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FanDuel MLB DFS Lineup Picks (9/21/18): Daily Fantasy Baseball Advice

The Cubs have returned to their regular schedule of playing in the afternoon on Fridays, so we're back to a 14 game Main slate - but it's an attractive one! We've got a number of household names on the bump and a lot of important baseball to be played still (tight division races!), so tonight should be interesting.

I'll jump into my picks in a second, but first, Vegas lines! We've got a handful of absolutely enormous moneyline favorites to take into consideration when building lineups, starting with the Yankees (-320), Dodgers (-272), Astros (-225), and Cardinals (-165). As for implied run totals, the Yankees are up top there as well at 5.9, followed by the Mariners (5.6), Rangers (5.0) and the Astros at 4.9.

In this article, I will be providing you with my daily fantasy baseball lineup picks for FanDuel on 9/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS lineup picks for DraftKings and other sports too. If you have any questions or comments, feel free to contact me up on Twitter @kpLuch.

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FanDuel DFS Pitcher

Gerrit Cole - SP, vs LAA ($10,800)

A lot of top tier options to sort through tonight and consider, but Cole gets the call for me as my number one. He's facing a team he's been dominant against this season and he's peformed above salary based expectations in four straight starts. He has one of - if not the - highest point floors among the talent group tonight and has the type of matchup where he should limit run scoring and has a bright strikeout outlook. This Angels squad only has an implied run total of 3.2 and their projected lineup not only has a 25% strikeout rate split, but a lowly .292 wOBA as well. Those are big reasons why the Astros are one of the biggest favorites on Friday with a -225 moneyline. Cole and his fantastic 12.3 K/9 can be used in all formats tonight.

Luis Castillo - SP, at MIA ($8,500)

Castillo has had a handful of dominant performances this month looking at things through a tounrament lense - he's struck out 11, 9 and 7 in three of his last four starts. Home runs (1.5 HR/9) certainly are still an issue for him, but the elite strikeout upside is there and he has a matchup to exploit tonight in Miami. This park should help him keep the ball in the yard, and facing a Miami team without much pop certainly helps as well - their current implied run total is just 3.5. He has a 8.9 K/9 on the season and faces a team with the sixth highest strikeout rate in the majors over the past month, one whose projected lineup has a 25% K rate against righties paired with a .288 wOBA. Castillo is a strong tournament option for me this evening.

Also Consider: Rich Hill - SP, vs SDP ($9,200)

FanDuel DFS Infielders

Mike Zunino - C, at TEX ($2,000)

We can get some Mariners bats in our cash game lineups tonight at incredibly low prices - which is made extra appealing by their park upgrade and 5.6 implied run total. Zunino's wOBA split is nothing to write home about (.303), but he does possess big power against righties, highlighted by a .238 ISO split this season.

Dan Vogelbach - 1B, at TEX ($2,200)

Vogelbach is pretty hot right now, blasting two home runs in his last four games and posting a 57% hard hit rate over the past week. The big lefty is in a good spot tonight against the righty Connor Sadzeck, who's making a spot start for the Rangers and doesn't really have MLB quality stuff. Vogelbach owns a strong .377 wOBA split and a .219 ISO.

Rougned Odor - 2B, vs SEA ($3,600)

The upside is high tonight for Odor and his left-handed hitting teammates in Arlington. Opposing start Erasmo Ramirez has been rattled by lefties this year, allowing a 43% hard contact rate, a .399 wOBA and a .642 slugging percentage. Odor brings a .200 ISO split to the dish and has an average exit velocity of 93 miles per hour these past two weeks.

Todd Frazier - 3B, at WAS ($2,700)

You won't hear me complaining that FanDuel gave us so many nice, low-priced cash game options on a day where we basically need to spend up on one of the elite pitching options. Frazier has been particularly strong in righty-righty matchups in 2018, posting .201 ISO split that is 96 points higher than his mark against lefties.

Didi Gregorius - SS, vs BAL ($3,900)

Didi gets a platoon advantage matchup in a great hitter's park and gives us exposure to the top projected offense for just under 4k - not a bad deal! Gregorius has a 42% hard hit rate over the past two weeks and a desirable .234 ISO split.

FanDuel DFS Outfielders

Shin-Soo Choo - OF, vs SEA ($3,700)

Choo has been tearing the cover off the ball in the past 10 days (66% hard hit rate, average exit velocity of 98 miles per hour) and draws a matchup to target tonight in Arlington. He has a high floor created by his strong .383 wOBA split and good power upside too, highlighted by his .215 ISO split in 2018.

Chris Taylor - OF, vs SDP ($3,000)

Taylor is a really nice value tonight, especially for a hitter who draws the platoon advantage and should be hitting out of the leadoff spot tonight for a team with a top-5 implied run total (4.8). He's posted a strong .203 ISO split against southpaws this season.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

P.J. Washington

is Ruled Out for Thursday's Contest
Jaime Jaquez Jr.

is Returning on Thursday
Daniel Jones

Colts Plan to Re-Sign Daniel Jones
Darius Garland

to Play on Thursday
Anthony Edwards

Active Thursday
Coby White

to Play with Minutes Limit on Thursday
Ace Bailey

Sidelined on Thursday
Kevin Huerter

Won't Play on Thursday
Andrew Nembhard

Won't Play on Thursday
Brandon Miller

is Cleared for Thursday's Game
LaMelo Ball

Upgraded to Available on Thursday
Kevin Love

Available For Thursday
Kawhi Leonard

Suffers Ankle Injury, Considered Questionable for Friday
Jamie Drysdale

Unavailable Against Maple Leafs
Bobby Brink

Sits Out Thursday
Simon Nemec

Back for Devils Thursday
Jusuf Nurkić

Jusuf Nurkic Questionable For Thursday Against Mavs
Troy Terry

Misses Thursday's Game
Alexis Lafrenière

Alexis Lafreniere Good to Go Against Sabres
Brad Marchand

Out Thursday
Ace Bailey

Considered Questionable Versus Dallas
Evgeni Malkin

Set to Return Thursday
Anthony Edwards

Questionable for Thursday
Davante Adams

Off the Injury Report, Will Play Against Carolina
Bo Bichette

Phillies to Meet With Bo Bichette
Rome Odunze

Will Return for Wild-Card Game on Saturday
CFB

DJ Lagway Commits to Baylor
Miami Dolphins

Dolphins Fire Head Coach Mike McDaniel
Matvei Michkov

Expected to Play Thursday
Alex Lyon

to Miss at Least One More Week
Mason Marchment

Placed on Injured Reserve, Out Week-to-Week
Alexis Lafrenière

Alexis Lafreniere Battling Illness, Iffy for Thursday
J.T. Miller

Likely to Return Thursday
Adam Henrique

Out Through Olympic Break
Dean Wade

Ruled Out Thursday
Brandon Williams

Questionable for Thursday
P.J. Washington

Doubtful Thursday
Jaime Jaquez Jr.

Questionable Thursday
Donovan Mitchell

Available Thursday
Corey Kispert

Hawks Land Corey Kispert
Sam LaPorta

Plans to be Back for Training Camp
Owen Caissie

Shipped to Miami as Centerpiece of Trade
Edward Cabrera

Cubs Officially Acquire Edward Cabrera From Marlins
Nathan Walker

Ready to End 16-Game Absence
Rutger McGroarty

Out Indefinitely With Concussion
Kevin Stenlund

a Game-Time Call Wednesday
Ty Dellandrea

Ruled Out Wednesday
Adam Erne

Misses Wednesday's Action
Tom Wilson

Aliaksei Protas Won't Play Wednesday
Anze Kopitar

Out Wednesday
Rome Odunze

Plans to Play on Saturday
Edward Cabrera

Cubs Finalizing Deal to Acquire Edward Cabrera From Marlins
New York Giants

Giants "All-In" on Hiring John Harbaugh
CFB

Jackson Arnold Signs with UNLV
CFB

Sam Leavitt Scheduled to Visit Tennessee
Devon Toews

to Miss at Least Two Weeks
New York Giants

John Harbaugh Expected to be Favorite to Become New Giants Head Coach
Baltimore Ravens

John Harbaugh Won't Return as Ravens Head Coach
Bo Bichette

Unlikely to Return to Toronto?
Jordan Love

Ready to Start in Wild-Card Game Against Bears
CFB

Jadan Baugh Staying with Florida for Junior Season
Washington Commanders

Commanders "Mutually" Parting Ways With OC Kliff Kingsbury
CFB

Byrum Brown Officially Commits to Auburn
CFB

Austin Simmons Signing with Missouri
CFB

Ty Simpson Undecided on 2026 Plans
CFB

Quarterback AJ Hill Following Ryan Silverfield to Arkansas
Atlanta Falcons

Falcons Have Requested an Interview With Klint Kubiak
Deshaun Watson

Browns Expect Deshaun Watson to be on the Team Next Year
Wan'Dale Robinson

Dealing With Fractured Ribs
Cam Skattebo

Hopes to be Back by Training Camp
Cameron Ward

Won't Need Surgery on his Shoulder
Davante Adams

Rams Expect Davante Adams to Return in Wild-Card Round
Arizona Cardinals

Cardinals Fire Head Coach Jonathan Gannon
Las Vegas Raiders

Raiders Fire Head Coach Pete Carroll
Malik Nabers

Unsure if He Will Be Ready for Week 1 of 2026 Season
CFB

Trinidad Chambliss Will Return to Ole Miss If Granted Sixth Year of Eligibility
Cincinnati Bengals

Zac Taylor Will Return as Bengals Head Coach in 2026
Bo Bichette

Phillies Have Interest in Bo Bichette
Kansas City Royals

Matt Quatraro Signs Three-Year Extension With Royals
CFB

Transfer QB Billy Edwards Commits to North Carolina
CFB

Sam Leavitt Visiting Texas Tech on Saturday
CFB

DJ Lagway Expected To Visit Florida State
Kyle Tucker

Blue Jays "Remain the Favorite" to Sign Kyle Tucker

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP