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DraftKings Daily Fantasy Baseball Picks (9/22/19): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on September 22nd, 2019. Austyn Varney's MLB DFS analysis and sleepers for building optimal DFS rosters.

Welcome to Sunday baseball! The NFL is kicking off at 1 PM today, but so is baseball! DraftKings is still giving us big tournaments and the edge remains with a ton of fresh money on the sites. You have options no matter your price point, and the prize pools are all still huge. This is a fun slate. Runs will be scored and plenty of pitchers will have solid outings.

We'll be looking for the best play at each position. I'll be putting together a value article as well, so make sure to check that out as well. Let's dive in and find a top play at each position.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 9/22/19. The lineup picks will range from some of the elite players to mid-priced options and value plays. Be sure to also check out all the MLB Rosters for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. .

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DraftKings DFS Starting Pitchers

Yu Darvish - CHC vs. STL - $11,600

The Cubs are in dire need of a win at this point and it will be on the shoulders of Yu Darvish. He’s been playing the best baseball of his Cubs career, striking out 14 and 13 in back to back games. He now gets a Cardinals team that’s middle of the road against righties and strikeout 22% of the time. It looks like Verlander will be the chalk on this slate, and while he’s a bit safer than Darvish, I don’t think the Astros will stretch him all the way out at this point. Darvish will go over 100 pitches if pitching well and Madden will get all he can out of Darvish after the bullpen has blown it back to back nights.

Reynaldo Lopez - CWS @ DET - $7,400

Reynaldo Lopez is extremely unreliable and up and down, but this is the best match-up he can possibly have and if there’s ever a time for his ceiling to poke through it’s here. The Tigers rank dead last in baseball against righties with a team .280 wOBA and 25% strikeout rate. We’ve seen Lopez go for seven innings and strikeout 10 before, so it really just comes down to whether or not he can locate his pitches. We’re hoping for five or six dominant innings, but there is upside for a lot more.

 

DraftKings DFS Infielders

C - Tom Murphy - SEA @ BAL (Means) - $4,200

When the Mariners face off with a lefty, Tom Murphy brings a big bat to the lineup. He’s sported a .400+ wOBA against southpaws on the season and is averaging nearly a home run every 12 at-bats. The Mariners face off with John Means today, who’s given up a .336 wOBA to opposing right-handers. There’s a reason Murphy is priced up. He’s proven himself as a real threat when in the lineup against a lefty.

1B - Freddie Freeman - ATL vs. SF (Webb) - $4,700

With the Braves holding an expected run total of six, Vegas obviously expects Logan Webb to struggle on the road here. He’s had trouble with both sides of the plate on the season, giving up a combined .368 wOBA. Freeman is the heart of this Braves lineup and he’ll be involved in at least a couple of those runs one way or another. Against righties, his wOBA remains over .380. Logan Webb has looked reverse splits a bit, but the 25 inning sample size is nowhere near enough to judge that.

2B - Whit Merrifield - KC @ MIN (Perez) - $4,300

Whit Merrifield flies under the radar on most slates as the Royals really aren’t too exciting of an offense. They face off with Martin Pérez today, who’s always had some HR Issues with righties. He’s only getting worse and worse at this point and his combined wOBA is up to .341. The Royals are a team I like today that will go completely un-owned. I’m a believer that if Martin Pérez these guys can hit a ton of home runs. Whit, Soler, and Dozier are a great mini stack on all sites.

Renato Nunez - BAL vs. SEA (Gonzalez) - $3,900

Marco Gonzales is already a bit shaky with the long ball, and now he moves to Camden Yards. Renato Nunez is back in the lineup and he’s been a lefty masher all year long. He’s fallen off a bit of late, but is still sporting a .339 wOBA against lefties with double digit home runs. The Orioles can put up a ton of runs, and they’re very rarely popular. This is another slate where you can get a low-owned Orioles stack in Camden Yards at an affordable price.

Alex Bregman - HOU vs. LAA (Rodriguez) - $5,400

Jose Rodriguez will get around 50 pitches before Jose Suarez takes over in this one. It’s really all semantics against this offense who’s going to rough up whoever is on the mound. If you’d like to know, Rodriguez is actually pretty good, but he’s also been very lucky. Jose Suarez on the other hand, has been one of the worst pitchers in all of baseball against opposing righties. They’re all pretty expensive on DraftKings, but rightfully so. Vegas expects another six plus runs and you know generally where the production is coming from. Bregman has been great against both sides of the plate, posting a .382 wOBA on the season with 38 home runs and a 13% strikeout rate. Bregman is safe with a ton of upside.

 

DraftKings DFS Outfielders

Giancarlo Stanton - NYY vs. TOR (Tepera) - $4,000

Stanton has been good since returning from injury, and he’s still too cheap. Make sure he’s in there as this is a day game, but he should be after homering last night. Ryan Tepera isn’t very good himself and the bullpen will follow after just a few innings. It’s always tough to predict bullpen games, but it’s clear to me that I’d rather have Stanton than any Blue Jays bullpen arm and I’m willing to take my chances that he connects on one at that price on DK.

Jason Heyward - CHC vs. STL (Mikolas) - $3,900

Jason Heyward is too cheap on DraftKings for a guy that should be leading off. Mikolas has struggled with lefties all season long and the Cubs have hit him around a few times themselves. Heyward has sported a .356 wOBA against righties and he’s only gotten better as the year has aged. I don’t love this entire game for offense, but I don’t mind taking a flier on a cheap Jason Heyward.

Things change quickly as lineups come out. If you have any questions, hit me up on Twitter @VarneyDFS and I'd be more than happy to help.

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REAL-TIME FANTASY NEWS

Olivier-Maxence Prosper

Off Injury Report Wednesday
Ty Jerome

to Miss Fifth Straight Game
Caris LeVert

Available Tuesday Against Raptors
Miles McBride

to Suit up on Tuesday
Collin Murray-Boyles

Cleared to Play Tuesday
Marcus Sasser

is Available on Tuesday
Brandon Ingram

Returns Vs. Detroit
Ziaire Williams

Moves into Starting Five
Duncan Robinson

Active Vs. Toronto
Jalen Duren

is Back in Action on Tuesday
Tobias Harris

Available Tuesday
Marvin Bagley III

to Miss Second Straight Game
Ryan Rollins

Good to Go Tuesday
Klay Thompson

is Resting on Tuesday
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Returns Tuesday
Seiya Suzuki

to Begin a Rehab Assignment Soon
Simon Holmstrom

Misses Tuesday's Action
Marcus Smart

Out Against Cavs
Alexandre Carrier

Out 2-4 Weeks With Upper-Body Injury
Jordan Spieth

a Horse for Course History at TPC San Antonio
Mason Lohrei

Misses Second Consecutive Game Tuesday
Max Strus

Active on Tuesday
Tyler Myers

Unavailable Against Bruins
Robert MacIntyre

Has One Flaw to Overcome at Valero Texas Open to be a Must-Play
Michael Bunting

to Sit Out Tuesday's Game
Maverick McNealy

In Exceptional Form This Season
Michael Thorbjornsen

Playing Well But Still Searching For A Win
Hideki Matsuyama

Playing Well Heading to the Valero Texas Open
Si Woo Kim

Heads to Valero Texas Open For Final Tune-Up Before Masters
Sam Merrill

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Nikita Kucherov

a Game-Time Decision Tuesday
Evgeni Malkin

Ready for Action Tuesday
Jarrett Allen

Slated to Suit Up on Tuesday
Sam Bennett

Rejoins Panthers Lineup Tuesday
Jaylen Wells

Has Successful Surgery on Tuesday
Franz Wagner

Trending Toward Return
Cody Ponce

Diagnosed With ACL Sprain, to Miss "Significant Time"
Tank Dell

Uncertain for OTAs, But Expected to Play in 2026
Alvin Kamara

Saints Still Want to Address Alvin Kamara's Contract
George Pickens

Cowboys Have "Long-Term Plans" for George Pickens
Kyle Pitts Sr.

Falcons Not Ruling Out Potential Kyle Pitts Sr. Trade
Jordan James

the "Front-Runner" to be Top Backup RB
A.J. Brown

Patriots Still Not Ruling Out an A.J. Brown Trade
Aaron Rodgers

Planning to Re-Sign With Steelers?
Seattle Seahawks

Mike Washington Jr. Would Fill a Big Need for Seahawks
Los Angeles Rams

Kenyon Sadiq a Good Fit With the Rams?
Green Bay Packers

Packers to "Strip Everything Down" on Offense
Anthony Richardson Sr.

to Stay With Colts?
NFL

Ty Simpson has Visits With Cardinals, Dolphins, Browns
Aaron Rodgers

Mike McCarthy, Aaron Rodgers Touch Base
Cameron Ward

Mechanical Tweaks are Focused on his Footwork
Jaylen Waddle

to Play the Slot And Outside
Geno Smith

Aaron Glenn Thinks Geno Smith Will Lead Jets to "Promised Land"
Mason Taylor

Jets Expecting a "Hell of a Year" From Mason Taylor
Collin Morikawa

Withdraws From Valero Texas Open
PGA

Stephan Jaegar Still Looking For Consistency at Valero Texas Open
Nicolai Hojgaard

is Red-Hot Coming to TPC San Antonio
Tony Finau

a Risky Proposition at Valero Texas Open
Ludvig Aberg

Looks to Shake Off Collapse at Valero Texas Open
Jacob deGrom

Cleared for Season Debut on Tuesday
Colt Emerson

Signs an Eight-Year Extension with Mariners
James Conner

Role Threatened in Arizona?
Devin Neal

Dynasty Value Slipping Away?
Josh Downs

Headed for More Targets in 2026?
Mike Evans

Still Has WR1 Upside in New Home
William Nylander

Records Four Points Against Ducks
Macklin Celebrini

Becomes Sixth Teenager With 100-Point Season
Jaden Schwartz

Could Return Tuesday
Jordan Greenway

Available Tuesday
Jake Sanderson

Remains Out Tuesday
Cutter Gauthier

Exits Early Against Maple Leafs
Cale Makar

Sustains Upper-Body Injury Monday
Patrick Rodgers

Needs to Make More Birdies in San Antonio
Sepp Straka

Seeks Opportunity in San Antonio This Weekend
Nick Taylor

Could Again Struggle at the Valero Texas Open
Keith Mitchell

Sets Up Solidly for TPC San Antonio
Jose Altuve

Tallies Four Hits, Two Homers in Big Night
Rickie Fowler

a Boom-or-Bust Option at Valero Texas Open
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Scores Twice in Blowout Victory
Anthony Mantha

has Three-Point Performance on Monday
Miguel Vargas

Hits Grand Slam, Drives in Six in Win Over Miami
Tanner Bibee

to Start on Tuesday Against Dodgers
Aliaksei Protas

Won't Play Tuesday
Pavel Mintyukov

Returns to Action Monday
Radko Gudas

Ready to Face Maple Leafs
John Klingberg

to Remain Sidelined Monday
Matt McCarty

Seeking to Play into the Weekend in San Antonio
Brian Harman

Looking to Continue Form From The Players Championship
Steven Fisk

Attempting to String Better Rounds Together at San Antonio
Luke Clanton

Still Having Rough Time Contending at Events
Max Homa

Looks to Get Back on Track at Valero Texas Open
Chase Elliott

Takes Advantage of Pit Strategies for Second Career Martinsville Win
Denny Hamlin

Dominates but Finishes Second at Martinsville
Joey Logano

Bounces Back with Third-Place Finish at Martinsville
Ty Gibbs

Gains his Fourth Top-Five Finish of the Season at Martinsville
William Byron

Scores Another Top-Five Finish at Martinsville
Joe Pyfer

Extends His Winning Streak
Israel Adesanya

Loses Fourth Consecutive Fight
Maycee Barber

Suffers Her First Knockout Loss
Alexa Grasso

Scores Highlight-Reel Knockout
Niko Price

Retires After UFC Seattle Loss
Michael Chiesa

Victorious In His Retirement Fight
Julian Erosa

Suffers First-Round Knockout Loss
Lerryan Douglas

Scores First-Round Knockout Win In His UFC Debut
Alex Bregman

Clobbers First Two Homers in Sunday's Loss at Wrigley
Yandy Díaz

Yandy Diaz Records Five Hits, Drives in Four in Win Over Cardinals
Kyle Larson

Is Likely to Pay Off for DFS at Martinsville
Christopher Bell

Could Have Another Top-10 Performance At Martinsville
William Byron

Is A Threat to Win Again at Martinsville
Chase Elliott

is A Solid DFS Option for Martinsville Lineups
Chase Briscoe

has Plenty of Upside for DFS Lineups at Martinsville
Carlos Estévez

Carlos Estevez Unlikely to See High-Leverage Opportunities in Near Future
Jacob deGrom

Feels "Much Better," Hopeful he Can Start This Week
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Martinsville?
Ryan Preece

Is A Solid DFS Option for Martinsville Lineups
Josh Berry

Could Josh Berry Pay Off for Tournament DFS Lineups At Martinsville?
Carson Hocevar

May be Too Inconsistent to Start in Martinsville DFS Lineups
Austin Cindric

Is Austin Cindric Worth Rostering for DFS At Martinsville?
Denny Hamlin

the Favorite to Win at Martinsville
Ryan Blaney

Should Contend at Martinsville
Tyler Reddick

Should Come Back Down to Earth at Martinsville
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Will Be Strong at Martinsville
NASCAR

Bubba Wallace Looking to Rebound at Martinsville
Shane Van Gisbergen

Shane van Gisbergen Showing Progress, Qualifies Fifth at Martinsville
Dylan Cease

Fans 12 in Blue Jays Debut on Saturday
Andrew Vaughn

Needs Hand Surgery, Expected to be Out 4-6 Weeks
Jacob deGrom

"Confident" he Will Make his Next Start
Jacob deGrom

Scratched From Saturday's Start Due to Neck Stiffness
Jeferson Quero

Brewers Calling Up Catching Prospect Jeferson Quero
Deyvison De Los Santos

Marlins Promote Deyvison De Los Santos to Major Leagues
Shea Langeliers

Hits Two Home Runs on Opening Day
Kevin Gausman

Picks Up No-Decision But Strikes Out 11 on Opening Day
Tanner Bibee

Day-to-Day, Could Make his Next Start
Shane Baz

Orioles Agree to Five-Year Extension
Joe Pyfer

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Israel Adesanya

Returns At UFC Seattle
Maycee Barber

Looks To Extend Her Win Streak To Eight
Alexa Grasso

Looks To Get Back In The Win Column
Niko Price

In Dire Need Of Victory
Michael Chiesa

Set For Retirement Fight
Lerryan Douglas

Set For His UFC Debut
Julian Erosa

Looks To Bounce Back
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