?
Yordan Alvarez

Expected to be Ready for Spring Training
Byron Buxton

Could Waive his No-Trade Clause
Paul Skenes

the Unanimous NL Cy Young Winner
Tarik Skubal

Wins AL Cy Young for Second Straight Year

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